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Proper name: pentoxifylline Chemical name: 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine -2,6-dione Molecular formula: C 13 H 18 N 4 O 3 Molecular mass: 278.3 Structural formula:

Pentoxifylline is a white to creamy white, crystalline powder. It is freely soluble in chloroform and methanol, soluble in water, sparingly soluble in ethanol and slightly soluble in ether. It has a melting point of 104°C to 107°C, within a 3°C range.

What are the possible side effects of pentoxifylline (Trental)?

Stop taking this medication and get emergency medical help if you have any of these signs of an allergic reaction . hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

chest pain,

pounding heartbeats or fluttering in your chest;

feeling like you might pass out;

red or pink urine;

bloody, black, or tarry stools; or

coughing up blood or vomit that looks like coffee grounds.

Less serious side effects may.

What are the precautions when taking pentoxifylline (Trental)?

Before taking pentoxifylline, tell your doctor or pharmacist if you are allergic to it; or to caffeine, or theophylline; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: recent stroke, recent bleeding in the eye, kidney problems, liver problems, recent major surgery, stomach ulcer.

This drug may rarely make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the.

Last reviewed on RxList: 7/16/2012 This monograph has been modified to include the generic and brand name in many instances.