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Rendapid [in more detail]

For the treatment of hypercholesterolemia.

Rendapid Mechanism Of Action:

The 6-membered lactone ring of simvastatin is hydrolyzed in vivo to generate mevinolinic acid, an active metabolite structurally similar to HMG-CoA (hydroxymethylglutaryl CoA). Once hydrolyzed, simvastatin competes with HMG-CoA for HMG-CoA reductase, a hepatic microsomal enzyme. Interference with the activity of this enzyme reduces the quantity of mevalonic acid, a precursor of cholesterol.

Rendapid Drug Interactions:

Food Interactions:

Avoid drastic changes in dietary habit. Avoid alcohol. Avoid taking with grapefruit juice.

Rendapid Chemical Formula:

Input interpretation

Chemical names and formulas

Structure diagram

3D structure

Basic properties

Hydrophobicity and permeability properties

Basic drug properties