Chlorothiazide - Fda Prescribing Information, Side Effects And Uses, Tiazid

Chlorothiazide

Chlorothiazide is a diuretic and antihypertensive. It is 6- chloro-2 H -1,2,4-benzothiadiazine-7-sulfonamide 1, 1-dioxide. Its molecular formula is C 7 H 6 CIN 3 O 4 S 2 and its structural formula is:

Chlorothiazide, USP is a white, or practically white crystalline compound with a molecular weight of 295.73 which is very slightly soluble in water, but readily soluble in dilute aqueous sodium hydroxide. It is soluble in urine to the extent of about 150 mg per 100 mL at pH 7.

Each tablet for oral administration contains either 250 mg or 500 mg of Chlorothiazide and the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium-Type A, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate.

Chlorothiazide - Clinical Pharmacology

The mechanism of the antihypertensive effect of thiazides is unknown. Chlorothiazide does not usually affect normal blood pressure.

Chlorothiazide affects the distal renal tubular mechanism of electrolyte reabsorption. At maximal therapeutic dosages, all thiazides are approximately equal in their diuretic efficacy.

Chlorothiazide increases excretion of sodium and chloride in approximately equivalent amounts. Natriuresis may be accompanied by some loss of potassium and bicarbonate.

After oral use diuresis begins within 2 hours, peaks in about 4 hours, and lasts about 6 to 12 hours.

Pharmacokinetics and Metabolism

Chlorothiazide is not metabolized but is eliminated rapidly by the kidney. The plasma half-life of Chlorothiazide is 45 to 120 minutes. After oral doses, 10 to 15 percent of the dose is excreted unchanged in the urine. Chlorothiazide crosses the placental but not the blood-brain barrier and is excreted in breast milk.

Indications and Usage for Chlorothiazide

Chlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.

Chlorothiazide has also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.

Chlorothiazide is indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.

Use in Pregnancy

Routine use of diuretics during normal pregnancy is inappropriate and exposes mother and fetus to unnecessary hazard. Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful in the treatment of toxemia.

Edema during pregnancy may arise from pathologic causes or from the physiologic and mechanical consequences of pregnancy. Thiazides are indicated in pregnancy when edema is due to pathologic causes, just as they are in the absence of pregnancy (see PRECAUTIONS: Pregnancy ). Dependent edema in pregnancy, resulting from restriction of venous return by the gravid uterus, is properly treated through elevation of the lower extremities and use of support stockings. Use of diuretics to lower intravascular volume in this instance is illogical and unnecessary. During normal pregnancy there is hypervolemia which is not harmful to the fetus or the mother in the absence of cardiovascular disease. However, it may be associated with edema, rarely generalized edema. If such edema causes discomfort, increased recumbency will often provide relief. Rarely this edema may cause extreme discomfort which is not relieved by rest. In these instances, a short course of diuretic therapy may provide relief and be appropriate.

Contraindications

Hypersensitivity to this product or to other sulfonamide-derived drugs.

Warnings

Use with caution in severe renal disease. In patients with renal disease, thiazides may precipitate azotemia. Cumulative effects of the drug may develop in patients with impaired renal function.

Thiazides should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma.

Thiazides may add to or potentiate the action of other antihypertensive drugs.

Sensitivity reactions may occur in patients with or without a history of allergy or bronchial asthma.

The possibility of exacerbation or activation of systemic lupus erythematosus has been reported.

Lithium generally should not be given with diuretics (see PRECAUTIONS: Drug Interactions ).

Precautions

General

All patients receiving diuretic therapy should be observed for evidence of fluid or electrolyte imbalance: namely, hyponatremia, hypochloremic alkalosis, and hypokalemia. Serum and urine electrolyte determinations are particularly important when the patient is vomiting excessively or receiving parenteral fluids. Warning signs or symptoms of fluid and electrolyte imbalance, irrespective of cause, include dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, confusion, seizures, muscle pains or cramps, muscular fatigue, hypotension, oliguria, tachycardia, and gastrointestinal disturbances such as nausea and vomiting.

Hypokalemia may develop, especially with brisk diuresis, when severe cirrhosis is present or after prolonged therapy.

Interference with adequate oral electrolyte intake will also contribute to hypokalemia. Hypokalemia may cause cardiac arrhythmias and may also sensitize or exaggerate the response of the heart to the toxic effects of digitalis (e. g. increased ventricular irritability). Hypokalemia may be avoided or treated by use of potassium-sparing diuretics or potassium supplements such as foods with a high potassium content.

Although any chloride deficit is generally mild and usually does not require specific treatment except under extraordinary circumstances (as in liver disease or renal disease), chloride replacement may be required in the treatment of metabolic alkalosis.

Dilutional hyponatremia may occur in edematous patients in hot weather; appropriate therapy is water restriction, rather than administration of salt, except in rare instances when the hyponatremia is life-threatening. In actual salt depletion, appropriate replacement is the therapy of choice.

Hyperuricemia may occur or acute gout may be precipitated in certain patients receiving thiazides.

In diabetic patients dosage adjustments of insulin or oral hypoglycemic agents may be required. Hyperglycemia may occur with thiazide diuretics. Thus latent diabetes mellitus may become manifest during thiazide therapy.

The antihypertensive effects of the drug may be enhanced in the post-sympathectomy patient.

If progressive renal impairment becomes evident, consider withholding or discontinuing diuretic therapy.

Thiazides have been shown to increase the urinary excretion of magnesium; this may result in hypomagnesemia.

Thiazides may decrease urinary calcium excretion. Thiazides may cause intermittent and slight elevation of serum calcium in the absence of known disorders of calcium metabolism. Marked hypercalcemia may be evidence of hidden hyperparathyroidism. Thiazides should be discontinued before carrying out tests for parathyroid function.

Increases in cholesterol and triglyceride levels may be associated with thiazide diuretic therapy.

Laboratory Tests

Periodic determination of serum electrolytes to detect possible electrolyte imbalance should be done at appropriate intervals.

Drug Interactions

When given concurrently the following drugs may interact with thiazide diuretics.

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur.

Antidiabetic drugs (oral agents and insulin): Dosage adjustment of the antidiabetic drug may be required.

Other antihypertensive drugs: Additive effect or potentiation.

Cholestyramine and colestipol resins: Both cholestyramine and colestipol resins have the potential of binding thiazide diuretics and reducing diuretic absorption from the gastrointestinal tract.

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia.

Pressor amines (e. g. norepinephrine): Possible decreased response to pressor amines but not sufficient to preclude their use.

Skeletal muscle relaxants, nondepolarizing (e. g. tubocurarine): Possible increased responsiveness to the muscle relaxant.

Lithium: Generally should not be given with diuretics. Diuretic agents reduce the renal clearance of lithium and add a high risk of lithium toxicity. Refer to the package insert for lithium preparations before use of such preparations with Chlorothiazide.

Non-steroidal Anti-inflammatory Drugs: In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. Therefore, when Chlorothiazide and non-steroidal anti-inflammatory agents are used concomitantly, the patient should be observed closely to determine if the desired effect of the diuretic is obtained.

Drug/Laboratory Test Interactions

Thiazides should be discontinued before carrying out tests for parathyroid function (see PRECAUTIONS: General ).

Carcinogenesis, Mutagenesis, Impairment of Fertility

Carcinogenicity studies have not been done with Chlorothiazide.

Chlorothiazide was not mutagenic in vitro in the Ames microbial mutagen test (using a maximum concentration of 5 mg/plate and Salmonella typhimurium strains TA98 and TA100) and was not mutagenic and did not induce mitotic non-disjunction in diploid-strains of Aspergillus nidulans .

Chlorothiazide had no adverse effects on fertility in female rats at doses up to 60 mg/kg/day and no adverse effects on fertility in male rats at doses up to 40 mg/kg/day. These doses are 1.5 and 1 times (calculations based on a human body weight of 50 kg) the recommended maximum human dose, respectively, when compared on a body weight basis.

Pregnancy

Teratogenic Effects. Pregnancy Category C

Although reproduction studies performed with Chlorothiazide doses of 50 mg/kg/day in rabbits, 60 mg/kg/day in rats and 500 mg/kg/day in mice revealed no external abnormalities of the fetus or impairment of growth and survival of the fetus due to Chlorothiazide, such studies did not include complete examinations for visceral and skeletal abnormalities. It is not known whether Chlorothiazide can cause fetal harm when administered to a pregnant woman; however, thiazides cross the placental barrier and appear in cord blood. Chlorothiazide should be used during pregnancy only if clearly needed (see INDICATIONS AND USAGE ).

Chlorothiazide may cause fetal or neonatal jaundice, thrombocytopenia, and possibly other adverse reactions which have occurred in the adult.

Nursing Mothers

Because of the potential for serious adverse reactions in nursing infants from Chlorothiazide, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Pediatric Use

There are no well-controlled clinical trials in pediatric patients. Information on dosing in this age group is supported by evidence from empiric use in pediatric patients and published literature regarding the treatment of hypertension in such patients. (See DOSAGE AND ADMINISTRATION: Infants and Children .)

Geriatric Use

Clinical studies of Chlorothiazide did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.

This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function (see WARNINGS ).

Adverse Reactions

The following adverse reactions have been reported and, within each category, are listed in order of decreasing severity.

Body as a whole: Weakness.

Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics or antihypertensive drugs).

Digestive: Pancreatitis, jaundice (intrahepatic cholestatic jaundice), diarrhea, vomiting, sialadenitis, cramping, constipation, gastric irritation, nausea, anorexia.

Hematologic: Aplastic anemia, agranulocytosis, leukopenia, hemolytic anemia, thrombocytopenia.

Hypersensitivity: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, fever, urticaria, rash, purpura.

Metabolic: Electrolyte imbalance (see PRECAUTIONS ), hyperglycemia, glycosuria, hyperuricemia.

Musculoskeletal: Muscle spasm.

Nervous System / Psychiatric: Vertigo, paresthesias, dizziness, headache, restlessness.

Renal: Renal failure, renal dysfunction, interstitial nephritis (see WARNINGS ).

Skin: Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia.

Special Senses: Transient blurred vision, xanthopsia.

Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn.

Overdosage

The most common signs and symptoms observed are those caused by electrolyte depletion (hypokalemia, hypochloremia, hyponatremia) and dehydration resulting from excessive diuresis. If digitalis has also been administered, hypokalemia may accentuate cardiac arrhythmias.

In the event of overdosage, symptomatic and supportive measures should be employed. Emesis should be induced or gastric lavage performed. Correct dehydration, electrolyte imbalance, hepatic coma and hypotension by established procedures. If required, give oxygen or artificial respiration for respiratory impairment.

The degree to which Chlorothiazide sodium is removed by hemodialysis has not been established.

The oral LD 50 of Chlorothiazide is 8.5 g/kg, greater than 10 g/kg, and greater than 1 g/kg, in the mouse, rat and dog respectively.

Chlorothiazide Dosage and Administration

Therapy should be individualized according to patient response. Use the smallest dosage necessary to achieve the required response.

Adults

The usual adult dosage is 0.5 g to 1 g once or twice a day. Many patients with edema respond to intermittent therapy, i. e. administration on alternate days or on three to five days each week. With an intermittent schedule, excessive response and the resulting undesirable electrolyte imbalance are less likely to occur.

For Control of Hypertension

The usual adult starting dosage is 0.5 g or 1 g a day as a single or divided dose. Dosage is increased or decreased according to blood pressure response. Rarely some patients may require up to 2 g a day in divided doses.

Infants and Children

For Diuresis and For Control of Hypertension

The usual pediatric dosage is 5 to 10 mg per pound (10 to 20 mg/kg) per day in single or two divided doses, not to exceed 375 mg per day in infants up to 2 years of age or 1 g per day in children 2 to 12 years of age. In infants less than 6 months of age, doses up to 15 mg per pound (30 mg/kg) per day in two divided doses may be required. (See PRECAUTIONS: Pediatric Use .)

How is Chlorothiazide Supplied

Chlorothiazide tablets, USP are available containing 250 mg or 500 mg of Chlorothiazide, USP.

The 250 mg tablets are white, round, scored tablets debossed with M to the left of the score and 50 to the right of the score on one side of the tablet and blank on the other side. They are available as follows:

NDC 0378-0150-01 bottles of 100 tablets

The 500 mg tablets are white, round, scored tablets debossed with MYLAN above the score and 162 below the score on one side of the tablet and blank on the other side. They are available as follows:

NDC 0378-0162-01 bottles of 100 tablets

Store at 20° to 25°C (68° to 77°F). [See USP for Controlled Room Temperature.]

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Mylan Pharmaceuticals Inc. Morgantown, WV 26505

REVISED MARCH 2006 CTZ:R13

PRINCIPAL DISPLAY PANEL - 250 mg

Chlorothiazide Tablets, USP 250 mg

Rx only 100 Tablets

Each tablet contains: Chlorothiazide, USP 250 mg

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Keep container tightly closed.

Keep this and all medication out of the reach of children.

Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]

Usual Adult Dosage: See accom - panying prescribing information.

Mylan Pharmaceuticals Inc. Morgantown, WV 26505 U. S.A.

PRINCIPAL DISPLAY PANEL - 500 mg

Chlorothiazide Tablets, USP 500 mg

Rx only 100 Tablets

Each tablet contains: Chlorothiazide, USP 500 mg

Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

Keep container tightly closed.

Keep this and all medication out of the reach of children.

Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.]

Usual Adult Dosage: See accom - panying prescribing information.

Mylan Pharmaceuticals Inc. Morgantown, WV 26505 U. S.A.

Foamglas® Perinsul, Perinsyl

5.2 FOAMGLAS® PERINSUL

Load-bearing thermal insulation for masonry

Concrete deck

Mounting bituminous waterproofing membrane

FOAMGLAS® PERINSUL element, laid in a bed of mortar

FOAMGLAS® floor insulation

Partition wall (brickwork)

Cement / anhydrite screed

Outer wall (brickwork)

FOAMGLAS® insulation of base area

Exterior insulation, rendered

Advantages of the FOAMGLAS® system

Quality: Uniform thermal performance and load-bearing capacity (without additional support elements).

Cost efficiency: Efficient and well-priced solution for maximum thermal protection at minimal energy costs.

Sustainability: Optimum insulation and protection against moisture for generations.

Safety: The elements can easily be cut, assembled or used as smaller parts, without structural loss. There is no risk of damage from torch-applied bituminous waterproofing layers and contact with hot bitumen.

Functionality: Insulation and load-bearing element in one single functional layer. Prevents thermal bridges at the wall base. The insulation element can be combined with all commonly used type and size of bricks.

Technical data sheet

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Plavix - Blood Pressure, Clocardigel

Common use Specifically and actively inhibits aggregation of platelets (clotting) and dilatates coronary vessels. Plavix is used to diminish the risk of heart attacks and strokes caused by blood clots is increased in patients with a recent history of stroke, heart attach and peripheral vascular disease. It is used to prevent ischemic disorders like myocardial infarction, stroke, thrombosis of peripheral arteries and others.

Dosage and direction Plavix should be taken once a day with or without food.

Precautions As Plavix belongs to 'blood thinners' avoid taking it with aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) if your doctor did not recommend you to do it. Contact your doctor if you discovered that you have black or bloody stools, vomit that is similar to coffee grounds or if you cough up blood.

Hypersensitivity, severe liver failure, acute bleeding, ulcer of stomach or duodenum, ulcerous colitis, tuberculosis and other diseases predisposing to bleeding, pregnancy, breastfeeding, neonatal period. Caution should be exercised in patients with moderate liver of kidney failure.

Possible side effect Bleeding in stomach or guts, hemorrhagic stroke, neuropenia, thrombocytopenia, abdominal pain, dyspepsia, gastritis, constipation, ulcers in gastrointestinal tract, diarrhea, allergy.

Drug interaction The combination of Plavix with non-steroidal anti-inflammatory drugs may cause risk of stomach and intestinal bleeding the same as high concentration of Plavix increase concentration of Coumadin if they are used concurrently and lead to excessive bleeding.

Missed dose Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose Symptoms of a overdose are vomiting, feeling exhausted or shortness of breath, and signs of blood in your stools or vomit, diarrhea, rush, itching. In case of serious manifestation of these adverse reactions call your doctor immediately.

Storage Store Plavix tablets and capsules should be stored at room temperature between 15-30 C (59-86 F).

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Azaron, Azaron

Azaron

To this, related with Azaron application area there is in-depth information:

Other components

The following substance not effective components are part of the drug:

Sodium stearate

Propylene glycol

Water gereinigtes

How Azaron works

Azaron contains the active substance trip engelenburg Namin. Learn more on the applications and the action of trip engelenburg Namin below. Read also the information about the active range of H 1 – antihistamines, to which belongs the drug trip engelenburg Namin. Please note the special effect of Azaron is also

Application of the active substance: trip engelenburg Namin

Trip engelenburg Namin inhibits and removes the itching after insect bites and stings and insect bites. Also, it soothes the irritated skin after contact with jellyfish or nettles. Desweiteren lindert Tripelennamin storenden Juckreiz in der After - oder Genitalgegend.

Zu folgenden Anwendungsgebieten von Tripelennamin sind vertiefende Informationen verfugbar:

Wirkungsweise von Tripelennamin

Tripelennamin ist ein alteres mit antiallergischer Wirkung. Es wirkt weiterhin juckreizlindernd, rotungsmildernd, schmerzhemmend und quaddelbildungsunterdruckend an den betroffenen Hautstellen.

Dieser Wirkstoff zeichnet sich durch seine schnelle Aufnahme in den Korper aus. Damaged skin and especially infants and young children is likely to have a fast-track recording.

Special features of the effects of Azaron

The pen (5.75 grams) contains 115 milligrams trip engelenburg Namin-HCl. This corresponds to 100,63 milligrams trip engelenburg Namin.

Warnings & precautions

The medicinal product is no longer than a week apply.

Medicines can cause allergic reactions. Evidence for this can be: redness, runny nose, itching, swelling of the mucous membrane, itching and redness of the eyes, narrowing of the Airways (asthma). In rare cases, there may be allergic shock with loss of consciousness.

Should you perceive signs of an allergic reaction, immediately inform a doctor.

Side effects

What side effects can the active ingredient trip engelenburg Namin in Azaron have? Below, you will learn the most important thing possible, well-known side effects of trip engelenburg Namin in Azaron. These side effects should not occur, but can. Because everyone reacts differently to medications. Please also note that the side effects in type and frequency can vary depending on the drug form of the drug (for example, Tablet, syringe, ointment).

Side effects without specifying frequency: allergic skin irritation (such as redness and swelling), rash of light.

Specialties: For these or other hypersensitivity reactions the application to cancel and, if necessary, a doctor is to visit.

Dosage

The pen will be deleted once a day over the itchy skin range and slightly rubbed. Application period should be no longer than a week.

Contra-indications

The following information about contra-indications in the application of Azaron in General, pregnancy & lactation, and in children. It is important to note that the contra-indications can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

When may Azaron not be used?

Hypersensitivity to trip engelenburg Namin or other contributor anti-allergic fabrics, the active substance may not be applied.

The itchy skin is inflamed, it is also recommended by a local treatment.

What must you consider when pregnancy and breast-feeding?

Although no evidence of a fruit-damaging effect, trip engelenburg Namin should not be in the first three months of pregnancy. There are however no concerns against an application in breastfeeding.

What is taken into account in children?

Through the tender and delicate skin especially in infants and young children, the active ingredient is absorbed into the bloodstream faster. That is why he should be applied if at all, only very thin.

Interactions

Which of the active substance trip engelenburg Namin in Azaron interactions are known? It is important to note that the interactions can be different depending on the pharmaceutical form of the drug (for example, Tablet, syringe, ointment).

Interactions with other agents are still unknown.

Digestive Tract

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I have always believed that fanfiction is a great way of meeting and interacting with people from across the globe. I mean, here we're just people who appreciate knowledge and talent, irrespective of which country whoever belongs to. There is no discrimination and hatred in fanfiction. We don't go bandying about that one group is better than the other. Here, we are all equal.

That said, I believe in being courteous and polite to everyone. Please don't flame people. None of the writers here are getting paid to do what we do. You can't possibly derive any pleasure from hurting another person, especially since you don't even know that person.

Also, whenever you read a story and like it, leave a review. It's just common courtesy. An author, any author for that matter has put a lot of work into creating something we can all enjoy. It won't hurt to leave a few words of encouragement, even if it is as small as a "good job". Any good author will, of course, welcome constructive criticism.

I can proudly say that I do all these things. My sincere request to all of you is that you do the same.

When a girl is quiet, a million things are running through her mind.

When a girl is not arguing, she is thinking deeply.

When a girl looks at you with her eyes full of question, she is wondering how long you will be around.

When a girl answers "I'm fine." after a few seconds, she is not fine at all.

When a girl stares at you, she is wondering why you are lying.

When a girl rests her head on your chest, she is wishing for you to be her's forever.

When a girl wants to see you everday, she wants to be pampered.

When a girl says "I love you." she means it.

When a girl says "I miss you." nobody could miss you more than that.

Life only comes around once, so make sure you spend it with the right person.

Find a guy who calls you beautiful instead of hot, and calls you back when you hang up on him.

The guy who will stay awake just to watch you sleep.

Wait for the guy who kisses your forehead,

Who wants to show you off to the world when you are in your sweats.

The one who holds your hand in front of his friends and is constantly reminding you of how much he cares about you and how lucky he is to have you there for him.

The one who turns to his friends and declares "That's her."

I know for a fact that girls like that and guys like that are extremely hard to find in today's world. But when two such people come together, that is when you can see a forgotten thing called. true love.

Forehead . You'll be mine forever

Cheek . You mean so much to me

Shoulder . I want you

Holding Hands . We can learn to love each other

Wink . Let's get it on

Holding On Tight . I love you too much to let go

Looking in the Eyes . I'm so in love with you

Arm Around Waist . I'll show off my love for you

Spank on the Ass . That's mine. bitch XD

Laughing While Kissing . I am completly comfortable with you

FRIENDS: Never ask for anything to eat or drink. BEST FRIENDS: Helps themselves and are the reason why you have no food.

FRIENDS: Call your parents by Mr. and Mrs. and Grandpa, by Grandpa. BEST FRIENDS: Call your parents DAD and MOM and Grandpa, GRAMPS!

FRIENDS: Would bail you out of jail. BEST FRIENDS: Would be sitting next to you sayin "DAMN! We fucked up!"

FRIENDS: Have never seen you cry. BEST FRIENDS: Wont tell everyone else you cried. just laugh about it with you in private when your not down anymore.

FRIENDS: Asks you to write down your number. BEST FRIENDS: Has you on speed dial.

FRIENDS: Borrows your stuff for a few days then gives it back. BEST FRIENDS: Loses your shit and tells you, "My bad. here's a tissue."

FRIENDS: Only know a few things about you. BEST FRIENDS: Could write a very embarrassing biography on your life story.

FRIENDS: Will leave you behind if that is what the crowd is doing. BEST FRIENDS: Will kick the whole crowds ass that left you

FRIENDS: Would knock on your front door. BEST FRIENDS: Walk right in and say "I'M HOME."

FRIENDS: You have to tell them not to tell anyone. BEST FRIENDS: Already know not to tell.

FRIENDS: Are only through highschool/college. (aka: drinking buddies) BEST FRIENDS: Are for life.

FRIENDS: Will be there to take your drink away from you when they think you've had enough. BEST FRIENDS: Will look at you stumbling all over the place & say "Bitch drink the rest of that. You know we don't waste!

Why is it considered necessary to nail down the lid of a coffin?

Why don't you ever see the headline "Psychic Wins Lottery"?

Why doesn't glue stick to the inside of the bottle?

Why is it that doctors call what they do "practice"?

Why is the man who invests all your money called a broker?

Why can't they make the whole plane out of the same substance that little indestructible black box is?

Can fat people go skinny-dipping?

If a person with multiple personalities threatens suicide, is that considered a hostage situation?

If a cow laughed, would milk come out her nose?

So what's the speed of dark?

How come abbreviated is such a long word?

Since light travels faster than sound, isn't that why some people appear bright until you hear them speak?

Ever wonder what the speed of lightning would be if it didn't zigzag?

A bus station is where a bus stops. A train station is where a Train stops, On my desk I have a work station..

If quitters never win, and winners never quit, what fool came up with, "Quit while you're ahead"?

Should women put pictures of missing husbands on beer cans?

Why do they put pictures of criminals up in the Post Office?

How much deeper would oceans be if sponges didn't live there?

If you can't be kind, at least have the decency to be vague.

After eating, do amphibians need to wait an hour before getting OUT of the water?

Why don't they just make mouse-flavored cat food?

If you're sending someone some Styrofoam, what do you pack it in?

Why do they sterilize needles for lethal injections?

Is it true that cannibals don't eat clowns because they taste funny?

Isn't Disney World a people trap operated by a mouse?

Whose cruel idea was it for the word "lisp" to have an "s" in it?

Why can't you find fresh sardines in the fish market?

Why do so many old people eat at cafeterias?

Why does an "X" stand for a kiss?

Why does the word "Filipino" start with the letter F ?

Why are the copyright dates on movies and television shows written in Roman numbers?

Her name was Auroura She was only five This is what happened When she was alive

Her dad was a drunk Her mom was an addict Her parents kept her Locked in an attic

Her only friend was a little toy bear It was old and worn out And had patches of hair

She always talked to it When no one's around She lays there and hugs it Not a peep of sound

Until her parents unlock the door Some more and more pain She'll have to endure

A bruise on her leg A scar on her face Why would she be In such a horrible place?

But she grabs her bear And softly crys She loves her parents But they want her to die

She sits in the corner Quiet but thinking, "God, why? Why is My life always sinking?"

Such a bad life For a sad little kid She'd get beaten and beaten For anything she did

Then one night Her mom came home high The poor child was hit and slapped As hours went by

Then her mom suddenly Grabbed for a blade It was sharp and pointy One that she made

She thrusted the blade Right in her chest, "You deserve to die You worthless pest!"

The mom walked out Leaving the girl slowly dying She grabbed her bear And again started crying

Police showed up At the small little house They quickly barged in Everything was as quiet as a mouse

One officer slowly Opened a door To find the sad little girl Lying on the floor

It must have been bad To go through so much harm But at least she died With her best friend in her arms

If child abuse makes you sick and you think it's horrible and should be stopped, put this poem on your profile. no one should EVER have to endure this.

See that girl you just called fat? She is starving herself. You know that girl you just called ugly? She spends hours putting on make-up hoping people will like her. That boy you just tripped? He is abused enough at home. See that old man you made fun of cause of the ugly scars? He fought for your country. See that young boy you must made fun of for always being sick? He has to walk home in the snow cause his family is too poor. That guy you just made fun of for crying? His mother is dying.

Please stop bullying.

16 THINGS TO DO AT WAL-MART

1. Get 24 boxes of condoms and randomly put them in people's carts when they aren't looking.

2. Set all the alarm clocks in Electronics to go off at 5-minute intervals.

3. Make a trail of tomato juice on the floor leading to the rest rooms.

4. Walk up to an employee and tell him/her in an official tone, "'Code 3' in housewares". and see what happens.

5. Go the Service Desk and ask to put a bag of M&M's on lay away.

6. Move a 'CAUTION - WET FLOOR' sign to a carpeted area.

7. Set up a tent in the camping department and tell other shoppers you'll invite them in if they'll bring pillows from the bedding department.

8. When a clerk asks if they can help you, begin to cry and ask, "Why can't you people just leave me alone?"

9. Look right into the security camera & use it as a mirror, and pick your nose.

10. While handling guns in the hunting department, ask the clerk if he knows where the anti-depressants are.

11. Dart around the store suspiciously loudly humming the "Mission Impossible" theme.

12. In the auto department, practice your "Madonna look" using different size funnels.

13. Hide in a clothing rack and when people browse through say, "PICK ME, PICK ME!"

14. When an announcement comes over the loud speaker, assume the fetal position and scream, "NO! NO! It's those voices again!"

15. Go into a fitting room and shut the door and wait a while and then yell, very loudly, "There is no toilet paper in here!"

16. Get several bouncy balls and throw them down an aisle shouting "Pikachu, I choose you!"

Funny Quiz: Student got 0% in his exam even when he didn't get anything wrong.

Q1: In Which Battle Did Napoleon Die?

Ans: *In his last battle

Q2: Where Was The Declaration Of Independence Signed?

Ans: *At the bottom of the paper

Q3: River Ravi Flows In Which State?

Q4: What Is The Main Reason For Divorce?

Q5: What Is The Main Reason For Failure?

Q6: What Can You Never Eat For Breakfast?

Ans: *Lunch and Dinner

Q7: What Looks Like Half An Apple?

Ans: *the other half

Q8: If You Throw A Red Stone Into The Blue Sea, What Will It Become?

Ans: *It will simply become wet

Q9: How Can A Man Go Eight Days Without Sleeping?

Ans: *No problem, he sleeps at night

Q10: How Can You Lift An Elephant With One Hand?

Ans: *You will never find an elephant that only has one hand

Q11: It Took Eight Men Ten Hours To Build A Wall, How Long Will It Take Four Men To Build It?

Ans: *No time at all, the wall is already built

Q12: How Can You Drop An Egg On A Concrete Floor Without Cracking It?

Ans: *Any way you want, concrete floors are very hard to crack.

19 Ways to Maintain A Healthy Level Of Insanity

1. At lunch time, sit in your parked car with sunglasses on and point a hair dryer at passing cars. See if they slow down.

2. Page yourself over the intercom. Don't disguise your voice.

3. Every time someone asks you to do something, ask if they want fries with that.

4. Put your garbage can on your desk and label it "In."

5. Put decaf in the coffee maker for 3 weeks. Once everyone has gotten over their caffeine addictions, switch to espresso.

6. In the memo field of all your checks write, "for smuggling diamonds."

7. Finish all your sentences with "In accordance with the prophecy."

8. Don't use any punctuations.

9. As often as possible, skip rather than walk.

10. Order a diet water whenever you go out to eat, with a serious face.

11. Specify that your drive-through order is, "To go."

12. Sing along at the opera.

13. Go to a poetry recital and ask why the poems don't rhyme?

14. Put mosquito netting around your work area and play tropical sounds all day.

15. Five days in advance, tell your friends you can't attend their party because you're not in the mood.

16. Have your friends address you by your wrestling name, Rock Bottom.

17. When the money comes out the ATM, scream, "I won. I won!"

18. When leaving the zoo, start running towards the parking lot, yelling, "Run for your lives, they're loose!"

19. Tell your children over dinner, "Due to the economy, we are going to have to let one of you go."

FUN THINGS TO DO IN A ELEVATOR

1.When there's only one other person in the elvator, tap them on the shoulder and then pretend it wasn't you.

2.Say "Ding" on every floor.

3.Push the buttons and pretend they give you a shock. Smile, and go back for more.

4.Ask if you can push the button for other people, but push the wrong ones.

5.Call the Psychic Hotline from your cell phone and ask if they know what floor your on.

6.Hold the doors open and say your waiting for a friend. After a while, let the doors close, and say, "Hi Greg. How's your day been?"

7.Drop a pen and wait until someone goes to pick it up, then scream, "That's mine!"

8.Bring a camera and take pictures of everyone in the elevator.

9.Move your desk into the elevator and whenever anyone gets on, ask if they have an apointment.

10.Lay down the twister mat and ask people if they would like to play.

11.Leave a box in the corner, and when someone gets on, ask them if they can hear ticking.

12.Pretend you are a flight attendant and review emergency procedures and exits with the passengers.

13.Ask, "Did you feel that?"

14.Stand really close to someone, sniffing them occasionally.

15.When the doors close, announce to the others, "It's okay, don't panic, they open again!"

16.Swat at flies that don't exist.

17.Tell people that you can see their aura.

18.Call out, "Group Hug!"and then enforce it.

19.Grimace painfully while smacking your forehead and muttering, "Shut up, all of you, just shut up!"

20.Crack open your briefcase or purse, and while peering inside, ask, "Got enough air in there?"

21.Stand silently and motionless in the corner, facing the wall, without getting off.

22.Stare at another passenger for a while, then announce in horror, "Your one of THEM!" and back away slowly.

23.Wear a puppet on your hand and use it to talk to the other passengers.

24.Listen to the elevator walls with your stethoscope.

25.Make explosion noises when anyone presses a button.

26.Stare, grinning at another passenger for a while, then announce, "I have new socks on".

27.Draw a little square on the floor with chalk and announce to the other passengers, "This is MY personal space!"

28. Go up to them, and say in an Italian accent, "Germany, I can't tie my shoes, will you carry me??"

1. One tequila, two tequila, three tequila, floor.

2. Atheism is a non-prophet organization.

3. Can an atheist get insurance against acts of God?

4. If man evolved from monkeys and apes, why do we still have monkeys and apes?

5. The main reason that Santa is so jolly is because he knows where all the bad girls live.

6. I went to a bookstore and asked the saleswoman "Where's the self-help section?". She said if she told me, it would defeat the purpose.

7. What if there were no hypothetical questions??

8. If a deaf person signs swear words, does his mother wash his hands with soap?

9. If someone with multiple personalities threatens to kill himself, is it considered a hostage situation?

10. Is there another word for synonym?

11. Where do Forest Rangers go to "Get away from it all?"

12. What do you do when you see an endangered animal eating an endangered plant?

13. If a parsley farmer is sued, can they garnish his wages?

14. Would a fly without wings be called a walk?

15. Why do they lock the gas station bathrooms? Are they afraid someone will clean them?

16. If a turtle doesn't have a shell, is he homeless or naked?

17. Can vegetarians eat animal crackers?

18. If the police arrest a mime, do they tell him he has the right to remain silent?

19. What was the best thing before sliced bread?

20. One nice thing about egotists: they don't talk about other people.

21. How is it possible to have a civil war?

22. If one synchronized swimmer drowns, do the rest drown too?

23. If you ate both pasta and antipasto, would you still be hungry?

24. If you try to fail, and succeed in doing so, which have you done?

25. Whose cruel idea was it for the word "lisp" to have an "s" in it?

26. If you spin an oriental person in a circle three times, do they become disoriented?

1. We were given: Two hands to hold. Two legs to walk. Two eyes to see. Two ears to listen. But why only one heart? Because the other was given to someone else. For us to find.

2. "I reject your reality and substitute my own!"

3. You know what scares me about school? You can't write "Studying" without "dying"

4. It takes 42 muscles to frown, 28 to smile and only 4 to slap someone

5. Life isn't passing me by, its trying to run me over

6. There cannot be a crisis this week; my schedule is full

7. Everyone is the main character of their own story.

8. When going through life, it is better to have friends with you, rather than being alone.

9. I don't suffer from insanity, I enjoy every minute of it.

10. 'if who i am is what i have, and what i have is lost, then who am i?

11. "Sanity. Sorry, but I don't remember having such a useless thing in the first place."

12. The best life is having something worth dying for and living everyday as if it's your last.

13. "Never doubt that a small group of thoughtful, determined citizens can change the world. Indeed, it's the only thing that ever has."

14. I live in both Imagination and Reality, But my imagination conquers my world.

15. Call me crazy, but aren't we BOTH a little insane?

16. What's weird is normal and what's normal is weird

17. I dare you to try and follow my train of thought. I'll be there to laugh when you crash and burn.

18. When you do something stupid, it's just doing something insane. When you do something crazy, it's doing something insane, but it works.

19. It's not about the tools you use or the fame you have. It's about how well you can bring your dreams to life.

20. A Strong man stands for himself. A Stronger man stands for others

21. "No, vampires do NOT sparkle! 10 points from Hufflepuff!"

22. This story already belongs to us! When the story leaves the author’s hands, it already belongs to the reader.

23. If you are under the age of 17, or do not have the emotional and mental capacity to act in a mature way, get the hell out of this story. Hell, get the hell off the net, you pansies. (comment by moonlit mage)

24. 'Two things are infinite: the universe and human stupidity, and I'm not so sure about the universe' (darthwizard's Puppet Master, chapter 1)

25. " Insanity, you say it like it's a bad word " (The Swordslinger's Mahora's Mad Kitsune Hatter, chapter 1)

26. " Don’t knock on death’s door. Ring the bell and run. He hates that. "

According to the latest figures, 43 percent of all statistics are utterly worthless. Don't steal. The government hates the competition. If at first you don't succeed, change the rules. Tell the truth and run. Smile! It makes them wonder what you're up to. Friends come, and friends go, but enemies accumulate. Truth is stranger than fiction, because fiction has to make sense.. Power corrupts. Absolute power is kind of neat. Generally, generalizations are wrong. Ye shall know the truth, and the truth shall make ye mad. All things considered, insanity may be the only reasonable alternative. If we knew what we were doing, it wouldn't be research. Life is like a box of chocolates - it's full of nuts. The Truth is out there. So what are you doing here? If you can't beat them, join them. Then take over. Whatever you are, be a good one. You cannot shake hands with a clenched fist. You can never underestimate the stupidity of the general public. We are the people our parents warned us about. Freedom is the right to be wrong, not the right to do wrong. The difficulty is not so great as to die for a friend, as to find a friend worth dying for. Belief gets in the way of learning. If you try to fail and succeed, what have you done? When angry, count to four. When very angry, swear. Enjoy every minute of life. There's plenty of time to be dead. And in the end, it's not the years in your life that count, it's the life in your years. We don't live in the world of reality, we live in the world of how we percieve reality. If God had intended Man to smoke, he would have set him on fire. A single death is a tragedy. A million deaths is a statistic. Have the courage to live. Anyone can die. Education is important. School, however, is another matter. When a finger points at the moon, the imbecile looks at the finger. Fashion is a form of ugliness so intolerable that we have to change it every 2 months. Cynics are made, not born. Maybe this world is another planet's hell.

When in doubt, smile. It confuses people more than anything else.

Don't treat others as you want to be treated, treat others as they treat you.

When you’re down I may not be able to pick you back up, but I promise I’ll be willing to lay down right next to you.

I hear your silence loud and clear.

You laugh because I'm different. I laugh because you're all the same.

'It's okay if you want to drop dead.'

Some people are like Slinky's, useless, but fun to watch fall down the stairs.

'School prepares you for the real world, which sucks.'

'May God grant me the serenity to accept the things I cannot change, the courage to change the things I can, and a big bag of money.'

'I can only please one person per day. Today is not your day, and tomorrow does not look good either.'

Children in frontseats can lead to accidents. Accidents in backseats can lead to children.

Why do today what you could put off till tomorrow?

Education is important, school however, is another matter.

Don’t mess with me, I've got a stick.

If at first you don't succeed, don't try skydiving.

You cry, I cry, you laugh, I laugh, you fall off a cliff, I laugh even harder.

Evening News is where they begin with "Good Evening" then proceed to tell you why it isn't.

Don't follow in my footsteps, I tend to walk into walls

Sometimes I lie awake at night, and I ask, 'Where have I gone wrong?' Then a voice says to me, "This is going to take more than one night."

Build a man a fire, and he'll be warm for a day. Set a man on fire, and he'll be warm for the rest of his life.

"If toast always lands butter-side down, and cats always land on their feet, what happens if you strap toast on the back of a cat and drop it?

Help, I've fallen and I can't. Hey nice carpet!

Whose cruel idea was it for the word "Lisp" to have a "S" in it?

You have the right to remain silent. Anything you say will be misquoted, then used against you.

If one synchronized swimmer drowns, do the rest have to drown too?

If you try to fail, and succeed, which have you done?

They say hard work never hurts anybody, but why take the chance?

There’s a fine line between genius and insanity. I have erased this line.

Don't take life too seriously, you won't get out alive

Life is full of disappointments, and I'm full of life!

Always remember that you are absolutely unique. Just like everyone else.

Cheese…Milk's leap toward immortality.

The early bird may get the worm, but the second mouse gets the cheese.

Isn't it scary that doctors call what they do "practice"?

Why do they use sterilized needles for lethal injections?

Why do bankruptcy lawyers expect to be paid?

It is not MY fault that I never learned to accept responsibility

The real trouble with reality is that there's no background music.

Everyone is entitled to be stupid, but some abuse the privilege.

Sarcasm helps keep you from telling people what you really think of them.

The best things in the world are free -- and worth every penny of it.

Psychology. Mind over matter. Mind under matter? It doesn't matter. Never mind.

I haven't lost my mind -- it's backed up on tape somewhere.

Everything here is eatable. Even I'm eatable, but that is called cannibalism and is frowned upon in most societies.

Let's flip a coin. Heads, We'll be together, tails, we'll flip again.

Life isn't passing me by, it's trying to run me over.

Was that an earthquake, or did I just rock your world?

Why are the Force and ducktape the same? Both have a light and a dark side and hold the universe together.

You have to have darkness for a dawn to come.

Last night I looked up at the stars and matched each star to a reason I love you. I was doing fine until I ran out of stars.

To the world, you are just one person, but to one person, you are the world.

Charm is a way of getting the answer yes without asking a clear question.

Some minds are like concrete, thoroughly mixed and permanently set.

All things considered, insanity may be the only reasonable alternative.

When angry, count to ten, when very angry, swear.

I love deadlines. I like the whooshing sound as they go by.

Amateurs built the ark. Professionals built the Titanic. maybe we should have amateurs build everything.

If the sky is the limit, then what is space? Over the limit?

Why is it when an adult with the mind of a child is locked up and put in a asylum, while children are allowed to run in the streets?

Aren't the 'good things that come to those who wait' just the leftovers from the people that got there first?

If electricity comes from electrons, does morality come from morons?

Have you ever noticed that if you rearranged the letters in 'mother in law', they come out to 'Woman Hitler'?

Why is it when we talk to God we are praying, but when God talks to us we are crazy??

When life hands you lemons, throw those lemons right back at it and tell life to make its own dang lemonade.

Imitation is the most annoying form of flattery.

Always forgive our enemies - nothing annoys them so much.

If everything seems to be going well, you obviously overlooked something.

Join The Army, Visit exotic places, meet strange people, and then kill them.

Of course I'm talking to myself. Who else can I trust?

Let me know if anything I say offends you - I might want to offend you later.

One way to figure out how things work: push all the buttons!

I smile because I have no idea what's going on.

Life was so simple when girls had cooties. It's still pretty simple, but now I know they might have something much worse but still want to touch them

I used to be normal, until I met the freaks that I call my friends.

I ran with scissors and lived!

I agree with the dictionary. Girls before guys, partying before studying, and friends before love.

I don't obsess! I think intensely.

The greatest challenge in life is to find someone who knows all your flaws, differences, and mistakes, and yet still sees the best in you.

When life gives you lemons, make grape juice. Then sit back and watch the world wonder how you did it.

Those who don't learn from history are doomed to repeat it.

I'd rather be hated for who I am than be loved for who I'm not.

If you are on fanfiction. net for some other reason than writing pure romance fics or totally rearranging the original story because some slash romance story didn't happen, copy this and paste it onto your profile.

My favorite word is sarcasm.

It's a matter of life after death-now that he's dead, I have a life

Everyone has a wild side-me and my friends just prefer to make them public

I've got ADD and magic markers. Oh, the fun I will have.

There are 3 reasons to go through the day: Coffee in the morning, friends in the afternoon, and a good book for the rest of the day.

Oops, I appear to have fallen on your lips.

Note to Self: Normal is just a setting on washing machines.

Somebody needs a Happy Meal.

Music is like candy-you throw away the rappers.

I would be more scared if you were aiming for the person next to me

Do not use an axe to kill a fly on your friends' head.

My heart is not a playground

I find "good morning" a contradiction of terms

I'm not so good at advice. Can I interest you in a sarcastic comment?

If annoyed further, I shall spork your eyes out.

If you don't like me, there is nothing I can do. Here's a newsflash Honey, I don't live to please you.

Love can come in many different colours.

What is easy is not always right, and what is right is not always easy.

"So I'm crazy just because YOU have a leprechaun dancing on the ceiling?!"

"It has logic. I couldn't find any, but it still has logic."

"GREAT! Now I'm on fire! Are you happy now, ARE YOU!?"

"I'm not high, I'm insane. There's a difference you know."

"Perfection is an impossibility for humanity, for the simple fact humans themselves are imperfect. The ideal that things in our world are perfect, are simply ideals that are mistruths conjured up by madmen attempting to sustain that pitiful existence. It is impossible for us to understand what is perfect, for we are not perfect ourselves. Once humanity realizes this, we can all get on with our lives."

"Stop fighting against the system, destroy it from the inside. That's what germs do!"

"The children will inherite the earth. Your parents are terrified."

"Every second a million opportunities open, and every second, a million opportunities close."

"Ya, I have a voice in my head. It's called my conscience."

Heaven doesn't want me, and Hell's afraid I'll take over.

The cops never find it as funny as you do.

Education is important, school however, is another matter.

Don't look at me in that tone!

I'm not afraid of death. What's it going to do? Kill me?

I'm so gangster, I carry a squirt gun.

Therapist = The/rapist. Scary thought.

Remember what you just said, because tomorrow I am going to have a witty and sarcastic comeback and you'll be devastated then!

I'm not insane and the voices in my head agree with me.

I called your boyfriend gay and he hit me with his purse

Evening News is where they begin with "Good Evening" then proceed to tell you why it isn't

I'm sarcastic, what's your superpower?

A friend is a person that knows you are a good egg, even though you are slightly cracked.

What doesn't kill me better run pretty dang fast.

Yesterday is history, tomorrow is a mystery, and today is a gift--that's why we call it the present.

Have you noticed that anybody driving slower than you is an idiot, and anybody driving faster is a maniac?

I can insult my best friend, but heaven help you if you do.

Knowledge is knowing that a tomato is a fruit, wisdom is not putting it into a fruit salad.

Always forgive your enemies. Nothing annoys them more

If you don't like me, there is nothing I can do. Here's a newsflash Honey, I don't live to please you!

Before you judge a man, walk a mile in his shoes. After that, who cares. He's a mile away and you've got his shoes.

I can only please one person per day. Today is not your day. Tomorrow isn't looking so good either.

I'm sorry, yesterday was the deadline for all complaints.

If at first you DO succeed, try not to look to impressed.

Anger is one letter short of danger.

One day your prince will come. Mine? Oh, he just took a wrong turn, got lost, and is to stubborn to ask directions.

Excuse me. have you seen my sanity. I think I lost it.

If scientists were ever going to figure out how to travel through time, wouldn’t we now be seeing people from the future?

If our body temperature is normally 98.6 degrees, how come when it's 98 degrees outside, no one is comfortable?

Since a running back runs forward, why is he called a running back?

Why is "number" abbreviated as "no"? When there is no "o" in number?

Why do we teach kids that violence is not the answer and then have them read about wars in school that solved America's problems?

If a bunch of cats jump on top of each other, is it still called a dog pile?

When a boy is named after his dad, he is called 'Junior,' but what do you call a girl that is named after her mother?

If your name is Mr. Crunch, and you joined the Navy, would you eventually be Captain Crunch?

If all of the Acme stuff doesn't work, why does Wile Coyote keep buying their products?

364 days of the year, parents tell their kids not to take candy from strangers, yet on Halloween, its encouraged! Why is that ?

If pinochio said "my nose will grow now" what will eventualy happen?

FANFICTION - UNITED NATIONS. Has anyone else noticed how a lot of us get along and make friends on here and we can be from completely different countries? WTF. We're here making world peace on the INTERNET and we have all those ambassadors and senators and whatever struggling with it. If you realize this (or read this and agreed) copy and paste this and add your name and country (country is optional) to the list. SPREAD THE PEACE. Naruto-fan-Okami-chan (USA), NaraTemari011 (Puerto Rico), Lala girl in Lalaland (USA), Kakashi Forever (England), NinjasWillRuleTheWorld (Australia),Shadowtheangel (Sweden), Ice Prince Hitsugaya (USA), Gaara of the Desert564 (USA), RebeccaUlquiorraCifer23 (USA), TheCursedOne (Colombia) Sheened (UK) Shadowed (UK) DrewTheSeagull (USA), ThatGalladeAcrossTheStreet (USA), Azaron(India)

Sort: Category. Published. Updated. Title. Words. Chapters. Reviews. Status .

The Dementor attack on Harry during the summer after his fourth year leaves him on the verge of having his wand snapped. Unwilling to leave anything to chance, Sirius Black sets events into motion which will change Harry's life forever. HP/HG/FD

Harry Potter - Rated: M - English - Drama/Romance - Chapters: 81 - Words: 751,333 - Reviews: 5975 - Favs: 7,952 - Follows: 6,522 - Updated: 2/16 - Published: 1/19/2010 - Harry P. Hermione G. Fleur D. - Complete

Starts right after the Sasuke Retrieval, Jiraiya takes Naruto on a three year training trip. Taking his training seriously Naruto strives to become the best he can and learn everything that Konoha denied him. Naruto/Harem

Naruto - Rated: M - English - Adventure/Romance - Chapters: 28 - Words: 392,244 - Reviews: 2587 - Favs: 6,721 - Follows: 5,660 - Updated: 1/29 - Published: 8/9/2010 - Naruto U.

Sequel to Wastelands! Time has all but run out for Harry Potter. There are no more second chances. No more desperate bids for salvaged redemption. The game has changed, and in the end Harry will learn that the cost of his defiance has never run so high.

Harry Potter - Rated: T - English - Adventure/Fantasy - Chapters: 16 - Words: 67,498 - Reviews: 1183 - Favs: 1,844 - Follows: 2,074 - Updated: 1/18 - Published: 9/15/2010 - Harry P. Fleur D.

Daphne Greengrass always had a plan. She liked being organized. But the Dark Lord's return at the end of her fifth year derailed everything, and now she must decide who will best help her find the life she always wanted.

Harry Potter - Rated: M - English - Romance - Chapters: 20 - Words: 206,309 - Reviews: 1444 - Favs: 2,708 - Follows: 1,783 - Updated: 1/3 - Published: 4/27/2011 - Harry P. Daphne G. - Complete

Starts off from the Quidditch world cup, Harry finds a more important reason to fight for and that sometimes, a fairytale or legend is a lot more than it seems. Discontinued. Sorry.

Harry Potter - Rated: M - English - Romance/Hurt/Comfort - Chapters: 33 - Words: 395,578 - Reviews: 4333 - Favs: 6,875 - Follows: 7,065 - Updated: 9/8/2015 - Published: 5/20/2012 - Harry P. Fleur D. - Complete

It's a whole new world. A world were Pokemon and their trainers are something to be feared. This is the story of a new trainer who must survive his new life as a Pokemon trainer and leave the life that he has known behind. Watch as he struggles through a Pokemon world unlike any that you know. AU Pokemon World.

Pokemon - Rated: T - English - Chapters: 28 - Words: 102,371 - Reviews: 198 - Favs: 164 - Follows: 172 - Updated: 8/5/2015 - Published: 11/15/2013

Harry, still coming to terms with the reality of his destiny, and only just beginning to understand his greatest foe finds himself the unintended recipient of a magical bond between himself and one Gabrielle Delacour. An epic AU story beginning in the middle of sixth year, follows harry as one dramatic event leads him down a spiral path of debauchery and discovery.

Harry Potter - Rated: M - English - Adventure/Romance - Chapters: 18 - Words: 186,458 - Reviews: 182 - Favs: 950 - Follows: 1,116 - Updated: 3/28/2015 - Published: 2/19/2014 - Harry P. Hermione G. Ginny W. Gabrielle D.

Harry helps Fleur in the second task of GOF and pays the price. HP/Fleur/Gabrielle/Hermione. A Veela bonding fic based on love. T Rated and it will stay that way. Thirteen year old Almost fourteen Gabrielle to start the story. Good Dumbledore.

Harry Potter - Rated: T - English - Romance - Chapters: 52 - Words: 406,650 - Reviews: 4519 - Favs: 7,522 - Follows: 8,062 - Updated: 2/16/2015 - Published: 9/26/2009 - Harry P. Hermione G. Fleur D. Gabrielle D.

At age 10 Naruto gets a Doujutsu that lets him charm any woman. Alternate Universe and Characters, Fem Kyuubi, Power Naruto, Naru/Hina harem, straight/lez lemons and other adult stuff.

Naruto - Rated: M - English - Romance/Humor - Chapters: 18 - Words: 67,489 - Reviews: 576 - Favs: 2,311 - Follows: 1,948 - Updated: 11/16/2014 - Published: 1/17/2010 - Naruto U.

After the events of the DOM Harry & co return for the last week of term. But then Draco puts a curse on Harry that never been cured before. Can Hermione free him, with a little help from her other friends? eventual HarryHarem

Harry Potter - Rated: M - English - Romance/Drama - Chapters: 49 - Words: 382,170 - Reviews: 4432 - Favs: 5,738 - Follows: 6,594 - Updated: 10/31/2014 - Published: 7/30/2010 - [Harry P. Hermione G. Susan B. Daphne G.]

With Lord Voldemort on the rise, the Wizarding world turns to their only hope. Michael Potter? While the 'Boy Who Lived' takes in the fame, his long forgotten twin brother has become more then the world could have imagined.

Harry Potter - Rated: M - English - Adventure/Romance - Chapters: 34 - Words: 142,004 - Reviews: 1660 - Favs: 4,285 - Follows: 2,614 - Updated: 7/6/2014 - Published: 12/31/2010 - Harry P. - Complete

Issei Hyoudou is a second year Highschool Student at Kuou academy. He likes to finger paint and be by himself. His life changes after he hears one sentence. Rated M for Lemons, Nudity, Language, Violence, Perversion and awesomeness. Ise x Harem pairing. Current Harem: Akeno, Rias, Koneko, Ophis. More may come.

High School DxD/??????D?D - Rated: M - English - Adventure/Romance - Chapters: 39 - Words: 77,556 - Reviews: 368 - Favs: 735 - Follows: 498 - Updated: 4/22/2014 - Published: 3/12/2014 - H. Issei, Rias G. H. Akeno, T. Koneko - Complete

Students are required to write to a pen pal in the spirit of 'International Cooperation.' New friendships and a new romance arise going into the fourth year at Hogwarts.

Harry Potter - Rated: M - English - Romance - Chapters: 21 - Words: 189,865 - Reviews: 2160 - Favs: 5,453 - Follows: 2,726 - Updated: 6/25/2012 - Published: 12/6/2010 - Harry P. Fleur D. - Complete

What do you do when you are stuck on an island with plenty of food and water, and the only company you have is a beautiful woman? Naruto is about to find out. Sequel in the works.

Naruto - Rated: M - English - Romance - Chapters: 30 - Words: 783,233 - Reviews: 698 - Favs: 2,901 - Follows: 1,429 - Updated: 4/30/2012 - Published: 11/12/2007 - Naruto U. - Complete

On that fateful day, two Potters were born. One was destined to be the Boy-Who-Lived. The other was forgotten by the Wizarding World. Now, as the Triwizard Tournament nears, a strange boy is contracted to defend a beautiful girl.

Harry Potter - Rated: M - English - Adventure/Romance - Chapters: 19 - Words: 159,330 - Reviews: 3669 - Favs: 9,333 - Follows: 9,320 - Updated: 4/29/2012 - Published: 9/22/2011 - Harry P. Fleur D.

Harry takes a moment to help another Champion during the Second Task, and the unexpected aftermath forever changes his life.

Harry Potter - Rated: T - English - Adventure/Romance - Chapters: 21 - Words: 82,370 - Reviews: 3087 - Favs: 7,325 - Follows: 7,555 - Updated: 10/26/2010 - Published: 7/25/2010 - [Harry P. Fleur D.]

Take a deep breath, count back from ten… and above all else – don't worry! It'll all be over soon. The world, that is. Yet for Harry Potter the end is just the beginning. Enemies close in on all sides, and Harry faces his greatest challenge of all - Time.

Harry Potter - Rated: T - English - Adventure - Chapters: 31 - Words: 282,609 - Reviews: 3013 - Favs: 4,388 - Follows: 2,395 - Updated: 8/4/2010 - Published: 2/12/2008 - Harry P. Fleur D. - Complete

It's been done, but here's my shot at the old Marriage Contract type story. Harry and Daphne Greengrass find out their parents put together a marriage contract when they were born, now they must deal with it.

Harry Potter - Rated: M - English - Romance/Adventure - Chapters: 26 - Words: 150,027 - Reviews: 1593 - Favs: 5,286 - Follows: 2,114 - Updated: 3/17/2010 - Published: 12/21/2009 - Harry P. Daphne G. - Complete

He was abandoned by those he loved, ruined by corruption, and lost in what had become his life. But Hope is a strange thing. Harry's been hiding something and when it is revealed the world will quake in the pain of change. HP/FD/GD, post 5th year, non-Cano

Harry Potter - Rated: M - English - Adventure - Chapters: 36 - Words: 190,456 - Reviews: 1225 - Favs: 3,010 - Follows: 2,993 - Updated: 12/25/2009 - Published: 8/22/2008 - Harry P. Fleur D.

Following the events of the Goblet of Fire, Harry spends the summer with the Grangers, his relationship with Hermione deepens, and he and Hermione become animagi.

Harry Potter - Rated: M - English - Romance/Drama - Chapters: 68 - Words: 323,186 - Reviews: 4336 - Favs: 8,190 - Follows: 2,334 - Updated: 3/30/2007 - Published: 10/6/2006 - Harry P. Hermione G. - Complete

COMPLETE Edit in process. PostOOTP, Very Little of HBP. Harry returns to Privet Drive and Tonks helps him become the man and hero he must be to survive. HONKS. Action, Violence, Language and Sexual Situations

Harry Potter - Rated: M - English - Adventure/Romance - Chapters: 19 - Words: 332,503 - Reviews: 2578 - Favs: 7,169 - Follows: 2,835 - Updated: 5/13/2006 - Published: 9/5/2005 - Harry P. N. Tonks - Complete

The Triwizard is expanded to include duelling and quidditch tournaments. While the magical world prepares for the most exciting tournament in history, Voldemort is nearing resurrection and Harry Potter finds himself in the middle of it all. A thrilling tale of veelas, dragons, quidditch, friendship and a love that beats all. Harry and two veelas. Smart, trained Harry. HP/FD/OFC

Harry Potter - Rated: M - English - Romance/Adventure - Chapters: 8 - Words: 59,765 - Reviews: 708 - Favs: 1,775 - Follows: 2,476 - Updated: 12/24/2014 - Published: 7/3/2013 - [Harry P. Fleur D.]

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Bendit, planchas de asar.

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Mefenamic Acid 500mg Tablets, Topgesic

MEFENAMIC ACID 500MG TABLETS

12 mm 3 Tab/Glue

12 mm 3 Tab/Glue

MEFenAMIC ACID # 500 mg tablets

MEFenAMIC ACID # 500 mg tablets

Leaflet outside (Prima)

If you have any further questions on the use of this product, ask your doctor or pharmacist. 4. POSSIBLE SIDE EFFECTS Like all medicines, Mefenamic Acid can cause side effects, although not everybody gets them. Stop taking the tablets and tell your doctor immediately or go to the casualty department at your nearest hospital if the following happens: • an allergic reaction (swelling of the lips, face or neck leading to severe difficulty in breathing; asthma or worsening of existing asthma, skin rash or hives)

Stop taking the tablets and seek immediate medical help if the following happens at any time during your treatment: • pass blood in your faeces (stools/motions) • pass loose stools • pass black tarry stools • vomit any blood or dark particles that look like coffee grounds. Stop taking the tablets and tell your doctor if the following happens: • indigestion or heartburn • stomach pain or other abnormal stomach symptoms. The following side effects have also been reported: Gastro-intestinal: • loss of appetite, inflammation or ulceration of the mouth e. g. mouth ulcers or cold sores, peptic ulcer with or without bleeding, oily appearance of stools, feeling sick, being sick, wind, constipation, chest pain due to stomach acidity, abdominal pain, worsening of colitis or

Leaflet inside (Sekunda) 12 mm 65 mm Tab/Glue Page 1 Front page outside MEFENAMIC ACID 500 mg TABLETS PACKAGE LEAFLET: INFORMATION FOR THE USER Read all of this leaflet carefully before you start taking this medicine. • Keep this leaflet. You may need to read it again. • If you have any further questions, ask your doctor or pharmacist. • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. • If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. 1. 2. 3. 4. 5. 6.

IN THIS LEAFLET: What Mefenamic Acid is and what it is used for Before you take Mefenamic Acid How to take Mefenamic Acid Possible side effects How to store Mefenamic Acid Further information

1. WHAT MEFENAMIC ACID IS AND WHAT IT IS USED FOR Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which is used to relieve pain, swelling, and fever.

Crohn’s disease, intestinal inflammatory disease. inflammation of the stomach and inflammation of the pancreas, which causes severe pain in the abdomen and back. Elderly and debilitated patients seem to tolerate bleeding in the digestive track or ulceration less well than other patients. Greater caution should be taken when Mefenamic Acid is being taken by this group of patients. Metabolism and nutritional: • glucose intolerance in diabetic patients • low blood levels of sodium which can cause tiredness and confusion, muscle twitching, fits or coma. Psychiatric: • confusion, depression, hallucination, nervousness. Eye: • eye irritation, temporary loss of colour vision, problems with sight. Ear: • ear pain, ringing in the ears and a feeling of dizziness or “spinning”. Respiratory: • asthma, shortness of breath.

65 mm Page 2 Mefenamic Acid is used: • to treat headache, toothache, menstrual pain, muscular pain and to help reduce excessive menstrual bleeding • for long-term relief of pain and stiffness in rheumatoid arthritis and osteoarthritis • to treat pain after an operation or giving birth. 2. BEFORE YOU TAKE MEFENAMIC ACID DO NOT take Mefenamic Acid and consult your doctor if you: • are allergic (hypersensitive) to Mefenamic Acid or any of the other ingredients of this medicine, aspirin or any other NSAID e. g. ibuprofen • are taking aspirin or any other NSAID, including cyclo-oxygenase-2-specific inhibitors • have severe liver or kidney problems • have severe heart failure, which can cause shortness of breath or ankle swelling • are in the final 3 months of pregnancy • have or have ever had, peptic ulceration (ulcer in your stomach or duodenum) • have or have ever had bleeding in your digestive tract when you have taken NSAIDs in the past

Cardiovascular: • water retention, which may result in swollen ankles, high blood pressure and heart failure • medicines such as Mefenamic Acid may be associated with a small increased risk of heart attack (“myocardial infarction”) or stroke • palpitation, low blood pressure. Kidney: • kidney problems including inflammation of the kidneys, difficulty in passing urine or painful urination, presence of blood in urine, increased amounts of protein in the urine, kidney disease, kidney toxicity and kidney function failure. Liver: • abnormal liver function tests, inflammation of the liver and jaundice (yellowing of the skin or whites of the eyes), toxicity that damages the liver, rapid deterioration of kidney function due to liver failure. Nervous system: • hazy vision, inflammation of the optic nerve, headaches, pin-and-needles or numbness, dizziness, fits, tiredness, drowsiness, difficulty in sleeping and a general feeling of being unwell • aseptic meningitis (symptoms include stiff neck, headache, nausea, vomiting, fever and disorientation).

Blood: • reduction in red blood cells, which may cause paleness or yellowing of the skin and can also cause weakness or breathlessness (this generally stops after discontinuation of Mefenamic Acid), reduction in other blood cell counts, impaired blood cell production which may result in anaemia and reduced ability to fight infection and bruising or bleeding, decreased blood platelet counts, decreased white blood cell counts with a risk of getting infection more easily, infection in the blood stream, blood disorders, which may be characterised by fever or chills, sore throat, ulcers in your mouth or throat and blood clotting disorders. Skin: • sensitivity to light, swelling of the voice box, red rash, serious illness with blistering of the skin, mouth and eyes, sweating, itching and nettle rash. General: • tiredness, general feeling of being unwell, multi-organ failure and fever. Effects on your test result: • a positive result in certain tests for bile (a digestive juice secreted by the liver) in the urine of patients receiving Mefenamic Acid has been demonstrated to be due to the presence of this medicine and not to the presence of bile.

65 mm Page 3 • have inflammation of your bowels. This medicine should not be taken for the treatment of pain after heart bypass surgery. Take special care with Mefenamic Acid Talk to your doctor before you start to take this medicine if you: • are elderly • are suffering from or have a history of bronchial asthma • suffer from high blood pressure • have heart failure or any other heart or vascular problems • have mild kidney or liver problems • suffer from ulcerative colitis or Crohn’s disease • suffer from systemic lupus erythematosus (inflammation of the connective tissue) or mixed connective tissue disease • suffer from epilepsy • are elderly and suffering from dehydration or kidney problems • start developing rash, diarrhoea or a blood disorder or blood clotting problems after taking this medicine, please speak to your doctor immediately.

65 mm Page 4 This medicine should be given with caution to patients with internal brain bleeding or abnormal bleeding disorders. If this medicine fails to cure your menstrual pain or prolonged heavy menstrual bleeding please speak to your doctor immediately. Prolonged use of this medicine for the treatment of headache can make them worse. Please speak to your doctor if this happens to you. Medicines such as Mefenamic Acid may be associated with a small risk of heart attack (“myocardial infarction”) or stroke. Any risk is more likely with high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment. If you have heart problems, previous stroke or think that you might be at risk of these conditions (for example if you have high blood pressure, diabetes, or high cholesterol or are a smoker) you should discuss your treatment with your doctor or pharmacist. Taking other medicines DO NOT take Mefenamic Acid in combination with the following: • aspirin or any other NSAID (e. g. ibuprofen), including cyclo-oxygenase-2-specific inhibitors (e. g. celecoxib, meloxicam).

If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. 5. HOW TO STORE MEFENAMIC ACID Keep out of the reach and sight of children. Store below 25°C. Store in the original package. Do not transfer them to another container. Do not use Mefenamic Acid after the expiry date that is stated on the outer packaging. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment. 6. FURTHER INFORMATION What Mefenamic Acid Tablets contain: • The active ingredient is Mefenamic Acid 500 mg • The other ingredients are microcrystalline cellulose, calcium phosphate, croscarmellose sodium, povidone, sodium lauryl sulfate and stearic acid. The coating contains hypromellose, macrogols, and the colours quinoline yellow (E104), iron oxide yellow (E172), sunset yellow (E110) and titanium dioxide (E171).

65 mm (Front page outside)

What Mefenamic Acid Tablets look like and contents of the pack: • Mefenamic Acid 500 mg Tablets are pale yellow, ovoid, film-coated tablets. They are engraved ‘3P2’ on one side and plain on the reverse • The tablets are available in pack sizes of 7, 10, 14, 21, 28, 30, 50, 56, 60, 84, 90, 100, 110, 112, 120, 150, 160, 168, 250, and 500. Not all pack sizes may be marketed. Marketing Authorisation Holder and Manufacturer The Marketing Authorisation holder and company responsible for manufacture is TEVA UK Limited, Eastbourne, BN22 9AG. This leaflet was last revised: March 2011 PL 00289/0235

MEFenAMIC ACID 500 # 500 mg tablets

500 mg Tablets Oral Use

Talk to your doctor if you are taking any of the following: • anticoagulants and antiplatelet agents (medicine used to reduce and/or prevent blood clots) e. g. warfarin, heparin • diuretics ('water tablets') and antihypertensives (used to reduce your blood pressure) • drugs that stimulate your heart (e. g. digoxin) • ACE inhibitors and Angiotensin II receptor antagonists (both are used to treat high blood pressure e. g. enalapril, losartan) • aminoglycoside (used to treat bacterial infection) e. g. gentamycin • oral medicines for the treatment of high blood sugar e. g. tolbutamide • lithium, or SSRI medicines (e. g. fluoxetine, used in the treatment of depression) • methotrexate (used to treat cancer) • ciclosporin or tacrolimus (used to prevent organ transplants being rejected) • mifepristone in the last 8-12 days (used to terminate a pregnancy) • probenecid (used for the treatment of painful inflammation of toes and feet) • corticosteroids (e. g. hydrocortisone or prednisolone), or steroids (e. g. aldosterone)

• quinolone antibiotics (e. g. ciprofloxacin, norfloxacin or levofloxacin) • zidovudine (used to treat HIV) • any plasma protein binding medicines (e. g. lipoproteins or globulins).

Important information about some of the ingredients of Mefenamic Acid • Patients should note that Mefenamic Acid tablets contain Sunset Yellow (E110), which may cause allergic reactions.

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

3. HOW TO TAKE MEFENAMIC ACID

Pregnancy and breast-feeding • DO NOT take Mefenamic Acid during the final 3 months of pregnancy • If you are pregnant ask your doctor for advice before taking this medicine • DO NOT take Mefenamic Acid if you are breast-feeding • Mefenamic Acid may make it more difficult to become pregnant. You should speak to your doctor if you are planning to become pregnant or if you have problems becoming pregnant. Driving and using machines • Mefenamic Acid may make you feel drowsy, tired, or dizzy and affect your vision. DO NOT drive or operate machinery if you are affected.

Always take Mefenamic Acid exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. If you are taking Mefenamic Acid for a long period of time your doctor should be carefully monitoring you and regular blood tests may be carried out. If you are at higher risk of suffering from intestinal bleeding e. g. you are taking high doses or are elderly, your doctor may also give you another medicine to take at the same time to protect your stomach. Speak to your doctor immediately, if you start to suffer from loose stools soon after starting this medicine. If you see another doctor or go into hospital, let him or the staff know what medicines you are taking. The tablets should be swallowed with a drink of water, preferably with or after food. The usual dose is:

• serious illness with blistering of the skin, mouth, eyes and genitals. These are very serious but rare side effects. You may need urgent medical attention or hospitalisation.

MA Holder: TEVA UK Limited Eastbourne, BN22 9AG. PL 00289/0235 62230-V

If you forget to take Mefenamic Acid If you forget to take a tablet, take one as soon as you remember, unless it is nearly time to take the next one. DO NOT take a double dose to make up for a forgotten dose. Take the remaining doses at the correct time.

Each tablet contains 500 mg of mefenamic acid. Also contains E110. DOSAGE: Use as directed by the doctor. Please read the enclosed package leaflet before use. KEEP OUT OF THE REACH AND SIGHT OF CHILDREN Store below 25°C. Store in the original package.

An overdose is likely to cause headache, feeling sick, being sick, stomach pain, and rarely diarrhoea. Please take this leaflet, any remaining tablets, and the container with you to the hospital or doctor so that they know which tablets were consumed.

65 mm Page 8 • Adults 500 mg, three times a day. Excessive menstrual bleeding Mefenamic Acid should be taken on the first day of excessive bleeding. Menstrual pain Mefenamic Acid should be taken when the pain begins. In both of these conditions, treatment will be continued according to your doctor's instructions. • Elderly (over 65 years) Your doctor will start you on the lowest effective dose and may monitor you at the beginning of your treatment for stomach bleeding. • Children Mefenamic Acid tablets are not suitable for use in children. An alternative form of Mefenamic Acid should be used. If you take more Mefenamic Acid than you should If you (or someone else) swallow a lot of the tablets all together, or if you think a child has swallowed any of the tablets, contact your nearest hospital casualty department or your doctor immediately.

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Triderm - Fda Prescribing Information, Side Effects And Uses, Akriderm

Triderm

Triderm Description

The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. Triamcinolone acetonide is a member of this class. Triamcinolone acetonide is chemically pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis-(oxy)]-(11β, 16α)- with the empirical formula C 24 H 31 FO 6 and molecular weight 434.50. Its structural formula is:

Each gram of Triderm (Triamcinolone Acetonide Cream USP), 0.025% contains 0.25 mg triamcinolone acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

Each gram of Triderm (Triamcinolone Acetonide Cream USP), 0.1% contains 1 mg triamcinolone acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

Each gram of Triderm (Triamcinolone Acetonide Cream USP), 0.5% contains 5 mg triamcinolone acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

Triderm - Clinical Pharmacology

Topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.

Pharmacokinetics The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses. (See DOSAGE AND ADMINISTRATION ). Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.

Indications and Usage for Triderm

Triderm CREAM ® is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Contraindications

Triderm CREAM ® is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Precautions

General Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients. Conditions which augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids. Children may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity (See PRECAUTIONS-Pediatric use ). If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted. In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled.

Information for the Patient

Patients using topical corticosteroids should receive the following information and instructions: 1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes. 2. Patients should be advised not to use this medication for any disorder other than for which it was prescribed. 3. The treated skin area should not be bandaged or otherwise covered or wrapped as to be occlusive unless directed by the physician. 4. Patients should report any signs of local adverse reactions especially under occlusive dressing. 5. Parents of pediatric patients should be advised not to use tight-fitting diapers or plastic pants on a child being treated in the diaper area, as these garments may constitute occlusive dressings.

Laboratory Tests

The following tests may be helpful in evaluating the HPA axis suppression: Urinary free cortisol test ACTH stimulation test

Carcinogenesis, Mutagenesis, and Impairment of Fertility

Long-term animal studies have not been performed to evaluate the carcinogenic potential or the effect on fertility of topical corticosteroids. Studies to determine mutagenicity with prednisolone and hydrocortisone have revealed negative results.

Pregnancy Category C

Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Nursing Mothers

It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman.

Pediatric Use

Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing’s syndrome than mature patients because of a larger skin surface area to body weight ratio. Hypothalamic-pituitary-adrenaI (HPA) axis suppression, Cushing’s syndrome, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema. Administration of topical corticosteroids to children should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of children.

Adverse Reactions

The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Itching Irritation Dryness Folliculitis Hypertrichosis Acneiform eruptions Hypopigmentation Perioral dermatitis Allergic contact dermatitis Maceration of the skin Secondary infection Skin Atrophy Striae Miliaria

Overdosage

Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects. (See PRECAUTIONS )

Triderm Dosage and Administration

Topical corticosteroids are generally applied to the affected area as a thin film from two to three times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.

STORAGE

Store at 20 o - 25 o C (68 o - 77 o F) [see USP Controlled Room Temperature]

How is Triderm Supplied

Triderm ® (Triamcinolone Acetonide Cream USP), 0.025% is supplied in:

15 grams tube NDC 0316-0165-15

85.2 grams tube NDC 0316-0165-85

454 grams jar NDC 0316-0165-16

Triderm® (Triamcinolone Acetonide Cream USP), 0.1% is supplied in: 28.4 grams tube NDC 0316-0170-01

85.2 grams tube NDC 0316-0170-03

Triderm® (Triamcinolone Acetonide Cream USP), 0.5% is supplied in:

15 grams tube NDC 0316-0175-15

Manufactured and Distributed by Crown Laboratories, Inc. Johnson City, TN 37604

Revised: Feb 2015

PRINTED IN USA P8002.01

Triderm (Triamcinolone Acetonide Cream USP), 0.1% tube label

NDC 0316-0170-01 Triderm CREAM ®

Triamcinolone Acetonide Cream USP, 0.1%

Each gram contains 1 mg Triamcinolone Acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

Manufactured and Distributed by:

CROWN LABORATORIES, INC. Johnson City, TN 37604

Usual Dosage: 2 to 3 applications daily. See package insert for full prescribing information.

TO OPEN: Use cap to puncture seal.

IMPORTANT: Do not use if seal has been punctured or is not visible.

See Crimp of tube for Expiration Date and Batch Number. Store at 20 o -25 o C (68 o -77 o F) [see USP Controlled Room Temperature]. Avoid excessive heat. Protect from freezing.

For External Use Only. Not for Ophthalmic Use. WARNING: Keep Out Of Reach Of Children.

Triderm (Triamcinolone Acetonide Cream USP), 0.1% carton label

NDC 0316-0170-01 Triderm CREAM ® Triamcinolone Acetonide Cream USP, 0.1%

Each gram contains 1 mg Triamcinolone Acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

For External Use Only. Not for Ophthalmic Use. WARNING: Keep Out Of Reach Of Children.

Directions for puncturing tube seal: Remove cap. Turn cap upside down and place puncture tip onto tube seal: push down until seal is punctured.

Screw cap back on to close.

IMPORTANT: Do not use if seal has been punctured or is not visible.

Store at 20 o -25 o C (68 o -77 o F) [see USP Controlled Room Temperature]. Avoid excessive heat. Protect from freezing.

Manufactured and Distributed by: CROWN LABORATORIES, INC. Johnson City, TN 37604

Usual Dosage: 2 to 3 applications daily. See package insert for full prescribing information.

See end of carton for batch number and expiration date.

Triderm (Triamcinolone Acetonide Cream USP), 0.025% tube label

Triderm CREAM ®

Triamcinolone Acetonide Cream USP, 0.025%

For External Use Only Not for Ophthalmic Use

WARNING: Keep out of reach of children

Store at 20 o -25 o C (68 o -77 o F) [see USP Controlled Room Temperature]

Avoid excessive heat. Protect from freezing.

Each gram contains 0.25 mg triamcinolone acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

USUAL DOSAGE: 2 or 4 applications daily. See package insert for full prescribing information.

TO OPEN: Use cap to puncture seal.

IMPORTANT: Do not use if seal has been punctured or is not visible. See crimp of tube for batch number and expiration date.

Manufactured and Distributed by:

Crown Laboratories, Inc.

Johnson City, TN 37604

Triderm (Triamcinolone Acetonide Cream USP), 0.025% carton label

Triderm CREAM ®

Triamcinolone Acetonide Cream USP, 0.025%

For External Use Only Not for Ophthalmic Use

WARNING: Keep out of reach of children

USUAL DOSAGE: 2 or 4 applications daily. See package insert for full prescribing information.

See end of carton for batch number and expiration date.

Each gram contains 0.25 mg triamcinolone acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

Directions for puncturing seal: Remove cap. Turn cap upside down and place puncture tip onto tube seal; push down until seal is punctured. Screw cap back on to close

IMPORTANT: Do not use if seal has been punctured or is not visible.

Store at 20 o -25 o C (68 o -77 o F) [see USP Controlled Room Temperature]

Avoid excessive heat. Protect from freezing.

Manufactured and Distributed by: Crown Laboratories, Inc. Johnson City, TN 37604

Triderm (Triamcinolone Acetonide Cream USP), 0.5% tube label

Triderm CREAM ®

Triamcinolone Acetonide Cream USP, 0.5%

For External Use Only Not for Ophthalmic Use

WARNING: Keep out of reach of children

Store at 20 o -25 o C (68 o -77 o F) [see USP Controlled Room Temperature]

Avoid excessive heat. Protect from freezing.

Each gram contains 5 mg triamcinolone acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

USUAL DOSAGE: 2 or 3 applications daily. See package insert for full prescribing information.

TO OPEN: Use cap to puncture seal.

IMPORTANT: Do not use if seal has been punctured or is not visible. See crimp of tube for batch number and expiration date.

Manufactured and Distributed by:

Crown Laboratories, Inc.

Johnson City, TN 37604

Triderm (Triamcinolone Acetonide Cream USP), 0.5% carton label

Triderm CREAM ®

Triamcinolone Acetonide Cream USP, 0.5%

For External Use Only Not for Ophthalmic Use

WARNING: Keep out of reach of children

USUAL DOSAGE: 2 or 3 applications daily. See package insert for full prescribing information.

See end of carton for batch number and expiration date.

Each gram contains 5 mg triamcinolone acetonide USP in a cream base consisting of purified water, emulsifying wax, mineral oil, propylene glycol, sorbitol solution, cetyl palmitate, sorbic acid, and potassium sorbate.

Directions for puncturing seal: Remove cap. Turn cap upside down and place puncture tip onto tube seal; push down until seal is punctured. Screw cap back on to close

IMPORTANT: Do not use if seal has been punctured or is not visible.

Store at 20 o -25 o C (68 o -77 o F) [see USP Controlled Room Temperature]

Avoid excessive heat. Protect from freezing.

Manufactured and Distributed by: Crown Laboratories, Inc. Johnson City, TN 37604

Article Page, Phenytoinum

Phenytoin

John A. Davies

University of Wales College of Medicine, Cardiff, UK

Available online 8 January 2008.

Introduced as a treatment for all forms of …

Name of the Clinical Form Related Names Source: EMTREE

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Homepage - Office Of The New York City Comptroller Scott M, Comtro

MAKING THE GRADE

New York City Agency Report Card on Minority / Women-Owned Business Enterprises

New York City spends more than $14 billion on goods and services each year, but less than four percent goes toward Minority and Women-Owned Business Enterprises. The letter grades outlined in the “Making the Grade” report are intended as a diagnostic tool for City agencies to improve performance and transparency in M/WBE spending, increase competition in City procurement and save taxpayer dollars.

Red Tape Commission

Comptroller Stringer’s Red Tape Commission is made up of small business leaders, regulatory experts and advocates from around the City who are dedicated to finding ways to help business owners cut through the red tape. The Commission is grounded in the belief that government must be a partner, not an obstacle, to business owners.

A $15 Minimum Wage for New York City Food Service Workers

NYC Comptroller Scott M. Stringer released a report showing the economic benefits of raising the minimum wage for food service workers to $15 per-hour. Up to 180,000 workers could earn $1.3 billion more per year.

Take It To The Bank

Many New Yorkers do not have a bank account and rely on costly alternative financial services like check-cashing. Comptroller Scott M. Stringer released an online tool and report to empower consumers to find the most affordable bank for their needs.

The “Invisible Fare” Revealing NYC’s Full Contribution to the MTA

Comptroller Scott M. Stringer recently released a report showing New York City taxpayers and businesses pay a much greater portion of the operating and capital budgets for the Metropolitan Transportation Authority than previously known.

HOLES IN THE SAFETY NET: Obamacare and the Future of New York City’s Health & Hospitals Corporation

Comptroller Scott M. Stringer released the first public assessment of how planned cuts in federal funds for the care of the uninsured threatens the City's Health and Hospitals Corporation. The report also includes policy recommendations to expand access to affordable healthcare coverage for the uninsured, including undocumented immigrants.

AUDIT: Joint Announcement on the NYC Housing Authority Overhaul

New York City Comptroller Scott M. Stringer audit found serious weaknesses in how New York City Housing Authority (NYCHA) tracks, stores, and manages its inventory. In response, NYCHA Chair & CEO Shola Olatoye announced a complete overhaul of the agency's inventory system, including a working group to modernize its supply chain systems with input from the Comptroller's office and outside experts.

AUDIT: MTA Subway Cleaning & Painting

New York City Comptroller Scott M. Stringer released an audit of the Metropolitan Transportation Authority’s (MTA’s) New York City Transit showing that the vast majority of the City’s underground subway tracks are filled with garbage, dirt and other debris, a perfect home for rats and vermin and a fire hazard. Further, stations with peeling paint have been ignored and desperately need attention.

Dropping the Ball: Disparities in Physical Education in New York City Schools

Scott M. Stringer, New York City Comptroller, has released a interactive, school-by-school analysis showing that the New York City Department of Education is in violation of state physical education requirements and is failing to provide equal access to physical education resources.

AUDIT: NYC Express Buses

The MTA Bus and the New York City Transit transport up to 20 million New Yorkers per year on express buses. Comptroller Scott M. Stringer released an audit showing express buses lack reliability, transparent reporting, and consistent accessibility for the disabled.

AUDIT: Animal Care & Control Shelters

Comptroller Scott M. Stringer released an audit of Animal Care and Control of New York City. The key findings include: Improper drug storage, poor shelter conditions, and financial control weaknesses.

Income Analysis of a $15.00 Minimum Wage in New York City

New York City's minimum wage is the lowest of any major U. S. city - after adjusting for cost-of-living expenses. Comptroller Scott M. Stringer released projections showing that increasing the City minimum wage to $15 per hour could boost wages by $10 billion per year for nearly 1.5 million workers.

AUDIT: BUILD IT BACK PROGRAM

Private consultants were paid millions while Hurricane Sandy victims waited for relief to reconstruct their houses. Read the Comptroller's audit of the City's "Build it Back" Program designed to help homeowners rebuild their communities and the recommendations for improvement.

SAFEGUARDING OUR SAVINGS:

Protecting New Yorkers Through the Fiduciary Standard

Up to $17 billion are lost in personal retirement savings each year to hidden fees and conflicted advice from financial advisors. Read the Comptroller's report calling for a fiduciary standard to apply to all financial advisors.

TIME TO DELIVER:

Pregnancy and the Affordable Care Act

Pregnant women are put at risk when they can’t access health care. This report examines the negative health, financial, and societal risks associated with a lack of prenatal healthcare and how we can change laws to guarantee coverage.

IMMIGRANTS RIGHTS AND SERVICES MANUAL

A new, comprehensive guidebook for the NYC immigrant community to access City, state and federal services. The 70-page manual includes the real-life impacts of recent legislation and policy changes, such as the new municipal identification card and restrictions to the City’s cooperation with Immigration and Customs Enforcement (ICE).

The Boardroom Accountabilty Project

A national campaign to give shareowners a true voice in how corporate boards are elected at every U. S. company.

Pressing In To God, Pressin

"I press toward the mark for the prize of the high calling of God in Christ Jesus." (Philippians 3:14 KJV).

Much of our Christian life calls for a balance between extremes. One area where this is needed is the balance between striving and allowing God to act in our lives. In much of our Christian life, we work and God works. There are times when we can strive too hard. Sometimes we need to simply get out of the way and let God do what he wants to do. And we should never try to do in our own strength what only God can do in his strength.

But, as is so often the case, there is another side to Scripture, which says that there are also times when we need to put forth effort, sometimes quite strenuous effort, in order to receive the best that God has for us. In this paper I want to emphasize that side of the issue. I do this partly because we American Christians, living comfortable lives, sometimes need to be reminded of the need to struggle against apathy and self-satisfaction, and partly because I need it myself.

There are a large number of energetic verbs in the New Testament, which speak of the effort we may need to put forth. Most are in a tense that speaks of continuing effort. We find words like "make every effort", "strain", "struggle", "pursue", "run with diligence the race set before you", "fight the good fight", "wage war", "persist', "resist", "stand", "take hold", "guard", "endure to the end". I want to look at some of those concepts.

B. Taking the Kingdom of God by Force.

In Matthew 11:12 Jesus declared that "From the days of John the Baptist until now, the kingdom of heaven has been forcefully advancing, and forceful men lay hold of it." Luke 16:16 is similar. (Unless otherwise noted, all Scripture quotations are from the New International Version, and any emphasis is mine.)

What does this passage mean? First . In what sense could it be said that the Kingdom of God was advancing forcefully? The statement must have surprised the disciples. They were expecting a kingly Messiah who would advance by military force to drive out the Roman occupiers, and restore the kingdom of Israel to the glory it had in the days of King David. They were puzzled and confused by a Messiah who showed no sign of doing any such thing (see Acts 1:6).

But in the spiritual sense I think we can see that Jesus' coming to earth was a frontal assault on the kingdom of satan.

With the Fall of Adam, satan had become "the prince of this world" (John 12:31, 14:30). Paul calls him the "god of this age" (2 Corinthians 4:4; see also Ephesians 2:2; 1 John 5:19). When, in the wilderness, satan offered to give Jesus "all the kingdoms of the world and their splendor" if Jesus would bow down to him (Matthew 4:9-10), satan had the authority to make the offer.

The reason Jesus came on earth was "to destroy the devil's work" (1 John 3:8), "to destroy him who holds the power of death - that is the devil" (Hebrews 2:14). When Jesus brought God's kingdom to earth, there were now two kingdoms, existing side by side - "the dominion of darkness" and the kingdom of God (Colossians 1:13). There were "children of God" and "children of the devil" (1 John 3:10; see John 8:42-27).

Satan sensed this attack. He tempted Jesus. He tried many times to have him killed. Wherever Jesus went the demons manifested. They sensed the threat, for they cried out, "Have you come to destroy us?" Mark 1:24), "Have you come here to torture us before the appointed time?" (Matthew 8:29).

Shortly before his crucifixion Jesus declared, "Now the prince of this world will be driven out" (John 12:31). Paul declares that Jesus, "having disarmed the [evil] powers and authorities, he made a public spectacle of them, triumphing over them by the cross" (Colossians 2:15).

The victory is not yet complete, but it is clear that, in the spiritual world, the kingdom of God has advanced forcefully.

Second . what does it mean to say that "forceful men lay hold of it", or, as KJV puts it, "the violent take it by force"? A look at some examples in which people have pressed in vigorously to the kingdom of God may be helpful.

C. Examples of Pressing in to the Kingdom of God.

The Bible gives us a number of examples of pressing in, arising in many areas of Christian life. When we add them all together I suggest that they show that God wants us to pursue him, his gifts and his promises, with an intense passion.

a. Blind Bartimaeus.

As Jesus was passing by, a blind beggar named Bartimaeus was sitting by the roadside. "When he heard that it was Jesus of Nazareth, he began to shout, 'Jesus, Son of David, have mercy on me!' Many rebuked him and told him to be quiet, but he shouted all the more, 'Son of David, have mercy on me.'" Jesus stopped, called him, and he received his sight. Then Jesus commended him, saying, "Your faith has healed you" (Mark 10:46-52).

Bartimaeus wanted one thing with all his heart. He wanted to see. He let nothing stop him. "Many rebuked him and told him to be quiet" but he "shouted all the more." (Matthew 20:31 says "shouted all the louder".) We don't know how long this went on; it could have been for some time. He would not be kept from the healing he sought. When Jesus commended his faith, I believe Jesus was saying that he had shown his faith by his persistence in the face of obstacles. Our faith is demonstrated by action, and this blind beggar demonstrated his by strong, persistent action.

b. The woman with the issue of blood.

On another occasion, as Jesus was walking, " A large crowd followed and pressed around him." A woman, who had been "subject to bleeding for twelve years", pressed in, touched his cloak, and was healed. Jesus asked who had touched him, and she fell at his feet, "trembling with fear." Then Jesus said, "Your faith has healed you" (Mark 5:24-34).

This woman persisted in the face of a number of obstacles:

Women were not supposed to press in through a crowd of men.

She was ceremonially unclean, and it was unlawful for her to touch anyone who was clean.

She was probably weak after a twelve-year illness involving loss of blood.

She was afraid.

Her urgent need motivated her to overcome all these obstacles and receive the healing she desired. Again I believe that it was because she pressed in, in spite of heavy obstacles, that Jesus praised her faith.

c. The Canaanite woman.

A Canaanite woman from the region of Tyre and Sidon came to Jesus, "crying out, 'Lord, Son of David, have mercy on me! My daughter is suffering terribly from demon-possession.' Jesus did not answer a word. So his disciples came to him and urged him, 'Send her away, for she keeps crying out after us.' He answered, 'I was sent only to the lost sheep of Israel.' The woman came and knelt before him. 'Lord, help me!' she said. He replied, 'It is not right to take the children's bread and toss it to their dogs.' 'Yes, Lord' she said, 'but even the dogs eat the crumbs that fall from their masters' table.' Then Jesus answered, 'Woman, you have great faith! Your request is granted.' And her daughter was healed from that very hour" (Matthew 15:22-28).

Again, we can see great persistence in spite of seeming rejection. And again, Jesus saw her persistence, her pressing in, as evidence of "great faith."

d. The Paralytic.

Once there was a great crowd in the house where Jesus was. Some men came bringing a paralytic. "Since they could not get him to Jesus because of the crowd, they made an opening in the roof above Jesus and, after digging through it, lowered the mat the paralyzed man was lying on. When Jesus saw their faith, he said to the paralytic, 'Son, your sins are forgiven." Then he said to the paralytic, "'Get up, take your mat and go home.' He got up, took his mat and walked out in full view of them all" (Mark 2:3-5, 11-12).

The paralytic's friends pressed in. It seemed impossible to get their friend to Jesus, but they found a way. They had to lift him up onto the roof (while on his mat), make a hole in the roof, and then lower him down into the dense crowd. Jesus was impressed with their persistance in the face of seemingly insuperable obstacles. "When he saw their faith" he healed their friend.

"Jesus told his disciples a parable to show them that they should always pray and not give up" (Luke 18:1). The parable was that of the widow who kept insisting that the unjust judge give her justice. Jesus ended, "And will not God bring about justice for his chosen ones, who cry out to him day and night?" (Luke 18:7).

Earlier he had told another parable about a man who needed bread to give a visitor. He knocked at his neighbor's door at midnight to try borrow bread. The neighbor refused, saying he was in bed, but eventually yielded. Jesus said "Because of the man's boldness he will get up and give him as much as he needs" (Luke 11:8). (KJV has "importunity". The word can mean recklessness or shamelessness).

Then Jesus went on "So I say to you, Ask and it will be given to you; seek and you will find; knock and the door will be opened to you. For everyone who asks receives; he who seeks finds; and to him who knocks, the door will be opened" (Luke 11:9-10). The Greek verbs mean, "continue to ask", "continue to seek", "continue to knock". And it seems clear in context that Jesus is saying, "If you keep on asking, seeking, and knocking with the same persistence as was shown by the man in the parable, you will receive."

It is those who seek God "with all your heart" who will surely find him (Jeremiah 29:13). It is the "fervent" prayer of a righteous man that accomplishes much (James 5:16 KJV). Paul says that "the Spirit himself intercedes for us with groans that words cannot express" (Romans 8:26). Jesus says that it is right, and sometimes necessary, to "cry out" to God, day and night. All of these passages suggest that there needs to be an intensity and fervency in our prayers. There needs to be passion, and also persistency.

When Jesus was having dinner at the home of a Pharisee, "a woman who had led a sinful life" came in, wet his feet with her tears, dried them with her hair, kissed them, and poured perfume on them. The Pharisee said to himself, "If this man were a prophet, he would know who is touching him and what kind of woman she is - that she is a sinner". But Jesus received her worship and told her, "Your sins are forgiven" (Luke 7:36-50).

Not only did this woman come into the house uninvited, but she must have sensed the scorn and rejection in the face of the Pharisee and probably many of his guests. Pharisees would have nothing to do with "sinners", particularly with immoral women. Yet she persisted in her act of worship and service, and received a great blessing.

"Blessed are those who hunger and thirst for righteousness, for they will be filled" (Matthew 5:6). "Hunger" and "thirst" are words of desiring. They can mean a very intense desire. Strong says that the Greek word for "hunger" means "famish", from a related word meaning "starving". "Thirst" in the Near East, can often be an intense thirst. The form, in the Greek, is "the hungering ones," that is, those who keep hungering. I believe this Beatitude speaks of a continuing desire for God's righteousness that may be filled at one level only to break out again at another level, and is completely satisfied only in heaven.

Jacob wrestled with God all night. God lamed his hip but Jacob would not let go. Jacob said, "I will not let you go unless you bless me" (Genesis 32:26). Jacob persisted until he got his blessing.

We usually think of salvation as a free gift from God. All we have to do is to be willing to accept it. That is the way many of the Scriptures relating to salvation speak. But there is another thread in Scripture which calls for a vigorous effort on our part. We cannot win salvation, or earn it, by our effort, but sometimes we receive it only after a good deal of effort.

I believe Matthew 11:12 is talking about salvation. What does laying hold of the kingdom of God mean, if it does not include laying hold of the promise of salvation - a victorious life here on earth and eternal life in heaven? And Jesus says that it is forceful (or violent) men who lay hold of this salvation. But there is more.

a. Enter the narrow door.

"Someone asked him, 'Lord, are only a few people going to be saved?' He said to them, 'Make every effort to enter through the narrow door, because many, I tell you, will try to enter and will not be able to'" (Luke 13:23-24). (We know from Matthew 7:13-14 that the narrow gate or door leads to eternal life and the wide gate leads to destruction.) The verb "make every effort" (KJV "strive") is agonizomai . closely related to our word "agony." It means to struggle, to compete, to contend with an adversary, to contend for victory. It is in a continuing tense, "keep on striving".

b. Work out your salvation.

"Continue to work out your salvation with fear and trembling, for it is God who works in you to will and to act according to his good purposes" (Philippians 2:12). The verb "work out". katergazomia . is from ergazomai . to toil, labor, work (the root of our words "energy" and "erg" - a measure of work) and the prefix kata which, according to Strong, "frequently denotes opposition. or intensity." So we must toil or labor against opposition to complete our salvation. We do it "with fear and trembling"

c. The pearl of great price.

A different kind of intensity is expressed in one of Jesus' kingdom parables

"The kingdom of heaven is like a merchant looking for fine pearls. When he found one of great value, he went away and sold everything he had and bought it" (Matthew 13:45-46). The picture is of a man who has devoted his life to an intense search. When he finally finds what he is seeking, he sacrifices everything he has in order to get it. He is happy to make the sacrifice for his joy in what he is to receive (compare verse 44), but it still means a sacrifice. We see this in Philippians 3:5-11, where Paul, who was a "comer" with a very promising future before him as a Pharisee, gave it all up and considered it rubbish (KJV "dung") "for the surpassing greatness of knowing Christ Jesus my Lord, for whose sake I have lost all things."

Scripture talks a good deal about the cost of following Jesus. (See, for example, Luke 9:57-62). Most of the early disciples faced martyrdom. Many today, in Muslim and Communist countries, face severe persecution. Why are they willing to do so? Because they have such an intense desire for the kingdom of God!

6. Sanctification and growing to maturity.

Once we are saved we start the process of growing to Christian maturity. This process has a number of aspects. Each of them, at times, calls for us to put forth significant effort.

"Just as he who called you is holy, so be holy in all you do; for it is written, 'Be holy, because I am holy'" (1 Peter 1:15). "For God did not call us to be impure, but to live a holy life. Therefore he who rejects this instruction does not reject man but God, who gives you his Holy Spirit" (1 Thessalonians 4:7-8).

Being holy, or sanctification, is a necessary part of our Christian growth. Many Scriptures speak of this as something God does. (See, for example John 17:17; 1 Peter 1:2). But those quoted above speak of it as something we must decide to do and then do. "Make every effort to live in peace with all men and to be holy; without holiness no one will see the Lord" (Hebrews 12:14). Even though God does it, we also must "make every effort" to be holy.

b. Live by the spirit.

The way to become holy is to live by the Holy Spirit, to live a life controlled by the Holy Spirit. Scripture makes it clear that this is a choice we must make, and that it requires constant application on our part.

"Live by the Spirit, and you will not gratify the desires of the sinful nature" (Galatians 5:16). This is a choice we make. It is not an easy choice, for Paul says that the sinful nature and the Spirit "are in conflict with each other" (Galatians 5:17). The consequences of this choice are enormous. Those who live according to the sinful nature "will not inherit the kingdom of God" (Galatians 5:21). "A man reaps what he sows. The one who sows to please his sinful nature, from that nature will reap destruction; the one who sows to please the Spirit, from the Spirit will receive eternal life" (Galatians 6:7-8). Those who succeed in living by the Spirit receive and show the fruit of the spirit: "love, joy, peace, patience, kindness, goodness, faithfulness, gentleness and self-control" (Galatians 5:22-23).

Romans is similar. It speaks of an internal warfare, in which the fleshly nature is "waging war" against God's law (Romans 7:23; see also 1 Peter 2:11). It tells us to live a life "controlled by the Spirit" (Romans 8:6). It says, "If you live according to the sinful nature you will die; but if by the Spirit you put to death the misdeeds of the body you will live" (Romans 8:13).

I believe it is largely of this inner warfare that 2 Corinthians 10:3-5 is speaking when it says that the weapons of our warfare have divine power to "demolish strongholds", and to "take captive every thought to make it obedient to Christ."

We may have to take very strenuous measures to achieve victory in this warfare between the sinful nature and the Holy Spirit. "Put to death, therefore, whatever belongs to your earthly nature: sexual immorality, impurity, lust, evil desires and greed, which is idolatry. Because of these the wrath of God is coming" (Colossians 3:5-6; see Ephesians 5:6). Paul said "I die every day" (1 Corinthians 15:31). He also said, "I have been crucified with Christ and I no longer live, but Christ lives in me" (Galatians 2:20). We must "die to sins and live for righteousness" (1 Peter 2:24).

Jesus put it vividly. "If your hand causes you to sin, cut it off; it is better for you to enter life maimed than with two hands to go into hell, where the fire never goes out. And if your foot causes you to sin, cut it off. It is better for you to enter life crippled than to have two feet and be thrown into hell. And if your eye causes you to sin, pluck it out. It is better for you to enter the kingdom of God with one eye than to have two eyes and be thrown into hell, where 'their worm does not die, and the fire is not quenched'" (Mark 9:42-48). Jesus is using colorful imagery, but the point is clear. Whatever you have to do to get rid of the sinful nature, do it.

c. Be transformed.

"Therefore I urge you, brothers, in view of God's mercy, to offer your bodies as living sacrifices, holy and pleasing to God - this is your spiritual act of worship. Do not conform any longer to the pattern of this world, but be transformed by the renewing of your mind. Then you will be able to test and approve what God's will is - his good, pleasing and perfect will" (Romans 12:1-3).

Offering our bodies as living sacrifices requires decision and vigorous action on our part. This passage also commands us to be transformed. It speaks of a major change. The Greek word is metamorphoo . which speaks of a metamorphosis like that from a caterpillar to a butterfly.

How do we achieve this metamorphosis? In part it is by deliberately feeding our inner man with scripture, worship music, prayer, and sound teaching and preaching. By becoming filled with God's word and allowing it to work in us (see 1 Thessalonians 2:13). By allowing the word of God to be "engrafted" in us (James 1:21 KJV).

In part it is by recognizing every false belief and attitude, confronting it with the truth of God's word, and deciding to live by God's truth. This is part of the daily, even hourly or minute-by-minute, process of taking "captive every thought to make it obedient to Christ" (2 Corinthians 10:5). It is part of the process of throwing off "everything that hinders" (Hebrews 12:1). The goal of the transformation is to become like God in character (see my paper on "Be Transformed"). It takes determination and effort on our part.

d. Put on the new self.

Scripture refers to this transformation as putting off the old self and putting on the new self. a "new self created to be like God in true righteousness and holiness" (Ephesians 4:22-23), the "new self, which is being renewed in knowledge in the image of its Creator" (Colossians 3:9-10). This is a gradual process. It requires repeated decisions. "Which self am I being in this matter? Which self do I want to be?" It requires action.

Scripture repeatedly calls on us to grow, spiritually. "Grow up in your salvation" (1 Peter 2:2; see 2 Peter 3:18). Our goal, as Christians, is to be "built up", "to become mature", and to "grow up into Him who is the head, that is, Christ" (Ephesians 4:12-15). Paul prayed that we would be "growing in the knowledge of God, being strengthened with all power according to his glorious might so that you may have great endurance and patience" (Colossians 1:10-11). He prayed that Christ may give us "the Spirit of wisdom and revelation, so that you may know him better", and that "the eyes of your heart may be enlightened" in order that we may know "his incomparably great power for us who believe" (Ephesians 1:18-19). Paul commended the Thessalonians for living in order to please God, and then said, "Now we ask you and urge you in the Lord Jesus to do this more and more" (1 Thessalonians 4:1; see also 4:10). In whatever way we are living righteously, we need to keep doing it more and more.

Paul told Timothy to "exercise thyself. unto godliness" (1 Timothy 4:7 KJV). The Greek word is gymnazo . which refers to the intense training for athletic contests. We are to train like an athlete. Hebrews speaks of those "who by constant use have trained themselves to distinguish good from evil" (Hebrews 5:14). It speaks of God's discipline which "produces a harvest of righteousness and peace for those who have been trained by it" (Hebrews 12:11).

"His divine power has given us everything we need for life and godliness through our knowledge of him who called us by his own glory and goodness. Through these he has given us his very great and precious promises, so that through them you may participate in the divine nature and escape the corruption in the world caused by evil desires. For this very reason, make every effort to add to your faith goodness; and to goodness, knowledge; and to knowledge, self-control; and to self-control, perseverance; and to perseverance, godliness; and to godliness, brotherly kindness; and to brotherly kindness, love. For if you possess these qualities in increasing measure they will keep you from being ineffective and unproductive in your knowledge of our Lord Jesus Christ. Therefore, my brothers, be all the more eager to make your calling and election sure. For if you do these things you will never fail." (2 Peter 1:3-10).

I find this passage so revealing. God has given us everything we need. Therefore . we must make every effort, and pursue our calling and election eagerly. We cannot do anything without God. "Apart from me you can do nothing" (John 3:5). He has given us everything we need. "His incomparably great power" is at work in us (Ephesians 1:19; 3:20). We are "strong in the Lord and in his mighty power" (Ephesians 6:10). But at the same time, we must "make every effort" to possess certain qualities "in increasing measure." "From the one who has been entrusted with much, much more will be asked" (Luke 12:48). It is because he has given us so much that we must "make every effort."

f. Hold firmly to the word.

"By this gospel you are saved, if you hold firmly to the word I preached to you. Otherwise, you have believed in vain" (1 Corinthians 15:2). We are reconciled to God by Christ's death "if you continue in your faith, established and firm, not moved from the hope held out in the gospel" (Colossians 1:23; see also Colossians 2:6). "Stand firm and hold to the teachings we passed on to you" (2 Thessalonians 2:15). Paul wrote Timothy, "Watch your life and doctrine closely" (1 Timothy 4:16). "Guard the good deposit that was entrusted to you" (2 Timothy 1:14).

Jesus warned, "Watch out that no one deceives you" (Matthew 24:4). He warned against false teaching (Matthew 16:12) and false prophets (Matthew 7:15). Paul warned that in later times "some will abandon the faith and follow deceiving spirits and things taught by demons" (1 Timothy 4:1). He warned against being "blown here and there by every wind of teaching and by the cunning and craftiness of men in their deceitful scheming" (Ephesians 4:14). He speaks of those who have "wandered from the faith" (1 Timothy 6:21; 2 Timothy 2:18). Peter warns against "false teachers" who will "secretly introduce destructive heresies" and whom many will follow (2 Peter 2:1-2). He writes, "Be on your guard so that you may not be carried away by the error of lawless men and fall from your secure position" (2 Peter 3:17; see 2 John 8). John wrote, "Do not let anyone lead you astray" (1 John 3:7). Jude warns of false teachers and then says "build yourselves up in your most holy faith and pray in the Holy Spirit" (Jude 20).

Hebrews is full of warnings about falling away from true faith. "We must pay more careful attention, therefore, to what we have heard, so that we do not drift away" (Hebrews 2:2). "See to it, brothers, that none of you has a sinful, unbelieving heart that turns away from the living God" (Hebrews 3:17). "It is impossible for those who have once been enlightened. if they fall away, to be brought back to repentance" (Hebrews 6:4,6). "We want each of you to show this same diligence to the very end, in order to make your hope sure. We do not want you to become lazy, but to imitate those who through faith and patience inherit what has been promised" (Hebrews 6:11-12). "Let us hold unswervingly to the hope we profess" (Hebrews 10:23). "If we deliberately keep on sinning after we have received the knowledge of the truth, no sacrifice for sins is left, but only a fearful expectation of judgment and of raging fire that will consume the enemies of God" (Hebrews 10:26-27). "Do not throw away your confidence; it will be richly rewarded. You need to persevere, so that when you have done the will of God, you will receive what he has promised" (Hebrews 10:35-36). Do not "grow weary and lose heart" (Hebrews 12:3). "Strengthen your feeble arms and weak knees" (Hebrews 12:12). "See to it that no one misses the grace of God" (Hebrews 12:15). "See to it that you do not refuse him who speaks" (Hebrews 12:25). "Do not be carried away by all kinds of strange teachings" (Hebrews 13:9).

Our protection from falling away or being carried away lies in three things. (1) We must be alert: "Watch out." "Pay more careful attention". "Be on your guard". (2). We must consciously fill ourselves with true teaching: "Build yourselves up in your most holy faith." (3). We must hold to the truth: "Hold firmly." "Hold unswervingly." "Continue in your faith."

g. Trial and testing.

"Consider it pure joy, my brothers, whenever you face trials of many kinds, because you know that the testing of your faith develops perseverance. Perseverance must finish its work, so that you may be mature and complete, not lacking anything" (James 1:2-4). Romans 5:3-5; 1 Peter 1:6-7; and Hebrews 12:7-11 are similar. (Note that James assumes that trials will come. He says "whenever", not "if".)

God allows, and sometimes brings on us, trials, testings and difficulties of various kinds in order both to test and to strengthen our character. We can learn from them and grow from them. But while the process is going on, it may seem very strenuous and almost beyond our ability to cope with.

A key word is "perseverance". It is by persevering that the good soil produces a crop (Luke 8:15). It is by perseverance that we grow to maturity. Zodhiates says that "perseverance" "refers to the quality that does not surrender to circumstances or succumb under trial". (Spiros Zodhiates (ed.), Hebrew-Greek Key Word Study Bible, AMG International, 1991, p. 1765, #5281). Perseverance is an essential quality in Christian life.

h. Spiritual warfare.

Whether we like it or not, all committed Christians are engaged in spiritual warfare (Ephesians 6:10-18; 2 Corinthians 10:3-5). Warfare is strenuous. Scripture uses strenuous words to describe it. "Submit yourselves, then, to God. Resist the devil, and he will flee from you" (James 4:7). "Resist him [the devil], standing firm in the faith" (1 Peter 5:6). "Put on the full armor of God, so that when the evil day comes, you may be able to stand your ground, and after you have done everything, to stand" (Ephesians 6:13). We "struggle" (KJV "wrestle") against evil powers (Ephesians 6:12). We "wage war" (2 Corinthians 10:3). This is, indeed, a description of forceful or violent men.

7. The whole Christian life.

Let me close this section with two Scriptural descriptions of our whole Christian life which emphasize its energetic character.

"Let us throw off everything that hinders and the sin that so easily entangles, and let us run with perseverance the race marked out for us" (Hebrews 12:1). "Throw off", "run with perseverance". These are vigorous words.

Paul wrote, "One thing I do: Forgetting what is behind and straining toward what is ahead, I press on toward the goal to win the prize for which God has called me heavenward in Jesus Christ" (Philippians 3:13-14). If Paul felt it necessary to "strain" and "press on," can we afford to do less?

D. Why do we need to strive?

Why do we need to strive, to be forceful?

Let me suggest a few reasons:

Sometimes God wants to be sure that we are serious, that we mean business with him. Jesus had many followers. Only a few of them became disciples, and it was to the disciples that he devoted most of his training effort. Do we seek salvation just as an insurance policy against eternal damnation, or do we genuinely seek to accept the Lordship of Jesus Christ and serve him?

God is primarily interested in developing our character. Often the best way to develop character is to have to struggle against obstacles.

When we accept Jesus Christ as our Lord and Savior, and allow the Holy Spirit to enter into us, there inevitably begins a struggle, a warfare, between the old self and the new self, between the desires of the flesh and the Holy Spirit. That struggle is not resolved until the Holy Spirit has won complete control over our soul and body.

There is an enemy who seeks to kill, steal and destroy. If he cannot prevent us from being saved, he will seek to lead us into falsehood so that we will do his work. If he cannot do that he will seek to shut us down and make us ineffective. We need constantly to struggle against him.

God does not want lukewarm Christians (Revelation 3:16). He wants men and women who will love him "with all your heart and with all your soul and with all your mind and with all your strength (Mark 12:30). It is those who seek him "with all your heart" who find him (Jeremiah 29:13). He wants total commitment.

In these difficult days I believe God wants to raise up Christians to a new level of intensity. I think this will occur only if we cry out for it, if we seek it with everything in us, if we hunger and thirst for it.

But we need to remember that in our striving we strive with his mighty power, not our power. "Be strong in the Lord and in his mighty power" (Ephesians 6:10). We need to know "his incomparably great power for us who believe" (Ephesians 1:19). When we rely on his mighty power, we can, indeed, be "more than conquerors" (Romans 8:37).

"I press toward the mark for the prize of the high calling of God in Christ Jesus." (Philippians 3:14 KJV).

Much of our Christian life calls for a balance between extremes. One area where this is needed is the balance between striving and allowing God to act in our lives. In much of our Christian life, we work and God works. There are times when we can strive too hard. Sometimes we need to simply get out of the way and let God do what he wants to do. And we should never try to do in our own strength what only God can do in his strength.

But, as is so often the case, there is another side to Scripture, which says that there are also times when we need to put forth effort, sometimes quite strenuous effort, in order to receive the best that God has for us. In this paper I want to emphasize that side of the issue. I do this partly because we American Christians, living comfortable lives, sometimes need to be reminded of the need to struggle against apathy and self-satisfaction, and partly because I need it myself.

There are a large number of energetic verbs in the New Testament, which speak of the effort we may need to put forth. Most are in a tense that speaks of continuing effort. We find words like "make every effort", "strain", "struggle", "pursue", "run with diligence the race set before you", "fight the good fight", "wage war", "persist', "resist", "stand", "take hold", "guard", "endure to the end". I want to look at some of those concepts.

B. Taking the Kingdom of God by Force.

In Matthew 11:12 Jesus declared that "From the days of John the Baptist until now, the kingdom of heaven has been forcefully advancing, and forceful men lay hold of it." Luke 16:16 is similar. (Unless otherwise noted, all Scripture quotations are from the New International Version, and any emphasis is mine.)

What does this passage mean? First . In what sense could it be said that the Kingdom of God was advancing forcefully? The statement must have surprised the disciples. They were expecting a kingly Messiah who would advance by military force to drive out the Roman occupiers, and restore the kingdom of Israel to the glory it had in the days of King David. They were puzzled and confused by a Messiah who showed no sign of doing any such thing (see Acts 1:6).

But in the spiritual sense I think we can see that Jesus' coming to earth was a frontal assault on the kingdom of satan.

With the Fall of Adam, satan had become "the prince of this world" (John 12:31, 14:30). Paul calls him the "god of this age" (2 Corinthians 4:4; see also Ephesians 2:2; 1 John 5:19). When, in the wilderness, satan offered to give Jesus "all the kingdoms of the world and their splendor" if Jesus would bow down to him (Matthew 4:9-10), satan had the authority to make the offer.

The reason Jesus came on earth was "to destroy the devil's work" (1 John 3:8), "to destroy him who holds the power of death - that is the devil" (Hebrews 2:14). When Jesus brought God's kingdom to earth, there were now two kingdoms, existing side by side - "the dominion of darkness" and the kingdom of God (Colossians 1:13). There were "children of God" and "children of the devil" (1 John 3:10; see John 8:42-27).

Satan sensed this attack. He tempted Jesus. He tried many times to have him killed. Wherever Jesus went the demons manifested. They sensed the threat, for they cried out, "Have you come to destroy us?" Mark 1:24), "Have you come here to torture us before the appointed time?" (Matthew 8:29).

Shortly before his crucifixion Jesus declared, "Now the prince of this world will be driven out" (John 12:31). Paul declares that Jesus, "having disarmed the [evil] powers and authorities, he made a public spectacle of them, triumphing over them by the cross" (Colossians 2:15).

The victory is not yet complete, but it is clear that, in the spiritual world, the kingdom of God has advanced forcefully.

Second . what does it mean to say that "forceful men lay hold of it", or, as KJV puts it, "the violent take it by force"? A look at some examples in which people have pressed in vigorously to the kingdom of God may be helpful.

C. Examples of Pressing in to the Kingdom of God.

The Bible gives us a number of examples of pressing in, arising in many areas of Christian life. When we add them all together I suggest that they show that God wants us to pursue him, his gifts and his promises, with an intense passion.

a. Blind Bartimaeus.

As Jesus was passing by, a blind beggar named Bartimaeus was sitting by the roadside. "When he heard that it was Jesus of Nazareth, he began to shout, 'Jesus, Son of David, have mercy on me!' Many rebuked him and told him to be quiet, but he shouted all the more, 'Son of David, have mercy on me.'" Jesus stopped, called him, and he received his sight. Then Jesus commended him, saying, "Your faith has healed you" (Mark 10:46-52).

Bartimaeus wanted one thing with all his heart. He wanted to see. He let nothing stop him. "Many rebuked him and told him to be quiet" but he "shouted all the more." (Matthew 20:31 says "shouted all the louder".) We don't know how long this went on; it could have been for some time. He would not be kept from the healing he sought. When Jesus commended his faith, I believe Jesus was saying that he had shown his faith by his persistence in the face of obstacles. Our faith is demonstrated by action, and this blind beggar demonstrated his by strong, persistent action.

b. The woman with the issue of blood.

On another occasion, as Jesus was walking, " A large crowd followed and pressed around him." A woman, who had been "subject to bleeding for twelve years", pressed in, touched his cloak, and was healed. Jesus asked who had touched him, and she fell at his feet, "trembling with fear." Then Jesus said, "Your faith has healed you" (Mark 5:24-34).

This woman persisted in the face of a number of obstacles:

Women were not supposed to press in through a crowd of men.

She was ceremonially unclean, and it was unlawful for her to touch anyone who was clean.

She was probably weak after a twelve-year illness involving loss of blood.

She was afraid.

Her urgent need motivated her to overcome all these obstacles and receive the healing she desired. Again I believe that it was because she pressed in, in spite of heavy obstacles, that Jesus praised her faith.

c. The Canaanite woman.

A Canaanite woman from the region of Tyre and Sidon came to Jesus, "crying out, 'Lord, Son of David, have mercy on me! My daughter is suffering terribly from demon-possession.' Jesus did not answer a word. So his disciples came to him and urged him, 'Send her away, for she keeps crying out after us.' He answered, 'I was sent only to the lost sheep of Israel.' The woman came and knelt before him. 'Lord, help me!' she said. He replied, 'It is not right to take the children's bread and toss it to their dogs.' 'Yes, Lord' she said, 'but even the dogs eat the crumbs that fall from their masters' table.' Then Jesus answered, 'Woman, you have great faith! Your request is granted.' And her daughter was healed from that very hour" (Matthew 15:22-28).

Again, we can see great persistence in spite of seeming rejection. And again, Jesus saw her persistence, her pressing in, as evidence of "great faith."

d. The Paralytic.

Once there was a great crowd in the house where Jesus was. Some men came bringing a paralytic. "Since they could not get him to Jesus because of the crowd, they made an opening in the roof above Jesus and, after digging through it, lowered the mat the paralyzed man was lying on. When Jesus saw their faith, he said to the paralytic, 'Son, your sins are forgiven." Then he said to the paralytic, "'Get up, take your mat and go home.' He got up, took his mat and walked out in full view of them all" (Mark 2:3-5, 11-12).

The paralytic's friends pressed in. It seemed impossible to get their friend to Jesus, but they found a way. They had to lift him up onto the roof (while on his mat), make a hole in the roof, and then lower him down into the dense crowd. Jesus was impressed with their persistance in the face of seemingly insuperable obstacles. "When he saw their faith" he healed their friend.

"Jesus told his disciples a parable to show them that they should always pray and not give up" (Luke 18:1). The parable was that of the widow who kept insisting that the unjust judge give her justice. Jesus ended, "And will not God bring about justice for his chosen ones, who cry out to him day and night?" (Luke 18:7).

Earlier he had told another parable about a man who needed bread to give a visitor. He knocked at his neighbor's door at midnight to try borrow bread. The neighbor refused, saying he was in bed, but eventually yielded. Jesus said "Because of the man's boldness he will get up and give him as much as he needs" (Luke 11:8). (KJV has "importunity". The word can mean recklessness or shamelessness).

Then Jesus went on "So I say to you, Ask and it will be given to you; seek and you will find; knock and the door will be opened to you. For everyone who asks receives; he who seeks finds; and to him who knocks, the door will be opened" (Luke 11:9-10). The Greek verbs mean, "continue to ask", "continue to seek", "continue to knock". And it seems clear in context that Jesus is saying, "If you keep on asking, seeking, and knocking with the same persistence as was shown by the man in the parable, you will receive."

It is those who seek God "with all your heart" who will surely find him (Jeremiah 29:13). It is the "fervent" prayer of a righteous man that accomplishes much (James 5:16 KJV). Paul says that "the Spirit himself intercedes for us with groans that words cannot express" (Romans 8:26). Jesus says that it is right, and sometimes necessary, to "cry out" to God, day and night. All of these passages suggest that there needs to be an intensity and fervency in our prayers. There needs to be passion, and also persistency.

When Jesus was having dinner at the home of a Pharisee, "a woman who had led a sinful life" came in, wet his feet with her tears, dried them with her hair, kissed them, and poured perfume on them. The Pharisee said to himself, "If this man were a prophet, he would know who is touching him and what kind of woman she is - that she is a sinner". But Jesus received her worship and told her, "Your sins are forgiven" (Luke 7:36-50).

Not only did this woman come into the house uninvited, but she must have sensed the scorn and rejection in the face of the Pharisee and probably many of his guests. Pharisees would have nothing to do with "sinners", particularly with immoral women. Yet she persisted in her act of worship and service, and received a great blessing.

"Blessed are those who hunger and thirst for righteousness, for they will be filled" (Matthew 5:6). "Hunger" and "thirst" are words of desiring. They can mean a very intense desire. Strong says that the Greek word for "hunger" means "famish", from a related word meaning "starving". "Thirst" in the Near East, can often be an intense thirst. The form, in the Greek, is "the hungering ones," that is, those who keep hungering. I believe this Beatitude speaks of a continuing desire for God's righteousness that may be filled at one level only to break out again at another level, and is completely satisfied only in heaven.

Jacob wrestled with God all night. God lamed his hip but Jacob would not let go. Jacob said, "I will not let you go unless you bless me" (Genesis 32:26). Jacob persisted until he got his blessing.

We usually think of salvation as a free gift from God. All we have to do is to be willing to accept it. That is the way many of the Scriptures relating to salvation speak. But there is another thread in Scripture which calls for a vigorous effort on our part. We cannot win salvation, or earn it, by our effort, but sometimes we receive it only after a good deal of effort.

I believe Matthew 11:12 is talking about salvation. What does laying hold of the kingdom of God mean, if it does not include laying hold of the promise of salvation - a victorious life here on earth and eternal life in heaven? And Jesus says that it is forceful (or violent) men who lay hold of this salvation. But there is more.

a. Enter the narrow door.

"Someone asked him, 'Lord, are only a few people going to be saved?' He said to them, 'Make every effort to enter through the narrow door, because many, I tell you, will try to enter and will not be able to'" (Luke 13:23-24). (We know from Matthew 7:13-14 that the narrow gate or door leads to eternal life and the wide gate leads to destruction.) The verb "make every effort" (KJV "strive") is agonizomai . closely related to our word "agony." It means to struggle, to compete, to contend with an adversary, to contend for victory. It is in a continuing tense, "keep on striving".

b. Work out your salvation.

"Continue to work out your salvation with fear and trembling, for it is God who works in you to will and to act according to his good purposes" (Philippians 2:12). The verb "work out". katergazomia . is from ergazomai . to toil, labor, work (the root of our words "energy" and "erg" - a measure of work) and the prefix kata which, according to Strong, "frequently denotes opposition. or intensity." So we must toil or labor against opposition to complete our salvation. We do it "with fear and trembling"

c. The pearl of great price.

A different kind of intensity is expressed in one of Jesus' kingdom parables

"The kingdom of heaven is like a merchant looking for fine pearls. When he found one of great value, he went away and sold everything he had and bought it" (Matthew 13:45-46). The picture is of a man who has devoted his life to an intense search. When he finally finds what he is seeking, he sacrifices everything he has in order to get it. He is happy to make the sacrifice for his joy in what he is to receive (compare verse 44), but it still means a sacrifice. We see this in Philippians 3:5-11, where Paul, who was a "comer" with a very promising future before him as a Pharisee, gave it all up and considered it rubbish (KJV "dung") "for the surpassing greatness of knowing Christ Jesus my Lord, for whose sake I have lost all things."

Scripture talks a good deal about the cost of following Jesus. (See, for example, Luke 9:57-62). Most of the early disciples faced martyrdom. Many today, in Muslim and Communist countries, face severe persecution. Why are they willing to do so? Because they have such an intense desire for the kingdom of God!

6. Sanctification and growing to maturity.

Once we are saved we start the process of growing to Christian maturity. This process has a number of aspects. Each of them, at times, calls for us to put forth significant effort.

"Just as he who called you is holy, so be holy in all you do; for it is written, 'Be holy, because I am holy'" (1 Peter 1:15). "For God did not call us to be impure, but to live a holy life. Therefore he who rejects this instruction does not reject man but God, who gives you his Holy Spirit" (1 Thessalonians 4:7-8).

Being holy, or sanctification, is a necessary part of our Christian growth. Many Scriptures speak of this as something God does. (See, for example John 17:17; 1 Peter 1:2). But those quoted above speak of it as something we must decide to do and then do. "Make every effort to live in peace with all men and to be holy; without holiness no one will see the Lord" (Hebrews 12:14). Even though God does it, we also must "make every effort" to be holy.

b. Live by the spirit.

The way to become holy is to live by the Holy Spirit, to live a life controlled by the Holy Spirit. Scripture makes it clear that this is a choice we must make, and that it requires constant application on our part.

"Live by the Spirit, and you will not gratify the desires of the sinful nature" (Galatians 5:16). This is a choice we make. It is not an easy choice, for Paul says that the sinful nature and the Spirit "are in conflict with each other" (Galatians 5:17). The consequences of this choice are enormous. Those who live according to the sinful nature "will not inherit the kingdom of God" (Galatians 5:21). "A man reaps what he sows. The one who sows to please his sinful nature, from that nature will reap destruction; the one who sows to please the Spirit, from the Spirit will receive eternal life" (Galatians 6:7-8). Those who succeed in living by the Spirit receive and show the fruit of the spirit: "love, joy, peace, patience, kindness, goodness, faithfulness, gentleness and self-control" (Galatians 5:22-23).

Romans is similar. It speaks of an internal warfare, in which the fleshly nature is "waging war" against God's law (Romans 7:23; see also 1 Peter 2:11). It tells us to live a life "controlled by the Spirit" (Romans 8:6). It says, "If you live according to the sinful nature you will die; but if by the Spirit you put to death the misdeeds of the body you will live" (Romans 8:13).

I believe it is largely of this inner warfare that 2 Corinthians 10:3-5 is speaking when it says that the weapons of our warfare have divine power to "demolish strongholds", and to "take captive every thought to make it obedient to Christ."

We may have to take very strenuous measures to achieve victory in this warfare between the sinful nature and the Holy Spirit. "Put to death, therefore, whatever belongs to your earthly nature: sexual immorality, impurity, lust, evil desires and greed, which is idolatry. Because of these the wrath of God is coming" (Colossians 3:5-6; see Ephesians 5:6). Paul said "I die every day" (1 Corinthians 15:31). He also said, "I have been crucified with Christ and I no longer live, but Christ lives in me" (Galatians 2:20). We must "die to sins and live for righteousness" (1 Peter 2:24).

Jesus put it vividly. "If your hand causes you to sin, cut it off; it is better for you to enter life maimed than with two hands to go into hell, where the fire never goes out. And if your foot causes you to sin, cut it off. It is better for you to enter life crippled than to have two feet and be thrown into hell. And if your eye causes you to sin, pluck it out. It is better for you to enter the kingdom of God with one eye than to have two eyes and be thrown into hell, where 'their worm does not die, and the fire is not quenched'" (Mark 9:42-48). Jesus is using colorful imagery, but the point is clear. Whatever you have to do to get rid of the sinful nature, do it.

c. Be transformed.

"Therefore I urge you, brothers, in view of God's mercy, to offer your bodies as living sacrifices, holy and pleasing to God - this is your spiritual act of worship. Do not conform any longer to the pattern of this world, but be transformed by the renewing of your mind. Then you will be able to test and approve what God's will is - his good, pleasing and perfect will" (Romans 12:1-3).

Offering our bodies as living sacrifices requires decision and vigorous action on our part. This passage also commands us to be transformed. It speaks of a major change. The Greek word is metamorphoo . which speaks of a metamorphosis like that from a caterpillar to a butterfly.

How do we achieve this metamorphosis? In part it is by deliberately feeding our inner man with scripture, worship music, prayer, and sound teaching and preaching. By becoming filled with God's word and allowing it to work in us (see 1 Thessalonians 2:13). By allowing the word of God to be "engrafted" in us (James 1:21 KJV).

In part it is by recognizing every false belief and attitude, confronting it with the truth of God's word, and deciding to live by God's truth. This is part of the daily, even hourly or minute-by-minute, process of taking "captive every thought to make it obedient to Christ" (2 Corinthians 10:5). It is part of the process of throwing off "everything that hinders" (Hebrews 12:1). The goal of the transformation is to become like God in character (see my paper on "Be Transformed"). It takes determination and effort on our part.

d. Put on the new self.

Scripture refers to this transformation as putting off the old self and putting on the new self. a "new self created to be like God in true righteousness and holiness" (Ephesians 4:22-23), the "new self, which is being renewed in knowledge in the image of its Creator" (Colossians 3:9-10). This is a gradual process. It requires repeated decisions. "Which self am I being in this matter? Which self do I want to be?" It requires action.

Scripture repeatedly calls on us to grow, spiritually. "Grow up in your salvation" (1 Peter 2:2; see 2 Peter 3:18). Our goal, as Christians, is to be "built up", "to become mature", and to "grow up into Him who is the head, that is, Christ" (Ephesians 4:12-15). Paul prayed that we would be "growing in the knowledge of God, being strengthened with all power according to his glorious might so that you may have great endurance and patience" (Colossians 1:10-11). He prayed that Christ may give us "the Spirit of wisdom and revelation, so that you may know him better", and that "the eyes of your heart may be enlightened" in order that we may know "his incomparably great power for us who believe" (Ephesians 1:18-19). Paul commended the Thessalonians for living in order to please God, and then said, "Now we ask you and urge you in the Lord Jesus to do this more and more" (1 Thessalonians 4:1; see also 4:10). In whatever way we are living righteously, we need to keep doing it more and more.

Paul told Timothy to "exercise thyself. unto godliness" (1 Timothy 4:7 KJV). The Greek word is gymnazo . which refers to the intense training for athletic contests. We are to train like an athlete. Hebrews speaks of those "who by constant use have trained themselves to distinguish good from evil" (Hebrews 5:14). It speaks of God's discipline which "produces a harvest of righteousness and peace for those who have been trained by it" (Hebrews 12:11).

"His divine power has given us everything we need for life and godliness through our knowledge of him who called us by his own glory and goodness. Through these he has given us his very great and precious promises, so that through them you may participate in the divine nature and escape the corruption in the world caused by evil desires. For this very reason, make every effort to add to your faith goodness; and to goodness, knowledge; and to knowledge, self-control; and to self-control, perseverance; and to perseverance, godliness; and to godliness, brotherly kindness; and to brotherly kindness, love. For if you possess these qualities in increasing measure they will keep you from being ineffective and unproductive in your knowledge of our Lord Jesus Christ. Therefore, my brothers, be all the more eager to make your calling and election sure. For if you do these things you will never fail." (2 Peter 1:3-10).

I find this passage so revealing. God has given us everything we need. Therefore . we must make every effort, and pursue our calling and election eagerly. We cannot do anything without God. "Apart from me you can do nothing" (John 3:5). He has given us everything we need. "His incomparably great power" is at work in us (Ephesians 1:19; 3:20). We are "strong in the Lord and in his mighty power" (Ephesians 6:10). But at the same time, we must "make every effort" to possess certain qualities "in increasing measure." "From the one who has been entrusted with much, much more will be asked" (Luke 12:48). It is because he has given us so much that we must "make every effort."

f. Hold firmly to the word.

"By this gospel you are saved, if you hold firmly to the word I preached to you. Otherwise, you have believed in vain" (1 Corinthians 15:2). We are reconciled to God by Christ's death "if you continue in your faith, established and firm, not moved from the hope held out in the gospel" (Colossians 1:23; see also Colossians 2:6). "Stand firm and hold to the teachings we passed on to you" (2 Thessalonians 2:15). Paul wrote Timothy, "Watch your life and doctrine closely" (1 Timothy 4:16). "Guard the good deposit that was entrusted to you" (2 Timothy 1:14).

Jesus warned, "Watch out that no one deceives you" (Matthew 24:4). He warned against false teaching (Matthew 16:12) and false prophets (Matthew 7:15). Paul warned that in later times "some will abandon the faith and follow deceiving spirits and things taught by demons" (1 Timothy 4:1). He warned against being "blown here and there by every wind of teaching and by the cunning and craftiness of men in their deceitful scheming" (Ephesians 4:14). He speaks of those who have "wandered from the faith" (1 Timothy 6:21; 2 Timothy 2:18). Peter warns against "false teachers" who will "secretly introduce destructive heresies" and whom many will follow (2 Peter 2:1-2). He writes, "Be on your guard so that you may not be carried away by the error of lawless men and fall from your secure position" (2 Peter 3:17; see 2 John 8). John wrote, "Do not let anyone lead you astray" (1 John 3:7). Jude warns of false teachers and then says "build yourselves up in your most holy faith and pray in the Holy Spirit" (Jude 20).

Hebrews is full of warnings about falling away from true faith. "We must pay more careful attention, therefore, to what we have heard, so that we do not drift away" (Hebrews 2:2). "See to it, brothers, that none of you has a sinful, unbelieving heart that turns away from the living God" (Hebrews 3:17). "It is impossible for those who have once been enlightened. if they fall away, to be brought back to repentance" (Hebrews 6:4,6). "We want each of you to show this same diligence to the very end, in order to make your hope sure. We do not want you to become lazy, but to imitate those who through faith and patience inherit what has been promised" (Hebrews 6:11-12). "Let us hold unswervingly to the hope we profess" (Hebrews 10:23). "If we deliberately keep on sinning after we have received the knowledge of the truth, no sacrifice for sins is left, but only a fearful expectation of judgment and of raging fire that will consume the enemies of God" (Hebrews 10:26-27). "Do not throw away your confidence; it will be richly rewarded. You need to persevere, so that when you have done the will of God, you will receive what he has promised" (Hebrews 10:35-36). Do not "grow weary and lose heart" (Hebrews 12:3). "Strengthen your feeble arms and weak knees" (Hebrews 12:12). "See to it that no one misses the grace of God" (Hebrews 12:15). "See to it that you do not refuse him who speaks" (Hebrews 12:25). "Do not be carried away by all kinds of strange teachings" (Hebrews 13:9).

Our protection from falling away or being carried away lies in three things. (1) We must be alert: "Watch out." "Pay more careful attention". "Be on your guard". (2). We must consciously fill ourselves with true teaching: "Build yourselves up in your most holy faith." (3). We must hold to the truth: "Hold firmly." "Hold unswervingly." "Continue in your faith."

g. Trial and testing.

"Consider it pure joy, my brothers, whenever you face trials of many kinds, because you know that the testing of your faith develops perseverance. Perseverance must finish its work, so that you may be mature and complete, not lacking anything" (James 1:2-4). Romans 5:3-5; 1 Peter 1:6-7; and Hebrews 12:7-11 are similar. (Note that James assumes that trials will come. He says "whenever", not "if".)

God allows, and sometimes brings on us, trials, testings and difficulties of various kinds in order both to test and to strengthen our character. We can learn from them and grow from them. But while the process is going on, it may seem very strenuous and almost beyond our ability to cope with.

A key word is "perseverance". It is by persevering that the good soil produces a crop (Luke 8:15). It is by perseverance that we grow to maturity. Zodhiates says that "perseverance" "refers to the quality that does not surrender to circumstances or succumb under trial". (Spiros Zodhiates (ed.), Hebrew-Greek Key Word Study Bible, AMG International, 1991, p. 1765, #5281). Perseverance is an essential quality in Christian life.

h. Spiritual warfare.

Whether we like it or not, all committed Christians are engaged in spiritual warfare (Ephesians 6:10-18; 2 Corinthians 10:3-5). Warfare is strenuous. Scripture uses strenuous words to describe it. "Submit yourselves, then, to God. Resist the devil, and he will flee from you" (James 4:7). "Resist him [the devil], standing firm in the faith" (1 Peter 5:6). "Put on the full armor of God, so that when the evil day comes, you may be able to stand your ground, and after you have done everything, to stand" (Ephesians 6:13). We "struggle" (KJV "wrestle") against evil powers (Ephesians 6:12). We "wage war" (2 Corinthians 10:3). This is, indeed, a description of forceful or violent men.

7. The whole Christian life.

Let me close this section with two Scriptural descriptions of our whole Christian life which

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Comprar Ispidon (Risperdal) Sin Receta, Ispidon

compra Ispidon (Risperdal) en linea sin receta

Ispidon (Risperdal) Explicacion

Ispidon se encuentra a traves de expertos de las drogas con el fin de luchar contra los problemas psicologicos (trastorno bipolar, odio, la esquizofrenia, asi como para los enfermos de mas edad 5-16 junto con el autismo). Concentrese en asociado con Ispidon seria para administrar a permanecer estabilidad del cerebro. Obras Ispidon proporcionando mentes estabilidad, asi como el equilibrio psicologico.

Ispidon es en realidad antipsicotico atipico.

Ispidon tambien puede ser referido como risperidona, Risdone.

titulo general asociada con Ispidon es en realidad risperidona.

Marcas asociadas con Ispidon tienden a ser Ispidon, Ispidon Consta, Ispidon M-Tab.

Ispidon (Risperdal) Dosis

Ispidon viene en:

1mg Baja Dosis material de friccion

material de friccion dosis regular 2mg

3 mg Mejora Dosis material de friccion

material de friccion 4mg Maxima Dosis

Ispidon viene en pastillas (1 miligramos, dos miligramos, tres, cuatro miligramos mg), tipos de fluidos y por via oral de desintegracion pildoras.

Es necesario llevarlo por via oral junto con los alimentos asociados con sin tener esto. Llevelo junto con el agua potable.

Es recomendable considerar Ispidon cada dia al mismo tiempo un par de veces cada dia.

Ispidon se podria proporcionar a los enfermos de mas edad 5-16 junto con el autismo.

Mantengase alejado de consumir gaseosas o el te verde, incluso junto con Ispidon.

Si usted desea lograr mejores resultados por lo general no dejar de usar Ispidon, de repente.

Ispidon (Risperdal) Careciendo asocia con dosis

Por lo general, no reciben doble dosis. En caso de que salte la dosis que necesita para llevar una vez se tiene en cuenta en lo que respecta a su deficiente. Cuando es hora de la dosis que necesita para llevar a cabo su propia rutina de dosificacion normal.

Ispidon (Risperdal)

En el caso de una sobredosis Ispidon y que tambien se evita gran usted necesita comprobar hacia fuera su medico o incluso el medico de inmediato. Asociado con la sobredosis Ispidon: espasmo muscular, temperatura, desmayos, sudoracion, provocacion, latido anormal del corazon o incluso rapida, fatiga, sensacion de sueno, vision borrosa, vientre molesto.

Ispidon (Risperdal) Espacio de almacenamiento

La tienda de las temperaturas del espacio entre los quince con el fin de veinticinco niveles D (59, asi como setenta y siete niveles F) de humedad, asi como la temperatura. Fortalecer cualquier tipo de medicamento sin tocar a partir del dia de vencimiento. Mantener desde el lograr de los ninos.

Ispidon (Risperdal) Efectos negativos

Ispidon ofrece los efectos negativos. El mas tipico tienden a ser:

material de friccion fatiga

nauseas o vomitos material de friccion

material de friccion zona nasal nasal

molestias asociadas con material de friccion de la masa muscular

material de friccion diarrea

sensacion material de friccion con sueno

mejora material de friccion hambre

aumento de peso material de friccion

material de friccion de reflujo acido

material de friccion ansiedad

material de friccion area de la boca molestias asociadas con material de friccion vientre

seca

material de friccion congestion

material de friccion migrana

material de friccion vision borrosa

material de friccion que hace pis molestos

friccion insomnio materiales

material de friccion artralgia

problemas intimos material de friccion

Mucho menos tipica y severos efectos negativos en todo el uso de Ispidon:

respuestas reaccion alergica (urticaria, inhalando y exhalando, cuestiones de alergia, asi como la erupcion) material de friccion

material de friccion temperatura

cardiaco anormal vencio

material de friccion espasmo muscular

hombres desagradable material de friccion del pene ereccion

estado desconcertado de material de friccion mente

muy rapidamente corazon lata material de friccion

antojos de alimentos severas material de friccion

material de friccion rigidez

materiales de friccion latido del corazon rapido o incluso anormal

acciones inmanejables desde el encuentro, la cadera y las piernas, las manos material de friccion

material de friccion de la transpiracion

pobre performace asociado con material de friccion acciones

Los efectos negativos indicaciones se basan en la medicacion que podria estar utilizando pero, ademas, confiar en su condicion de bienestar y otros aspectos.

Ispidon (Risperdal) Contraindicaciones

Por lo general no reciben Ispidon en caso de que son sensibles con el fin de elementos Ispidon.

Tenga cuidado junto con Ispidon si usted esta esperando otra manera tiene la intencion de tener un hijo, si no que realmente eres una mama medica.

Mantengase alejado de consumir gaseosas o el te verde, incluso junto con Ispidon.

Mantengase alejado de su llegar a ser demasiado caliente.

Juega el papel de cautela, junto con la utilizacion de Ispidon en caso de conseguir organo hepatico, cardiovascular o enfermedad renal incluso, convulsiones, enfermedad de Parkinson, el cancer de la mama, la diabetes, anginas.

Juega el papel de cautela, junto con la utilizacion de Ispidon en el caso de la utilizacion de medicamentos porque la acidez valproico (Depakote, Depakene), antidepresivos, paroxetina (Paxil), medicamentos para la presion arterial baja mas bajos, ranitidina (Zantac), clozapina (Clozaril), carbamazepina (Tegretol), medicamentos Enfermedad de Parkinson debido a la bromocriptina (Parlodel), pergolida (Permax), levodopa (Sinemet, Atamet, drogar, Larodopa), ropinirol (Requip), pramipexol (Mirapex).

Seniors enfermos que son mas de 66 anos debe ser cauteloso junto con dosis de Ispidon.

Mantengase alejado de medicamentos provocado somnolencia.

Evite las bebidas alcoholicas.

Tenga cuidado si usted quiere tener un tratamiento quirurgico.

Prevenir itinerante dispositivo.

Por lo general, no dejar de fumar lleve todo de repente.

Ispidon (Risperdal) Preguntas comunes

Queen: Exactamente ?que implica Ispidon?

El: Ispidon es realmente una medicina junto con elementos extremadamente creados que se consume en la reparacion de los graves problemas por ejemplo, grupos de apoyo bipolar, Odio, la esquizofrenia, asi como sus signos y sintomas. Ispidon tambien puede ser ideal para los enfermos de mas edad 5-16 junto con autism. A

Queen: ?Que son exactamente los de marca, asi como las marcas generales asociados con Ispidon?

El: titulo general asociada con Ispidon es en realidad risperidona. Marcas asociadas con Ispidon tienden a ser Ispidon, Ispidon Consta, Ispidon M-Tab. A

Reina: ?Como puede realmente hace carrera Ispidon?

El: obras Ispidon proporcionando mentes estabilidad, asi como balance. A psicologica

Queen: ?Que es exactamente el enfoque en Ispidon?

El: Ispidon se encuentra a traves de expertos de las drogas con el fin de luchar contra los problemas psicologicos (trastorno bipolar, odio, la esquizofrenia, asi como para los enfermos de mas edad 5-16 junto con el autismo). Concentrese en asociado con Ispidon seria para administrar a permanecer stability. A de cerebro

Queen: Que las mujeres que estan embarazadas utilizar Ispidon?

El: Juega el papel de cautela junto con Ispidon cuando usted esta esperando y tiene nurseling. A

Queen: Los profesionales de la salud | | Personal | Mis propios, personales | Terminos de busqueda | Mi propia, personal | profesional medico | Publicado | proveedor de cuidado de la salud | Mi negocio | Todos los de mi | De mi | Excelente | Mis propios personales | frases de palabras clave | A | Oferta | Economico | El dia a dia | Pagina web> chico es en realidad, de dieciseis anos de edad. Que este individuo obtener Ispidon?

El: Ispidon se podria proporcionar a los enfermos de mas edad 5-16 junto con autism. A

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Los sufridores: que son mas de 66 anos debe ser cauteloso junto con Ispidon dose. A Mayores

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El: Por lo general no utilizan Ispidon en caso de que son sensibles con el fin de elementos Ispidon. Mantengase alejado de consumir gaseosas o el te verde, incluso junto con Ispidon. Utilizar meticulosamente Ispidon en el caso de que usted desea ir a traves de un procedimiento quirurgico (dental o algun tipo de otra). Mantengase alejado de su llegar a ser demasiado caliente. Mantengase alejado de los medicamentos provocado somnolencia. Si usted desea lograr mejores resultados, sin efectos negativos, es aconsejable evitar las bebidas alcoholicas. Mantengase alejado de viajar dispositivo. Puede ser danino para evitar el uso de Ispidon todo de un sudden. A

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Tamoxifen Uses, Dosage, Side Effects, Tamofen

Tamoxifen

Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow.

Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer).

Tamoxifen may also be used for purposes not listed in this medication guide.

Important information

Do not use tamoxifen if you are pregnant. It could harm the unborn baby. Use a barrier form of birth control (such as a condom or diaphragm with spermicide) while you are using this medication and for at least 2 months after your treatment ends. You should not use tamoxifen if you are allergic to it, or if you have a history of blood clots in your veins or your lungs, or if you are also taking a blood thinner such as warfarin (Coumadin).

Before using this medicine, tell your doctor if you have liver disease, high triglycerides (a type of fat in the blood), a history of cataract, or a history of stroke or blood clot. Also tell your doctor if you if you are receiving chemotherapy or radiation treatment.

If you are taking tamoxifen to reduce your risk of breast cancer, you may need to take your first dose while you are having a menstrual period. You may also need to have a pregnancy test before you start taking this medicine, to make sure you are not pregnant. Follow your doctor's instructions.

Taking tamoxifen may increase your risk of uterine cancer, stroke, or a blood clot in the lung, which can be fatal. Talk with your doctor about your specific risks in taking this medication.

To make sure this medication is not causing harmful effects, your doctor may want you to have mammograms and to perform routine breast self exams on a regular basis. Your liver function may also need to be tested. Visit your doctor regularly.

Before taking this medicine

You should not use tamoxifen if you are allergic to it.

You should not use tamoxifen to reduce your risk of breast cancer if you are also taking a blood thinner such as warfarin (Coumadin, Jantoven).

Do not take tamoxifen if you are pregnant. It could harm the unborn baby. Avoid becoming pregnant while you are using this medicine, and for at least 2 months after your treatment ends.

Hormonal contraception (such as birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy while taking tamoxifen. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide, or intrauterine device/IUD).

If you are taking tamoxifen to reduce your risk of breast cancer . you may need to take your first dose while you are having a menstrual period. You may also need to have a pregnancy test before you start taking tamoxifen, to make sure you are not pregnant. Follow your doctor's instructions.

Taking tamoxifen may increase your risk of uterine cancer, stroke, or a blood clot in the lung, which can be fatal. Talk with your doctor about your specific risks in taking this medicine.

To make sure tamoxifen is safe for you, tell your doctor if you have:

a history of stroke or blood clot;

high cholesterol or triglycerides (a type of fat in the blood);

a history of cataracts; or

if you are receiving chemotherapy or radiation.

It is not known whether tamoxifen passes into breast milk or if it could harm a nursing baby. This medicine may slow breast milk production. You should not breast-feed while taking tamoxifen.

How should I take tamoxifen?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Tamoxifen can be taken with or without food.

While using tamoxifen, you may need frequent blood tests.

If you need surgery or medical tests or if you will be on bed rest . you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are taking tamoxifen.

Have regular physical exams and mammograms, and self-examine your breasts for lumps on a monthly basis while using this medicine.

Use tamoxifen regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. You may need to keep using this medication for up to 5 years.

Store at room temperature away from moisture, heat, or cold. Do not freeze.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking tamoxifen?

This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Tamoxifen side effects

Get emergency medical help if you have signs of an allergic reaction to tamoxifen: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tamoxifen can increase your risk of stroke or blood clots. Call your doctor at once if you have :

signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;

signs of a blood clot in the lung - chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or

signs of a blood clot in your leg - pain, swelling, warmth, or redness in one or both legs.

Also call your doctor at once if you have:

blurred vision, tunnel vision, eye pain, or seeing halos around lights;

unusual vaginal bleeding or discharge;

changes in your menstrual periods;

pain or pressure in your pelvic area;

a new breast lump;

liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

high levels of calcium in your blood - vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, confusion, lack of energy, or tired feeling.

Common tamoxifen ide effects may include:

vaginal discharge; or

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tamoxifen dosing information

Usual Adult Dose for Breast Cancer:

For the treatment of metastatic breast cancer in women and men: 20 to 40 mg orally Dosages greater than 20 mg should be given in divided doses (morning and evening).

For the treatment of women with Ductal Carcinoma in Situ, following breast surgery and radiation: 20 mg orally daily for 5 years.

To reduce the incidence of breast cancer in women at high risk for breast cancer: 20 mg orally daily for 5 years.

Usual Adult Dose for Breast Cancer - Adjuvant:

For the treatment of node-positive breast cancer in postmenopausal women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation: 10 mg orally 2 to 3 times a day for 5 years.

Usual Adult Dose for Breast Cancer - Palliative:

10 to 20 mg orally twice a day

A beneficial response may not be evident for several months after initiation of therapy.

Usual Pediatric Dose for McCune-Albright Syndrome:

For use in girls age 2 to 10 years with McCune-Albright Syndrome and precocious puberty: 20 mg once a day. The duration of treatment is up to 12 months.

Usual Pediatric Dose for Precocious Puberty:

For use in girls age 2 to 10 years with McCune-Albright Syndrome and precocious puberty: 20 mg once a day. The duration of treatment is up to 12 months.

What other drugs will affect tamoxifen?

Many drugs can interact with tamoxifen, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with tamoxifen. Give a list of all your medicines to any healthcare provider who treats you.

More about tamoxifen

Consumer resources

Professional resources

Related treatment guides

Where can I get more information?

Your pharmacist can provide more information about tamoxifen.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use tamoxifen only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 8.04. Revision Date: 2015-08-04, 2:24:52 PM.

Drug Status

Availability Rx Prescription only

Pregnancy Category D Positive evidence of risk

CSA Schedule N Not a controlled drug

Approval History Calendar Drug history at FDA

Clergy - Definition Of Clergy By The Free Dictionary, Lergy

clergy

The body of people ordained or recognized by a religious community as ritual or spiritual leaders. See Usage Note at collective noun .

[Middle English clergie . from Old French (from Vulgar Latin *clercīa . from Late Latin clēricus ; see clerk ) and from Old French clergie . body of clerks (from Vulgar Latin *clercātus . from Late Latin clēricātus . from clēricus . clerk, cleric ).]

clergy

(Ecclesiastical Terms) the collective body of men and women ordained as religious ministers, esp of the Christian Church.

[C13: from Old French clergie, from clerc ecclesiastic, clerk]

cler•gy

the group or body of ordained persons in a religion, as distinguished from the laity.

[1175–1225; Middle English clerge, clergie < Old French clerge < Late Latin clericātus office of a priest; see cleric. - ate 3 ]

clergy

Religious leaders; a member of the Church.

clergy

clergy

the ministers, priests etc of the Christian religion. the clergy of the Church of England. geestelikes ???????? ????? ??????? духовенство clero duchovenstvo die Geistlichkeit pr?stestand; gejstlighed ?????? clero vaimulikkond ????????? ?????? papisto clerge ????? ????? svecenstvo papsag pejabat gereja klerkastett clero ??? ??? dvasininkija garidznieciba golongan paderi geestelijkheid presteskap. geistlighet duchowienstwo ??? ?? ? ????? ????? ???? clero cler духовенство duchovenstvo duhovscina svestenstvo prasterskap, praster ??????????????????????; ???????????????? rahipler/papazlar s?n?f? ?? духовенство, духівництво ????? ? ????? giao s? ??

one of the clergy; a priest, minister etc . geestelike, predikant ?????? ??? духовник clerigo duchovni, knez der/die Geistliche pr?st; gejstlig ???????? clerigo vaimulik ??? ??????? ???? pappi ecclesiastique ???, ???? ????? svecenik, duhovnik (aglikanski) pap pejabat gereja, pendeta dsb prestur, klerkur ecclesiastico ??? ??? ? ?? dvasininkas garidznieks paderi geestelijke prest. geistlig duchowny ???: ?????? clerigo preot, cleric духовное лицо duchovny duhovnik svestenik prast ??????????????????????????? papaz. rahip ?? священик, духовна особа ????? giao s? Co d?c ??

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I say it only shows his foolish, impious pride, and abominable, devilish rebellion against the reverend clergy .

O, because I have had only that kind of benevolence which consists in lying on a sofa, and cursing the church and clergy for not being martyrs and confessors.

The king sat under a canopy of state; about him were clustered a large body of the clergy in full canonicals.

The amphitheatre was packed, from the bull-ring to the highest row - twelve thousand people in one circling mass, one slanting, solid mass - royalties, nobles, clergy. ladies, gentlemen, state officials, generals, admirals, soldiers, sailors, lawyers, thieves, merchants, brokers, cooks, housemaids, scullery-maids, doubtful women, dudes, gamblers, beggars, loafers, tramps, American ladies, gentlemen, preachers, English ladies, gentlemen, preachers, German ditto, French ditto, and so on and so on, all the world represented: Spaniards to admire and praise, foreigners to enjoy and go home and find fault - there they were, one solid, sloping, circling sweep of rippling and flashing color under the downpour of the summer sun - just a garden, a gaudy, gorgeous flower-garden

I am a clergyman," he said; "and the clergy are often appealed to about odd matters.

As I was saying; if Monsieur Manette had not died; if he had suddenly and silently disappeared; if he had been spirited away; if it had not been difficult to guess to what dreadful place, though no art could trace him; if he had an enemy in some compatriot who could exercise a privilege that I in my own time have known the boldest people afraid to speak of in a whisper, across the water there; for instance, the privilege of filling up blank forms for the consignment of any one to the oblivion of a prison for any length of time; if his wife had implored the king, the queen, the court, the clergy. for any tidings of him, and all quite in vain;--then the history of your father would have been the history of this unfortunate gentleman, the Doctor of Beauvais.

Yet so loose were the ideas of the times respecting the conduct of the clergy. whether secular or regular, that the Prior Aymer maintained a fair character in the neighbourhood of his abbey.

These were searched and sought out through the whole nation, by the prince and his wisest counsellors, among such of the priesthood as were most deservedly distinguished by the sanctity of their lives, and the depth of their erudition; who were indeed the spiritual fathers of the clergy and the people.

He knew the present temper of the people, that those of the greatest interest and power were by no means pleased with the changes of religion, and only waited for a fair opportunity to revolt; and that these discontents were everywhere heightened by the monks and clergy .

And he has also left other directions which the clergy of the village say should not and must not be obeyed because they savour of paganism.

My chief war is against the clergy and barons of the land who bear down upon the poor.

This salon, in which the lesser nobility, the clergy. and the magistracy meet together, exerts a great influence.

Fluconazol Medlineplus Medicinas, Fluconazon

Fluconazol

?Para cuales condiciones o enfermedades se prescribe este medicamento?

El fluconazol se usa para tratar las infecciones por hongos, incluidas las infecciones por levaduras de la vagina, la boca, la garganta, el esofago (el conducto que va desde la boca hasta el estomago), el abdomen (el area entre el pecho y la cintura), los pulmones, la sangre y otros organos. El fluconazol tambien se usa para tratar la meningitis (infeccion de las membranas que recubren el cerebro y la columna vertebral) provocada por hongos. El fluconazol tambien se usa para prevenir las infecciones por levaduras en pacientes que es probable que se infecten porque estan siendo tratados con quimioterapia o radioterapia antes de un trasplante de medula osea (reemplazo del tejido esponjoso enfermo dentro de los huesos con tejido sano). El fluconazol pertenece a una clase de antimicoticos llamados triazoles. Actua haciendo mas lento el crecimiento de los hongos que causan la infeccion.

?Como se debe usar este medicamento?

La presentacion del fluconazol es en tabletas y en una suspension (liquido) para administrarse por via oral. Por lo general, suele tomarse con o sin alimentos, una vez al dia. Quizas deba tomar una sola dosis de fluconazol o quizas deba tomar fluconazol durante varias semanas o mas. La duracion del tratamiento depende de su afeccion y de que tan bien responde al fluconazol. Siga atentamente las instrucciones del medicamento recetado, y pidales a su medico o a su farmaceutico que le expliquen cualquier cosa que no entienda. Tome el fluconazol segun lo indicado. No aumente ni disminuya la dosis, ni la tome con mas frecuencia que la indicada por su medico.

Es posible que su medico le indique una dosis doble de fluconazol el primer dia de su tratamiento. Siga estas instrucciones al pie de la letra.

Agite bien el liquido antes de cada uso para mezclar uniformemente el medicamento.

Deberia comenzar a sentirse mejor a los pocos dias de tratamiento con fluconazol. Si los sintomas no mejoran, o si empeoran, llame a su medico.

Siga usando fluconazol hasta que su medico le indique que deje de hacerlo, aunque se sienta mejor. No deje de tomar fluconazol sin consultar a su medico. Si deja de tomar fluconazol demasiado pronto, es posible que su infeccion regrese despues de poco tiempo.

Pidales a su medico o a su farmaceutico una copia de la informacion del fabricante para el paciente.

?Que otro uso se le da a este medicamento?

El fluconazol, a veces, tambien se usa para tratar infecciones graves por hongos, que comienzan en los pulmones y pueden propagarse a traves del cuerpo, e infecciones por hongos de los ojos, la prostata (un organo reproductor masculino), la piel y las unas. El fluconazol, a veces, tambien se usa para prevenir las infecciones por hongos en las personas que son mas propensas a infectarse porque tienen el virus de la inmunodeficiencia humana (VIH) o cancer o han tenido una operacion de trasplante (cirugia para extraer un organo y reemplazarlo con el organo de un donante o con un organo artificial). Consulte a su medico sobre los posibles riesgos de usar este medicamento para tratar su afeccion.

Este medicamento puede recetarse para otros usos; pidales mas informacion a su medico o a su farmaceutico.

?Cuales son las precauciones especiales que debo seguir?

Antes de tomar fluconazol:

Informe a su medico y a su farmaceutico si es alergico al fluconazol, a otros medicamentos antimicoticos como el itraconazol (Sporanox), ketoconazol (Nizoral), posaconazol (Noxafil) o voriconazol (Vfend), a algun otro medicamento o a alguno de los ingredientes en las tabletas o en la suspension de fluconazol. Pidale a su farmaceutico una lista de los ingredientes.

Informe a su medico si esta tomando astemizol (Hismanal) (no se vende en los EE. UU.), cisaprida (Propulsid) (no se vende en los EE. UU.), eritromicina (E. E.S. E-Mycin, Erythrocin); pimozida (Orap), quinidina (Quinidex) o terfenadina (Seldane) (no se vende en los EE. UU.). Es probable que su medico le indique no tomar fluconazol si esta tomando alguno de estos medicamentos.

Informe a su medico y a su farmaceutico que medicamentos con y sin receta, vitaminas, suplementos nutricionales y productos herbarios esta tomando o planea tomar. Ademas, informe a su medico que ha recibido fluconazol antes de comenzar a tomar cualquier medicamento nuevo en el termino de 7 dias de recibir fluconazol. No olvide mencionar ninguno de los siguientes: amitriptilina; anfotericina B (Abelcet, AmBisome, Amphotec, Fungizone); anticoagulantes (“diluyentes de la sangre”) como warfarina (Coumadin, Jantoven); benzodiazepinas como midazolam (Versed); bloqueadores de los canales de calcio, como amlodipina (Norvasc, en Caduet, en Lotrel), felodipina (Plendil, en Lexxel), isradipina (DynaCirc) y nifedipina (Adalat, Procardia); carbamazepina (Carbatrol, Epitol, Tegretol); celecoxib (Celebrex); medicamentos reductores del colesterol (estatinas), como atorvastatina (Lipitor, en Caduet), fluvastatina (Lescol) y simvastatina (Zocor, en Simcor, en Vytorin); clopidogrel (Plavix); ciclofosfamida (Cytoxan); ciclosporina (Gengraf, Neoral, Sandimmune); diureticos (“pastillas contra la retencion de agua”) como hidroclorotiazida (HydroDIURIL, Microzide); fentanilo (Actiq, Duragesic, Fentora, Sublimaze); isoniazida (INH, Nydrazid); losartan (Cozaar, en Hyzaar); metadona (Methadose); nevirapina (Viramune); medicamentos antiinflamatorios no esteroides (NSAID, por sus siglas en ingles) como ibuprofeno (Advil, Motrin, otros) y naproxeno (Aleve, Anaprox, Naprelan); anticonceptivos orales (pildoras anticonceptivas); medicamentos orales para la diabetes como glipizida (Glucotrol), gliburida (Diabeta, Micronase, Glycron, otros) y tolbutamida (Orinase); nortriptilina (Pamelor); fenitoina (Dilantin, Phenytek); prednisona (Sterapred); rifabutina (Mycobutin); rifampina (Rifadin, Rimactane, en Rifamate, en Rifater); saquinavir (Invirase); sirolimus (Rapamune); tacrolimus (Prograf); teofilina (Elixophyllin, Theo-24, Uniphyl, otros); tofacitinib (Xeljanz); triazolam (Halcion); acido valproico (Depakene, Depakote); vimblastina; vincristina; vitamina A; voriconazol (Vfend); y zidovudina (Retrovir). Es posible que su medico deba cambiar las dosis de sus medicamentos o vigilarlo de cerca por si presentara efectos secundarios. Muchos otros medicamentos tambien pueden interactuar con el fluconazol, por lo que no olvide informar a su medico sobre todos los medicamentos que esta tomando, incluso los que no aparezcan en esta lista.

Informe a su medico si tiene o alguna vez ha tenido cancer; el sindrome de inmunodeficiencia adquirida (SIDA); latidos cardiacos irregulares; niveles bajos de calcio, sodio, magnesio o potasio en la sangre; afecciones hereditarias poco comunes en las que el cuerpo no puede tolerar la lactosa o la sacarosa; o enfermedad del corazon, de los rinones o del higado.

Informe a su medico si esta embarazada, sobre todo si esta en los primeros 3 meses de embarazo, si planea quedar embarazada o si esta dando el pecho. Si queda embarazada mientras toma fluconazol, llame a su medico. El fluconazol puede causarle danos al feto.

Si se va a realizar una cirugia, incluso una cirugia dental, informe al medico o al dentista que esta tomando fluconazol.

Tenga en cuenta que el fluconazol puede provocarle mareos o convulsiones. No conduzca vehiculos ni opere maquinaria hasta que sepa como le afecta este medicamento.

?Que dieta especial debo seguir mientras tomo este medicamento?

Trental Side Effects In Detail, Tarontal

Trental Side Effects

Note: This page contains side effects data for the generic drug pentoxifylline. It is possible that some of the dosage forms included below may not apply to the brand name Trental.

In Summary

Common side effects of Trental include: dizziness and nausea. Other side effects include: dyspepsia and vomiting. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to pentoxifylline: oral tablet extended release

As well as its needed effects, pentoxifylline (the active ingredient contained in Trental) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking pentoxifylline, check with your doctor or nurse as soon as possible:

Rare

Chest pain

irregular heartbeat

Signs and symptoms of overdose (in the order in which they may occur)

Drowsiness

flushing

faintness

unusual excitement

convulsions (seizures)

Minor Side Effects

Some pentoxifylline side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common:

Dizziness

headache

nausea or vomiting

stomach discomfort

For Healthcare Professionals

Applies to pentoxifylline: compounding powder, oral tablet extended release

General

Pentoxifylline (the active ingredient contained in Trental) has been generally well tolerated. While typically minor, side effects have necessitated discontinuation of the drug in approximately 3% of treated patients. Tolerance to mild side effects generally has developed with continued use. [Ref ]

Gastrointestinal

Gastrointestinal side effects have been the most common side effects associated with pentoxifylline (the active ingredient contained in Trental) therapy and have included dyspepsia, nausea, vomiting, and belching, which occurred in 1% to 3% of patients. Some smaller studies have reported gastrointestinal disturbance in up to 33% of patients treated with pentoxifylline. [Ref ]

Nervous system

Nervous system side effects have occurred in 1% to 2% of treated patients and have included headache, dizziness, insomnia, and tremor. Some smaller studies have reported nervous system adverse effects in up to 17% of treated patients. In addition, rare cases of visual and auditory hallucinations have been reported. Aseptic meningitis has been reported in postmarketing experiences. [Ref ]

Cardiovascular

Cardiovascular side effects have included reports of palpitations, flushing, and angina. These reports have usually been associated with higher doses of an immediate release capsule which is not available in the United States. [Ref ]

Hematologic

Hematologic side effects have included anecdotal reports of pancytopenia and fatal aplastic anemia. [Ref ]

Hepatic

Hepatic side effects have included postmarketing reports of cholestasis.

Hypersensitivity

Hypersensitivity side effects have included postmarketing reports of anaphylactic reaction, anaphylactoid reaction, and anaphylactic shock.

References

1. "Product Information. Trental (pentoxifylline)." Hoechst Marion-Roussel Inc, Kansas City, MO.

2. Dettelbach HR, Aviado DM "Clinical pharmacology of pentoxifylline with special reference to its hemorrheologic effect for the treatment of intermittent claudication." J Clin Pharmacol 25 (1985): 8-26

3. Witter FR, Smith RV "The excretion of pentoxifylline and its metabolites into human breast milk." Am J Obstet Gynecol 151 (1985): 1094-7

4. Ward A, Clissold SP "Pentoxifylline: a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy." Drugs 34 (1987): 50-97

5. Green RM, McNamara J "The effects of pentoxifylline on patients with intermittent claudication." J Vasc Surg 7 (1988): 356-62

6. Lucas MA "Prevention of post-operative thrombosis in peripheral arteriopathies. Pentoxifylline vs. conventional antiaggregants: a six-month randomized follow-up study." Angiology 35 (1984): 443-50

7. Baker DE, Campbell RK "Pentoxifylline: a new agent for intermittent claudication." Drug Intell Clin Pharm 19 (1985): 345-8

8. Crowder JE, Cohn JB, Savitsky JP, Morgan DL, Slywka J, Cobert BL, Hryniewicki SW, Piccirillo RT, Wilcox CS "Efficacy and safety of pentoxifylline in geriatric patients with intermittent claudication." Angiology 40 (1989): 795-802

9. Gilbert GJ "Pentoxifylline-induced musical hallucinations." Neurology 43 (1993): 1621-2

10. Pitner J, Simpson W, Gutierrez S, Mintzer J "Pentoxifylline (Trental)-induced visual hallucinations." J Am Geriatr Soc 41 (1993): 782-3

11. Mass RD, Venook AP, Linker CA, Zipkin RE "Pentoxifylline and aplastic anemia." Ann Intern Med 107 (1987): 427-8

It is possible that some side effects of Trental may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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Limnos Greece, Greek Islands, Lemnos, Limnos

Limnos

Limnos or Lemnos is a beautiful island situated in the north Aegean sea. It is a volcanic island, and therefore was the god of fire Hephaestus especially worshipped here in antiquity. A very green and lush island, it has blessed its people with fertile soil where they grow olives, fruit and wheat, breed animals and make honey of the many flowers that covers Limnos. In general, the islanders here are quite traditional, which means they still hold hospitality as something almost sacred, and have kept many old customs. For holidaymakers, Limnos offers nice beaches and lot of things to see. The island is a popular summer resort for both Greeks and foreigners but has kept its genuine atmosphere.

History

According to mythology, the goddess Hera got very angry with her son Hephaestus one day, and threw him off Mt. Olympus. He landed on Limnos, where he was taken care of by the people, making the island his special place. Although some myths refer to Sicily as his workshop, others hold that he worked on Limnos. What is certain, though, is that Hephaestus was the patron god of this island, and that at least one temple was built to his honour here. Another story tells us about the angry women of Limnos who murdered all the men of the island after a long time of feeling neglected by their husbands. They chased away their king Thoas, and ruled their island as they liked. When Jason and the Argonauts made a stop at the island, they stayed for while with the women, made them pregnant, and so, Limnos was to have a male population once more. Archaeological excavations have found evidence of very early settlements on Limnos. There are theories that one of the first peoples were the Etruscans. Limnos was part of the Persian empire in the 5th century BC, and when Greece had defeated their enemy, it joined the Athenian League. Then followed the same line of rulers as in the rest of the Aegean: the Macedonians. Romans, The Byzantine empire, the Genuans, Venetians and the Turks. The island also suffered several pirate attacks, and when the war of independence begun in 1821, Limnos fought bravely. The island was liberated in 1912.

What to see

Above Myrina, Limno's capital, towers the kastro. It was probably an acropolis in antiquity, but what we see today dates back to the Venetians. There is also an interesting archaeological museum in Myrina, with findings from around the island. In Myrina there is an archeological museum that is worth a visit as it houses many ancient relics and ceramics excavated from nearby Polyohni and dating from prehistoric times. As well as finds from Polyohni there are also relics from Myrina, Hephaestea and Kavirio Poliochni is also an ancient settlement that has been excavated on the island. Its people left in the middle of the 2nd Millennium BC, probably because of an earthquake. At Repanidi there ruins of a castle from the Byzantine era. The Church of Life-giving Source (Zoodochos Pigis) is important for those interested in history, since there is a statue here of the young girl called Maroula, and who fought the Turks on her own in the 15th century. Not far from Myrina is the large picturesque village of Kondias with its traditional island mansions. 28 km from Myrina is the village of Kaminia. Here you can see the ruins of the ancient settlement of Polyohni. Close to Kaminia is the village of Moudros which used to be the old capital of Limnos. Heading north-east from here is the village of Kondopouli where the two ancient settlements of Hephaestea and Kavirio can be seen. At Hephaestea are the ruins of an ancient settlement that you can visit. Even though the place was settled way before then, there are findings of temples and a Roman theatre here. Nearby is located the Temple of Kavirio which was probably used for religious ceremonies in ancient times. At the north-east tip of the island is the village of Plaka where you will find the spa at Agios Haralambos. At Skandali you can also visit the monastery of Agios Sozon.

What to do

You can do watersports on several of the beaches of Lemnos, and there are also tennis courts and a golf course. In Mirinia there is a cinema, and all films are shown in their original language with Greek subtitles.

Beaches

Limnos has many beaches. You can go searching for your own, quiet spot if you want, or visit the more popular ones, for example Fanaraki, Riha Nera, Romeicos Gialos and Kaminia. With a coastline of 259km there are many beautiful sandy beaches to be found all over the island. Close to Myrina you can enjoy the shallow waters and golden sands of beaches like Romeikos Gialos, and Riha Nera. Beautiful sandy beaches are not hard to find. Try too the beaches of Avlona and Plati. At the village of Kondias is the pretty sandy beach of Evgati and enjoyable swimming to be had at Kotsinas near Repanidi. The beach of Varoskopos, close to the village of Kaminia is attractive whereas south-east at Moudros is the beach of Fanaraki with the beach of Agios Gianis close by. On the north-east coast of the island, not far from Plaka is the small village of Panagia. There are some lovely beaches also around this whole area, such as Agia Sotiras and, a little further, Kolokithi beach.

Nightlife

The nightlife here is quite good, without being too wild. You'll find several bars and clubs in Myrina..

Food

Limnos is an excellent island for trying out some really genuine meals. There are many restaurants in Myrina and the villages, but you should ask for the local specialties if you really want a taste of Limnos. There are various seafood specialties, local cheese, honey and wine, as well as a renowned halva - a kind of sweet.

Shopping

You'll find quite a few shops in Myrina. There, they sell textiles and jewellery, but the most typical thing you can get from Limnos is some of its wine or honey.

Getting Around

Transportation on the island is good with local buses connecting all the main villages and towns. there are also taxis and vehicles for rent on the island, as well as boats that go to the various beaches.

Getting there

There are flights to Limnos from Athens, and you can also get a ferry boat from Rafina to get here. There is also ferry connections to Limnos from Lesvos, Chios and Thessaloniki. Limnos has ferry connections with Mykonos, Paros Syros, Kos, Patmos and Rhodes as well as Volos Kavala and Alexandropoulis in Northern Greece.

Facts about Limnos

Size: 476 sq. km International code: 0030 Population: about 16 000 Local code: 22540 Cashmachine: Yes Hospital: 22222. 23333 Internet cafe: Yes Port Police: 22823 Highest Mountain: Skopia 470m Police: 22200 Airport: Yes Tourist Office: Tour Operators: Airport: 29428 Hotel Association: Tourist Police: 22221 Fire Brigade: 22199

Sharox Indication, Action Of Sharox, Interactions, Sharox

Sharox [in more detail]

Sharox Indication:

For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.

Sharox Mechanism Of Action:

Sharox, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefuroxime interferes with an autolysin inhibitor.

Sharox Drug Interactions:

Probenecid Probenecid increases the antibiotic's level

Food Interactions:

Take with food to increase absorption.

Cratifen, Cratifen

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Claritin Eye (Ketotifen)

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Tunalmin, Tunalmin

Carafate is indicated in:

Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.

Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.

Carafate is a gastric protective. It works by forming a protective layer on the ulcer to serve as a barrier against acid, bile salts, and enzymes in the stomach.

Use Carafate as directed by your doctor.

Take Carafate by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

Do not take an antacid for at least 30 minutes before or after taking Carafate.

It may take 4 to 8 weeks for complete healing of your ulcer. Continue taking Carafate for the full course of treatment even if you feel better.

Do not take Carafate at the same time as other medicines. Take Carafate at least 2 hours after other medicines. If you are not sure about the best time to take Carafate, ask your doctor or pharmacist.

If you miss a dose of Carafate, take it as soon as possible. If it is almost time for your next dose, go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carafate.

Store Carafate at room temperature, between 68 and 77 degrees (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Carafate out of the reach of children and away from pets.

Active Ingredient: Sucralfate.

Do NOT use Carafate if:

you are allergic to any ingredient in Carafate.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Carafate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have kidney problems or are on dialysis, or have blockage of the intestines or difficulty swallowing.

Some medicines may interact with Carafate. Tell your health care provider if you are taking any other medicines, especially any of the following:

Citrate salts or medicines that contain aluminum, specifically in patients with kidney disease, because side effects from aluminum buildup may occur.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Carafate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Carafate may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Take Carafate with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Carafate has aluminum in it. Before you start any new medicine, check the label to see if it has aluminum in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Carafate should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Carafate while you are pregnant. It is not known if Carafate is found in breast milk. If you are or will be breast-feeding while you take Carafate, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; dizziness; feeling of a whirling motion.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Carafate is indicated in:

Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.

Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.

Carafate is a gastric protective. It works by forming a protective layer on the ulcer to serve as a barrier against acid, bile salts, and enzymes in the stomach.

Use Carafate as directed by your doctor.

Take Carafate by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

Do not take an antacid for at least 30 minutes before or after taking Carafate.

It may take 4 to 8 weeks for complete healing of your ulcer. Continue taking Carafate for the full course of treatment even if you feel better.

Do not take Carafate at the same time as other medicines. Take Carafate at least 2 hours after other medicines. If you are not sure about the best time to take Carafate, ask your doctor or pharmacist.

If you miss a dose of Carafate, take it as soon as possible. If it is almost time for your next dose, go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carafate.

Store Carafate at room temperature, between 68 and 77 degrees (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Carafate out of the reach of children and away from pets.

Active Ingredient: Sucralfate.

Do NOT use Carafate if:

you are allergic to any ingredient in Carafate.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Carafate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have kidney problems or are on dialysis, or have blockage of the intestines or difficulty swallowing.

Some medicines may interact with Carafate. Tell your health care provider if you are taking any other medicines, especially any of the following:

Citrate salts or medicines that contain aluminum, specifically in patients with kidney disease, because side effects from aluminum buildup may occur.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Carafate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Carafate may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Take Carafate with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Carafate has aluminum in it. Before you start any new medicine, check the label to see if it has aluminum in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Carafate should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Carafate while you are pregnant. It is not known if Carafate is found in breast milk. If you are or will be breast-feeding while you take Carafate, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; dizziness; feeling of a whirling motion.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Carafate is indicated in:

Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.

Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.

Carafate is a gastric protective. It works by forming a protective layer on the ulcer to serve as a barrier against acid, bile salts, and enzymes in the stomach.

Use Carafate as directed by your doctor.

Take Carafate by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

Do not take an antacid for at least 30 minutes before or after taking Carafate.

It may take 4 to 8 weeks for complete healing of your ulcer. Continue taking Carafate for the full course of treatment even if you feel better.

Do not take Carafate at the same time as other medicines. Take Carafate at least 2 hours after other medicines. If you are not sure about the best time to take Carafate, ask your doctor or pharmacist.

If you miss a dose of Carafate, take it as soon as possible. If it is almost time for your next dose, go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carafate.

Store Carafate at room temperature, between 68 and 77 degrees (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Carafate out of the reach of children and away from pets.

Active Ingredient: Sucralfate.

Do NOT use Carafate if:

you are allergic to any ingredient in Carafate.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Carafate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have kidney problems or are on dialysis, or have blockage of the intestines or difficulty swallowing.

Some medicines may interact with Carafate. Tell your health care provider if you are taking any other medicines, especially any of the following:

Citrate salts or medicines that contain aluminum, specifically in patients with kidney disease, because side effects from aluminum buildup may occur.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Carafate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Carafate may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Take Carafate with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Carafate has aluminum in it. Before you start any new medicine, check the label to see if it has aluminum in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Carafate should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Carafate while you are pregnant. It is not known if Carafate is found in breast milk. If you are or will be breast-feeding while you take Carafate, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; dizziness; feeling of a whirling motion.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Enalapril Uses, Dosage, Side Effects, Lapril

Enalapril

What is enalapril?

Enalapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Enalapril is used to treat high blood pressure (hypertension) in adults and children who are at least 1 month old.

Enalapril is also used to treat congestive heart failure in adults.

Enalapril is also used to treat a disorder of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). This disorder can decrease the heart's ability to pump blood to the body.

Important information

Do not use enalapril if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Enalapril can cause injury or death to an unborn baby.

You should not use enalapril if you have ever had angioedema.

Enalapril can cause kidney problems. Call your doctor at once if you have swelling, rapid weight gain, little or no urinating, or if you feel short of breath.

If you have diabetes, do not use enalapril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

Enalapril can affect your heart or your electrolyte levels. Call your doctor if you have chest pain, pounding heartbeats or fluttering in your chest, a slow heart rate or weak pulse, a tingly feeling, muscle weakness, or muscle tightness or contraction.

Before taking this medicine

You should not use enalapril if you are allergic to it, or if you have:

a history of angioedema; or

if you are allergic to any other ACE inhibitor, such as benazepril, captopril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.

If you have diabetes, do not use enalapril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

You may also need to avoid taking enalapril with aliskiren if you have kidney disease.

To make sure enalapril is safe for you, tell your doctor if you have:

kidney disease (or if you are on dialysis);

a history of blood clot or stroke (including "mini-stroke";

an electrolyte imbalance (such as high levels of potassium in your blood); or

heart disease or congestive heart failure (unless you are taking enalapril for this condition).

Do not use enalapril if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant. Enalapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking this medication.

Enalapril can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

How should I take enalapril?

Take enalapril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take enalapril with or without food.

Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Your blood pressure will need to be checked often. Your kidney or liver function may also need to be tested.

You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.

If you need surgery, tell the surgeon ahead of time that you are using enalapril. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Store the liquid medicine in the refrigerator, do not freeze. Throw away any enalapril liquid not used within 60 days.

Enalapril dosing information

Usual Adult Dose for Hypertension:

Initial dose (oral tablets or solution): 5 mg orally once a day Maintenance dose (oral tablets or solution): 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses

In combination with diuretics: Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Parenteral: 1.25 to 5 mg IV over a 5 minute period every 6 hours

Comments: - Clinical response is usually seen within 15 minutes after IV administration. - If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses

Comments: - Treatment is usually combined with diuretics and digitalis. - Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses

Comments: - After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. - If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension:

Oral tablets or solution: Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients.

Comment: - Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking enalapril?

Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of enalapril.

Do not use salt substitutes or potassium supplements while taking enalapril, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Enalapril side effects

Get emergency medical help if you have any signs of an allergic reaction to enalapril . hives; severe stomach pain; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

pounding heartbeats or fluttering in your chest;

high potassium - slow heart rate, weak pulse, muscle weakness, tingly feeling;

low white blood cell counts - sudden weakness or ill feeling, fever, chills, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing; or

signs of a kidney problem - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath.

Common enalapril side effects may include:

dizziness, tired feeling;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect enalapril?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with enalapril, especially:

a diuretic or "water pill";

gold injections to treat arthritis;

medicine to prevent organ transplant rejection - everolimus, sirolimus, temsirolimus; or

NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may interact with enalapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

More about enalapril

Consumer resources

Professional resources

Related treatment guides

Where can I get more information?

Your pharmacist can provide more information about enalapril.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use enalapril only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 10.02. Revision Date: 2016-02-12, 3:59:07 PM.

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Fluidixine, Fluidixine

Common use It is is a broad-spectrum antibiotic which destroys bacteria. It is active against many aerobic (those developing in presence of oxygen) and anaerobic (those developing in absence of oxygen) gram positive and aerobic gram negative microorganisms including strains which produce beta-lactamase (the enzyme which destroys penicillin). Clavulanate potassium comprised in the content of this medication provides resistance of Augmentin to activity of bacterial beta-lactamases. This medication is used to treat pneumonia and other infectious diseases of respiratory, gastrointestinal systems, urogenital systems, infections which appear after surgery and others.

Dosage and directions Doses are administered individually depending on your condition, localization of infection and susceptibility of the pathogen. Do not take it in larger amounts or longer than recommended. Swallow the whole tablet. If it is the Augmentin Chewable tablet then chew it before swallowing. Augmentin should be taken at evenly spaced interval.

Precautions Do not use it if you are allergic to any other penicillin antibiotic, if you have liver or kidney failure or mononucleosis.

Contraindications Do not use the medicine if you have allergy to its components or another penicillin antibiotics, if you have infectious mononucleosis, a history of liver problems or yellowing of the eyes or skin caused by Augmentin.

Possible side effect Dyspepsia, abdominal discomfort, bloating, gas nausea, vomiting, liver function disorders, hepatitis, jaundice caused by stagnation of bile, vaginal itching and also symptoms of allergy (hives, rash, swelling). Cautiousness should be exercised in patients with liver failure. The medication is not recommended for pregnant (especially third trimester) and breastfeeding women.

Treatment with Augmentin and other antibiotics can change the normal bacteria flora of the colon and permit overgrowth of C. difficile, a bacteria which causes pseudomembranous colitis. Probenecid which is used to treat gout may slow excretion of Augmentin by kidneys and result in increase of its toxicity.

Missed dose If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to compensate a missed dose by taking an extra one.

Overdose If you suppose that took too much of Augmentin and experience such symptoms as nausea, vomiting, stomach pain, diarrhea, skin rash, drowsiness, and hyperactivity, seek immediate medical help.

Storage Store at room temperature of 59-86F (15-30C) away from light and moisture.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care advisor or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Common use It is is a broad-spectrum antibiotic which destroys bacteria. It is active against many aerobic (those developing in presence of oxygen) and anaerobic (those developing in absence of oxygen) gram positive and aerobic gram negative microorganisms including strains which produce beta-lactamase (the enzyme which destroys penicillin). Clavulanate potassium comprised in the content of this medication provides resistance of Augmentin to activity of bacterial beta-lactamases. This medication is used to treat pneumonia and other infectious diseases of respiratory, gastrointestinal systems, urogenital systems, infections which appear after surgery and others.

Dosage and directions Doses are administered individually depending on your condition, localization of infection and susceptibility of the pathogen. Do not take it in larger amounts or longer than recommended. Swallow the whole tablet. If it is the Augmentin Chewable tablet then chew it before swallowing. Augmentin should be taken at evenly spaced interval.

Precautions Do not use it if you are allergic to any other penicillin antibiotic, if you have liver or kidney failure or mononucleosis.

Contraindications Do not use the medicine if you have allergy to its components or another penicillin antibiotics, if you have infectious mononucleosis, a history of liver problems or yellowing of the eyes or skin caused by Augmentin.

Possible side effect Dyspepsia, abdominal discomfort, bloating, gas nausea, vomiting, liver function disorders, hepatitis, jaundice caused by stagnation of bile, vaginal itching and also symptoms of allergy (hives, rash, swelling). Cautiousness should be exercised in patients with liver failure. The medication is not recommended for pregnant (especially third trimester) and breastfeeding women.

Treatment with Augmentin and other antibiotics can change the normal bacteria flora of the colon and permit overgrowth of C. difficile, a bacteria which causes pseudomembranous colitis. Probenecid which is used to treat gout may slow excretion of Augmentin by kidneys and result in increase of its toxicity.

Missed dose If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to compensate a missed dose by taking an extra one.

Overdose If you suppose that took too much of Augmentin and experience such symptoms as nausea, vomiting, stomach pain, diarrhea, skin rash, drowsiness, and hyperactivity, seek immediate medical help.

Storage Store at room temperature of 59-86F (15-30C) away from light and moisture.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care advisor or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Hydrazide - Definition Of Hydrazide By The Free Dictionary, Hydrazide

hydrazide

The government will supply the drugs to designated chemists and will also give them incentives for distributing four drugs including Isonicotinic Hydrazide ( INH).

Scientists can study glycosylated proteins by breaking apart cells, then using agarose beads coated with hydrazide molecules to attract the glycans and therefore their associated proteins.

tuberculosis with in vitro resistance to two first-line medications: ionized (isonicotinic acid hydrazide. INH) and rifampin (RIF).

5% azo and hydrazide active ingredients in a universal carrier permit letdowns from 100:1 to 40:1.

23] who reported maximum fruit yield in watermelon with an application of maleic hydrazide at 100 ppm.

Synthesis and biological evaluation of pyridine hydrazide derivatives.

is a polymer bead with dense hydrazide groups which enables selective purification of sugars, forming a reversible covalent bond.

Design, synthesis and biological evaluation of 4-benzamidobenzoic acid hydrazide derivatives as novel soluble epoxide hydrolase inhibitors.

The Eastman Student Poster Award Undergraduate Recipients are Laken Kendrick, "Design of Biomimetic Adhesives for Improved Wet Adhesion;" Chase Tretbar, "Synthesis of Hydrazide Functional Polymers by RAFT Polymerization;" Christopher Keller, "The Effect of Counter-Ion Exchange on the Morphology and pH Tunability of AB poly(butadiene)b-poly(lysine) Diblock Copolymers;" and Chase Thompson, "Analysis of the Formation of the DGEVF/4,4'-DDS Crosslink Network as a Function of a Cure Rate.

p, p'-Oxybis benzene sulfonyl hydrazide (OBSH) blowing agent is used and provided by Chemtura[R].

com)-- AnaSpec is pleased to announce the launch of the first commercially available Amino Acid Pre-loaded Hydrazide Resins.

Substrate hydrolysis was measured by the liberation of reducing sugars using the p-hydroxybenzoic acid hydrazide colorimetric analysis of Lever (1972) adapted to a multiwall plate format.

Metoclopramide - Brand Name List From, Irtopan

Metoclopramide

See also.

Disclaimer: The indications, uses and warnings for individual medications outside the USA are determined by local regulatory bodies in each country or region. The Drugs. com website is intended primarily for audiences in the United States and its territories. Indications, uses and warnings on Drugs. com patient information leaflets are derived from FDA product labels and may differ in countries outside the USA. Every effort has been made to ensure that the information provided on this page is accurate, up-to-date and complete, but no guarantee is made to that effect. Drugs. com does not endorse drugs, diagnose patients or recommend specific therapies. The information on this page is not a substitute for the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that a drug or drug combination is safe, effective or appropriate for any given patient. Drugs. com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Always consult your doctor or healthcare specialist for medical advice.

Chemical formula: C14H22ClN3O2 Drugbank ID: DB01233 ATC code(s): A03FA01

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Tegretol - Pain Relief, Karbalex

Tegretol (carbamazepine) is an anticonvulsant. It works by decreasing nerve impulses that cause seizures and pain. Tegretol is used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy. Carbamazepine is also used to treat bipolar disorder. Tegretol may also be used for purposes not listed in this medication guide.

Take Tegretol exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release Tegretol tablet. Swallow the pill whole. Breaking the pill would cause too much of the drug to be released at one time.

Shake the Tegretol oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and call your doctor promptly if this medicine seems to stop working as well in preventing your seizures. Tegretol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill.

To be sure Tegretol is not causing harmful effects, your blood cells and kidney function may need to be tested often. Do not miss any follow up visits to your doctor for blood or urine tests. Your doctor may also recommend having your eyes checked regularly while you are taking this medicine.

Do not stop using Tegretol without first talking to your doctor, even if you feel fine. You may have increased seizures or unpleasant withdrawal symptoms if you stop using this medicine suddenly. Wear a medical alert tag or carry an ID card stating that you take Tegretol. Any medical care provider who treats you should know that you take seizure medication.

Store this medicine at room temperature away from moisture, heat, and light.

Active Ingredient: Carbamazepine

Tegretol may cause severe or life-threatening skin rash, especially in people of Asian ancestry. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction. Seek emergency medical attention if you have a fever, sore throat, headache and skin pain, followed by a red or purple skin rash that spreads and causes blistering and peeling.

You should not take Tegretol if you have a history of bone marrow suppression, if you are also taking nefazodone, or if you are allergic to an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor).

Tegretol may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant while taking Tegretol for seizures. Do not start or stop taking Tegretol during pregnancy without your doctor's advice.

Before you take Tegretol, tell your doctor if you have heart disease, high blood pressure, high cholesterol, liver or kidney disease, glaucoma, a thyroid disorder, lupus, porphyria, or a history of mental illness or psychosis.

You may have thoughts about suicide while taking Tegretol. Your doctor will need to check you at regular visits. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

There are many other drugs that can interact with Tegretol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Do not stop using Tegretol without first talking to your doctor, even if you feel fine. You may have increased seizures or unpleasant withdrawal symptoms if you stop using Tegretol suddenly.

Do not use Tegretol if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. You should not take Tegretol if you are allergic to carbamazepine, or if you have:

a history of bone marrow suppression

if you are also taking nefazodone; or

if you are allergic to an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor).

Important safety information:

Tegretol may cause severe or life-threatening skin rash, especially in people of Asian ancestry. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction.

To make sure you can safely take Tegretol, tell your doctor if you have any of these other conditions:

heart disease, high blood pressure, high cholesterol or triglycerides;

liver or kidney disease;

a thyroid disorder;

a history of mental illness or psychosis.

Patients of Asian ancestry may have a higher risk of developing a rare but serious skin reaction to Tegretol. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

You may have thoughts about suicide while taking Tegretol. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed. Seizure control is very important during pregnancy. The benefit of preventing seizures may outweigh any risks posed by taking Tegretol. Follow your doctor's instructions about taking Tegretol while you are pregnant.

FDA pregnancy category D. Tegretol may cause harm to an unborn baby. Do not start taking this medcine without telling your doctor if you are pregnant or planning to become pregnant. Use effective birth control while you are taking this medicine. Although Tegretol may harm an unborn baby, having a seizure during pregnancy could harm both mother and baby. If you become pregnant while taking Tegretol, do not stop taking the medicine without your doctor's advice.

Carbamazepine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using Tegretol. Carbamazepine can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking Tegretol.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid drinking alcohol. It can increase some of the side effects of Tegretol, and can also increase your risk of seizures.

Avoid exposure to sunlight or tanning beds. Tegretol can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Grapefruit and grapefruit juice may interact with Tegretol and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction to Tegretol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

pale skin, feeling light-headed, rapid heart rate, trouble concentrating;

fever, chills, sore throat, mouth and throat ulcers;

easy bruising or bleeding, severe tingling, numbness, pain, muscle weakness;

confusion, agitation, vision problems, hallucinations;

feeling short of breath, swelling of your ankles or feet;

urinating less than usual;

jaundice (yellowing of the skin or eyes); or

severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious Tegretol side effects may include:

feeling dizzy, drowsy, or unsteady;

nausea, vomiting, diarrhea, constipation, stomach pain;

headache, ringing in your ears;

dry mouth, swollen tongue; or

joint or muscle pain, leg cramps.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Thu?c Kefcin, Kefcin

Kefcin

CÔNG TH?C: Cefaclor. 125 mg Tá du?c v?a d?. 1 gói (Sacarose, mùi dâu, natri lauryl sulphat, methylcellulose, màu d? erythrosin, propylen glycol).

D?NG BÀO CH?: Thu?c b?t.

DÓNG GÓI: H?p 25 gói x 3g.

CH? D?NH: Di?u tr? nhi?m trùng du?ng hô h?p trên và du?i (viêm h?ng, viêm amidan, viêm ph? qu?n, viêm ph?i ), viêm xoang, viêm tai gi?a, nhi?m trùng da và mô m?m, nhi?m trùng du?ng ti?u . CH?NG CH? D?NH: M?n c?m v?i Cephalosporin và Penicilin

TH?N TR?NG: Suy th?n n?ng, suy ch?c nang gan. Có ti?n s? b?nh du?ng tiêu hoá nhu viêm d?i tràng. Ph? n? có thai và cho con bú. Tr? em du?i 1 tháng tu?i.

Write Your Own Review

Demo Website. Thong tin thu?c ch? mang tinh ch?t tham kh?o - Khi dung thu?c c?n tuy?t d?i tuan theo hu?ng d?n c?a Bac si. Web dang xay d?ng. Ban ho?c h?p tac & d?u tu.

Grysio Indication, Action Of Grysio, Interactions, Grysio

Grysio [in more detail]

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Grysio Mechanism Of Action:

Grysio is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis and nuclear acid synthesis. It also binds to and interferes with the function of spindle and cytoplasmic microtubules by binding to alpha and beta tubulin.

Grysio Drug Interactions:

Amobarbital The barbiturate decreases the effect of griseofulvin Aprobarbital The barbiturate decreases the effect of griseofulvin Butalbital The barbiturate decreases the effect of griseofulvin Butabarbital The barbiturate decreases the effect of griseofulvin Butethal The barbiturate decreases the effect of griseofulvin Dihydroquinidine barbiturate The barbiturate decreases the effect of griseofulvin Heptabarbital The barbiturate decreases the effect of griseofulvin Hexobarbital The barbiturate decreases the effect of griseofulvin Methohexital The barbiturate decreases the effect of griseofulvin Methylphenobarbital The barbiturate decreases the effect of griseofulvin Talbutal The barbiturate decreases the effect of griseofulvin Secobarbital The barbiturate decreases the effect of griseofulvin Quinidine barbiturate The barbiturate decreases the effect of griseofulvin Primidone The barbiturate decreases the effect of griseofulvin Phenobarbital The barbiturate decreases the effect of griseofulvin Pentobarbital The barbiturate decreases the effect of griseofulvin Warfarin Grysio decreases the anticoagulant effect Acenocoumarol Grysio decreases the anticoagulant effect Dicumarol Grysio decreases the anticoagulant effect Anisindione Grysio decreases the anticoagulant effect Aspirin Anticipate decrease of ASA efficiency in presence of griseofulvin Chlorotrianisene The enzyme inducer decreases the effect of the hormones Clomifene The enzyme inducer decreases the effect of the hormones Cyclosporine Grysio decreases the effect of cyclosporine Diethylstilbestrol The enzyme inducer decreases the effect of the hormones Estradiol The enzyme inducer decreases the effect of the hormones Estriol The enzyme inducer decreases the effect of the hormones Conjugated Estrogens The enzyme inducer decreases the effect of the hormones Estrone The enzyme inducer decreases the effect of the hormones Estropipate The enzyme inducer decreases the effect of the hormones Medroxyprogesterone The enzyme inducer decreases the effect of the hormones Megestrol The enzyme inducer decreases the effect of the hormones Ethinyl Estradiol This product may cause a slight decrease of contraceptive effect Quinestrol The enzyme inducer decreases the effect of the hormones Mestranol This product may cause a slight decrease of contraceptive effect Norethindrone This product may cause a slight decrease of contraceptive effect

Food Interactions:

Take this medication with a high fat meal, fatty foods increase bioavailability. Avoid alcohol.

Grysio Chemical Formula:

Ciprin, Ciprin

PROPRIETARY NAME (and dosage form):

ADCO-CIPRIN 250 mg (Tablets) ADCO-CIPRIN 500 mg (Tablets) ADCO-CIPRIN 750 mg (Tablets)

COMPOSITION: Adco-Ciprin 250 mg Each film coated tablet contains Ciprofloxacin hydrochloride equivalent to ciprofloxacin 250 mg

Adco-Ciprin 500 mg Each film coated tablet contains Ciprofloxacin hydrochloride equivalent to ciprofloxacin 500 mg

Adco-Ciprin 750 mg Each film coated tablet contains Ciprofloxacin hydrochloride equivalent to ciprofloxacin 750 mg

PHARMACOLOGICAL CLASSIFICATION: A 20.1.1 Broad and medium spectrum antibiotics

MECHANISM OF ACTION Fluoroquinolones bring about their bactericidal action by inhibiting the bacterial DNA gyrase enzyme. DNA gyrase is responsible for continuous introduction of negative supercoils into DNA. This is an ATP dependent reaction that requires both strands of the DNA to be cut to permit passage of a segment of DNA through the break; the break is then resealed. Fluoroquinolones decrease the introduction of negative supercoils into DNA and cause rapid cessation of DNA synthesis by interfering with the propagation of DNA replication. Antibacterial Spectrum The antibacterial spectrum of ciprofloxacin includes Gram-negative and Gram-positive organisms viz. Acinetobacter, Aeromonas, Campylobacter jejuni, Citrobacter freundii. Citrobacter species, Corynebacterium, Edwardsiella, Enterobacter cloacae, Enterobacter species, Listeria, Morganella morganii, E. coli, Klebsiella spp. Salmonella enteritidis. P. mirabilis, P. vulgaris, Yersinia, Ps. aeruginosa, Shigella flexneri, Shigella sonnei, Hafnia, H. influenzae, H. para-influenzae, N. gonorrhoeae, M. catarrhalis, Vibrio, Staph. aureus (including methicillin resistant strains), Staph. epidermidis, Strep. pyogenes, Strep. species, Brucella, Pasteurella, Plesiomonas, Providencia rettgeri, Providencia stuartii, Serratia marcescens. In vitro sensitivity does not necessarily imply in vivo efficacy. The following organisms show varying degrees of in vitro sensitivity to ciprofloxacin. Alcaligenes, Enterococcus faecalis, Flavobacterium, Gardnerella, Legionella, Mycobacterium fortuitum, Mycobacterium tuberculosis, Mycoplasma hominis, Streptococcus agalactiae, Chlamydia . The following are usually resistant: Enterococcus faecium, Ureaplasma urealyticum, Nocardia asteroides. With a few exceptions anaerobes are moderately sensitive (e. g. Peptococcus . Peptostreptococcus ) to resistant (e. g. Bacteriodes . Treponema pallidium ). Pharmacokinetics Ciprofloxacin is well absorbed when given orally with a bioavailability of 70%. The mean peak plasma concentrations achieved after oral administration of 250 mg, 500 mg and 750 mg of ciprofloxacin are 1.2 mcg/mL, 2.4 mcg/mL and 4.3 mcg/mL respectively, achieved within 1-2 hours of administration. Absorption is delayed when ciprofloxacin is given with a meal. Plasma protein binding ranges from 20 to 40%. Ciprofloxacin is widely distributed throughout the body viz. lung, skin, fat, muscle, cartilage, bone and genital tissues including the prostate. It is present in active form in saliva, nasal and bronchial secretions, sputum, skin blister fluid, lymph, peritoneal fluid, bile and prostatic secretions. Ciprofloxacin is partly metabolised in the liver. About 50% of an oral dose is recovered unchanged in the urine and 15% as active metabolites viz. oxociprofloxacin. The rest undergoes biliary excretion and transluminal secretion across the intestinal mucosa. The plasma elimination half-life is about 3.5 - 4.5 hrs. The half-life may be prolonged in severe renal insufficiency and in the elderly.

INDICATIONS: Ciprofloxacin is indicated for the treatment of the following infections caused by ciprofloxacin sensitive bacteria: Lower Respiratory Tract Infections caused by Escherichia coli . Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis, Pseudomonas aeruginosa, Haemophilus influenzae and Haemophilus para-influenzae . Urinary Tract Infections caused by Escherichia coli . Klebsiella pneumoniae . Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Providencia rettgeri, Morganella morganii, Citrobacter diversus, Citrobacter freundii, Pseudomonas aeruginosa, Staphylococcus epidermidis and Streptococcus faecalis . Skin and Soft Tissue Infections caused by Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis, Proteus vulgaris, Providencia stuartii, Morganella morganii, Citrobacter freundii, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus pyogenes. Gastro-intestinal Infections: Infective diarrhoea caused by E. coli . Campylobacter jejuni . Shigella flexneri and Shigella sonnei . Bone Infections: Osteomyelitis due to susceptible gram-negative organisms. Gonorrhoea: Ciprofloxacin is ineffective against Treponema pallidum . In the treatment of infections caused by Pseudomonas aeruginosa . an aminoglycoside must be administered concomitantly.

CONTRA-INDICATIONS Safety during pregnancy and lactation has not been established.

Ciprofloxacin is contra-indicated in children under 18 years and in growing adolescents, except where the benefits of treatment exceed the risks. Experimental evidence indicates that, species variable, reversible lesions of the cartilage of weight bearing joints has been seen in immature members of certain animal species.

Ciprofloxacin is contra-indicated in patients who have shown hypersensitivity to ciprofloxacin or any other quinolones.

Ciprofloxacin should be used with caution in patients with a history of convulsive disorders. Crystalluria related to the use of ciprofloxacin has been observed. Patients receiving ciprofloxacin should be well hydrated and excessive alkalinity of the urine should be avoided.

DOSAGE AND DIRECTIONS FOR USE: Ciprofloxacin tablets should be swallowed whole with plenty of liquid and may be taken with or without meals. Dosage and duration of treatment . The dosage range is 250-750 mg twice daily. The duration of treatment depends upon the severity of the infection, clinical respone and bacteriological findings. For acute uncomplicated cystitis in women, the treatment period is 3 days. Generally, treatment should be continued for at least 3 days after the signs and symptoms of the infection have disappeared. For acute infections the usual treatment period is 5 to 10 days with ciprofloxacin tablets. For severe and complicated infections more prolonged therapy may be required. In streptococcal infections the treatment must last at least 10 days because of the risk of late complications. Infections of the lower respiratory tract . Mild to moderate - 250 to 500 mg twice daily; severe or complicated - 750 mg twice daily. In cystic fibrosis patients the dose is 750 mg twice daily. The low body mass of these patients should, however, be taken into consideration when determining dosage (7.5 to 15 mg/kg/day). Infectious diarroea . 500 mg twice daily. Infections of the urinary tract . Acute uncomplicated cystitis - 250 mg twice daily; mild to moderate - 250 mg twice daily; severe or complicated - 500 mg twice daily. Infections of the skin . Mild to moderate - 500 mg twice daily; severe or complicated - 750 mg twice daily. Bone infections . Mild to moderate 500 mg twice daily; severe or complicated-750 mg twice daily. Treatment may be required for 4-6 weeks or longer. Gonorrhoea . A single dose of 250 mg.

Elderly patients should receive a dose as low as possible; this will depend on the severity of the illness and on the creatinine clearance.

Impaired renal or liver function . In patients with reduced renal function, the half-life of ciprofloxacin is prolonged and the dosage needs to be adjusted. For patients with changing renal function or patients with renal impairment and hepatic insufficiency, monitoring of drug serum levels provides the most reliable basis for dose adjustment.

Dose adjustment of ciprofloxacin for patients with kidney and/or liver insufficiency:

Liver and kidney insufficiency:

As in 1.1 and 1.2 above

SIDE-EFFECTS AND SPECIAL PRECAUTIONS: The following side-effects have been observed: Effects on the gastro-intestinal tract: Nausea, diarrhoea, vomiting, dyspepsia, abdominal pain, flatulence, anorexia. In the event of severe and persistent diarrhoea during or after treatment, a doctor must be consulted since this symptom can hide a serious intestinal disease (pseudomembranous colitis), requiring immediate treatment. In such cases ciprofloxacin must be discontinued and appropriate therapy initiated (e. g. vancomycin, orally, 4 x 250 mg/day). Drugs that inhibit peristalsis are contraindicated. Effects on the nervous system: Dizziness, headache, tiredness, nervousness, agitation, trembling. Infrequently: insomnia, peripheral paralgesia, sweating, unsteady gait, convulsions, increase in intracranial pressure, anxiety states, nightmares, confusion, depression, hallucinations, in individual cases psychotic reactions (even progressing to self endangering behaviour). In some instances, these reactions occurred already after the first administration of ciprofloxacin. In these cases ciproflxoacin has to be discontinued and the doctor should be informed immediately. Reactions of sensory organs: Impaired taste and smell, visual disturbances (e. g. diplopia, colour vision), tinnitus, transitory impairment of hearing, especially at high frequencies. Hypersensitivity reactions: Skin reactions, e. g. rashes, pruritus, drug fever. Infrequently: Punctate skin haemorrhages (petechiae), blister formation with accompanying haemorrhages (haemorrhagic bullae) and small nodules (papules) with crust formation showing vascular involvement (vasculitis). Erythema nodosum, Erythema exudativum multiforme (minor), Stevens Johnson Syndrome, Lyell Syndrome. Intestitial nephritis, hepatitis, hepatic necrosis very seldom progressing to life-threatening hepatic failure. Anaphylactic/anaphylactoid reactions (e. g. facial, vascular and laryngeal oedema, dyspnoea progressing to life-threatening shock), in some instances after the first adminsitration. In these cases ciprofloxacin has to be discontinued and medical treatment (e. g. treatment for shock) is required. Effects on the cardiovascular system: Tachycardia, hot flushes, migraine, fainting. Other side effects: Joint pain, joint swelling. Very rarely: general feeling of weakness, muscular pains, tendosynovitis, photosensitivity, transient impairment in kidney function including transient kidney failure. In single cases during the administration of ciprofloxacin, achillotendinitis was observed. Cases of partial or complete rupture of the achilles tendon have been reported predominantly in the elderly on prior systemic treatment with glucocorticoids. Therefore, at any signs of an achillotendinitis (e. g. painful swelling) the administration of ciprofloxacin should be discontinued and a physician be consulted. Long-term or repeated administration of ciprofloxacin can lead to superinfections with resistant bacteria or yeast-like fungi. Effects on the blood and blood constituents: Eosinophilia, leucocytopenia, granulocytopenia, anaemia, thrombocytopenia. Very rarely: leucocytosis, thrombocytosis, haemolytic anaemia, altered prothrombin values. Influence on laboratory parameters/urinary sediment: There can be a temporary increase in transaminases, alkaline phosphatase or cholestatic jaundice, especially in patients with previous liver damage; temporary increase in urea, creatinine or bilirubin in the serum; in individual cases hyperglycaemia, crystalluria or haematuria. Other Information: Even when the medicine is taken as prescribed, it can affect the speed of reaction to such an extent that the ability to drive or to operate machinery is impaired. This applies particularly in combination with alcohol.

Interactions: Concurrent administration of ciprofloxacin with theophylline may lead to elevated plasma concentrations of theophylline and prolongation of its elimination half-life. This may result in increased risk of theophylline-related adverse reactions. If concomitant use cannot be avoided, plasma levels of theophylline should be monitored and dosage adjustments made as appropriate. Ciprofloxacin tablets should be administered 1-2 hours before, or at least 4 hours after taking iron preparations, antacids containing magnesium, aluminium, calcium or sucralfate as interference with absorption may occur. This restriction does not apply to antacids belonging to the class of H 2 receptor blockers. Concomitant-administration of the nonsteroidal anti-inflammatory drug fenbufen with quinolones has been reported to increase the risk of central nervous system stimulation and convulsive seizures. Monitoring of serum creatinine concentrations is advised in patients on concomitant cyclosporin therapy, as transient increases in serum creatinine concentrations have been observed. The simultaneous administration of ciprofloxacin and warfarin may intensify the action of warfarin. In particular cases, concurrent administration of ciprofloxacin and glibenclamide can intensify the action of glibenclamide (hypoglycaemia). Probenecid interferes with renal secretion of ciprofloxacin. Co-administration of probenecid and ciprofloxacin increases the ciprofloxacin serum concentrations. Metoclopramide accelerates the absorption of ciprofloxacin, resulting in a shorter time to reach maximum plasma concentrations. No effect was seen on the bioavailability of ciprofloxacin.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT In the event of acute, excessive oral overdosage, reversible renal toxicity has been reported. Therefore, apart from routine emergency measures, it is recommended to monitor renal function and to administer Mg or Ca-containing antacids which reduce the absorption of ciprofloxacin. Only a small amount of ciprofloxacin (<10%) is removed from the body after haemodialysis or peritoneal dialysis. Treatment should be symptomatic and supportive.

IDENTIFICATION: Adco-Ciprin 250 mg: White, round, film-coated tablets embossed with `250' on one side and plain on the other side, with intact coating. Adco-Ciprin 500 mg: White caplet shaped, film-coated tablets embossed with `500' on one side and plain on other other side, with intact coating. Adco-Ciprin 750 mg: White caplet shaped, film-coated tablets embossed with `750' on one side and plain on other other side, with intact coating.

PRESENTATION: Adco-Ciprin 250 mg: Carton containing blister strip of 10 tablets Adco-Ciprin 500 mg: Carton containing blister strip of 10 tablets Adco-Ciprin 750 mg: Carton containing blister strip of 10 tablets

STORAGE INSTRUCTIONS: Store below 25°C, protected from moisture. KEEP OUT OF REACH OF CHILDREN.

REGISTRATION NUMBERS: Adco-Ciprin 250 mg: 33/20.1.1/0371 Adco-Ciprin 500 mg: 33/20.1.1/0372 Adco-Ciprin 750 mg: 33/20.1.1/0373

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DATE OF PUBLICATION OF THIS PACKAGE INSERT: July 1999

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Endopryl (Eldepryl) Description

Endopryl is a medication which prevents the breakdown of a chemical in your brain.

Endopryl is used to treat Parkinson's disease.

Endopryl is also known as Selegiline.

Endopryl prevents the breakdown of a chemical in your brain called dopamine, thereby prevents Parkinson's disease.

Generic name of Endopryl is Selegiline.

Brand names of Endopryl are Endopryl, Zelapar.

Endopryl (Eldepryl) Dosage

Endopryl is available in:

Take Endopryl orally.

Take Endopryl capsules twice a day, at breakfast and lunch.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Do not drink or eat anything for at least 5 minutes after takink Endopryl.

While using Endopryl, you must not eat foods that are high in tyramine such as air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver; beer from a tap, beer that has not been pasteurized; aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss; sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; yeast extracts (such as Marmite).

Preferable food during Endopryl usage are fresh meat, poultry, or fish (including lunch meat, hot dogs, breakfast sausage, and cooked sliced ham); any vegetables except broad bean pods (fava beans); processed cheese, mozzarella, ricotta, cottage cheese; pizza made with cheeses low in tyramine; soy milk, yogurt.

If you want to achieve most effective results do not stop taking Endopryl suddenly.

Endopryl (Eldepryl) Missing of dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Endopryl (Eldepryl) Overdose

If you overdose Endopryl and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Endopryl overdosage: severe headache, hallucinations, vision problems, sweating, cool or clammy skin, fast or uneven heart rate, feeling light-headed, fainting, seizure.

Endopryl (Eldepryl) Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Endopryl (Eldepryl) Side effects

Endopryl has its side effects. The most common are:

dizziness

weakness

insomnia

runny or stuffy nose

back pain

constipation

Less common but more serious side effects during taking Endopryl:

allergy reactions (urticaria, breathing difficulties, rash, and eruption)

sudden and severe headache

confusio

blurred vision

problems with speech or balance

nausea

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chest pain

convulsions

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painful or difficult urination

twitching muscle movements

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Endopryl (Eldepryl) Contra-indications

Do not take Endopryl if you are allergic to Endopryl components.

Do not take Endopryl if you are pregnant, planning to become pregnant or breast-feeding.

Be careful using Endopryl if you have kidney disease, liver disease, heart disease, high or low blood pressure, seizure disorder.

Be careful using Endopryl if you take over-the-counter medications you use, including vitamins, minerals, and herbal products, carbamazepine (Tegretol), diet pills or cold medicines that contain ephedrine, pseudoephedrine or phenylephrine, nafcillin (Unipen), phenobarbital (Luminal, Solfoton), rifampin (Rifadin, Rifater, Rifamate, Rimactane), antidepressants such as amitriptyline (Elavil), amoxapine (Ascendin), bupropion (Wellbutrin, Zyban), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), venlafaxine (Effexor) or trimipramine (Surmontil).

While using Endopryl, you must not eat foods that are high in tyraminesuch as air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver; beer from a tap, beer that has not been pasteurized; aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss; sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; yeast extracts (such as Marmite).

Do not take Endopryl if you use over-the-counter supplements or cough and cold medicines that contain tyramine.

It can be dangerous to stop Endopryl taking suddenly.

Endopryl (Eldepryl) Frequently asked questions

Q: What is Endopryl?

A: Endopryl is a medication which prevents the breakdown of a chemical in your brain.

Q: What Endopryl is used for?

A: Endopryl is used to treat Parkinson's disease.

Q: How does Endopryl work?

A: Endopryl prevents the breakdown of a chemical in your brain called dopamine, thereby prevents Parkinson's disease.

Q: What should I do in case of dose missing?

A: In case of dose missing you should take your tablet as soon as possible. Do not take double dosage. And if it is right time for the next dosage you should continue your regular schedule of Generic Eldepyl taking.

Q: Are there any food limitation while Endopryl usage?

A: While using Endopryl, you must not eat foods that are high in tyramine such as air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver; beer from a tap, beer that has not been pasteurized; aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss; sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; yeast extracts (such as Marmite).

Q: Are there any allergic reactions on Endopryl?

A: Allergic reactions on Endopryl: hives; difficulty breathing; swelling of your face, lips, tongue or throat.

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Uritas Indication

For the treatment of hyperuricemia associated with primary or secondary gout.

Uritas Pharmacology

Allopurinol, a structural analog of the natural purine base hypoxanthine, is used to prevent gout and renal calculi due to either uric acid or calcium oxalate and to treat uric acid nephropathy, hyperuricemia, and some solid tumors.

Uritas Absorption

Approximately 90% absorbed from the gastrointestinal tract.

Uritas side effects and Toxicity

LD 50 =214 mg/kg (in mice)

Uritas Patient Information

Patients should be informed of the following:

1 . They should be cautioned to discontinue allopurinol and to consult their physician immediately at the first sign of a skin rash, painful urination, blood in the urine, irritation of the eyes, or swelling of the lips or mouth. 2. They should be reminded to continue drug therapy prescribed for gouty attacks since optimal benefit of allopurinol may be delayed for two to six weeks. 3. They should be encouraged to increase fluid intake during therapy to prevent renal stones. 4. If a single dose of allopurinol is occasionally forgotten, there is no need to double the dose at the next scheduled time. 5. There may be certain risks associated with the concomitant use of allopurinol and dicumarol, sulfinpyrazone, mercaptopurine, azathioprine, ampicillin, amoxicillin and thiazide diuretics, and they should follow the instructions of their physician. 6. Due to the occasional occurrence of drowsiness, patients should take precautions when engaging in activities where alertness is mandatory. 7. Patients may wish to take allopurinol after meals to minimize gastric irritation.

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One last question, that acctually doesn't belong in this thread. Ooops.

Since I have got an evaluation copy of WHS, what happens when it expires?

There wasn't any info about that when I received it and I can't find any info about it on the website.

I mean, if I keep putting stuff onto the server for the next 120 days, like I'm doing now. My god, it'll kill me if I can't keep it and MS can charge me any price they want ;-)

Monday, April 14, 2008 6:33 PM

Answers

I've split this thread so it is it's own topic. You will need to purchase a copy of Windows Home Server, boot from the DVD and select Server Reinstallation. It will do a Server Reinstallation which should keep all of your DATA and Backups. After it's complete, you will need to redo all of your settings, (Remote Access, User names, Add-ins, etc. ).

Please make backups of your data before doing a Server Reinstallation. There is a risk you can lose data if something happens during the Reinstallation.

Monday, April 14, 2008 6:42 PM

All replies

I've split this thread so it is it's own topic. You will need to purchase a copy of Windows Home Server, boot from the DVD and select Server Reinstallation. It will do a Server Reinstallation which should keep all of your DATA and Backups. After it's complete, you will need to redo all of your settings, (Remote Access, User names, Add-ins, etc. ).

Please make backups of your data before doing a Server Reinstallation. There is a risk you can lose data if something happens during the Reinstallation.

Monday, April 14, 2008 6:42 PM

Thank you for your fast answer.

Since I just installed WHS, I am a little bit unsure what to do now.

I don't have a problem in purchase it, but I wanted to try it out first. I just thought that maybe you could just put in a new cd-key later that could be bought of MS and all would be good.

But now I'm thinking maybe buy it before using it, and then don't have to worry about anything. Because there's alot I want to install and all that needs to be done again.

The sh#tty thing is that it hasn't been realesed in Swedish just yet, and I was hoping to try it out first.

Don't mind having it in English. But I don't understand why it has to be done so complicated when we are acctually the ones that DON'T use pirate copies. So why not make it easy for us.

Tuesday, April 15, 2008 8:09 PM

Mupirocin Topical Uses, Side Effects, Interactions, Pictures, Warnings - Dosing, Mupirocinum

mupirocin topical

Uses

Mupirocin is used to treat certain skin infections (such as impetigo ). It is an antibiotic. It works by stopping the growth of certain bacteria.

How to use mupirocin topical

Read the Patient Information Leaflet if available from your pharmacist before you start using mupirocin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Use this medication only on the skin. Clean and dry the affected area first. Then apply a small amount of ointment to the area as directed by your doctor, usually 3 times a day. You may cover the treated area with a bandage.

Use this medication regularly to get the most benefit from it. Continue to use it for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Avoid using this medication around your eyes. nose, mouth. or on large areas of damaged or broken skin unless otherwise directed by your doctor. If you accidentally get it in your eyes. nose, or mouth. rinse well with plenty of water.

Tell your doctor if your condition does not get better in 3 to 5 days.

Side Effects

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Although uncommon, mild burning or stinging after using this medication may occur. If you have severe burning, stinging, or irritation, stop using this medication and tell your doctor right away.

This medication may rarely cause a severe intestinal condition (Clostridium difficile - associated diarrhea ) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain /cramping, blood /mucus in your stool.

Do not use anti-diarrhea products or narcotic pain medications if you have any of these symptoms because these products may make them worse.

Use of this medication for prolonged or repeated periods may result in a new skin infection caused by fungus or yeast. Tell your doctor right away if you notice signs of a new infection, or if your current infection does not get better or if it gets worse.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash. itching /swelling (especially of the face/tongue /throat), severe dizziness. trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www. fda. gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using mupirocin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as polyethylene glycol found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease (if you are using a brand of mupirocin that contains polyethylene glycol).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy. this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast - feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor directs you to do so. A different medication may be necessary in that case.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised December 2015. Copyright(c) 2015 First Databank, Inc.

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Interactions, Usage, Facts, And Information On Didronel Pmo, Didronel Pmo

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Aciclovir 200mg Tablets, Aciclovirum

ACICLOVIR 200MG TABLETS

Transcript

Patient Information Leaflet ACICLOVIR 200mg, 400mg, 800mg TABLETS Read all of this leaflet carefully before you start taking this medicine. • Keep this leaflet. You may need to read it again. • If you have any further questions, ask your doctor or pharmacist. • This medicine has been prescribed only for you. Do not pass it to others. It may harm them, even if their symptoms are the same as yours. • If any of these side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. In this leaflet 1. What are Aciclovir Tablets and what they are used for 2. Before you take Aciclovir Tablets 3. How to take Aciclovir Tablets 4. Possible side effects 5. How to store Aciclovir Tablets 6. Further information 1. WHAT ARE ACICLOVIR TABLETS ANDWHAT THEY ARE USED FOR The name of your medicine is Aciclovir 200mg, 400mg, 800mg Tablets (called aciclovir in this leaflet). Each tablet contains either 200mg, 400mg or 800mg of the active ingredient, aciclovir. Aciclovir belongs to a group of medicines called anti-virals. Aciclovir can be used: • To treat herpes and other viral infections caused by the herpes virus (varicella zoster) such as chicken pox and shingles • To prevent recurrent attacks of herpes simplex • To help prevent those who have low immune systems from getting herpes infections. 2. BEFORE YOU TAKE ACICLOVIR TABLETS DO NOT take Aciclovir and tell your doctor if: • You are allergic (hypersensitive) to aciclovir, valaciclovir or any other ingredients in these tablets (see section 6: further information). An allergic reaction can include a rash, itching, shortness of breath. Do not take this medicine if any of the above apply to you, talk to your doctor or pharmacist before taking aciclovir. Take special care with Aciclovir Before you take aciclovir, tell your doctor if: • You have kidney or liver disease • You are thirsty. You must be sure you drink plenty of “liquids such as water” whilst taking this medicine • You are an elderly patient. If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before using aciclovir. Taking other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines brought without a prescription, including herbal medicines. In particular, tell your doctor if you are taking any of the following medicines: • Probenecid – used for gout • Cimetidine – used for stomach acid • Mycophenolate mofetil – used after transplant operations. Tests Tell your doctor you are taking this medicine if you are going to have any blood or urine tests.

Pregnancy and breast feeding Talk to your doctor before taking this medicine if you are pregnant, planning to become pregnant or are breast feeding. Driving and using machines Some side effects such as drowsiness and sleepiness may impair your ability to concentrate and react. Make sure you are not affected before you drive or operate machinery. 400mg, 800mg TABLETS Take this medicine as your doctor or pharmacist has told you. Look on the label and ask the doctor or pharmacist if you are not sure. 3. How to take Aciclovir Tablets Taking this medicine • Each Tablet contains either 200mg, 400mg or 800mg Aciclovir • Take these tablets by mouth • Drink plenty of liquids such as water while taking this medicine • If you feel the effect of your medicine is too strong or too weak, do not change the dose yourself, but talk to your doctor or pharmacist. The usual doses are given below. These may be changed by your doctor: Adults: Usually you will be given 200mg tablets, but your doctor may give you a higher dose such as 400mg or 800mg tablets. It depends on whether your doctor has prescribed the tablets for the treatment or prevention of a herpes infection, whether your immune system is intact or not and the type of disease. Herpes Simplex • Take for at least 5 days • One 200mg tablet five times each day • Take every four hours while awake (for example, 6am, 10am, 2pm, 6pm and 10pm). Shingles and chicken pox • Take for 7 days • Four 200mg tablets (800mg) five times each day • Take every four hours while awake (for example, 6am, 10am, 2pm, 6pm and 10pm). Black Children Herpes simplex • Take for at least 5 days. Children over 2 years • One 200mg tablet five times each day • Take every four hours while awake (for example, 6am, 10am, 2pm, 6pm and 10pm). Children under 2 years • One half of a 200mg tablet five times each day • Take every four hours while awake. Shingles This medicine should not be used to treat shingles in children. Chicken Pox • Take for 5 days. Age 6 years and above • Four 200mg tablets, four times each day. Age 2 to 5 years • Two 200mg tablets, four times each day. Under 2 years • One tablet four times each day. Elderly and people with kidney problems Your doctor may decide to lower your dose if you are elderly or have kidney problems.

Stopping your medicine Even if you feel well and your symptoms and lesions have gone, you should continue taking your tablets for as long as your doctor has told you. This is usually between 5 and 7 days for the treatment of acute infections and up to months for the prevention of recurrences. If you take more aciclovir than you should Talk to your doctor or go to your nearest hospital straight away. If you forget to take Aciclovir 200mg, 400mg, 800mg Tablets Do not take a double dose (two doses at the same time) to make up for a forgotten dose. Take your next dose as soon as you remember, then go on as before. However, if it is nearly time for the next dose, skip the missed dose. If you have any further questions on the use of this medicine, ask your doctor or pharmacist. 4. POSSIBLE SIDE EFFECTS Like all medicines, Aciclovir Tablets can cause side effects although not everybody gets them. If you have an allergic reaction to aciclovir see a doctor straight away. An allergic reaction may include: • Any kind of skin rash, flaking skin, boils or sore lips and mouth • Swelling of the face, lips, tongue or throat and difficulty breathing or swallowing • Sudden wheezing, fluttering or tightness of the chest or collapse. Other side effects include: Common (affects less than 1 in 10 people): • Headache, dizziness • Feeling sick, vomiting, diarrhoea, abdominal pains • Rashes (including rash caused due to sensitivity to sunlight) • Fever • Tiredness • Itching. Uncommon (affects less than 1 in 100 people): • Hair loss. Rare (affects less than 1 in 1,000 people): • Hypersensitivity reactions • Difficulty in breathing • Abnormal liver function tests • Abnormal kidney function tests • Skin rash causing red patches and itching • Swelling of the tissues. Very rare (affects less than 1 in 10,000 people): • Changes to the blood cells causing anaemia (pale skin), reduced immunity to infections, clotting disorders which may make you bruise easily • Agitation, confusion, tremor • Convulsions • Coma • Seeing or hearing things that are not present • Yellow discoloration of the skin & eyes • Enlarged liver • Kidney failure • Radiating pain in the back due to kidney problems • Lack of coordination of muscle movements • Sleepiness, speech disorder • Swelling of the brain (brain disorder).

If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. 5. HOW TO STORE ACICLOVIR TABLETS • Keep out of the reach and sight of children • Do not store above 25°C • Do not use after the expiry date (month, year) stated on the label and carton • If the medicine is out of date or you no longer need it, take the remaining tablets back to the pharmacy • Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicine no longer required. These measures will help protect the environment. 6. FURTHER INFORMATION What Aciclovir Tablets contain: • The active ingredient is aciclovir • The other ingredients are cellulose microcrystalline, sodium starch glycolate, polyvidone K25, magnesium stearate, colloidal anhydrous silica, purified water. What Aciclovir Tablets look like and contents of the pack: Aciclovir 200mg Tablets are white, odourless, round, unscored tablets. Aciclovir 200mg Tablets aluminium/PVC strip blister pack contains 25 or 60 tablets. Aciclovir 400mg Tablets are white, odourless, oblong, unscored tablets. Aciclovir 400mg Tablets aluminium/PVC strip blister pack contains 25, 56 or 60 tablets. Aciclovir 800mg Tablets are white, odourless, oblong, scored tablets. Aciclovir 800mg Tablets aluminium/PVC strip blister pack contains 35 tablets. Marketing Authorisation Holder and Manufacturer: Mercury Pharmaceuticals Ltd No. 1 Croydon, 12-16 Addiscombe Road, Croydon CR0 0XT, UK This leaflet was last revised in March 2012.

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Zotrim Review - Does It Work, Zytrim

Zotrim Review

Zotrim® – Helping you to Manage your Weight and Feel Full of Life Managing your weight in a way that helps you look good and stay healthy can be one of the hardest things to do in our modern lives.

The truth is that over 50% of the population are now overweight, which is why so many of us are looking for ways to maintain a healthy weight. There is now such a huge variety when it comes to great tasting foods and drink, it can often seem impossible not to over-indulge on high-calorie items. In the past we would have burned off these calories, but our modern lives are now far more sedentary – making it harder and harder to burn off these calories and keep out bodies in good condition.

Zotrim has been specially designed as a way to help with both of these issues:

Consume less calories: The formulation of Zotrim is designed to make you feel full during a meal, and for longer after the meal, to help you snack a lot less.

Burn off more calories: Zotrim can also help you to feel more energetic, which will in turn help you to burn of the calories that you do consume a lot quicker. Zotrim has been tested in a number of clinical trials and has shown excellent weight loss results.

You do not need to alter your lifestyle to see these changes, though with some changes in your diet and exercise regimen Zotrim will work even more effectively.

If you want to use Zotrim to help you make changes in the way you look, feel and eat then you can sign up to the Zotrim Step-by-Step Challenge. This challenge is there to guide you through the whole process of reaching your goals, sending you one email a week for 10 weeks full of different ways to lose weight healthily and consistently, and ultimately keep your weight under control.

Zotrim’s Natural Ingredients

All of the active weight loss ingredients found in Zotrim are special extracts from South American Plants, all of which have been traditionally used for their invigorating and stimulating properties.

Zotrim’s formulated has resulted from years of research performed by an international team of experts, led by the weight loss expert Dr Lasse Hessel. This research included studies taken by Cornell University of New York, the Middlesex Hospital in London and several clinics in France and Denmark.

These plants used in the formulation for Zotrim have also been used for centuries in South America, as part of traditional food and drink, due to their beneficial effects including invigorators and stimulants. The three plants contained in Zotrim are:

Yerbe Mate (Ilex paraguariensis)

This is a small tree that grows throughout semi-tropical regions of South America and is part of the holly family.

It is now widely cultivated due to such high demand – in Argentina and Uruguay its leaves are used for hot drinks, making both tea and coffee.

This use is now becoming more popular around the world due to its invigorating and stimulating effects.

Guarana (Paullinia cupana)

This is a climbing shrub, growing up to 12m high. This plant is native to the Amazon and cultivated in Brazil. Its seeds contain 2-3 times more caffeine than coffee beans, and are ground to a paste that is popular in drinks. This has, in fact, become the ‘national drink’ of Brazil after years of use by the native Amazonian tribes.

Guarana is mostly known for its stimulating effects and general health benefits – there is growing evidence that it can even improve mental and cognitive performance.

Damiana (Turnera aphrodisiaca)

This small shrub is found throughout the Caribbean, Mexico and Central America. Its leaves have always been used traditionally to make tea, and they are collected during flowering. This drink is reputed to have aphrodisiac qualities and has been used for this purpose since the Mayans.

In history, Spanish missionaries reported back that Mexican Indians drank this tea as a way to enhance lovemaking, though it is now also promoted as a method of invigoration.

Zotrim’s Effectiveness

Zotrim is a completely unique, patented herbal supplement that has proven evidence for its effects on weight loss. This evidence is what sets it apart from all the other non-medicinal weight loss products – it has been confirmed as the only supplement with real scientific proof.

Studies of Zotrim

1) Placebo Controlled Study of Weight Loss

Studies of Zotrim has been done for 45 days to understand the effects it has on weight loss. 47 overweight subjects ages 20-60 were allocated either a placebo or the Zotrim formulation – instructed to take three tablets with water before their main meals.

The study showed that those taking Zotrim lost an average of 5.1 kilograms (or 11.3 pounds) compared to just 0.3 kilograms (0.7 pounds) lost when taking the placebo.

2) Weight Maintenance

One of the hardest things about losing weight is keeping the weight off. This is why a follow up study was undertaken in order to show how successful Zotrim is in maintaining weight loss. Twenty-two out of the twenty-four who had been taking weight loss were allowed to keep taking it for another twelve months, weighed monthly. The result was that their ideal weight was maintained – where the average weight started at 73 kilograms (161 pounds) and ended at 72.5 kilograms (160 pounds) after the 12 months.

3) Weight Loss and Eating Behavior

A test was performed with 50 UK consumers looking to lose weight. They were given Zotrim and instructed to take two tablets, three times a day, with a glass of water before meals. The average weight loss over 28 days was shown to be 2.5 kilograms (5.5 pounds), over half said they were eating less than usual, and two thirds said that they were now snacking less in between meals.

4) Gastric Emptying Study

Stomach fullness and the gastric emptying rate are known to be closely connected to the mechanisms of eating control, so a study was undertaken to test Zotrim’s effect in this area. Seven previously fasted subjects were tested and they took three capsules of Zotrim or three placebo capsules with 20ml of apple juice, followed by 400 ml of apple juice 15 minutes later.

Gastric volume was then measured every 10 minutes and the time it took to empty the stomach. The test showed that the average time it took to empty the stomach was 58 minutes for those taking Zotrim, and 38 minutes when taking the placebo.

The time it took to a perceived fullness was investigated in 20 subjects, who took two capsules of Zotrim or two placebo capsules before meals. They recorded the time that it took for them to feel full during each meal. On average, the combined time to feel full over three meals was 35 minutes with Zotrim, and 61 minutes with the placebo.

6) Effect on Snacking and TV Viewing

TV viewing has been shown as a factor in influencing eating behavior and becoming overweight. This is why the effect of TV viewing and Zotrim on energy intake from snacks was studied in 11 adults. Those tested either took two Zotrim tablets or two placebo tablets with a drink in the morning and before lunch. Two hours after lunch, those tested would be given access to a TV video or a blank screen with access to unlimited snacks, and their total energy intake was measured. The energy intake was a lot higher when subjects were watching the TV compared to when not watching. And their energy intake whilst watching TV was also reduced when the subjects took Zotrim.

7) Effect of Zotrim on Waist Circumference

In one test, 61 overweight women took Zotrim for four weeks. Their eating patterns and hunger were all recorded through questionnaires, and weight loss and waist measurements were taken at intervals of two weeks. The average weight loss was 1.8kg (4lbs) in the four weeks, with an average waist reduction of around 4.3cm (just under 2 inches) in the four weeks. Those tested felt less hungry in between meals and fuller after meals.

8) Study With Healthcare Professionals

The most recent Zotrim study involved 70 healthcare professionals who took the formula for six weeks. The results of the study showed that 2.3 kg was the average six-week weight loss. The average reduction in waist circumference was 3.4cm. Hunger between meals was reduced, consumption of snacks was less, and those tested felt fuller after meals. 22% of those involved in this test lost more than 5% of their original weight. This weight loss can have a significant impact on health, especially when weight is lost from the abdominal areas.

Zotrim Precautions and Side Effects

1) Who Shouldn’t Take Zotrim?

You shouldn’t take Zotrim if you’re under 16, if you are pregnant or breastfeeding, or if you are sensitive to caffeine. To our knowledge Zotrim should not interact badly with any other medicine. However, if you are on medication or are worried about taking Zotrim then you should consult your doctor. If, when taking Zotrim, you feel ill for any reason then we recommend that you stop taking it until you feel better.

2) Are There Side Effects When Taking Zotrim?

Zotrim is a food supplement made from plant extracts, and as such has a good record when it comes to safety. There have been no side effects reported in the main trials undertaken using the formulation. However, some people have occasionally complained of feeling nauseous when they first start taking Zotrim. If you have any health problems you should always consult your doctor before taking Zotrim.

One of the main ingredients of Zotrim – Guarana – contains natural caffeine. This is why Zotrim should be avoided by anyone sensitive to caffeine. When taking Zotrim in a day, you will find the amount of caffeine equivalent to one cup of coffee. When you are taking Zotrim, should you feel ill or suffer from any adverse effects, you should stop taking the tablets, and consult a doctor if the symptoms persist or are serious.

3) How Much Caffeine Does Zotrim Contain?

The caffeine in one day’s worth of Zotrim is equivalent to about one cup of coffee. If you are adversely affected by caffeine then you should not take Zotrim.

4) Will Zotrim Interact With Other Medicine?

There is no evidence that Zotrim interacts with any other medicine.

5) Should Diabetics Use Zotrim?

There has been no evidence to suggest that Zotrim should not be used by diabetics. However, it is advisable to consult your doctor before taking Zotrim.

6) Can Zotrim Be Taken At The Same Time As Thyroxin?

There is no reason that you should not take Zotrim at the same time as Thyroxin. However, it is advisable for all new customers who are already on any kind of medication to consult their doctor before they start taking Zotrim.

7) Does Zotrim Interfere With the Oral Contraceptive?

This is a food supplement, and not a medicine, so Zotrim will not affect your oral contraceptive.

8) Can Zotrim Be Taken Whilst Pregnant or Breastfeeding?

We advise that you do not take Zotrim during pregnancy or breastfeeding. However, Zotrim can be used to get back into shape and get your diet under control after birth and breastfeeding.

9) What If My Doctor Doesn’t Know Anything About Zotrim?

It is best to take along the pack of Zotrim, along with its insert, to show to your doctor. This includes all of the essential information that they need to know. You can also refer to the website for more detailed information or you can contact us directly.

Dr. Walt Mellgren Jr. on Lotto Crusher Review

Posted on: 28-04-2015

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