Vivacor 5mg Tablets, Vivacor

VIVACOR 5MG TABLETS

Transcript

Very rare (affects less than 1 person in 10,000): • irritation and redness of the eye (conjunctivitis) • hair loss • appearance or worsening of scaly skin rash (psoriasis); psoriasislike rash. Tell your doctor or your pharmacist if you notice any of the side effects listed above or any other unwanted or unexpected effects. How to look after your medicine? Bisoprolol Tablets also contain: maize starch, microcrystalline cellulose, crospovidone, calcium hydrogen phosphate, magnesium stearate and silica. The film coat contains: hypromellose, titanium dioxide (E171), macrogol, dimethicone and iron oxide (E172). Bisoprolol Tablets are marketed in pack sizes of 28. Bisoprolol Fumarate is a beta-blocker medicine. Beta-blockers reduce the force and speed of your heart beat. The 5 mg tablets are round, ivory coloured biconvex tablets and are marked with a score line on one face. The 10 mg tablets are round, light brown coloured biconvex tablets and are also marked with a score line on one face. Do not use the tablets after the expiry date (use by) date shown on the product packaging. Do not store the tablets above 30°C and keep them in the original packaging. Keep your tablets out of sight and reach of children. Return any unused medicine to the pharmacist. Bisoprolol Tablets 5 mg: PL No. 42311/0001 Bisoprolol Tablets 10 mg: PL No. 42311/0002 Date of last text revision: 06/2013

Bisoprolol 5 mg and 10 mg Tablets Patients Information Leaflet This leaflet gives you some important information about your medicine. Please read it carefully before you start taking your medicine. About your medicine Bisoprolol Tablets are coated tablets containing either 5 mg or 10 mg of the active ingredient Bisoprolol fumarate. What is your medicine used for? Bisoprolol Tablets are used: • to reduce high blood pressure (hypertension). • to relieve chest pain (angina) Before you take Bisoprolol Tablets Do not use Bisoprolol tablets if you: • have you ever had an allergic (hypersensitive) reaction to bisoprolol fumarate or any of the ingredients in the tablet with symptoms of a rash, itching or difficulty breathing. • have suffered from sudden heart failure, irregular heart beats or a slow heart rate • suffer from extremely low blood pressure • suffer from lung disease, asthma, have a family history of asthma. • suffer from diseases which affect blood flow to your fingers and toes e. g Raynaud’s syndrome • have untreated adrenal gland tumour called phaeochromocytoma • have metabolic acidosis which would be measured by a blood test by your doctor Take special care with Bisoprolol tablets Tell your doctor or pharmacist before you start using these tablets if you:

For any information about this medicinal product, please contact : MA Holder:

Pharmacare (London) Ltd., The Office, Heath View, Blindley Heath, Lingfield, RH7 6LH, UK.

• suffer from any heart disease, including heart failure and angina • suffer from bronchospasm associated with bronchial asthma and other lung diseases • suffer from severe kidney or liver disease • suffer from uncontrolled diabetes • are fasting • • • •

having desensitisation treatment for allergies suffer from psoriasis or have a history of psoriasis have thyroid problems are due to go into hospital for an operation then tell your doctor.

Treatment with Bisoprolol should not be stopped suddenly especially in patients already with heart disease. 4

Taking other medicines Please tell your doctor or pharmacist if you are taking any of the following medicines • diltiazem, verapamil or other calcium blockers used to treat heart problems • clonidine, methyldopa, moxonidine or rilmenidine used to treat high blood pressure • nifedipine, isoprenaline or dobutamine used to treat heart conditions • amiodarone, dis oyramide, quinidine, mefloquine or digoxin used to treat problems with heart rhythms • eye drops used to treat glaucoma • insulin, glibenclamide or metformin used to treat diabetes • some anaesthetics • Non steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen used to treat pain • adrenaline used to treat allergic reactions • antidepressants such as amitriptyline, imipramine, barbiturates, chlorpromazine, levomepromazine and Monoamine-oxidase inhibitors (MAOIs) such as phenelzine • moxisylate used to treat circulation problems such as Raynaud’s syndrome Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Pregnancy and breastfeeding Do not take this medicine if you are pregnant or breast-feeding. If you are taking it and think that you may be pregnant or are planning a family, consult your doctor. Driving and using machines: It is possible that you may react to Bisoprolol. Reactions may vary from person to person and may impair your ability to drive or operate machinery. This applies particularly at the start of treatment, on changing the medication and in combination with alcohol. How to take your medicine You should follow your doctor's instructions. You can check the pharmacy label to see how many tablets the doctor has recommended you take and how often you should take them. The usual dosage(s) are: Indication Dosage Adults & Elderly: The usual dose is 10 mg once daily. The maximum dose is 20 mg per day. Some patients may only require 5 mg per day. If you are elderly or have severe liver or kidney damage you may be given a smaller dose. Children: Bisoprolol Tablets are not recommended for children. 2

Swallow these tablets with water. This medicine should be taken for as long as your doctor tells you to. It may be dangerous to stop without their advice. Follow your doctor's advice on how to stop taking this medicine. You should not stop taking them abruptly. If you forget to take a dose, take one as soon as you remember. DO NOT take two doses at the same time. If you are worried, ask your pharmacist or doctor for advice. Do not take more tablets than your doctor tells you to. If you ever take too many, go to the nearest hospital casualty department or tell your doctor immediately. Take the container, any remaining tablets and this leaflet with you to show to the doctor. What side effects may occur? This medicine sometimes causes unwanted effects in some people. The most serious side effects are related to the heart function: • slowing of heart rate (affects more than 1 person in 10) • worsening of heart failure (affects less than 1 person in 10) • slow or irregular heartbeat (affects less than 1 person in 100) Inflammation of the liver which can cause the yellowing of the skin or whites of the eyes. If you feel dizzy or weak, or have breathing difficulties please contact your doctor as soon as possible. Further side effects are listed below according to how frequently they may occur: Common (affects less than 1 person in 10): • tiredness, feeling weak, dizziness, headache • feeling of coldness or numbness in hands or feet • low blood pressure • stomach or intestine problems such as nausea, vomiting, diarrhoea, or constipation. Uncommon (affects less than 1 person in 100): • sleep disturbances • depression • dizziness when standing up • breathing problems in patients with asthma or chronic lung disease • muscle weakness, muscle cramps. Rare (affects less than 1 person in 1,000): • hearing problems • allergic runny nose • reduced tear flow • certain blood test results for liver function or fat levels differing from normal • allergy-like reactions such as itching, flush, rash • impaired erection • nightmares, hallucinations • fainting 3

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Resin Coating - Diary Cold Storage Floors And Walls, Norphen

Search steps:

The ideal floor is formed by NORPHEN 200 HCR, a base of epoxy resin applied using the multilayer method, broadcast with quartz sand 0.3-0.9.

Applying the coating

On a concrete surface proceed to skim coat using NORPHEN FONDO SL charged and broadcast to excess with quartz sand 0.3 to 0.9.

Once the product has hardened, finish the surface with a coat of NORPHEN 200 HCR lying it down with a steel spatula.

The ideal coating is made of an epoxy resin specifically designed for the food industry: NORPHEN FOOD

Applying the coating

On a surface previously prepared with cement sand plaster apply one or two coats of NORPHEN FOOD.

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Dropstar Wheels, Dropstar

About Dropstar

Dropstar Wheels and Rims

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X Tran Mf; Tablet, Intra Labs, Tran-Mf

X Tran MF - Tablet, Intra Labs.

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Stelax Tablets, Stelax

STELAX

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about STELAX.

It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have benefits and risks. Your doctor has weighed the risks of you taking STELAX against the benefits they expect it will have for you.

Talk to your doctor or pharmacist if you have any concerns about taking this medicine. Keep this leaflet with your medicine. You may need to read it again.

What STELAX is used for

STELAX is used to treat muscle spasms that occur in various illnesses such as multiple sclerosis and diseases and injuries of the spinal cord.

STELAX belongs to a group of medicines called muscle relaxants. These medicines reduce excess tension in your muscles that cause spasms and pain. Reducing these spasms may help to increase your mobility and make everyday activities easier to manage.

Your doctor may have prescribed this medicine for another reason. Ask your doctor if you have any questions about why it has been prescribed for you.

It is available only with a doctor's prescription.

Before you take it

When you must not take it

Do not take STELAX if you are allergic to medicines containing baclofen or any of the ingredients listed at the end of this leaflet.

Do not take it if the expiry date (Exp.) printed on the pack has passed.

Do not take it if the packaging shows signs of tampering or the tablets do not look quite right.

Before you start to take it

Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.

Tell your doctor if you are pregnant or plan to become pregnant. Your doctor will discuss the risks and benefits of taking STELAX during pregnancy.

Tell your doctor if you are breastfeeding or wish to breastfeed. Your doctor will discuss the risks and benefits of taking STELAX when breastfeeding.

Tell your doctor if you have, or have had, any medical conditions, especially the following:

a mental illness

epilepsy or fits

stomach ulcers

stroke or other blood vessel disease

heart disease

liver disease

kidney disease

lung or breathing problems

diabetes

alcoholism

high blood pressure

porphyria, a rare blood disorder.

If you have not told your doctor about any of the above, tell them before you start taking STELAX.

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may be affected by STELAX, or may affect how well it works. These include:

medicines used to treat diabetes

medicines used to treat high blood pressure

medicines used to treat depression such as tricyclic antidepressants and monoamine oxidase inhibitors

lithium, a medicine used to treat mental illness

levodopa and carbidopa, medicines used to treat Parkinson’s disease

any medicine that can make you sleepy, such as medicines to help you sleep or calm you down, pain relievers and medicines for colds and allergies.

Your doctor can tell you what to do if you are taking any of these medicines.

If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.

How to take it

How much to take

Treatment with STELAX is usually started in hospital with a small dose which is gradually increased to a dose that has the best result for you.

Your doctor will tell you how many tablets you need to take each day and when to take them.

Follow all directions given to you by your doctor and pharmacist carefully.

How to take it

Take your medicine during or immediately after food with a little glass of water. This will lessen the chance of a stomach upset.

If you forget to take it

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take the missed dose as soon as you remember, and then go back to taking your tablets as you would normally.

Do not take a double dose to make up for the dose you missed.

If you are not sure what to do, ask your doctor or pharmacist.

How long to take it for

To properly control your condition, STELAX must be taken every day.

Keep taking your medicine for as long as your doctor recommends.

If you take too much (overdose)

Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much STELAX. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

If you take too much, you may feel dizzy, weak or confused, have blurred vision, vomiting, diarrhoea, breathing problems, faint or have fits.

While you are taking it

Things you must do

Before starting any new medicine, tell your doctor or pharmacist that you are taking STELAX.

Tell all the doctors, dentists and pharmacists who are treating you that you are taking this medicine.

If you become pregnant while taking it, tell your doctor.

Visit your doctor regularly so they can check on your progress. To help prevent unwanted side effects from happening, your doctor may want to do some tests from time to time during the course of your treatment.

Things you must not do

Do not stop taking it suddenly, or lower the dose, without checking with your doctor. Stopping STELAX suddenly may cause severe spasms and other unwanted symptoms. Your doctor may want you to gradually reduce the amount of medicine you are taking before stopping completely.

Do not use STELAX to treat any other conditions unless your doctor tells you to.

Do not give it to anyone else, even if they have the same condition as you.

Things to be careful of

Be careful driving or operating machinery until you know how STELAX affects you. It may cause drowsiness or decrease alertness in some people. If either of these occur, do not drive, operate machinery or do anything else that could be dangerous.

Be careful when drinking alcohol while taking this medicine. Combining it with alcohol can make you more drowsy and less alert.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking STELAX. Like all other medicines, it may have unwanted side effects in some people. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

If you are over 65 years of age, you may have an increased chance of getting side effects.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if you notice any of the following and they worry you:

sleepiness or drowsiness

lack of energy, feeling exhausted

dizziness, lightheadedness

confusion

headache

difficulty sleeping, nightmares

feeling sick (nausea), vomiting

constipation, stomach pain, diarrhoea

change in taste

numbness or tingling in the hands or feet

muscle weakness, spasms or pain

problems with co-ordination or balance

blurred or double vision

ringing in the ears

frequent urination or bed wetting

excessive sweating

weight gain

impotence or inability to ejaculate

Tell your doctor immediately if you notice any of the following:

slow or difficult breathing

fast or irregular heartbeat

chest pain

uncontrolled muscle spasms affecting the eyes, head, neck or body

fainting or fits

depression or other severe mood changes or mental changes

hallucinations

inability to urinate, pain when urinating, blood in the urine.

Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything that is making you feel unwell.

After using it

Storage

Keep your medicine where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Keep your tablets in a cool dry place where the temperature stays below 25°C.

Do not store STELAX or any other medicine in the bathroom or near a sink.

Do not leave it in the car or on window sills. Heat and dampness can destroy some medicines.

Disposal

If your doctor tells you to stop taking STELAX, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Product description

What it looks like

STELAX comes in 2 strengths of tablets:

STELAX 10 - round off-white tablet marked BL|10 and >.

STELAX 25 - round off-white tablet marked BL|25 and >.

Each pack contains 100 tablets.

Ingredients

The active ingredient in STELAX is baclofen.

each STELAX 10 tablet contains 10 mg of baclofen

each STELAX 25 tablet contains 25 mg of baclofen.

The tablets also contain:

microcrystalline cellulose

maize starch

povidone

colloidal anhydrous silica

magnesium stearate.

The tablets are gluten free.

Manufacturer

Aspen Pharma Pty Ltd 34-36 Chandos Street St Leonards NSW 2065 Australia

Australian registration numbers: STELAX 10 - Aust R 92251 STELAX 25 - Aust R 92252

This leaflet was revised in May 2012

Published by MIMS April 2014

Consumers should be aware that the information provided by the Consumer Medicines Information (CMI) search (CMI Search) is for information purposes only and consumers should continue to obtain professional advice from a qualified healthcare professional regarding any condition for which they have searched for CMI. CMIs are provided by MIMS Australia. CMI is supplied by the relevant pharmaceutical company for each consumer medical product. All copyright and responsibility for CMI is that of the relevant pharmaceutical company. MIMS Australia uses its best endeavours to ensure that at the time of publishing, as indicated on the publishing date for each resource (e. g. Published by MIMS/myDr January 2007), the CMI provided was complete to the best of MIMS Australia's knowledge. The CMI and the CMI Search are not intended to be used by consumers to diagnose, treat, cure or prevent any disease or for any therapeutic purpose. Cirrus Media Pty Limited, its servants and agents shall not be responsible for the continued currency of the CMI, or for any errors, omissions or inaccuracies in the CMI and/or the CMI Search whether arising from negligence or otherwise or from any other consequence arising there from.

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Maxibral, Maxibral

TRAVAMAX Granules

COMPOSITION: Each 5 gm contains : Glycyrrhiza glabra 149.00 mg Adhatoda vasika 87.00 mg Foeniculum vulgare 123.00 mg Valeriana officinalis 78.00 mg Eucalyptus globulus 63.00 mg Honey 100.00 mg Citrus medica 0.20 ml Ginger 70.00 mg

DESCRIPTION : Travamax herbal granules is a delicate balance of pure and carefully selected herbs, which work as strong expectorant and decongestant. Travamax herbal granules instantly dissolve and have a delicious blend of honey & lemon taste. Travamax herbal granules provides relief in cough, cold, flu and other associated symptoms like sore throat and blocked nose.

CONTRA-INDICATIONS : Person with hypersensitivity to any of the contents of the products.

SIDE EFFECTS : The ingredients of Travamax herbal granules are usually well tolerated in normal use but in the condition of hyper sensitivity, allergic reaction, may occur occasionally. Symptoms of side effects (if any) should subside after discontinuing medicine.

PRECAUTIONS : There are no known problems during pregnancy & lactation but it should be used with the advice of a doctor during this period. Check the expiry on the pack and do not use after expiry date.

DIRECTION OF USE : Dissolve one sachet in a cup of hot water and drink slowly. One sachet at a time, 3-4 times a day or as and when required. Half sachet in ? cup of hot water 3-4 times a day or as and when required is recommended for children below 12 years of age. No need to filter it. Do not add sugar or milk.

Travamax herbal granules has a pleasant flavour of honey and lemon.

It doesn’t contain any synthetic substance or chemicals.

It is not a narcotic dependence medicine, so can be freely used by elderly and children.

Travamax herbal granules dissolve in hot water instantly and completely, so no need to filter it.

PRESENTATION : One box contains 5 sachets of Travamax herbal granules.

Dynacin, Dynacin

Dynacin

Dynacin is a tetracycline antibiotic used to treat a variety of infections, including acne, urinary tract infections (UTIs), and pneumonia. This medication comes in tablet form and is taken two to four times a day. Possible side effects include nausea, vomiting, and decreased appetite, among others. It's important to finish the full course of this antibiotic, even if you start to feel better.

What Is Dynacin?

Dynacin ® (minocycline hydrochloride) is a prescription antibiotic medication from the tetracycline class of antibiotics. It is approved to treat a variety of different infections, such as:

(Click Dynacin Uses for more information on this topic, including possible off-label uses.)

Who Makes Dynacin?

This medication is made by Par Pharmaceutical Companies, Inc. for Medicis Pharmaceutical Corporation.

How Does It Work?

Like other tetracycline antibiotics, Dynacin reduces the ability of bacteria to make proteins. Dynacin does not directly kill the bacteria; however, by inhibiting protein production, it reduces their ability to grow and multiply. This gives the immune system a chance to fight the bacteria.

The exact way Dynacin works to treat acne is unknown. The medication likely slows the growth of the bacteria that cause acne. It may also reduce inflammation, decreasing the amount of red, inflamed bumps and pimples.

Buy Kenacomb Online From Canada Drugs - Online Canadian Pharmacy, Kenacomb

Kenacomb and/or Equivalents

Viaderm-K. C. Viaderm-K. C. Cream

Best Price Guaranteed on Kenacomb Medication

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If you have any questions about buying discount Kenacomb online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784.

Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

About Canada Drugs Canada Drugs Blog Site Map

© 2016 CanadaDrugs. com

Toll-Free Phone: 1-800-226-3784 International Phone: 1-204-654-7964 Hearing Impaired TTY Service: 1-877-258-7006

For Media and/or Advertising Inquiries Please Contact: Brock Gunter-Smith, Chief Business Development Officer p. +1 (204) 654-7950 or e. brock@canadadrugs. com

Send prescriptions, order forms and documents to:

24 Terracon Place Winnipeg, MB R2J 4G7 Canada

Hours of Operation Call Centre (sales, refill and order information): 24 hours, 7 days a week Pharmacy: Monday to Friday 8:00 am to 4:00 pm CST Exceptions: Closed December 24th 6:00 pm to December 26th 7:00 am CST, Closed December 31st 6:00 pm to January 1st 7:00 am CST

To provide a secure and safe shopping experience, Canada Drugs is committed to meeting and exceeding all standards outlined by the leading pharmacy accreditation organizations.

Be advised that, given the international nature of the practice of International Prescription Services (IPS) pharmacy, there may be limitations in the ability of the College of Pharmacists of Manitoba (CPhM), which is the statutory licensing authority for pharmacies and pharmacists in the Province of Manitoba, to investigate and prosecute complaints from persons who receive services or products from an IPS pharmacy. Manitoba pharmacists are not permitted to fill US physicians' prescriptions. They can only fill prescriptions issued by a physician licensed in a province or territory of Canada. C. Ph. M. takes the position that it may be contrary to professional standards for a pharmacist to fill prescriptions by a physician, licensed in a province or territory of Canada, who has not established an acceptable patient physician relationship with you. CanadaDrugs. com is presently licensed in the province of Manitoba by the College of Pharmacists of Manitoba. License Number 32195

* All prices are subject to change at any time. Exchange rates under license from XE. com. For questions regarding pricing and availability of products from Canada Drugs you may call 1-800-226-3784.

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Hysetin, Hysetin

Chloramphenicol (Hysetin)

Chloramphenicol is used for treating serious infections caused by certain bacteria. Chloramphenicol is an antibiotic. It works by killing or slowing the growth of sensitive bacteria.

Use Chloramphenicol as directed by your doctor.

Take Chloramphenicol by mouth with or without food.

If you miss a dose of Chloramphenicol, use it as soon as possible. Then use your doses at evenly spaced times as directed by your doctor. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Chloramphenicol.

Store Chloramphenicol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Chloramphenicol out of the reach of children and away from pets.

Do NOT use Chloramphenicol if:

you are allergic to any ingredient in Chloramphenicol

you have previously had serious side effects from Chloramphenicol

you have a low white or red blood cell count or decreased blood platelets

you have a minor infection such as a cold, flu, throat infection, or you are using Chloramphenicol to prevent a bacterial infection

you are taking other medicines that may decrease your bone marrow (eg, cancer chemotherapy); check with your doctor or pharmacist if you are unsure if any of your other medicines may decrease your bone marrow.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Chloramphenicol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have anemia, bone marrow problems, liver disease, or kidney problems.

Some medicines may interact with Chloramphenicol. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because side effects, including risk of bleeding, may be increased

Hydantoins (eg, phenytoin) or sulfonylureas (eg, glyburide) because the actions and side effects of these medicines may be increased.

Medicines that may decrease your bone marrow (eg, cancer chemotherapy ) because the risk of serious side effects, such as low blood platelet levels and low white blood cell counts, may be increased; check with your doctor or pharmacist if you are unsure if any of your medicines may decrease your bone marrow.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chloramphenicol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Do not exceed the recommended dose or use Chloramphenicol for longer than prescribed without checking with your doctor.

Chloramphenicol is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).

It is important to use Chloramphenicol for the full course of treatment. Failure to do so may decrease the effectiveness of Chloramphenicol and increase the risk that the bacteria will no longer be sensitive to Chloramphenicol and will not be able to be treated by this or certain other antibiotics in the future.

Long-term or repeated use of Chloramphenicol may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.

If symptoms of "gray syndrome" (swelling of the abdomen, pale or blue skin color, vomiting, shock, difficulty breathing, refusal to suck, loose green stools, limp muscles, low temperature) occur in a newborn or infant, contact your doctor. Death may occur within hours of the onset of symptoms. Stopping use of Chloramphenicol when symptoms first appear increases the chance for a complete recovery.

Chloramphenicol may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.

Chloramphenicol may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.

Diabetes patients - Chloramphenicol may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.

LAB TESTS, including complete blood cell counts, may be performed to monitor your progress or check for side effects. Be sure to keep all doctor and lab appointments.

Use Chloramphenicol with extreme caution in children younger 1 year. Safety and effectiveness in this age group have not been confirmed.

Use Chloramphenicol with extreme caution in children younger 10 years who have diarrhea or a stomach or bowel infection.

Use Chloramphenicol with extreme caution in premature and full-term infants because they may be more sensitive to the effects of Chloramphenicol, especially the risk of "gray syndrome."

Pregnancy and breast-feeding: If you become pregnant while taking Chloramphenicol, discuss with your doctor the benefits and risks of using Chloramphenicol during pregnancy. Chloramphenicol should be used with extreme caution during full-term pregnancy and labor because the fetus may experience severe side effects. Chloramphenicol is excreted in breast milk. Do not breastfeed while taking Chloramphenicol.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Mild diarrhea, nausea, or vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; dark urine; delirium; depression; headache; fever, chills, or sore throat; pain, redness, or swelling at the injection site; symptoms of "gray syndrome" in an infant (swelling of the abdomen, pale or blue skin color, vomiting, shock, difficulty breathing, refusal to suck, loose green stools, limp muscles, low temperature); unusual bleeding or bruising; unusual tiredness; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Duomycin

In some countries, this medicine may only be approved for veterinary use.

Found in: Switzerland

Duomycin is NOT known to be marketed in the USA. Duomycin may be available in the countries listed above.

Generic/rINN (Recommended International Nonproprietary Name)

ATC (Anatomical Therapeutic Chemical Classification)

CAS registry number (Chemical Abstracts Service)

Chemical Name

Other Brand Names

Amacin

Anasilpiel

Antibioptal

Apolar-N

Atebemyxine

Bac Neo Poly

Bacimycin

Bacitracin-Neomycin-Polymyxin

Baneocin

Baramycin

Berbesolone F

Berloson-N

Bestflan

Betason-N

Betaval-N

Betnesol-N

Betnevate N

Betnovate-N

Bevalex

Bevason

Bimixin

Bio Delta Cortilen

Bioderm

Bioplacenton

Biosol

Bivacyn

Bravoderm-N

Calf meal

Cebemyxine

Celestonvalerat

Chlomy-P

Cicatrin

Cilinafosal Neomicina

Cinolon-N

Cloxagel

CNF Scour-diet

Colimy Foam

Coliriocilina Prednisona

Colivet

Compomix

Concatag

Concentrat

Cortexiline

Cortidexason comp.

Cortikan

Cortizeme

Cysto-Myacyne

Denomix

Dentargle F

Dermamycin

Dermoran F

Desalfa

Desamix Neomicina

Desolex-N

Dexagrane

Dexapolcort N

Dexavetaderm

Diarcap

Dispadex comp.

Doricum

Ecoval

Emorex N Berna

Endomycin

Enteran

Enterocoli

Enteromicina

Enterostop

Entocunimycine

Escar-T

Eta Biocortilen

Fasolon

Fast Powder

Flucort F

Fludroxyl

Fluocort-N

FML-Neo

Forticillin

Fradiomycin

Fradiomycin Celludent

Framykoin

Francetin T

Furafenicol Vet

Halciderm Combi

Hydeltrone

Hydrocortiderm

Hydrocortisel

Hysetin P

Hyspan

Izoneocol

Jenomycin

Kalcinol-N

Kataval

Kenacort A con Neomicina

Kenacort AG

Leuco Hubber

Lincocin forte

Lincocin Neo

Lincocine

Locacorten

Mammaneopen

Mastalone

Mastalone Blue

Mastijet

Mastitar

Mastrinal

Maxitrol

Menaderm

Menaderm Neomicina

Metaskin-N

Myacyne

Myciguent

Mycitracin

Myneocin

Myrosone

Mytaderm

N B Topical

Naseptin

Nebacetin

Neo

Neo Cortef

Neo Delta Cortef

Neo Franvet

Neo Hubber

Neo Mastitar

Neo Medrol EE

Neo Predef

Neo Sol

Neo synalar

Neo Terramycin

Neo-Bacin

Neo-Flucort

Neo-Fradin

Neo-Hydro

Neo-M-Salbe

Neo-Rx

Neo-Sulcin

Neobacin

Neobacitracine

Neobiotic

Neocin

Neocina

Neoclox

Neocones

Neocortic

Neoderm

Neodex

Neoject

Neomas

Neomed

Neomicina

Neomicina L. CH.

Neomix

Neomy

Neomycane

Neomycin and Polymyxin B Sulfate

Neomycin Penicillin

Neomycin Sulfate

Neomycin-Penicillin

Neomycine Avitec

Neomycine Diamant

Neomycine Franvet

Neomycine Hydrocortisone

Neomycinesulfaat

Neomycinesulfaat CF

Neomycinsulfat

Neomycinum

Neomydiar

Neopen

Neopenol

Neopharm

Neoral

Neosel

Neosinol

Neosol

Neosporin

Neosporin Irrigating Solution

Neosulf

Neotracin

Neoxyne

Nisagon

Nivemycin

NP8

NPA Euterschutz

NPS Vetag

Nufacort

Ocemycine

Oftalmolosa Cusi Prednisona Neomicina

Ophtalkan

Ophthalmo-Framykoin

Ophthalmyvet

Optiprime

Optisone

Oregan

Orojet

Pamycon

Panolog

Parkesteron

Pimafucort

Pivalone compositum

Polyspectran Salbe

Polyspectran Tropfen

Predniderm

Predsol-N

Prevotec

Pulvo 47

Rilexine

Salmocoli

Skizon-N

Special Formula 17900 Forte V

Speciorlac

Spersapolymyxin

Statrol

Sulfintestin Neomicina

Super-Mastitar

Synalar-N

Tabernil Cria

Tarivet

Tevemyxine

Tisuderma

Topocin

Tracetin

Traital

Trefurcan

Tricin

Triple Antibiotic Ointment

Tyrothricin Provita comp.

Unguentum Neomycini

Uro-Nebacetin

Vagicillin

Vetropolycin

Vonapen

Vonapen Retard

Antibiotics - Hysetin p (Brand name: chloramphenicol)

Chloramphenicol is used for treating serious infections caused by certain bacteria. Chloramphenicol is an antibiotic. It works by killing or slowing the growth of sensitive bacteria.

Use Chloramphenicol as directed by your doctor.

Take Chloramphenicol by mouth with or without food.

If you miss a dose of Chloramphenicol, use it as soon as possible. Then use your doses at evenly spaced times as directed by your doctor. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Chloramphenicol.

Store Chloramphenicol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Chloramphenicol out of the reach of children and away from pets.

Do NOT use Chloramphenicol if:

you are allergic to any ingredient in Chloramphenicol

you have previously had serious side effects from Chloramphenicol

you have a low white or red blood cell count or decreased blood platelets

you have a minor infection such as a cold, flu, throat infection, or you are using Chloramphenicol to prevent a bacterial infection

you are taking other medicines that may decrease your bone marrow (eg, cancer chemotherapy); check with your doctor or pharmacist if you are unsure if any of your other medicines may decrease your bone marrow.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Chloramphenicol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have anemia, bone marrow problems, liver disease, or kidney problems.

Some medicines may interact with Chloramphenicol. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because side effects, including risk of bleeding, may be increased

Hydantoins (eg, phenytoin) or sulfonylureas (eg, glyburide) because the actions and side effects of these medicines may be increased.

Medicines that may decrease your bone marrow (eg, cancer chemotherapy ) because the risk of serious side effects, such as low blood platelet levels and low white blood cell counts, may be increased; check with your doctor or pharmacist if you are unsure if any of your medicines may decrease your bone marrow.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Chloramphenicol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Do not exceed the recommended dose or use Chloramphenicol for longer than prescribed without checking with your doctor.

Chloramphenicol is effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).

It is important to use Chloramphenicol for the full course of treatment. Failure to do so may decrease the effectiveness of Chloramphenicol and increase the risk that the bacteria will no longer be sensitive to Chloramphenicol and will not be able to be treated by this or certain other antibiotics in the future.

Long-term or repeated use of Chloramphenicol may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.

If symptoms of "gray syndrome" (swelling of the abdomen, pale or blue skin color, vomiting, shock, difficulty breathing, refusal to suck, loose green stools, limp muscles, low temperature) occur in a newborn or infant, contact your doctor. Death may occur within hours of the onset of symptoms. Stopping use of Chloramphenicol when symptoms first appear increases the chance for a complete recovery.

Chloramphenicol may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.

Chloramphenicol may reduce the number of clot-forming cells (platelets) in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.

Diabetes patients - Chloramphenicol may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.

LAB TESTS, including complete blood cell counts, may be performed to monitor your progress or check for side effects. Be sure to keep all doctor and lab appointments.

Use Chloramphenicol with extreme caution in children younger 1 year. Safety and effectiveness in this age group have not been confirmed.

Use Chloramphenicol with extreme caution in children younger 10 years who have diarrhea or a stomach or bowel infection.

Use Chloramphenicol with extreme caution in premature and full-term infants because they may be more sensitive to the effects of Chloramphenicol, especially the risk of "gray syndrome."

Pregnancy and breast-feeding: If you become pregnant while taking Chloramphenicol, discuss with your doctor the benefits and risks of using Chloramphenicol during pregnancy. Chloramphenicol should be used with extreme caution during full-term pregnancy and labor because the fetus may experience severe side effects. Chloramphenicol is excreted in breast milk. Do not breastfeed while taking Chloramphenicol.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Mild diarrhea, nausea, or vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; dark urine; delirium; depression; headache; fever, chills, or sore throat; pain, redness, or swelling at the injection site; symptoms of "gray syndrome" in an infant (swelling of the abdomen, pale or blue skin color, vomiting, shock, difficulty breathing, refusal to suck, loose green stools, limp muscles, low temperature); unusual bleeding or bruising; unusual tiredness; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Hidantal Indication, Action Of Hidantal, Interactions, Hidantal

Hidantal [in more detail]

Hidantal Indication:

For the control of generalized tonic-clonic (grand mal) and complex partial (psychomotor, temporal lobe) seizures and prevention and treatment of seizures occurring during or following neurosurgery.

Hidantal Mechanism Of Action:

Hidantal acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. By promoting sodium efflux from neurons, phenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. This includes the reduction of post-tetanic potentiation at synapses. Loss of post-tetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas.

Hidantal Drug Interactions:

Food Interactions:

Avoid alcohol. Take with food. Do not take calcium, aluminum, magnesium or Iron supplements within 2 hours of taking this medication.

Comprar Diurefar (Lasix) Sin Receta, Diurefar

compra Diurefar (Lasix) en linea sin receta

Diurefar (Lasix) Explicacion

foco Diurefar en que realmente la batalla hacia demasiado edema (retencion de liquidos) a causa de un problema renal (sindrome nefrotico), fallo cardiovascular, cirrosis, asi como enfermedades en el higado. Adicionalmente, se utiliza en el tratamiento de la hipertension (hipertension).

funciones Diurefar por parar contra la asimilacion de sodio. Realmente es diuretico.

Diurefar tambien puede ser referido como furosemida, furosemida, Frusenex, Frusid, Frusol, Frudix, Furosedon.

titulo general asociada con Diurefar es en realidad furosemida.

Marca asociada con Diurefar Diurefar es en realidad.

Diurefar (Lasix) Dosis

Diurefar viene en:

40mg Baja Dosis material de friccion

100mg material de friccion dosis regular

Diurefar viene en pastillas, asi como el formulario de contacto fluido.

La dosis real asociado con Diurefar depende de su peso corporal y la posicion del cuerpo.

Obtener pastillas Diurefar, asi como el formulario de contacto de fluidos por via oral con o sin comidas.

Obtener Diurefar simultaneamente diario cada manana o incluso dos veces al dia cada manana y el medio dia actual, junto con el agua potable.

Por lo general, no moler o incluso masticar esto.

Si usted desea lograr mejores resultados por lo general no dejar de usar Diurefar, de repente.

Diurefar (Lasix) Careciendo asocia con dosis

Por lo general, no reciben doble dosis. En caso de que salte la dosis que necesita para llevar una vez se tiene en cuenta en lo que respecta a su deficiente. Cuando es hora de la dosis que necesita para llevar a cabo su propia rutina de dosificacion normal.

Diurefar (Lasix)

En el caso de que una sobredosis de Diurefar y que tambien se evita gran usted necesita comprobar hacia fuera su medico o incluso el medico de inmediato. Asociado con Diurefar sobredosis: desmayo, zumbido en los oidos, los malentendidos, alguna debilidad, mareos, hambre insuficiente.

Diurefar (Lasix) Espacio de almacenamiento

Tienda en temperaturas de espacio entre 10 y 30 niveles de D (59, asi como ochenta y seis niveles F) de la humedad, la iluminacion, asi como la temperatura. Fortalecer cualquier tipo de medicamento sin tocar a partir del dia de vencimiento. Mantener desde el lograr de los ninos.

Diurefar (Lasix) Efectos negativos

Diurefar ofrece los efectos negativos. El mas tipico tienden a ser:

arterial baja material de friccion menor presion

material de friccion mareo

material de friccion congestion

material de friccion de hormigueo sensacion

Material vientre molestias friccion

material de friccion vision borrosa

hormigueo material de friccion

material de friccion malentendidos

material de friccion migrana

material de friccion diarrea

Mucho menos tipicos y graves efectos negativos en toda utilizando Diurefar:

reaccion alergica respuestas (urticaria, inhalando y exhalando cuestiones, alergia, asi como la erupcion) material de friccion

nauseas o vomitos material de friccion

vomitando material de friccion

zumbido en el material de friccion oidos

material de friccion ictericia

sensacion material de friccion con sueno

demasiado la falta de material de friccion de peso corporal

taburetes de color arcilla material de friccion

corazon rapido batir material de friccion

sensibilidad hacia el material de friccion de iluminacion

material de friccion deseo demasiado

un poco de material de friccion debilidad

material de friccion bajo recuento de sangre

material de friccion pis oscuro

material de friccion hambre insuficiente

problemas con pis material de friccion

amigdalas doloridos material de friccion

sangrado simple o material de friccion moretones

masa muscular calambres material de friccion

material de friccion menor temperatura

material de friccion area de la boca seca

Los efectos negativos son indicaciones se basan en medicamentos que podrian estar utilizando pero, ademas, se basan en su condicion de bienestar y otros aspectos.

Diurefar (Lasix) Contraindicaciones

Por lo general no reciben Diurefar en caso de que son sensibles con el fin de Diurefar elementos.

Por lo general no reciben Diurefar si usted esta esperando otra manera tiene la intencion de tener un hijo, si no que realmente eres una mama medica. Danos Diurefar su hijo.

Utilizar Diurefar cuidadosamente en caso de que usted esta usando indometacina (tales porque Indocin); medicamentos esteroides (por ejemplo, porque prednisona); medicamentos para la diabetes; pastillas para bajar de peso; sucralfato (como porque Carafate); netilmicina (tales porque Netromycin), amikacina (tales porque Amikin), estreptomicina, tobramicina (tales porque Nebcin, Tobi), gentamicina (como ya Garamycin); digoxina (tales porque Lanoxin); medicamentos para la presion arterial baja; salicilatos (como la aspirina, porque, Tricosal, Disalcid, Dolobid, Salflex, pildoras de Doan); medicaciones frias; litio (tales porque Lithobid, Eskalith), acidez etacrinico (Edecrin porque tales); probenecid (por ejemplo porque Benemid).

Tenga cuidado junto con Diurefar en caso de que se ven afectados y tienen una breve historia asociada con la enfermedad renal, enfermedades en el higado, dolor de la gota, Laupus, diabetica.

Por lo general no reciben Diurefar o bien en condiciones de ir al bano.

Este medicamento en particular puede hacer que la piel mucho mas delicada hacia el sol. Por lo tanto intentar proteger la piel.

Mantengase alejado de la deshidratacion.

Si usted quiere tener un tratamiento quirurgico sea cauteloso junto con Diurefar.

Mantener Diurefar de ninos y no hacer esto algunas otras personas con respecto a la utilizacion.

Por lo general, no dejar de usar Diurefar, de repente.

Diurefar (Lasix) Preguntas comunes

Queen: ?Que es exactamente Diurefar?

El: foco en Diurefar es en realidad la batalla hacia demasiado edema (retencion de liquidos) a causa de un problema renal (sindrome nefrotico), fallo cardiovascular, cirrosis, asi como enfermedades en el higado. Ademas se utiliza en el tratamiento de la hipertension (hipertension).A

Queen: ?Cuales son exactamente los efectos negativos Diurefar?

El: Diurefar ofrece los tipicos efectos negativos, por ejemplo: presion inferior arterial baja, mareo, congestion, hormigueo de sensaciones, malestar vientre, vision borrosa, hormigueo, malentendidos, migrana, diarrea. Sin embargo en la situacion que se asocia con el rechazo asociado con componentes Diurefar que son capaces de encontrar efectos negativos mas graves: nauseas o vomitos, vomitos, zumbido en los oidos, ictericia, sensacion de sueno, demasiada falta de peso corporal, taburetes de color arcilla, rapida latido del corazon, la sensibilidad hacia la iluminacion, demasiado deseo, alguna debilidad, bajo recuento de sangre, orina oscuro, el hambre insuficiente, problemas con orinar, dolor en las amigdalas, sangrado o moretones facil, calambres de la masa muscular, la temperatura mas baja, asociada con la respuesta de reaccion alergica ( urticaria, problemas con la inhalacion y la exhalacion, la inflamacion, cierre), se seco la boca espectacular zona

Queen: ?Cuales son exactamente general, asi como las marcas asociadas con Diurefar?

El: titulo general asociada con Diurefar es en realidad furosemida. Marca asociada con Diurefar es en realidad Diurefar. A

comprar Diurefar (Lasix) en linea, Diurefar (Lasix) comprar en linea sin receta, Diurefar (Lasix) comprar sin receta, comprar barato Diurefar (Lasix), Diurefar (Lasix) comprar sin receta, comprar Diurefar (Lasix) de Canada, comprar Diurefar (Lasix) Canada, Para Diurefar (Lasix) en linea, Para Diurefar (Lasix) Generico Sin Receta Medica, Diurefar (Lasix) orden sin receta, Pildora por via oral Diurefar (Lasix)

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Cargill Our Company - Our Businesses - Cargill Meat Solutions, Carvil

Cargill Meat Solutions

Cargill Meat Solutions is the umbrella organization of Cargill’s North American beef. turkey. foodservice and food distribution businesses. Our main offices in Wichita, Kansas provide a central location from which we can serve our customers from coast-to-coast. And, it places us in America's agricultural heartland. Our businesses based in Wichita provide wholesome, high quality, nutritious and flavorful products to customers ranging from foodservice operators and grocery stores, to food manufacturers and export markets. These businesses employ more than 32,000 people in the U. S. and Canada, who work at dozens of processing and support facilities. These businesses focus on product innovation and quality, food safety, animal wellbeing, improved sustainability and community engagement.

In Wichita, many employees are active in the local community through its Cargill Cares Wichita team.

Businesses

The following businesses operate under the umbrella of Cargill Meat Solutions.

Terms of sale

Purchasing terms

Customer login

Consumer inquiries

Consumers can contact us with questions about the following brands:

Angus Pride®

Castle Wood Reserve®

Cedar Canyon®

Circle T Beef®

Emmber™

Excel®

Fairview Farms®

Good Nature®

Harvest Provisions™

Honeysuckle White®

Marval™

Maverick®

Meadowland Farms®

Morton's of Omaha®

Our Certified™

Plantation™

Prairie Ridge

Pride of the Farm™

Preferred Angus®

Riverside®

Rumba®

Schweigert™

Shady Brook Farms®

Silver T Brand®

Sterling Silver®

Tender Choice®

Tender Ridge®

Valley Tradition®

Willow Brook®

Diflucan - Anti Fungal, Diflazon

Product Description Common use Diflucan is an anti-fungal antibiotic which is used to treat fungal infections called candidiasis. This medication is prescribed for the treatment of such type of infections as vaginal, throat and fungal infections, infections of the urinary tract, peritonitis, and pneumonia. Diflucan works by killing sensitive fungi by interfering with the formation of the fungal cell membrane.

Dosage and direction Take it orally once a day, with or without food using the measuring spoon. Take it at the same time each day with a full glass of water if you want to get the best result. Diflucan make you feel better after 24 hours. However, your symptoms will go away completely just after few days. If there is no change in your health after a few days consult your doctor immediately. The dosage for adults may vary from type of infection: 1) Genital thrush - 150mg as a single dose 2) Mucosal thrush - dose depends on where the infection is located 50mg once daily during month. 3)Fungal skin infections - 50mg once daily for 2-4 weeks ; 4) Internal fungal infections 400mg on the first day then 200-400mg once daily for 6-8 weeks or longer if needed. 5) To stop you from getting fungal infections - 50-400mg once daily while you have risk to get an infection; 6) To stop infection caused by Cryptococcus from coming back - 100-200mg once daily indefinitely The dosage for children 4 weeks to 15 years old may also vary from type of infection: 1) mucosal infections - 3mg/kg once daily; 2)internal fungal infections - 6-12mg/kg once daily; 3)prevention of fungal infections - 3-12mg/kg once daily while at risk of getting an infection. For children 2-4 weeks old it is same dose as above but given once every 2 days. A maximum dose of 12mg/kg every 2 days. For children less than 2 weeks old it is same dose as above but given once every 3 days. Do not give more then 12mg/kg every 3 days. Note: this instruction presented here is just for review. It's very necessary to consult your doctor before using. It will help you to get best results.

For vaginal yeast infections, doctors usually prescribe a single dose of Diflucan. If the yeast infection does not improve after 5 days, contact your doctor as soon as possible. Be careful with this medication if your medical history include liver disease or kidney disease. Although uncommon, this drug may make you dizzy, so be more attentive while you are driving or using machinery. Limit alcohol intake. Diflucan should not be used during pregnancy, lactation or if you plan to become pregnant without a doctor's advice. Do not use before breast-feeding without a doctor's advice.

Contraindications Diflucan is not allowed to people who have hypersensitivity to Fluconazole or other anti fungal azole preparations, eg clotrimazole, ketoconazole, itraconazole and other. Also Diflucan contraindicated in: Kidney and liver disorders; Cardiovascular diseases including heart diseases(heart rate or rhythm disturbances); Low blood levels of calcium, magnesium or potassium.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include: nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); fever, chills, body aches, flu symptoms; severe blistering, peeling, and red skin rash; easy bruising or bleeding, unusual weakness; or seizure (convulsions). Less serious include: mild nausea, vomiting, diarrhea, or upset stomach; headache; dizziness; unusual or unpleasant taste in your mouth; or skin rash or itching. If you experience one of them stop using Diflucan and tell your doctor as soon as possible. Also consult your doctor about any side effect that seems unusual.

Drug interaction Diflucan interact with such medication as: a blood thinner such as warfarin (Coumadin) cyclosporine (Gengraf, Sandimmune, Neoral); an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others; rifabutin (Mycobutin) or rifampin (Rifadin, Rifater, Rifamate, Rimactane); a sedative such as diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), or midazolam (Versed); seizure medication such as phenytoin (Dilantin) or valproic acid (Depakene); tacrolimus ((Prograf); theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin, others). Also note that interaction between two medications does not always mean that you must stop taking one of them. Usually it affects the the effect of drugs, so consult your doctor about the way these interactions are being managed or should be managed.

Missed dose If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usual dose next day in the same time.

Overdose Symptoms of Diflucan overdose may include: confusion or unusual thoughts or behavior. If you experience one of them call your doctor immediately.

Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Difelene Price Compare, Aspizone

Difelene

Difelene is used for:

Managing mild to moderate pain. It is also used to manage pain caused by arthritis. It may also be used for other conditions as determined by your doctor. Difelene is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Do NOT use Difelene if:

you are allergic to any ingredient in diclofenac

you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or another NSAID (eg, ibuprofen, celecoxib)

you have recently had or will be having bypass heart surgery

you have severe kidney problems

you are in the last 3 months of pregnancy

Contact your doctor or health care provider right away if this applies to you.

Domina Pharmaceuticals, Erythrogel

Erythro - Gel Antibiotic for Skin Infections and Acne Treatment

Composition: Each 100g contains 4g erythromycin.

Indications: Erythro-Gel is a macrolide antibiotic. It interferes with bacterial protein synthesis and has a bacteriostatic or bactericidal effect. Its effect depends on its concentration and bacterial type. It has efficiency against most of gram-positive bacteria. Erythro-Gel is indicated in the treatment of impetigo, wound and burn infections, infected eczema, sycosis vulgaris and acne vulgaris and it is good tolerated by skin. It has the capability of good absorption and penetration to the follicles of sebaceous ducts. It reduces the bacterial colonies in the comedones and its metabolism products. Erythro-Gel gives good results in the case of infected acne vulgaris. It achieves the removal of pustule formation stage but it hasn’t any effect on the preformed pustules.

Usage: Erythro-Gel is for external use only. It is applied to the affected area twice daily after washing with warm water and soap and get completely dry. Acne lesions on the face, neck, and back can be treated with Erythro-Gel by using enough quantity to cover the affected area.

Side Effects: Cases of dryness, pruritis, tenderness, desquamation, erythema and feeling of burning have been reported.

Contraindications: Erythro-Gel is contraindicated in case of hypersensitivity to erythromycin.

Precautions: Erythro-Gel should be kept away from eyes, mouth and mucous membranes. The concomitant topical acne therapy should be applied with caution, because cumulative irritation effect may occur especially with the peeling and desquamating agents.

Use in Pregnancy and Lactation: Erythro-Gel could be used during pregnancy or lactation.

Resistance against Erythromycin: Resistance against erythromycin by staphylococci and streptococci is usually combined with cross-resistance against other antibiotics of macrolide type. This resistance does not appear usually during short period of therapy, but occurs on long termed therapy.

Presentation: Carton pack contains aluminum tube of 30g, with leaflet.

Retimax Ocular Electrophysiology, Retimax

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We are certified under the international ISO 9001:2008 standard for the quality of our services. We are also pleased to announce that we are the first and only Health Unit in Greece that has the specvialized quality certificate EN15224:2012 for the quality management of our medical services.

TAG CLOUD

RETIMAX OCULAR ELECTROPHYSIOLOGY - CSO

Retimax Optical Electrophysiology:

Retimax is the latest device for early glaucoma detection (CSO pending). It performs an objective test, based on the electrophysiology of the eye, useful for the functional assessment of the retinal cells. It is a complete electrophysiological system, capable of performing electroretinography (ERG), with “Flash” and “Flicker” stimulation, Pattern ERG (PERG), visual evoked potentials in occipital lobe “VEP” with “Flash” and “Pattern” stimulation, as well as SWEP ERG, electrooculography “EOG” with automatic operational protocol “Arden Ration”, electronystagmography (ENG). It uses cutting edge technology and is capable of providing statistical data related to the age of patients for ERG, PERG, VEP and EOG, portable dome “Miniganfield” for ERG and VEP, ideal for children or bedridden patients, as well as “Multifocal” ERG, PERG and VEP.

?????????????

We are certified under the international ISO 9001:2008 standard for the quality of our services. We are also pleased to announce that we are the first and only Health Unit in Greece that has the specvialized quality certificate EN15224:2012 for the quality management of our medical services.

TAG CLOUD

RETIMAX OCULAR ELECTROPHYSIOLOGY - CSO

Retimax Optical Electrophysiology:

Retimax is the latest device for early glaucoma detection (CSO pending). It performs an objective test, based on the electrophysiology of the eye, useful for the functional assessment of the retinal cells. It is a complete electrophysiological system, capable of performing electroretinography (ERG), with “Flash” and “Flicker” stimulation, Pattern ERG (PERG), visual evoked potentials in occipital lobe “VEP” with “Flash” and “Pattern” stimulation, as well as SWEP ERG, electrooculography “EOG” with automatic operational protocol “Arden Ration”, electronystagmography (ENG). It uses cutting edge technology and is capable of providing statistical data related to the age of patients for ERG, PERG, VEP and EOG, portable dome “Miniganfield” for ERG and VEP, ideal for children or bedridden patients, as well as “Multifocal” ERG, PERG and VEP.

Baligluc, Baligluc

Why register with MediGuard?

We are a free monitoring service designed for patients like you who want to be in the driver seat of your medical treatment. We have a community of more than 2.6 million members and offer the services below.

Medication Information Personalized Risk Rating Easy to understand overview Serious Side Effects Printable Medication List

Information you can understand Overview on Safety Alerts & Recalls Overview of Medications & Conditions

Community of patients Members’ Feedback Members Treatment Satisfaction

Health condition information Easy to understand overview Commonly Used Medications

Safety checks Safety Alerts & Recalls Drug - Drug Interaction Drug - Condition Interaction

Research participation Option to participate in medical surveys & studies*

Metformin (Metformin)

What is your Risk Rating for this medicine?

The risk of serious side effects for taking this medicine can be different if you take other medicines or if you suffer from a condition. Get your Risk Rating by creating a profile in a few steps.

Benefits:

We monitor your health and alert you to any safety updates and recalls.

You get to talk directly to other members about their experience.

You can create profiles for you and your loved ones.

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Share your story! Tell us how MediGuard has helped you or someone you love. Download the MediGuard Mobile App to manage your prescription and over-the-counter medications, for free. Taking multiple medications puts you at risk for possible drug-drug interactions Monitor the medical treatment of you and your loved ones.

DISCLAIMER: MediGuard is not intended to be a substitute for professional medical advice. MediGuard cannot and does not take into consideration every possible interaction or account for individual responses to medicine. Different individuals may respond to medication in different ways. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective, or appropriate for any given patient. Always seek the advice of a qualified health provider with any questions you may have before making any changes to your treatment. The use of the MediGuard site and its content is at your own risk. The MediGuard site and the information contained in it is intended for users in the United States and information in other countries may be different.

© Quintiles 2016

Cilex Side Effects, Cilex

Cilex Side Effects

Cilex is a commonly prescribed antibiotic that is used to treat bacterial infections within the body. Like any medication, Cilex can cause some side effects. These are usually minimal and do not cause most patients to discontinue use of Cilex.

What is Cilex?

Cilex is the brand name for a generic form of the antibiotic prescription drug cephalexin. Cilex belongs to a family of medications known as cephalosporins, which work by inhibiting the reproduction of bacteria within the body, thus alleviating infections.

For What Is Cilex Used?

Cilex is used for a variety of bacteria-caused infections within the body. It is most commonly prescribed for infections of the throat, lungs, tonsils, nose, ears, skin, bladder and kidneys, although it may be prescribed for other reasons as directed by your doctor.

What Aare the Common Side Effects Associated with Cilex?

There are several common side effects associated with Cilex usage. These can be exacerbated by increased doses, so be sure to take the medication exactly as prescribed for your specific condition.

The common side effects include diarrhea, upset stomach, dizziness, sleepiness, itching of the vagina or whiteness of the tongue. Vaginal and mouth symptoms are usually the result of a yeast infection or thrush--a yeast infection of the mouth. Since antibiotics kill off all bacteria within the body (even the "good" bacteria that typically keep yeast levels in check), yeast infections can occur and can be alleviated by also taking an anti-fungal medication if needed.

What Are the Severe Side Effects of Cilex?

If you should experience bloody stool or diarrhea, a severe rash on the body, swelling of the hands, face or tongue, difficulty swallowing or breathing, swelling of the joints, fever or yellowing of the skin or eyes, head to the nearest emergency room or call 911. These are symptoms of allergic reaction and/or liver dysfunction, both of which can be life-threatening if left untreated.

Contraindications

If you've ever had an allergic reaction to any medications (especially antibiotics), foods or food additives; are taking metformin or Glucophage; have a history of kidney, liver or bowel disease; have a bleeding disorder, colitis or carnitine deficiency; are pregnant or plan on becoming pregnant; or are breast-feeding, consult with your physician before taking Cilex.

Your physician can help you determine if the risks of Cilex are worth the benefits if you choose to take the drug.

References

Cilex

Photo Credit "Twitter 365 Project - Day 11" is Copyrighted by Flickr user: lu_lu (Luis Markovic) under the Creative Commons Attribution license.

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According to SteadyHealth. com, most doctors recommend that their patients cease alcohol consumption when taking just about any medication, including antibiotics.

Side Effects of Cephalexin 500 mg. Side Effects of Amias;. Serviflox Side Effects; Cilex Side Effects; Side Effects of Amias;.

Cephalexin is a commonly prescribed medication to fight all types of bacteria infections, including ear, skin, respiratory and throat infections. It belongs.

Cephalexin, an antibiotic, is often used to treat bacterial infections--including tooth abscess. Dentists prescribe Cephalexin for an infected tooth or an abscessed.

It is available in injectable form, capsules and oral solution. Cilex Side Effects; ehow. com. About eHow; eHow Blog; How to by.

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Antibiotics are one of the most important tools in modern medicine, easily stopping in their tracks many bacterial infections that in centuries.

Kilnits Crema Crema Lavable Para Que Sirve, Kilnits

KILNITS CREMA Crema Lavable

Precaucion con mayores de 2 anos

Revise siempre que no sea alergico a ninguno de los componentes de KILNITS CREMA Crema Lavable . podria poner en peligro su salud

Recuerda antes de tomar este medicamento consultar siempre con su medico, la informacion que ofrecemos es orientativa y no sustituye en ningun caso la de su medico u otro profesional de la salud.

Prospecto e indicaciones

Composicion:

Cada 100 ml de crema lavable contiene: Permetrina 1 g.

Indicaciones:

Kilnits crema lavable al 1% se utiliza para eliminar los piojos de la cabeza de adultos y ninos mayores de 2 anos.

Accion Terapeutica:

Modo de Empleo:

Usar solo externamente, no ingerir. Este producto se aplica sobre el cabello seco. Agitar bien el frasco antes de usar. Aplicar la crema directamente sobre la cabellera seca (no se debe mojar el cabello antes de aplicar el producto). Aplicar en cantidad suficiente (30 ml) para saturar el cabello y el cuero cabelludo, especialmente detras de las orejas y en la nuca. Friccionar ligeramente evitando el contacto con los ojos. Dejar permanecer la crema en el cabello durante 6 horas como minimo sin usar secador de pelo (usar gorro protector para evitar el contacto con la ropa). Enjuagar con agua tibia sin champu. Lavar con champu y secar el cabello solo 24 horas despues de la aplicacion de Kilnits crema lavable. Remover los piojos y liendres con el peine. Un solo tratamiento es suficiente para eliminar los piojos y liendres de la cabeza, solo excepcionalmente se requiere repetir el tratamiento a los 7 dias. Este tratamiento debe ser aplicado a todas las personas de la casa aunque aparentemente no tengan piojos ni liendres.

Presentaciones:

Envase conteniendo 100 ml con peine de arrastre incluido y gorro protector.

TIBIA . Es el mas largo de los huesos existentes entre la rodilla y el tobillo y el que soporta casi todo el peso.

Ketoconazol Topico Medlineplus Medicinas, Ketazol

Ketoconazol topico

?Para cuales condiciones o enfermedades se prescribe este medicamento?

La crema de ketoconazol se usa para tratar la tinea corporis (tina, tina corporal; infeccion fungica de la piel que causa sarpullido (erupciones en la piel) escamoso rojizo en diferentes partes del cuerpo), tinea cruris (tina crural o inguinal; infeccion fungica de la piel en la zona de la ingle o las nalgas), tinea pedis (pie de atleta; infeccion fungica de la piel de los pies y entre los dedos de los pies), tinea versicolor (tina versicolor; infeccion fungica que provoca manchas de color marron o amarillo claro en el torax, espalda, brazos, piernas, o cuello) e infecciones por levadura de la piel. El champu de ketoconazol prescrito se usa para tratar la tina versicolor. El champu de ketoconazol sin prescripcion se usa para controlar la descamacion, exfoliacion y el prurito (picazon) del cuero cabelludo causado por la caspa. El ketoconazol pertenece a una clase de medicamentos llamados imidazoles antifungicos. Funciona al frenar el crecimiento de los hongos que causan la infeccion.

?Como se debe usar este medicamento?

El ketoconazol prescrito viene envasado en forma de crema y champu para aplicar sobre la piel. El ketoconazol sin prescripcion viene envasado en forma de champu para aplicar al cuero cabelludo. La crema de ketoconazol por lo general se aplica 1 vez al dia durante 2 a 6 semanas. El champu de ketoconazol prescrito por lo general se aplica 1 vez para tratar la infeccion. El champu de ketoconazol sin prescripcion generalmente se usa cada dias 3 a 4 por hasta 8 semanas y luego se usa segun sea necesario para controlar la caspa. Siga cuidadosamente las instrucciones en la etiqueta del medicamento y preguntele a su doctor o farmaceutico cualquier cosa que no entienda. Use el medicamento exactamente como se indica. No use mas ni menos que la dosis indicada ni tampoco mas seguido que lo prescrito por su doctor.

Un solo tratamiento con champu de ketoconazol prescipto puede combatir con exito una infeccion de tina versicolor. Sin embargo, puede tomar varios meses antes de que el color de su piel se normalice, especialmente si su piel esta expuesta a la luz solar. Despues de que la infeccion sea tratada, existe la posibilidad de que usted vuelva a tener una infeccion de tina versicolor.

Si usted esta usando el champu de ketoconazol sin prescripcion para tratar la caspa, sus sintomas deben mejorar durante las primeras 2 a 4 semanas del tratamiento. Llame a su doctor si sus sintomas no mejoran durante este tiempo o si sus sintomas empeoran en cualquier momento durante el tratamiento.

Si usted esta usando la crema de ketoconazol, sus sintomas deben mejorar desde el comienzo de su tratamiento. Siga usando la crema de ketoconazol aunque se sienta bien. Si deja de usar la crema de ketoconazol demasiado pronto, su infeccion puede no curarse completamente y sus sintomas pueden regresar.

La crema de ketoconazol y los champus son solo para uso sobre la piel o el cuero cabelludo. No deje que la crema o el champu de ketoconazol entren a sus ojos o a la boca y no trague este medicamento. Si la crema o el champu de ketoconazol entran a sus ojos, lavese con mucha agua.

Para usar la crema, aplique suficiente cantidad para cubrir la zona afectada y toda la piel alrededor.

Para usar el champu de prescripcion, siga estos pasos:

Con poca agua moje la piel en el area donde aplicara el champu de ketoconazol.

Aplique el champu en la piel afectada y en un area amplia alrededor.

Use sus dedos para frotar el champu hasta que se forme espuma.

Deje que el champu permanezca sobre la piel durante 5 minutos.

Enjuague el champu con agua.

Para usar el champu sin prescripcion, siga estos pasos:

Asegurese de que su cuero cabelludo no esta lastimado, cortado, o irritado. No use el champu de ketoconazol si su cuero cabelludo esta lastimado o irritado.

Moje su cabello a fondo.

Aplique el champu en el cabello.

Use sus dedos para frotar el champu hasta que se forme espuma.

Enjuague el cabello con mucha agua para sacar todo el champu.

Repita los pasos 2 a 5.

?Que otro uso se le da a este medicamento?

La crema y el champu de ketoconazol prescrito tambien se usan a veces para tratar la caspa y la dermatitis seborreica (condicion que causa descamacion de la piel). La crema de ketoconazol se usa a veces para tratar la tinea manuum (infeccion fungica de la piel de las manos). La crema de ketoconazol tambien se usa a veces con otros medicamentos para tratar las afecciones de la piel que a menudo han empeorado por la infeccion fungica, como la dermatitis de panal, el eccema (irritacion de la piel causada por alergias), el impetigo (ampollas causadas por una infeccion bacteriana) y la psoriasis (una afeccion cronica de la piel que puede durar toda la vida). Converse con su doctor acerca de los riesgos de usar este medicamento para tratar su condicion.

Este medicamento tambien puede ser prescrito para otros usos; pidale mas informacion a su doctor o farmaceutico.

?Cuales son las precauciones especiales que debo seguir?

Antes de comenzar a usar ketoconazol:

digale a su doctor y a su farmaceutico si usted es alergico al ketoconazol o a otros medicamentos, cremas o champus. Si usted esta usando la crema, digale a su doctor si es alergico a los sulfitos.

digale a su doctor y a su farmaceutico que medicamentos con y sin prescripcion esta tomando, como por ejemplo vitaminas, suplementos nutricionales y productos fabricados a base de hierbas. Su doctor podria cambiar la dosis de su medicamento o vigilarle cuidadosamente para detectar la aparicion de efectos secundarios.

digale a su doctor si usted tiene o alguna vez ha tenido trastornos medicos. Si usted esta usando la crema, digale a su doctor si tiene o alguna vez ha tenido asma.

digale a su doctor si esta embarazada, tiene planes de quedar embarazada o si esta amamantando. Si queda embarazada mientras usa este medicamento, llame a su doctor de inmediato.

?Que dieta especial debo seguir mientras tomo este medicamento?

Si alguien traga la crema o el champu de ketoconazol, llame a la oficina local de control de envenenamiento al 1-800-222-1222. Si la victima esta inconsciente, o no respira, llame inmediatamente al 911.

Betaderm Side Effects In Detail, Betaderm

Betaderm Side Effects

Note: This page contains information about the side effects of betamethasone topical. Some of the dosage forms included on this document may not apply to the brand name Betaderm.

For the Consumer

Applies to betamethasone topical: topical application cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by betamethasone topical (the active ingredient contained in Betaderm). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking betamethasone topical:

More common:

Burning, itching, or stinging at the application site

Less common:

Hair loss

thinning of the hair

Incidence not known:

Blistering, burning, crusting, dryness, or flaking of the skin

irritation

itching, scaling, severe redness, soreness, or swelling of the skin

redness and scaling around the mouth

thinning of the skin with easy bruising, especially when used on where the skin folds together (e. g. between the fingers)

Minor Side Effects

Some of the side effects that can occur with betamethasone topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Acne or pimples

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

Incidence not known:

Burning and itching of the skin with pinhead-sized red blisters

burning, itching, and pain in hairy areas, or pus at the root of the hair

increased hair growth on the forehead, back, arms, and legs

lightening of normal skin color

lightening of treated areas of dark skin

reddish purple lines on the arms, face, legs, trunk, or groin

softening of the skin

For Healthcare Professionals

Applies to betamethasone topical: topical cream, topical foam, topical gel, topical lotion, topical ointment, topical spray

General

The most commonly reported side effects were pruritus, burning, itching, irritation.

Hypersensitivity

Rare (less than 0.1%): Hypersensitivity

Endocrine

Frequency not reported: Cushing's syndrome [Ref ]

Dermatologic

Common (1% to 10%): Pruritus Uncommon (0.1% to 1%): Folliculitis, skin infections (including bacterial, fungal and viral skin infections) Frequency not reported: Dryness, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae, miliaria [Ref ]

Local

Uncommon (0.1% to 1%): Application site pain Frequency not reported: Burning, itching, irritation [Ref ]

Ocular

Rare (less than 0.1%): Eye disorder [Ref ]

Metabolic

Frequency not reported: Hyperglycemia

Renal

Frequency not reported: Glucosuria

Other

Rare (less than 0.1%): Rebound effect

References

1. Ruiz-Maldonado R, Zapata G, Lourdes T, Robles C "Cushing's syndrome after topical application of corticosteroids." Am J Dis Child 136 (1982): 274-5

2. "Product Information. Diprolene (betamethasone topical)." Schering Laboratories, Kenilworth, NJ.

3. Flynn MD, Beasley P, Tooke JE "Adrenal suppression with intranasal betamethasone drops." J Laryngol Otol 106 (1992): 827-8

4. Stoppoloni G, Prisco F, Santinelli R, Sicuranza G, Giordano C "Potential hazards of topical steroid therapy." Am J Dis Child 137 (1983): 1130-1

5. Stevens DJ "Cushing's syndrome due to the abuse of betamethasone nasal drops." J Laryngol Otol 102 (1988): 219-21

6. Walsh P, Aeling JL, Huff L, Weston WL "Hypothalamus-pituitary-adrenal axis suppression by superpotent topical steroids." J Am Acad Dermatol 29 (1993): 501-3

7. Reymann F, Kehlet H "Hypothalamic-pituitary-adrenocortical function. Association with topical application of betamethasone dipropionate." Arch Dermatol 115 (1979): 362-3

8. Salde L, Lassus A "Systemic side-effects of three topical steroids in diseased skin." Curr Med Res Opin 8 (1983): 475-80

9. Cunliffe WJ, Burton JL, Holti G, Wright V "Hazards of steroid therapy in hepatic failure." Br J Dermatol 93 (1975): 183-5

10. Macdonald A "Topical corticosteroid preparations. Hazards and side-effects." Br J Clin Pract 25 (1971): 421-5

11. Smith EB, Breneman DL, Griffith RF, Hebert AA, Hickman JG, Maloney JM, Millikan LE, Sulica VI, Dromgoole SH, Sefton J, et al "Double-blind comparison of naftifine cream and clotrimazole/betamethasone dipropionate cream in the treatment of tinea pedis." J Am Acad Dermatol 26 (1992): 125-7

12. Grice K "Tinea of the hand and forearm. Betamethasone valerate atrophy." Proc R Soc Med 59 (1966): 254-5

13. Hellgren L "Induction of generalized pustular psoriasis by topical use of betamethasone-dipropionate ointment in psoriasis." Ann Clin Res 8 (1976): 317-9

14. Ellis CN, Katz HI, Rex IH Jr, Shavin JS, Van Scott EJ, VanderPloeg D "A controlled clinical trial of a new formulation of betamethasone dipropionate cream in once-daily treatment of psoriasis." Clin Ther 11 (1989): 768-74

15. Sneddon I "Perioral dermatitis." Br J Dermatol 87 (1972): 430-4

16. Barkey WF "Striae and persistent tinea corporis related to prolonged use of betamethasone dipropionate 0.05% cream/clotrimazole 1% cream (Lotrisone cream)." J Am Acad Dermatol 17 (1987): 518-9

17. Butcher JM, Austin M, McGalliard J, Bourke RD "Bilateral cataracts and glaucoma induced by long term use of steroid eye drops." BMJ 309 (1994): 43

18. Eisenlohr JE "Glaucoma following the prolonged use of topical steroid medication to the eyelids." J Am Acad Dermatol 8 (1983): 878-81

19. Kitazawa Y "Increased intraocular pressure induced by corticosteroids." Am J Ophthalmol 82 (1976): 492-5

Not all side effects for Betaderm may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here .

Buy Storilat Carbamazepine Online Without Prescriptions, Storilat

Tegretol (carbamazepine) is an anticonvulsant. It works by decreasing nerve impulses that cause seizures and pain. Tegretol is used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy. Carbamazepine is also used to treat bipolar disorder. Tegretol may also be used for purposes not listed in this medication guide.

Take Tegretol exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release Tegretol tablet. Swallow the pill whole. Breaking the pill would cause too much of the drug to be released at one time.

Shake the Tegretol oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and call your doctor promptly if this medicine seems to stop working as well in preventing your seizures. Tegretol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill.

To be sure Tegretol is not causing harmful effects, your blood cells and kidney function may need to be tested often. Do not miss any follow up visits to your doctor for blood or urine tests. Your doctor may also recommend having your eyes checked regularly while you are taking this medicine.

Do not stop using Tegretol without first talking to your doctor, even if you feel fine. You may have increased seizures or unpleasant withdrawal symptoms if you stop using this medicine suddenly. Wear a medical alert tag or carry an ID card stating that you take Tegretol. Any medical care provider who treats you should know that you take seizure medication.

Store this medicine at room temperature away from moisture, heat, and light.

Active Ingredient: Carbamazepine

Tegretol may cause severe or life-threatening skin rash, especially in people of Asian ancestry. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction. Seek emergency medical attention if you have a fever, sore throat, headache and skin pain, followed by a red or purple skin rash that spreads and causes blistering and peeling.

You should not take Tegretol if you have a history of bone marrow suppression, if you are also taking nefazodone, or if you are allergic to an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor).

Tegretol may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant while taking Tegretol for seizures. Do not start or stop taking Tegretol during pregnancy without your doctor's advice.

Before you take Tegretol, tell your doctor if you have heart disease, high blood pressure, high cholesterol, liver or kidney disease, glaucoma, a thyroid disorder, lupus, porphyria, or a history of mental illness or psychosis.

You may have thoughts about suicide while taking Tegretol. Your doctor will need to check you at regular visits. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

There are many other drugs that can interact with Tegretol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Do not stop using Tegretol without first talking to your doctor, even if you feel fine. You may have increased seizures or unpleasant withdrawal symptoms if you stop using Tegretol suddenly.

Do not use Tegretol if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. You should not take Tegretol if you are allergic to carbamazepine, or if you have:

a history of bone marrow suppression

if you are also taking nefazodone; or

if you are allergic to an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor).

Important safety information:

Tegretol may cause severe or life-threatening skin rash, especially in people of Asian ancestry. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction.

To make sure you can safely take Tegretol, tell your doctor if you have any of these other conditions:

heart disease, high blood pressure, high cholesterol or triglycerides;

liver or kidney disease;

a thyroid disorder;

a history of mental illness or psychosis.

Patients of Asian ancestry may have a higher risk of developing a rare but serious skin reaction to Tegretol. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

You may have thoughts about suicide while taking Tegretol. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed. Seizure control is very important during pregnancy. The benefit of preventing seizures may outweigh any risks posed by taking Tegretol. Follow your doctor's instructions about taking Tegretol while you are pregnant.

FDA pregnancy category D. Tegretol may cause harm to an unborn baby. Do not start taking this medcine without telling your doctor if you are pregnant or planning to become pregnant. Use effective birth control while you are taking this medicine. Although Tegretol may harm an unborn baby, having a seizure during pregnancy could harm both mother and baby. If you become pregnant while taking Tegretol, do not stop taking the medicine without your doctor's advice.

Carbamazepine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using Tegretol. Carbamazepine can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking Tegretol.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid drinking alcohol. It can increase some of the side effects of Tegretol, and can also increase your risk of seizures.

Avoid exposure to sunlight or tanning beds. Tegretol can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Grapefruit and grapefruit juice may interact with Tegretol and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

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Bendit, planchas de asar.

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Lubexyl, Lubexyl

Permamed international

Permamed is an independent Swiss pharmaceutical company with head offices at CH-4106 Therwil, close to Basel (Switzerland), active in the development, the manufacturing and the marketing of pharmaceutical specialities.

It was founded in the year 1979 by Christian Lutz and employs today about 60 persons in Switzerland. Permamed has its own galenical development and production department as well as affiliate companies with distribution and licence partners in various contries.

During the last 30 years, Permamed has established itself successfully on the Swiss market with its pharmaceutical preparations of innovative character for the treatment of skin diseases, rheumatism, sports injuries and vein diseases.

Our skin-cleansing emulsions for treatment and prophylaxis of skin diseases as well as for intimate hygiene are market leaders in Switzerland. Our products and services contribute to therapeutic success and to an increased quality of life. Numerous new introductions form the basis of the positive development of the last few years.

A well-trained scientific sales staff is securing a permanent exchange of experience with our partners in hospitals and private clinics, in pharmacies and drugstores as well as in paramedical circles. We organize specific conferences and teaching seminars.

For exportation to a few chosen countries the dermatological products Der-med, Lubex, Lubexyl, Squa-med, Lubex hair, Lubex femina, Lubex peeling, Lubex lotion plus and our new Lubex anti-irritation shampoo are available. There is also the possibility to order Permamed products through an International pharmacy such as the Victoria Apotheke in Zurich.

Furthermore you can find interesting information about our new and innovative dermatological anti-aging line: Read the Lubex anti-age brochure in English or visit the Lubex anti-age® website in English, German, French and Italian.

For more information about our export products or possible collaborations, please contact our export department (e-mail export(at)permamed. ch ).

We are looking forward hearing from you.

Products

Lipanthyl 200 Micronised Capsules, Lipanthyl

LIPANTHYL 200 MICRONISED CAPSULES

Transcript

PACKAGE LEAFLET: INFORMATION FOR THE USER

LIPANTIL MICRO 200/ LIPANTHYL 200 MICRONISED CAPSULES (fenofibrate) Read all of this leaflet carefully before you start taking this medicine. Keep this leaflet. You may need to read it again. If you have any further questions, ask your doctor. This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor. In this leaflet: 1. What Lipantil Micro is and what it is used for 2. Before you take Lipantil Micro 3. How to take Lipantil Micro 4. Possible side effects 5. How to store Lipantil Micro 6. Further information The name of your medicine is LIPANTIL MICRO 200/ LIPANTHYL 200 MICRONISED CAPSULES but will be referred to as Lipantil Micro throughout this leaflet. 1. WHAT LIPANTILMICRO IS AND WHAT IT IS USED FOR Lipantil Micro belongs to a group of medicines, commonly known as fibrates. These medicines are used to lower the level of fats (lipids) in the blood. For example the fats known as triglycerides. Lipantil Micro is used, alongside a low fat diet and other nonmedical treatments such as exercise and weight loss, to lower levels of fats in the blood. Lipantil Micro can be used in addition to other medicines [statins] in some circumstances when levels of fats in the blood are not controlled with a statin alone. Lipantil Micro can often also increase the amount of a ‘good’ type of cholesterol, called HDL or high density lipoprotein cholesterol. It is always essential to continue a low-fat diet during treatment with Lipantil Micro. 2. BEFORE YOU TAKE LIPANTIL MICRO Do not take Lipantil Micro if: You are allergic (hypersensitive) to fenofibrate, or any of the other ingredients of Lipantil Micro.

You suffer from liver or kidney disease or gallbladder disease. Sunlight or UV light have caused an allergic reaction (photoallergy) or skin damage while you were taking fibrates or an anti-inflammatory drug called ketoprofen in the past. You suffer from pancreatitis (inflammation of the pancreas leading to abdominal pain) unless it is caused by high levels of fat in the blood (hypertriglyceridemia) Take special care with Lipantil Micro Tell your doctor before you start to take this medicine: If you have any kidney problems. If you suffer from an under active thyroid gland (hypothyroidism). If you have diabetes, especially Type 2 diabetes, that is not well controlled. If you have liver problems. If you have problems with certain proteins in your blood. If you have an alcohol problem. You are taking other medicines. If you or your family have had muscle problems. If you are over 70 years of age. (some of the above conditions can lead to high levels of lipids in your blood and need to be corrected before you start therapy with fenofibrate). Your doctor might want to test your blood or urine to check if Lipantil Micro is working properly and also if your kidneys, muscles and liver are working properly. Important advice regarding muscle effects: Contact your doctor quickly if you experience unexplained muscle pain, tenderness or weakness. This is because on rare occasions, there is a risk of muscle problems which may be serious, including muscle breakdown which can cause kidney damage. Your doctor may perform a blood test to check the condition of your muscles before and after starting treatment. The risk of muscle breakdown is greater in certain patients. Tell your doctor if any of the following applies to you: You have any kidney problems An under active thyroid You often drink large amounts of alcohol You have ever had muscle problems during treatment with cholesterol lowering medicines called ‘statins’ (such as simvastatin, atorvastatin, pravastatin, rosuvastatin or fluvastatin) or fibrates (such as fenofibrate, bezafibrate or gemfibrozil) You or close family members have a hereditary muscle disorder

The risk of muscle problems can be greater if Lipantil Micro is taken with cholesterol lowering medicines called ‘statins’ (such as simvastatin, atorvastatin, pravastatin, rosuvastatin, fluvastatin). Tell your doctor if you are taking any of these medicines. Taking other medicines Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. In particular please let your doctor know if you already take: Anticoagulants to thin your blood (for example, warfarin). Other drugs to control lipid (fat) levels in the blood (for example, drugs known as ‘statins’ or ‘fibrates’). Taking a ‘statin’ (e. g. simvastatin, atorvastatin) at the same time as Lipantil Micro can increase the risk of muscle problems. Ciclosporin (an immunosuppressant). Drugs to control Type 2 diabetes (glitazones). Pregnancy and breast-feeding Pregnancy Tell your doctor if you are, you think you might be or are planning to become pregnant. Lipantil Micro must not be taken if you are pregnant. Breast-feeding You must not use Lipantil Micro if you are breast-feeding or if you are planning to breastfeed your baby. Driving and using machines This medicine should not affect your ability to drive or use machines. Important information about some of the ingredients of Lipantil Micro This medicine contains lactose which is a type of sugar. If you have been told by your doctor that you have a intolerance to some sugars, contact your doctor before taking this medicinal product. 3. HOW TO TAKE LIPANTIL MICRO Always take Lipantil Micro exactly as your doctor has told you. Also, please read the label on the packet. You should check with your doctor if you are not sure. Swallow the capsule whole with a glass of water. It is important to take the capsule with food, as it will not work as well if your stomach is empty. The usual dose for adults is one capsule of Lipantil Micro a day, taken at mealtimes. Use in children and adolescents Lipantil Micro is not recommended for use in children under the age of 18.

People with kidney problems If you have kidney problems, your doctor may tell you to take a lower dose. Ask your doctor or pharmacist about this. If you take more Lipantil Micro than you should If you accidentally take more Lipantil Micro than you should or if someone else has taken your medicine, contact your nearest hospital casualty department or tell your doctor immediately. If you forget to take Lipantil Micro Do not take a double dose to make up for a forgotten capsule. Take the next dose with your next meal and then carry on taking your capsules as usual. If you are worried about this talk to your doctor. If you stop taking Lipantil Micro Do not stop taking the medicine unless your doctor tells you to, or your medicine makes you feel unwell. This is because raised cholesterol levels need treating for a long period of time. Remember you should also continue with a low-fat diet whilst taking Lipantil Micro. If your doctor stops your medicine, do not keep any left over capsules unless your doctor tells you to. If you have any further questions on the use of this product, ask your doctor. 4. POSSIBLE SIDE EFFECTS Like all medicines, Lipantil Micro can cause side effects, although not everybody gets them. Some patients have experienced the following side effects whilst taking fenofibrate: Common (in less than 1 in 10, but more than 1 in 100 patients treated): Stomach pain, being sick, feeling sick, diarrhoea and wind (flatulence) Raised levels of various liver enzymes in the blood Uncommon (in less than 1 in 100, but more than 1 in 1,000 patients treated): Pancreatitis (inflammation of the pancreas leading to stomach pain) Blood clot in the lung causing chest pain and breathlessness (pulmonary embolism); blood clot in the leg causing pain, redness or swelling (deep vein thrombosis) Gallstones (cholelithiasis) Headache Reactions such as rashes, itching or red patches on the skin Muscle pain, muscle inflammation, muscle cramps, spasms or weakness Reduced sex drive

Slight increases in blood levels of substances normally excreted by the kidneys (creatinine) Rare (in less than 1 in 1,000, but more than 1 in 10,000 patients treated): Slight increases in substances excreted by the kidneys (urea) Hair loss Increased sensitivity to light Decrease in haemoglobin (oxygen carrying pigment in blood) and decrease in white blood cells Hepatitis (inflammation of the liver), symptoms of which may be mild jaundice (yellowing of the skin and whites of the eyes), stomach pain and itching In addition to those events reported during clinical trials, the following side effects have been reported spontaneously during postmarketing use of Lipantil Micro. A precise frequency cannot be estimated from the available data and is therefore classified as ‘not known’: Muscle breakdown Chronic disease of the lung tissues Fatigue Vertigo Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at:www. mhra. gov. uk/yellowcard By reporting side effects, you can help provide more information on the safety of this medicine. 5. HOW TO STORE LIPANTIL MICRO. Do not store above 25°C. Store in the dry place and protected from light. Keep out of the sight and reach of children. Remember if your doctor tells you to stop taking this medicine, return any unused tablets to your pharmacist for safe disposal. Only keep this medicine if your doctor tells you to. If the capsules become discoloured or show any other signs of deterioration, seek the advice of your pharmacist. Do not use this medicine after the expiry date which is stated on the carton and the blister pack after ‘Exp’. The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. FURTHER INFORMATION What Lipantil contains The active ingredient in Lipantil micro is fenofibrate. Each capsule contains 200mg of fenofibrate. The other ingredients are: lactose, magnesium stearate, pregelatinised maize starch, sodium lauryl sulphate, crospovidone, titanium dioxide (E171), iron oxide (E172) erythrosine (E127) and gelatin. What Lipantil looks like and contents of the pack Lipantil micro is a plain orange capsule Lipantil Micro is available as blister packs of 30 capsules. Manufactured by: Recipharm Fontaine, Rues des Prets Potets, 21121 Fontaine-les-Dijon, France. Procured from within the EU and repackaged by the Product Licence holder: B&S Healthcare, Unit 4, Bradfield Road, Ruislip, Middlesex, HA4 0NU, UK. LIPANTIL MICRO 200/ LIPANTHYL 200 MICRONISED CAPSULES: POM PL: 18799/2586 Leaflet revised: 10.08.2015

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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Calcium Carbonate (Novalucol)

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of the body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Calcium carbonate works best if you take it with food. Swallow the calcium carbonate tablet or capsule with a full glass of water.

The chewable tablet should be chewed before you swallow it.

Use the calcium carbonate powder as directed. Allow the powder to dissolve completely, then consume the mixture. Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Store at room temperature away from moisture and heat.

If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Usual Adult Dose for Osteoporosis:

2500 to 7500 mg/day orally in 2 to 4 divided doses.

Usual Adult Dose for Hypocalcemia:

900 to 2500 mg/day orally in 2 to 4 divided doses. This dose may be adjusted as needed to achieve a normal serum calcium level.

Usual Adult Dose for Dyspepsia:

300 to 8000 mg/day orally in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease symptoms of stomach upset. Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Adult Dose for Duodenal Ulcer:

1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of calcium carbonate is gastric hypersecretion and acid rebound.

Usual Adult Dose for Gastric Ulcer:

1250 to 3750 mg/day in 2 to 4 divided doses. This dose may be increased as needed and tolerated to decrease the abdominal discomfort. The major limiting factor to the chronic use of calcium carbonate is gastric hypersecretion and acid rebound.

Usual Adult Dose for Erosive Esophagitis:

1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents. Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Adult Dose for Gastroesophageal Reflux Disease:

1250 to 3750 mg/day orally in 2 to 4 divided doses. The potential for acid rebound could be detrimental. However, antacids have been frequently used in the management of erosive esophagitis and may be beneficial in decreasing the acidity of gastric contents. Maximum Dose: 5,500 to 7980 mg (depending on product used). Not to exceed maximum daily dosage for a period of greater than 2 weeks unless directed by a physician.

Usual Pediatric Dose for Hypocalcemia:

Neonatal: Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium: 50 to 150 mg/kg/day in 4 to 6 divided doses; not to exceed 1 g/day

Usual Dosage: Antacid: Children 2 to 5 years: Childrens Pepto, Mylanta (R) Childrens: 1 tablet (400 mg calcium carbonate) as symptoms occur; not to exceed 3 tablets/day Children 6 to 11 years: Childrens Pepto, Mylanta (R) Childrens: 2 tablets (800 mg calcium carbonate) as symptoms occur; not to exceed 6 tablets/day Children 11 years and older: Tums (R), Tums (R) E-X: 2 to 4 tablets chewed as symptoms occur; not to exceed 15 tablets [Tums (R)] or 10 tablets [Tums (R) E-X] per day Tums (R) Ultra: 2 to 3 tablets chewed as symptoms occur; not to exceed 7 tablets per day Hypocalcemia (dose depends on clinical condition and serum calcium level): Dose expressed in mg of elemental calcium: Children: 45 to 65 mg/kg/day in 4 divided doses

Store Calcium Carbonate at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep Calcium Carbonate out of the reach of children and away from pets.

Calcium carbonate is a chemical compound with the formula CaCO3.

Do not use Calcium Carbonate if you are allergic to any ingredient in Calcium Carbonate.

Do not take calcium carbonate or antacids that contain calcium without first asking your doctor if you also take other medicines. Calcium can make it harder for your body to absorb certain medicines. Calcium carbonate works best if you take it with food.

To make sure you can safely take calcium carbonate, tell your doctor if you have any of these other conditions:

a history of kidney stones;

a parathyroid gland disorder.

Talk to your doctor before taking calcium carbonate if you are pregnant. Talk to your doctor before taking calcium carbonate if you are breast-feeding a baby.

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Calcium Carbonate. Seek medical attention right away if any of these SEVERE side effects occur when using Calcium Carbonate:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.

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A team for products and services full of contents.

Being able to listen and wanting to understand are the basic conditions for an effective and efficient customer service . The application of this concept transforms the Isopan team in a real value for Clients.

We invest in technology looking to the future

Isopan produces and commercialises metal faced insulating panels for roofs and walls with a high isothermal coefficient for public, industrial, commercial and agricultural constructions.

Produce and respect the environment

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Isopan has two production plants in Italy . one in Patrica (Frosinone) and the other one in Trevenzuolo (Verona). Isopan's production plants in Europe are: Isopan Iberica in Spain (Tarragona), Isopan Est in Bucarest (Rumania), Isopan Deutschland in Halle (Germany) and Isopan RUS in Volgograd (Russia).

Some Isopan projects, an example of quality

Isopan catalogues

The technical information in PDF format. If you do not have Acrobat Reader, click here to download it (it is a free software).

Thecnical documentation

Isopan technical specifications were born out of the desire to help the client/designer choose the type of product that best suits their constructions and standards related needs.

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Lidocain Injektion wird verwendet, um einen Bereich des Korpers zu helfen, Schmerzen zu lindern oder Beschwerden durch invasive medizinische Verfahren wie Chirurgie, Nadelstiche oder Insertion eines Katheters oder Atemschlauch verursacht betauben.

Lidocain Injektion wird auch in einer epidural (Spinalanasthesie) gegeben, um die Beschwerden der Kontraktionen wahrend der Wehen zu reduzieren.

Lidocain Injektion wird manchmal verwendet, um Herzrhythmusstorungen, die eine mogliche Herzinfarkt hindeuten konnen, zu behandeln.

Lidocain Injektion kann auch fur andere Zwecke, die nicht in dieser Anleitung Medikamente verwendet werden.

Lidocain wird als Injektion durch eine Nadel in eine Vene oder direkt in den Body-Bereich zu betaubt platziert gegeben. Ihr Arzt, Krankenschwester oder andere Gesundheitsdienstleister wird Ihnen diese Injektion. Ihre Atmung, Blutdruck, Sauerstoffgehalt und andere Vitalparameter wird genau beobachtet werden, wahrend Sie erhalten Lidocain Injektion in einem Krankenhaus.

Um Herzrhythmusstorungen zu behandeln, kann Ihnen gezeigt, wie Sie Ihre Medizin zu Hause verwenden. Nicht selbst injizieren das Medikament, wenn Sie nicht vollstandig verstehen, wie die Injektion und ordnungsgema? von Nadeln und andere Gegenstande im Geben der Medizin verwendet entsorgen.

Die LidoPen Auto-Injektor ist ein vorgefullten automatische Injektionsvorrichtung im Notfall verwendet werden. Halten Sie das Gerat mit Ihnen zu allen Zeiten. Ihr Arzt wird beschreiben, die Anzeichen und Symptome zu suchen, wenn die Entscheidung, wann es Zeit ist, die Injektion verwendet sehen. Verwenden Sie niemals die LidoPen Auto-Injektor, ohne zuerst mit Ihrem Arzt.

Verwenden Sie nicht die Auto-Injektor in oder in der Nahe einer Vene oder in das Gesa?. Spritzen Sie das Medikament nur in Ihrer Oberschenkel oder Oberarm.

Mit dem LidoPen Autoinjektor erhalten Sie auch eine CardioBeeper. Dieses Gerat wird verwendet, um Ihre Herzfrequenz und Rhythmus mit Ihrem Arzt uber eine Telefonleitung ubertragen. Lesen Sie alle mitgelieferten Anleitungen und Praxis mit dem CardioBeeper, so dass Sie in der Lage sein, schnell verwenden Sie es in einem Notfall.

Verwenden Lidocain als von Ihrem Arzt verordnet

Bewahren Sie die LidoPen Autoinjektor bei Raumtemperatur weg von Feuchtigkeit und extremer Hitze oder Kalte.

Sie sollten nicht diese Medikation, wenn Sie allergisch auf Lidocain oder jede andere Art von Betaubung Medizin sind.

Wenn Sie eines dieser anderen Bedingungen haben, mussen Sie moglicherweise eine Dosisanpassung oder spezielle Tests zur sicheren Verwendung Lidocain-Injektion:

koronarer Herzkrankheit, Durchblutungsstorungen oder

eine Geschichte der malignen Hyperthermie.

FDA Schwangerschaft Kategorie B. Dieses Medikament ist nicht zu erwarten, als schadlich fur ein ungeborenes Kind. Informieren Sie Ihren Arzt, wenn Sie schwanger sind oder planen, wahrend der Behandlung schwanger werden. Es ist nicht bekannt, ob Lidocain-Injektion in die Muttermilch oder ob es ein Saugling schaden konnte passiert. Verwenden Sie nicht diese Medikation ohne erzahlen Sie Ihren Arzt, wenn Sie stillen ein Baby.

Wichtige Informationen zur Sicherheit

Moglicherweise gibt es andere Medikamente, die mit Lidocain Injektion interagieren konnen. Informieren Sie Ihren Arzt uber alle verschreibungspflichtigen und OTC-the-counter Medikamente, die Sie verwenden. Dazu gehoren Vitamine, Mineralien, pflanzliche Produkte, Medikamente und durch andere Arzte. Beginnen Sie nicht mit einem neuen Medikament ohne Rucksprache mit Ihrem Arzt.

Erhalten Sie Notfall medizinische Hilfe, wenn Sie eines dieser Anzeichen einer allergischen Reaktion: Nesselsucht, Atembeschwerden, Schwellungen von Gesicht, Lippen, Zunge oder Rachen. Informieren Sie Ihren Betreuer sofort, wenn Sie irgendwelche dieser ernsten Nebenwirkungen haben:

Angstgefuhle, wackelig, schwindlig, unruhig oder depressiv;

Schlafrigkeit, Erbrechen, Ohrensausen, Sehstorungen;

Verwirrung, Zuckungen, Krampfe (Krampfanfalle);

schneller Herzschlag, schnelle Atmung, Gefuhl hei? oder kalt;

schwach oder flache Atmung, langsamer Herzschlag, schwacher Puls, oder

Gefuhl, wie Sie konnte gehen.

Weniger schwerwiegende Nebenwirkungen gehoren:

mild Blutergusse, Rotung, Juckreiz oder Schwellungen, wo das Medikament injiziert wurde;

Taubheit in Orten, wo das Medikament versehentlich angewendet wird.

Dies ist keine vollstandige Liste der Nebenwirkungen und andere auftreten.

Rufen Sie Ihren Arzt fur die medizinische Beratung uber Nebenwirkungen.

About Citem, Citom

About CITEM

The Center for International Trade Expositions and Missions (CITEM) is the export promotion arm of the Philippine Department of Trade and Industry (DTI). CITEM is committed to developing, nurturing, and promoting globally-competitive small and medium enterprises (SMEs), exporters, designers, and manufacturers by implementing an Integrated Approach to Export Marketing in partnership with other government and private entities.

CITEM's 2016 Calendar of Events

CITEM's 2017 Calendar of Events

Interior Design Magazine, the leading and most influential publication of the North American ?design? and contract industry, features Design Philippines brands as emerging designers in the recently concluded International Contemporary Furniture Fair New York (ICFF NY): Kenneth Cobonpue, Schema, LIJA by That One Piece, and Zarate Manila.

Watch Interior Design Magazine editor-in-chief Cindy Allen presents the Emerging Designers at ICFF NY.

Manila FAME The Design and Lifestyle Event

Considered as the country's premier design and lifestyle event, Manila FAME is a bi-annual showcase of craftsmanship, design innovation, and artisanship in Philippine products. It features finely selected furniture and home furnishings, holiday gifts and décor, and fashion accessories designed and crafted in the Philippines for the global market.

Organized by the Philippine Department of Trade and Industry (DTI), through the Center for International Trade Expositions and Missions (CITEM), Manila FAME is the second-longest running trade show in the Asia Pacific. It is the only trade event in the country approved by the Union des Foires Internationales (UFI), or the Global Association of the Exhibition Industry, a Paris-based association of trade fair organizers founded 90 years ago in Milan, Italy, on 15 April 1925.

Objects define individuals and cultures.

Objects build bridges that connect people and time.

Objects are ideas transformed into tangible realities.

Adding beauty and meaning to life.

2016 International Events

Prevex B, Prevex B

Pharmacy

Health + Wellness

Exclusives

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Prescription Drugs

Prevex B

PREVEX B 0.1% CREAM

How does this medication work? What will it do for me?

Betamethasone valerate belongs to the class of medications called topical corticosteroids. It is used to treat skin irritation and itch caused by skin conditions such as eczema, psoriasis, contact dermatitis, and seborrhea. It works by reducing redness, inflammation, swelling, and irritation of the skin.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

How should I use this medication?

Cream or ointment: Apply enough cream or ointment to completely cover the affected area with a thin film. Massage it gently and thoroughly into the skin. This medication is usually applied once daily in the morning, or twice daily (in the morning and at night) as directed by the doctor. The treatment should be stopped when the condition is cleared. The medication should not be continued for a period longer than 4 weeks without further consultation with your doctor.

Lotion: Apply a few drops of lotion or enough to thinly cover the affected area. The lotion should be gently massaged into the area until it disappears. The lotion is usually applied once or twice.

Wash your hands after applying this medication unless you are treating your hands.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

Shake the lotion well before applying it to the affected area.

Do not cover the area with an occlusive dressing (a dressing that doesn't breathe) unless directed to do so by your doctor.

Avoid applying the medication in or near the eyes.

It is important to use this medication exactly as prescribed by your doctor. If you miss an application, apply it as soon as possible and continue with your regular schedule. If it is almost time for your next application, skip the missed application and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep out of reach of children.

Do not dispose of medications in wastewater (e. g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?

Each gram of cream contains betamethasone valerate 1.22 mg equivalent to 1 mg or 0.1% betamethasone in an anhydrous base. Nonmedicinal ingredients: dimethicone, microcrystalline wax, trisiloxane and petrolatum.

Who should NOT take this medication?

Do not use this medication if you:

are allergic to betamethasone or any ingredients of the medication

have a skin infection caused by viruses, including herpes simplex, vaccinia, and varicella (chickenpox)

have had an allergic reaction to other corticosteroid medications

have untreated infected skin lesions caused by an infection with fungi or bacteria

have tuberculosis of the skin

Do not apply this medication around the mouth, to the eye, or on or around the anal and genital area.

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

burning, dryness, irritation, itching, or redness or skin (usually mild and temporary)

skin rash (usually mild and temporary)

stinging sensation when applied (lotion only)

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

increased skin sensitivity

lack of healing of skin condition

ongoing burning, itching and irritation of skin

itchy rash with small, red, raised bumps

skin discolouration

skin infection

"spider veins" or blood vessels visible through the skin

thinning of skin with easy bruising

Additional side effects may occur if this medication is used improperly or for long periods of time. Check with your doctor as soon as possible if any of the following side effects occur:

acne or oily skin

backache

blurring or loss of vision (occurs gradually if medication has been used near the eye)

changes in skin colour

depression

eye pain (if medication has been used near the eye)

filling or rounding out of the face

increased blood pressure

increased hair growth, especially on the face and body

increased loss of hair, especially on the scalp

irregular heartbeat

irregular menstrual periods

irritability

loss of appetite

muscle cramps, pain, or weakness

nausea

pus in the hair follicles

rapid weight gain or loss

reddish purple lines on arms, face, legs, trunk, or groin

redness and scaling around the mouth

softening of the skin

stomach bloating, burning, cramping, or pain

swelling of feet or lower legs

tearing of the skin

thinning of skin with easy bruising

unusual bruising

unusual decrease in sexual desire or ability (in men)

unusual tiredness or weakness

vomiting

weakness of the arms, legs, or trunk (severe)

white spots

worsening of infections

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Absorption: Topical (applied to the skin) corticosteroids such as betamethasone are known to be absorbed into the bloodstream, especially if used for prolonged periods of time on large areas of the body. It is advisable to use betamethasone for brief periods of time only and to stop using it as soon as the problem clears.

Eyes: Use this medication with caution on lesions close to the eye. Take care to ensure that it does not enter the eye, as glaucoma or cataracts may result. Report any changes in your vision to your doctor, as soon as possible.

Infections: Betamethasone should not be used on any infected area until the infection has cleared. Corticosteroids applied to the skin may increase the risk of developing a skin infection. If you notice any increased redness, swelling, heat, or pain around the area where the medication is applied, contact your doctor, as these are possible signs of infection.

Stopping this medication: Suddenly stopping corticosteroid medication may cause your skin condition to return. If you have been using this medication for a long period of time, discuss with your doctor the best way to discontinue the medication.

Thinning of skin: Using topical corticosteroid medication for a long period of time can cause skin and the tissues underneath to thin or soften, or cause stretch marks. Your doctor may recommend you stop using this medication once in a while or to apply to one area of the body at a time to give the skin a chance to strengthen. If you notice changes to the texture or colour of your skin contact your doctor as soon as possible.

Pregnancy: Betamethasone should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using this medication, contact your doctor immediately.

Breast-feeding: It is not known if betamethasone applied to the skin passes into breast milk. If you are a breast-feeding mother and are using this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding. If this medication is used, it should not be applied to the breast in order to avoid the baby getting this medication in their mouth.

Children: Betamethasone belongs to the family of medications known as corticosteroids . Children may be more likely to experience side effects (e. g. slowing down of growth, delayed weight gain), especially if large amounts of this medication are used for long periods of time. The use of this medication by children should be limited to the smallest amount that will be effective for the shortest period of time. Discuss the risks and benefits of the use of this medication by children with your doctor.

What other drugs could interact with this medication?

There may be an interaction between betamethasone and any of the following:

itraconazole

medications applied to the skin that have irritating effects

other topical medications that contain corticosteroids

natalizumab

pimecrolimus

ritonavir

tacrolimus

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

stop taking one of the medications,

change one of the medications to another,

change how you are taking one or both of the medications, or

leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material © 1996-2016 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Extoxnet Pip, Difonate

The information in this profile may be out-of-date. It was last revised in 1996. EXTOXNET no longer updates this information, but it may be useful as a reference or resource.

Please visit the National Pesticide Information Center (NPIC) to find updated pesticide fact sheets. If you don't find a fact sheet related to your question, feel free to call 1-800-858-7378. NPIC is open five days a week from 8:00am to 12:00pm Pacific Time.

Extension Toxicology Network

Pesticide Information Profiles

A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Oregon State University, the University of Idaho, and the University of California at Davis and the Institute for Environmental Toxicology, Michigan State University. Major support and funding was provided by the USDA/Extension Service/National Agricultural Pesticide Impact Assessment Program.

EXTOXNET primary files maintained and archived at Oregon State University

Revised June 1996

Trade and Other Names : Trade names for fonofos include Capfos, Cudgel, Difonate, Dyfonate, Dyphonate, and Stauffer N 2790.

Regulatory Status : Fonofos is a highly toxic organophosphate insecticide in EPA toxicity class I. Labels for products containing it must bear the Signal Words DANGER - POISON. Some or all formulations of fonofos are classified as Restricted Use Pesticides (RUPs) by the EPA. RUPs may be purchased and used only by certified applicators.

Chemical Class . organophosphate

Introduction : Fonofos is a soil organophosphate insecticide primarily used on corn. It is also used on sugar cane, peanuts, tobacco, turf, and some vegetable crops. It controls aphids, corn borer, corn rootworm, corn wireworm, cutworms, white grubs, and some maggots. It is available in granular, microgranular, emusifiable concentrate, suspension concentrate, microcapsule suspension, and seed treatment.

Formulation . It is available in granular, microgranular, emulsifiable concentrate, suspension concentrate, microcapsule suspension, and seed treatment formulations.

Acute toxicity: Fonofos is highly toxic via the oral route, with reported oral LD50 values in male rats ranging from 6.8 to 18.5 mg/kg [2,28] and from 3.2 to 7.9 mg/kg in female rats [69]. It is also highly toxic via the dermal route with reported dermal LD50 values of 25 mg/kg in female rabbits, 147 mg/kg in rats, and 278 mg/kg in guinea pigs [2]. The inhalation toxicity is moderate with a reported 4-hour airborne LC50 of 0.9 mg/L [13]. Symptoms of fonofos exposure may be delayed from a few minutes to up to 12 hours after exposure. Early symptoms include blurred vision, headache, and dizziness. Skin contact often brings about sweating and muscle twitching. Eye contact causes tearing, pain, and blurring. Ingestion may cause nausea, abdominal cramps, and diarrhea [47]. Deaths resulting from high exposures are often due to respiratory arrest. While these effects are similar to those caused by other organophosphates, fonofos may cause them at lower doses than others. A number of human poisonings by fonofos have been recorded. One woman exposed orally to a large amount of fonofos, developed nausea, sweating, and respiratory arrest in addition to muscle twitching, low blood pressure and pulse rate, and pinpoint pupils. A pancreatic cyst (attributed to fonofos exposure) was located and drained externally in the course of her treatment. She recovered after 2 months of hospitalization [2].

Chronic toxicity: Chronic effects may be similar to those observed after acute exposure, with some delay [2,8]. In hens, administration of 90 oral doses of 8 mg/kg (at unspecified intervals) didn't produce delayed neurotoxicity [2]. Dietary feeding of fonofos at low levels to dogs for 14 weeks produced no effects at or below doses of 0.20 mg/kg [47].

Reproductive effects: A long-term reproduction test in rats showed no effects on female reproductive ability at doses of 2.0 mg/kg/day of fonofos [69,70]. This evidence suggests that fonofos does not cause reproductive effects.

Teratogenic effects: Pregnant mice were fed very high doses of fonofos during the sensitive period of gestation. At these levels, some abnormal bone development and brain changes were observed in the fetuses [69]. Teratogenic effects in humans are not likely under normal conditions.

Mutagenic effects: Fonofos was not mutagenic in five microbial assays nor in a DNA synthesis test using human cells [69] suggesting that it is not mutagenic.

Carcinogenic effects: Male and female rats which ingested very high daily doses (relative to the LD50) of fonofos for 2 years showed no cancerous effects [69].

Organ toxicity: Fonofos affects the eyes, respiratory system, and central nervous system.

Fate in humans and animals: Fonofos is readily absorbed through the skin, gastrointestinal tract, and respiratory tract [2]. Once absorbed it is systemically distributed. Fonofos is quickly excreted in animals; 96 hours after rats received a single, high oral dose of fonofos, three quarters of the dose was found in the urine, a third in the feces, a small amount in expired air, and only a trace in the tissues [71]. Virtually complete elimination occurred within 2 to 16 days after exposure [69]. In another study, rats given nearly pure fonofos excreted almost all of it within 4 days [69]. A fonofos product, Dyfonate, is broken down in rat livers into several metabolites, one of which is a potent cholinesterase inhibitor known as an oxon [69]. This also is rapidly eliminated. Other than the fonofos oxon (an anticholinesterase metabolite), fonofos' breakdown products are less toxic than the parent compound [2].

Effects on birds: Fonofos is highly toxic to birds, with a reported acute LD50 of 128 mg/kg in mallards [13]. Other reported LD50 values are 16.9 mg/kg in mallards, 12 to 14 mg/kg in northern bobwhite and 10 mg/kg in red-winged blackbirds [6]. It has a reported 5-day dietary LC50 of 284 ppm in Japanese quail [14]. Despite its high acute toxicity and widespread use, wildlife die-offs due to fonofos use have not been reported [14].

Effects on aquatic organisms: Fonofos is highly toxic to freshwater fish and saltwater organisms. Its acute freshwater 96-hour LC50 ranges from 0.028 mg/L [13] to 44 mg/L [72] in bluegill sunfish, and 0.05 mg/L [13] to 44 mg/L [72] in rainbow trout, perhaps reflecting a difference in formulation. Organophosphates, such as fonofos, do not bioaccumulate in the environment or in animals [1].

Effects on other organisms: Fonofos is toxic to bees [13].

Breakdown in soil and groundwater: Fonofos is of moderate persistence in soils with a field half-life of about 40 days [19]. Field residence times depend on variables such as soil type, organic matter, rainfall, and sunlight. On a silty clay loam, the half-life was 82 days after a high level of application, while at lower application rates the half-life was 46 days [73]. Fonofos is moderately well-bound to soils, depending on organic matter content [19]. It can be transported in runoff. It is immobile in sandy loam and silt loam soils, but is mobile in quartz sand. Soil microbes, such as fungi, rapidly degrade fonofos [73]. Fonofos resists soil leaching, and has been detected only rarely in groundwater and then at very low levels. Fonofos has been detected in California groundwater at 0.01 to 0.03 ug/L, and in Iowa groundwater at 0.1 ug/L [73].

Breakdown in water: Although it is practically insoluble in water, it is quickly broken down by hydrolysis [8,13].

Breakdown in vegetation: Fonofos is rapidly metabolized in plant tissues to nontoxic compounds [8]. The compound is not readily absorbed by plant foliage and it is not translocated throughout plants [8].

Appearance: Fonofos is a clear to yellow liquid at room temperature [13].

Chemical Name: O-ethyl S-phenyl (RS)-ethylphosphorodithioate [13]

CAS Number: 944-22-9

Molecular Weight: 246.32

Water Solubility: 13 mg/L [13]

Solubility in Other Solvents: v. s. in organic solvents like kerosene, xylene, and isobutyl methyl ketone [13]

Melting Point: Not Available

Vapor Pressure: 28 mPa @ 25 C [13]

Partition Coefficient: 3.9031 [13]

Adsorption Coefficient: 870 [19]

Zeneca Ag Products 1800 Concord Pike Wilmington, DE 19897

References for the information in this PIP can be found in Reference List Number 5

Suprelip

+ pribalovy‐letak. info

SUPRELIP

sp. zn. sukls93386/2011

SUPRELIP

200 mg, tvrde tobolky fenofibratum

Prectete si pozorne celou pribalovou informaci drive, nez zacnete tento pripravek uzivat, protoze obsahuje pro Vas dulezite udaje.

- Ponechte si pribalovou informaci pro pripad, ze si ji budete potrebovat precist znovu.

- Mate-li jakekoli dalsi otazky, zeptejte se sveho lekare nebo lekarnika.

- Tento pripravek byl predepsan vyhradne Vam. Nedavejte jej zadne dalsi osobe. Mohl by ji ublizit, a to i tehdy, ma-li stejne znamky onemocneni jako Vy.

- Pokud se u Vas vyskytne kterykoli z nezadoucich ucinku, sdelte to svemu lekari nebo lekarnikovi. Stejne postupujte v pripade jakychkoli nezadoucich ucinku, ktere nejsou uvedeny v teto pribalove informaci. Viz bod 4.

Co naleznete v teto pribalove informaci

1. Co je pripravek SUPRELIP a k cemu se pouziva

2. Cemu musite venovat pozornost, nez zacnete pripravek SUPRELIP uzivat

3. Jak se pripravek SUPRELIP uziva

4. Mozne nezadouci ucinky

5. Jak pripravek SUPRELIP uchovavat

6. Obsah baleni a dalsi informace

1. Co je pripravek SUPRELIP a k cemu se pouziva

Suprelip patri do skupiny lecivych pripravku obecne zvanych fibraty. Tyto lecive pripravky se uzivaji ke snizeni hladiny tuku (lipidu) v krvi, napr. tuku oznacovanych jako triglyceridy.

Suprelip se uziva ke snizeni hladiny tuku v krvi soucasne s dietou zamerenou na nizky prijem tuku a s dalsi nefarmakologickou lecbou, jako je cviceni a snizovani hmotnosti.

Suprelip se muze za urcitych okolnosti pouzivat spolecne s jinymi leky (statiny), a to tehdy, kdyz nejsou hladiny tuku v krvi samotnym statinem kontrolovany.

2. Cemu musite venovat pozornost, nez zacnete pripravek SUPRELIP uzivat

Neuzivejte pripravek SUPRELIP:

- jestlize jste alergicky(a) na fenofibrat nebo na kteroukoli dalsi slozku tohoto pripravku

- pri zavaznych poruchach funkce jater a onemocneni zlucniku

- pri zavaznych poruchach funkce ledvin

- v kombinaci s jinymi fibraty

- u deti a dospivajici do 18 let

- behem tehotenstvi a v prubehu kojeni

- pri fotoalergicke nebo fototoxicke reakci (kozni reakce po ozareni slunecnimi nebo UV paprsky) v prubehu lecby fenofibratem nebo latkou s podobnou strukturou, zejmena ketoprofenem (obsazen v protizanetlivych lecich)

- bez konzultace s lekarem nelze uzivat soucasne s fenofibratem jine leky snizujici hladinu cholesterolu (napr. tzv. statiny).

Upozorneni a opatreni

Pred uzitim pripravku SUPRELIP se poradte se svym lekarem nebo lekarnikem.

Pri lecbe pripravkem SUPRELIP je nutne pokracovat v diete, kterou Vam lekar doporucil.

Behem lecby se budete muset podrobovat pravidelnym lekarskym kontrolam a odberum krve v intervalech, ktere urci lekar.

Deti a dospivajici

Pripravek SUPRELIP neni urcen pro deti a dospivajici mladsi 18 let.

Dalsi lecive pripravky a pripravek SUPRELIP

Informujte sveho lekare nebo lekarnika o vsech lecich, ktere uzivate, ktere jste v nedavne dobe uzival(a) nebo ktere mozna budete uzivat. Ucinky pripravku SUPRELIP a ucinky jinych soucasne uzivanych leku se mohou vzajemne ovlivnovat. Nez zacnete soucasne s uzivanim pripravku SUPRELIP uzivat nejaky volne prodejny lek, poradte se se svym lekarem.

Pripravek SUPRELIP muze zesilit ucinky latek snizujicich krevni srazlivost, coz se projevi zvysenou krvacivosti. Muze zesilit i ucinek fenylbutazonu a ucinek tzv. peroralnich antidiabetik, tj. neinzulinovych pripravku, pouzivanych pri cukrovce ke snizovani hladiny krevniho cukru.

Pri kombinaci s latkami, ktere samy mohou pusobit nepriznive na jaterni funkce (napr. v kombinaci s tzv. inhibitory MAO), by snadno mohlo dojit k poruse jaternich funkci.

Obecne se nedoporucuje kombinovat toto lecivo se statiny (skupina leciv uzivanych rovnez pri lecbe hyperlipidemie - napr. lovastatin, simvastatin). Existuje zde riziko vyskytu toxickeho ucinku na svaly, zejmena v pripade jiz existujiciho onemocneni svalu.

Sledovany musi byt take ledvinne funkce pri soubeznem podavani fenofibratu a cyklosporinu (pripravku pouzivaneho k potlaceni imunitni (obranne) reakce), protoze muze dojit k docasnemu poskozeni funkce ledvin.

Tehotenstvi a kojeni

Pokud jste tehotna nebo kojite, domnivate se, ze muzete byt tehotna, nebo planujete otehotnet, poradte se svym lekarem nebo lekarnikem drive, nez zacnete tento pripravek uzivat.

V tehotenstvi se pripravek SUPRELIP uzivat nesmi. Otehotni-li zena v prubehu lecby, je nutne prerusit lecbu a informovat lekare.

V obdobi kojeni se rovnez pripravek SUPRELIP uzivat nesmi.

Rizeni dopravnich prostredku a obsluha stroju

Pripravek SUPRELIP nema vliv na schopnost ridit dopravni prostredky nebo obsluhovat stroje. Pripravek SUPRELIP obsahuje sacharozu

Pripravek obsahuje sacharozu (37,68 mg v jedne tobolce), a proto by jej nemely uzivat osoby se vzacne se vyskytujicimi poruchami metabolismu cukru (napr. nesnasenlivost fruktozy, poruchy vstrebavani glukozy a galaktozy apod.). Pokud Vam Vas lekar rekl, ze nesnasite nektere cukry, poradte se se svym lekarem, nez zacnete tento lecivy pripravek uzivat.

3. Jak se pripravek SUPRELIP uziva

Vzdy uzivejte tento pripravek presne podle pokynu sveho lekare nebo lekarnika. Pokud si nejste jisty(a), poradte se se svym lekarem nebo lekarnikem.

Davkovani

Pokud Vas lekar neurcil jinak, dodrzujte tento navod k uziti.

Pouziti u deti a dospivajicich

Bezpecnost a ucinnost fenofibratu u deti a dospivajicich mladsich 18 let nebyla stanovena. Nejsou k dispozici zadne udaje. Pouziti fenofibratu u pediatricke populace mladsi nez 18 let neni proto doporuceno.

Doporucena davka je 1 tobolka pripravku SUPRELIP denne.

Tobolky uzivejte jednou denne, cele, nerozkousane, behem nektereho z hlavnich jidel, vzdy ve stejnou denni dobu.

Pripravek SUPRELIP se uziva dlouhodobe. Tento lek predstavuje spolu s dietnim rezimem dlouhodobou symptomatickou lecbu, jejiz ucinnost musi byt pravidelne sledovana.

Jestlize jste uzil(a) vice pripravku SUPRELIP, nez jste mel(a)

Dosud nebyl u cloveka zaznamenan zadny pripad predavkovani timto lekem. Presto se pri poziti vetsi davky, nez Vam lekar predepsal nebo pri poziti leku ditetem, poradte se svym lekarem.

Jestlize jste zapomnel(a) uzit pripravek SUPRELIP

Nezdvojnasobujte nasledujici davku, abyste nahradil(a) vynechanou davku. Pokracujte v uzivani obvykle davky v obvyklou dobu, jako byste davku nevynechal(a).

4. Mozne nezadouci ucinky

Podobne jako vsechny leky muze mit i tento pripravek nezadouci ucinky, ktere se ale nemusi vyskytnout u kazdeho

Pripravek SUPRELIP se obvykle dobre snasi. Nezadouci ucinky jsou jen lehciho razu a projevuji se pouze vzacne (mohou se vyskytnout u 1 az10 osob z 10 000).

Mohou se objevit zazivaci obtize (nevolnost. pocit nuceni na zvraceni. bolesti v nadbrisku), kozni projevy, jako jsou vyrazka. koprivka, fotosenzitivita (kozni projevy na mistech vystavenych pusobeni slunecnich paprsku nebo UV zareni), prechodne zvyseni hladin transaminaz ( jaternich enzymu), bolesti svalu, bolesti hlavy, slabost, zavrate.

Informujte sveho lekare neodkladne v pripade bolesti svalu, zvysene bolestive citlivosti svalu a svalove slabosti, protoze tyto nezadouci ucinky mohou byt ve vzacnych pripadech zavazne.

Hlaseni nezadoucich ucinku

Pokud se u Vas vyskytne kterykoli z nezadoucich ucinku, sdelte to svemu lekari nebo lekarnikovi. Stejne postupujte v pripade jakychkoli nezadoucich ucinku, ktere nejsou uvedeny v teto pribalove informaci. Nezadouci ucinky muzete hlasit take primo na adresu:

Statni ustav pro kontrolu leciv Srobarova 48, 100 41 Praha 10

Nahlasenim nezadoucich ucinku muzete prispet k ziskani vice informaci o bezpecnosti tohoto pripravku.

5. Jak pripravek SUPRELIP uchovavat

Uchovavejte tento pripravek mimo dohled a dosah deti.

Nepouzivejte tento pripravek po uplynuti doby pouzitelnosti uvedene na obalu. Doba pouzitelnosti se vztahuje k poslednimu dni v mesici.

Pripravek SUPRELIP uchovavejte v puvodnim vnitrnim obalu, aby byl pripravek chranen pred vlhkosti.

Nevyhazujte zadne lecive pripravky do odpadnich vod nebo domaciho odpadu. Zeptejte se sveho lekarnika, jak nalozit s pripravky, ktere jiz nepouzivate. Tato opatreni pomahaji chranit zivotni prostredi.

6. Obsah baleni a dalsi informace

Co pripravek SUPRELIP obsahuje

- Lecivou latkou je fenofibratum 200 mg v 1 tvrde tobolce

- Pomocnymi latkami j sou zrneny cukr (sacharoza, kukuricny skrob), hypromelosa, natrium-lauryl-sulfat, dimetikonova emulze 35%, simetikonova emulze 30%, mastek

- Slozeni obalu tobolky: zelatina, zluty oxid zelezity (E172), oxid titanicity (E171)

Jak pripravek SUPRELIP vypada a co obsahuje toto baleni

Tvrde zelatinove tobolky s vrchni casti zlutou, nepruhlednou a spodni casti bezbarvou pruhlednou, obsahujici bile kulate mikrogranule.

Obsah baleni: 30 nebo 100 tobolek

Drzitel rozhodnuti o registraci

PharmaSwiss Ceska republika s. r.o. Praha, Ceska republika Vyrobce:

PharmaSwiss d. o.o. Ljubljana, Slovinsko

Tato pribalova informace byla naposledy revidovana 29.4.2015.

1. NAZEV PRIPRAVKU

200 mg, tvrde tobolky

2. KVALITATIVNI I KVANTITATIVNI SLOZENI

Fenofibratum 200 mg v l tvrde tobolce.

Pomocna latka se znamym ucinkem: 1 tvrda tobolka obsahuje 37,68 mg sacharozy. Uplny seznam pomocnych latek viz bod 6.1.

Tvrde tobolky Popis pripravku:

Tvrde zelatinove tobolky s vrchni casti zlutou, nepruhlednou a spodni casti bezbarvou pruhlednou, obsahujici bile kulate mikrogranule.

4. KLINICKE UDAJE

4.1 Terapeuticke indikace

SUPRELIP je indikovan jako doplnek k diete a jine nefarmakologicke lecbe (napr. cviceni, snizovani hmotnosti) v nasledujicich pripadech:

- lecba zavazne hypertriglyceridemie s nizkym HDL cholesterolem nebo bez nej.

- smisena hyperlipidemie, kdy je lecba statiny kontraindikovana nebo neni tolerovana.

- jako doplnek k lecbe statinem u smisene hyperlipidemie pacientu s vysokym kardiovaskularnim rizikem, u nichz triacylglyceroly ani HDL cholesterol nejsou dostatecne kontrolovany.

4.2 Davkovani a zpusob podani

Lecba pripravkem SUPRELIP vzdy v kombinaci s dietou je dlouhodoba a vyzaduje pravidelne kontroly hladin lipidu v seru.

Doporucena denni davka je 200 mg (tj. 1 tobolka) denne, ktera se uziva behem hlavniho jidla, protoze z prazdneho zaludku se pripravek SUPRELIP hure vstrebava. Po zavedeni lecby je nadale nezbytne dodrzovat dietni rezim.

U starsich pacientu bez poruchy funkce ledvin neni nutne obvykle davkovani upravovat.

Pri lecbe pripravkem SUPRELIP dochazi vetsinou k rychlemu poklesu hladin lipidu, ale pokud nedojde k adekvatni odpovedi na lecbu behem 3 mesicu, doporucuje se lecbu prerusit.

Bezpecnost a ucinnost fenofibratu u deti a dospivajicich mladsich 18 let nebyla stanovena. Nejsou k dispozici zadne udaje. Pouziti fenofibratu u pediatricke populace mladsi nez 18 let neni proto doporuceno.

4.3 Kontraindikace

Pripravek SUPRELIP se nesmi uzivat v techto pripadech:

• Hypersenzitivita na fenofibrat nebo na kteroukoli pomocnou latku uvedenou v bode 6.1

• Tezka porucha funkce ledvin

• T ezka porucha funkce j ater

• Vyskyt fotosenzitivni reakce behem uzivani fenofibratu nebo latek pribuznych (ketoprofen)

• Obdobi tehotenstvi a laktace

• Nedoporucuje se podavani pripravku SUPRELIP detem a dospivajicich do 18 let

• Nedoporucuje se kombinace s inhibitory HMG-CoA reduktazy anebo jinymi fibraty.

4.4 Zvlastni upozorneni a opatreni pro pouziti

Ucinek na svaly

V souvislosti s lecbou fibraty byly zaznamenany pripady poskozeni svalu vcetne vzacnych pripadu rhabdomyolyzy. Vyskyt teto poruchy se zvysuje u pacientu s hypoalbuminemii a ledvinnou nedostatecnosti. Na toto postizeni je nutne myslet pri vyskytu difuzni myalgie, zvysene svalove citlivosti provazene bolestmi nebo pri zvyseni kreatinfosfokinazy (CPK) svaloveho puvodu na petinasobek normalni hodnoty. Tato situace vyzaduje preruseni lecby.

Riziko svaloveho poskozeni se krome toho zvysuje v pripadech, kdy je pripravek SUPRELIP uzivan spolecne s jinym fibratem nebo v kombinaci s inhibitory HMG-CoA reduktazy (viz 4.5).

U nekterych pacientu byly zaznamenany behem lecby fibraty zvysene hladiny serovych transaminaz. I kdyz u vetsiny pacientu jde o zvyseni prechodne, behem prvniho roku lecby se doporucuje kontrola jejich hladin kazde 3 mesice. Zvyseni hladin ALT a AST nad trojnasobek horni hranice normy je duvodem k preruseni lecby.

Porucha renalnich funkci

Pri poruse renalnich funkci muze byt nutne snizit davku fenofibratu, a to v zavislosti na hodnote kreatininove clearance.

Jelikoz pripravek SUPRELIP obsahuje sacharozu pacienti se vzacnymi dedicnymi problemy s intoleranci fruktozy, malabsorpci glukozy a galaktozy nebo sacharozo-izomaltazove deficienci by tento pripravek nemeli uzivat.

Podobne jako u jinych fibratu, byl i u pacientu uzivajicich fenofibrat popsan vyskyt pankreatitidy. Tento jev se vysvetluje selhanim ucinnosti u pacientu s tezkou hypertriacylglyceridemii primym ucinkem leku nebo sekundarnim efektem zprostredkovanym kamenem nebo tvorenym „piskem“ ve spolecnem zlucovodu.

U hyperlipidemickych pacientu lecenych estrogeny nebo kontraceptivy obsahujicimi estrogeny by melo byt zjisteno, zdali je hyperlipidemie primarni nebo sekundarni povahy (mozne navyseni hladiny lipidu vyvolane oralnimi estrogeny).

4.5 Interakce s jinymi lecivymi pripravky a jine formy interakce

jine fibraty - zvysuji riziko vzniku nezadoucich ucinku jako je rhabdomyolyza a farmakodynamicky pusobi jako antagoniste.

inhibitory HMG-CoA reduktazy - zvysuji riziko vzniku rhabdomyolyzy, zejmena v pripade jiz existujiciho onemocneni svalu. Proto by mela byt kombinovana lecba fenofibratem a statiny vyhrazena pouze pro pacienty s tezkou kombinovanou dyslipidemii a vysokym rizikem vyskytu kardiovaskularni prihody a bez jakehokoli predesleho postizeni svalu. Mozne nezadouci ucinky na svaly museji byt peclive monitorovany.

Kombinace vyzadujici zvlastni pozornost.

peroralni antikoagulancia - zesiluji ucinek antikoagulancii (vytesnenim antikoagulancia z vazebnych mist plazmatickych bilkovin) a zvysuji tak riziko krvaceni. Proto tato kombinace vyzaduje castejsi kontroly Quickova testu.

Pri zahajeni lecby fenofibratem se doporucuje snizit davku peroralniho antikoagulancia o jednu tretinu a v pripade potreby pak jeho davku dale prizpusobit na zaklade hodnot namerenych dle INR. Takto upravena davka se podava jeste 8 dni po ukonceni terapie pripravkem SUPRELIP.

Obecne se nedoporucuje kombinace fenofibratu s peroralnimi antidiabetiky, fenylbutazonem a inhibitory MAO.

Behem soucasneho podavani fenofibratu a cyklosporinu byly zaznamenany zavazne pripady reverzibilniho poskozeni renalnich funkci. Proto musi byt funkce ledvin u techto pacientu peclive monitorovana a v pripade vazne zmeny laboratornich parametru by lecba fenofibratem mela byt ukoncena.

4.6 Fertilita, tehotenstvi a kojeni

Studie na zviratech neprokazaly zadne teratogenni ucinky. Nebyly pozorovany rovnez zadne malformace ani fetotoxicke pusobeni fenofibratu.

Udaje o pusobeni pripravku behem tehotenstvi vsak nejsou dostatecne, a proto je podavani fenofibratu v tehotenstvi kontraindikovano.

Vzhledem k nedostatku udaju o vylucovani fenofibratu do materskeho mleka se nedoporucuje podavat tento pripravek v prubehu kojeni.

4.7 Ucinky na schopnost ridit a obsluhovat stroje

SUPRELIP nema zadny nebo ma zanedbatelny vliv na schopnost ridit nebo obsluhovat stroje.

4.8 Nezadouci ucinky

Nezadouci ucinky jsou serazeny podle cetnosti vyskytu za pouziti nasledujici konvence:

Velmi caste (>1/10);

Caste (> 1/100 az < 1/10)

Mene caste (> 1/1000 az < 1/100)

Vzacne (> 1/10000 az < 1/1000)

Velmi vzacne (< 1/10000)

Neni znamo (z dostupnych udaju nelze urcit)

Nezadouci ucinky nejsou prilis caste, vyskytuji se u 2-4% pacientu a vetsinou nevyzaduji preruseni lecby.

Poruchy svalove a kosterni soustavy a pojivove tkane

Projevuj i se difuzni myalgii, svalovou citlivosti provazenou bolestmi a svalovou slabosti. Po vysazeni leku tyto ucinky vetsinou odezni. Vzacne se muze, stejne jako po podavani jinych fibratu, objevit po podavani pripravku SUPRELIP rhabdomyolyza, ktera si vyzada preruseni lecby (viz bod 4.4).

Vzacne se vyskytly tyto nezadouci ucinky:

- zazivaci potize. zaludecni nebo strevni potize dyspeptickeho razu

- zvysene hladiny transaminaz, vzacne hepatitida (viz bod 4.4)

- kozni alergicke reakce, jako je vyrazka, pruritus, urtika, fotosenzitivita, ktera se muze vyvinout dokonce az po nekolikamesicni bezproblemove lecbe. Projevuje se erytemem, ekzematoidni erupci s papulami nebo puchyrky, ktere se objevuji v mistech vystavenych slunecnimu zareni nebo pusobenim umeleho UV zareni

- alopecie, sexualni astenie a zavrate

- mirne zvyseni seroveho kreatininu a urey a take mirne snizeni hemoglobinu a leukocytu

- byl popsan vyskyt zlucovych kamenu a velmi ojedinele pripady intersticialni pneumonie

Hlaseni podezreni na nezadouci ucinky

Hlaseni podezreni na nezadouci ucinky po registraci leciveho pripravku je dulezite. Umoznuje to pokracovat ve sledovani pomeru prinosu a rizik leciveho pripravku. Zadame zdravotnicke pracovniky, aby hlasili podezreni na nezadouci ucinky na adresu:

Statni ustav pro kontrolu leciv Srobarova 48 100 41 Praha 10

Doposud nebyl zaznamenan zadny pripad predavkovani. Neexistuji specificka antidota a lecba akutniho predavkovani by proto byla symptomaticka.

V pripade nutnosti muze byt proveden vyplach zaludku spolu s dalsi podpurnou peci. Fenofibrat neni mozne odstranit hemodialyzou.

5. FARMAKOLOGICKE VLASTNOSTI

5.1 Farmakodynamicke vlastnosti

Farmakoterapeuticka skupina: Hypolipidemikum/fibrat. ATC kod: C10AB05

Tobolky pripravku SUPRELIP obsahuji 200 mg vysoce biologicky dostupneho mikronizovaneho fenofibratu v jedne tobolce.

Fenofibrat je derivat kyseliny fibrove. Jeho ucinky na upravu hladiny lipidu u cloveka jsou zprostredkovany aktivaci receptoru alfa aktivovaneho peroxisomovym proliferatorem (PPARa). Fenofibrat je schopen snizit hladinu cholesterolu v seru o 20-25% a hladinu triglyceridu o 40-50% a HDL cholesterol zvysit o 10 az 30%.

Podavani fenofibratu vede ke snizeni hladin aterogennich frakci cholesterolu (VLDL a LDL) a ke zvyseni frakce o vysoke hustote (HDL). U pacientu s hypercholesterolemii, u nichz byly hladiny LDL cholesterolu snizeny o 20-35%, vedl celkovy ucinek na cholesterol ke snizeni pomeru celkoveho cholesterolu k HDL cholesterolu a LDL cholesterolu k HDL cholesterolu.

Byl prokazan vztah mezi hypercholesterolemii a aterosklerozou a mezi aterosklerozou a rizikem vzniku onemocneni koronarnich cev. Nizka hladina HDL toto riziko zvysuje. Vysoka hladina triglyceridu je spojena se zvysenym rizikem vaskularnich prihod, ale zavislost nebyla jeste zcela objasnena. Navic triglyceridy mohou ovlivnovat proces aterogeneze a take trombogeneze.

Vysledky studie DAIS (Diabetes Atherosclerosis Intervention Study) ukazaly, ze fenofibrat signifikantne snizuje progresi koronarni aterosklerozy u pacientu s diabetem II. typu. V teto dvojite slepe, randomizovane, placebem kontrolovane studii se 418 pacienty s diabetem II. typu a prumernou dobou lecby 38 mesicu vyustila lecba fenofibratem v signifikantni zpomaleni progrese loziskovych aterosklerotickych lezi o 40% pri koronarografickem hodnoceni. I kdyz studie DAIS nebyla zamerena na sledovani ovlivneni klinickych prihod, ve zkoumane populaci lecba fenofibratem vyustila v 23% snizeni klinickych kardiovaskularnich prihod (statisticky nesignifikantni).

Existuji dukazy, ze lecba fibraty muze snizit vyskyt ischemicke choroby srdce, ale nebylo prokazano snizeni mortality z jakekoli priciny v primarni ani sekundarni prevenci kardiovaskularniho onemocneni.

Lipidova studie ACCORD (Action to Control Cardiovascular Risk in Diabetes) predstavovala randomizovanou placebem kontrolovanou studii s 5518 pacienty s diabetem mellitus typu 2 lecenych krome simvastatinu take fenofibratem. Lecba fenofibratem spolecne se simvastatinem nevykazala zadne vyrazne rozdily ve srovnani s monoterapii simvastatinem v primarnim kombinovanem vysledku u nefatalniho infarktu myokardu, nefatalni mozkove mrtvice a kardiovaskularniho umrti (relativni riziko - hazard ratio [HR] 0,92, 95 % CI 0,79-1,08, p = 0,32; absolutni snizeni rizika: 0,74 %). V predem specifikovane podskupine dyslipidemickych pacientu, kteri byli definovani jako pacienti v nejnizsim tercilu HDL-C (<34 mg/dl nebo 0,88 mmol/l) a v nejvyssim tercilu TG (>204 mg/dl nebo 2,3 mmol/l) u pocatecnich hodnot, vykazala lecba fenofibratem spolecne se simvastatinem relativni snizeni o 31 % ve srovnani s monoterapii simvastatinem v primarnim kombinovanem vysledku (relativni riziko - hazard ratio [HR] 0,69, 95 % CI 0,49-0,97, p = 0,03; absolutni snizeni rizika: 4,95 %). Dalsi analyza predem specifikovane podskupiny identifikovala statisticky vyznamnou interakci u lecby dle pohlavi (p = 0,01), ktera naznacovala mozny lecebny prinos kombinovane lecby u muzu (p=0,037), ale take potencialne vyssi riziko u primarniho vysledku u zen lecenych kombinovanou lecbou ve srovnani s monoterapii simvastatinem (p=0,069). Tato skutecnost nebyla u drive zminene podskupiny pacientu s dyslipidemii pozorovana, ale nebyl zaznamenan ani zadny jasny dukaz prinosu u zen s dyslipidemii lecenych fenofibratem spolecne se simvastatinem, a tak nelze mozny skodlivy ucinek u teto podskupiny vyloucit.

Pri deletrvajici lecbe fenofibratem, ktere je provazeno vyraznym snizenim hladiny seroveho cholesterolu, muze dojit ke zmenseni az uplnemu vymizeni lozisek extravaskularniho ukladani cholesterolu (xanthomata).

Priblizne u 20% hyperlipidemickych pacientu, zejmena ve skupine pacientu s dyslipidemii typu IV, dochazi ke zvyseni plazmaticke hladiny kyseliny mocove. Urikosuricky efekt fenofibratu vedouci ke snizeni hladiny kyseliny mocove priblizne o 25% prinasi temto pacientum dalsi prospech.

Lecba fenofibratem vede ke zvyseni hladiny apoproteinu A a snizeni hladiny apoproteinu B, jejichz pomer je rovnez doporucovan k hodnoceni miry rizika vzniku aterosklerosy.

U fenofibratu byl prokazan u zvirat a nasledne v prubehu klinickych zkousek i u lidi, antiagregacni ucinek na krevni desticky. Projevuje se snizenim shlukovani trombocytu pusobenim ADP, epinefrinu a kyseliny arachidonove.

U pacientu se zvysenymi hladinami fibrinogenu lecenych fenofibratem se ukazalo vyznamne snizeni tohoto parametru, jako u pacientu se zvysenymi hladinami Lp(a). Pri lecbe fenofibratem se snizuji dalsi zanetlive markery, jako je napr. C-reaktivni protein.

Aktivaci PPAR a (Peroxisome Proliferator Activated Receptor typu a) fenofibrat zvysuje lipolyzu a eliminaci castic bohatych na triglyceridy z plazmy aktivaci lipoprotein-lipazy a redukci apoproteinu CIII.

5.2 Farmakokineticke vlastnosti

Hlavnim plazmatickym metabolitem je kyselina fenofibrova. Nezmeneny pripravek v plazme zjisten nebyl. Maximalni plazmaticke koncentrace je dosahovano prumerne 5 hodin po poziti leku. Pri podavani 1 tobolky pripravku SUPRELIP denne se prumerna plazmaticka koncentrace pohybuje kolem 15 ^g/ml a udrzuje se na teto hladine po celou dobu lecby.

Kyselina fenofibrova se vysoce vaze na plazmaticky albumin, kde muze vytesnit z vazby na albumin oralni antikoagulancia a tim potencovat jejich efekt (viz bod 4.5).

Plazmaticky polocas vylucovani kyseliny fenofibrove je asi 20 hodin. Pripravek je vylucovan hlavne moci. Behem 24 hodin se vylouci 70%, a po 6 dnech je prakticky vyloucen zcela.

Fenofibrat je vylucovan hlavne ve forme kyseliny fenofibrove a jejiho glukuronoveho konjugatu.

Farmakokineticke studie provedene po podani jednotlive davky i po kontinualni lecbe prokazaly, ze nedochazi k hromadeni fenofibratu v organizmu.

Kyselinu fenofibrovou nelze odstranit hemodialyzou.

5.3 Predklinicke udaje vztahujici se k bezpecnosti pripravku

Studie chronicke toxicity byly provedeny na potkanech, psech a opicich druhu rhesus. Ve studiich provedenych na potkanech bylo pozorovano zvyseni hodnot jaternich enzymu a hmotnosti jater.

Mutagenni ucinky nebyly prokazany ani v testech in vitro, ani v testech in vivo. Stejne tak studie na mysich, potkanech a kralicich neprokazaly teratogenni ucinky.

Embryotoxicke ucinky byly pozorovany pri davkach pohybujicich se v oblasti toxicity pro matku. Pri vysokych davkach bylo pozorovano prodlouzeni tehotenstvi a problemy pri porodu. Nebyly pozorovany zadne pripady ovlivneni fertility.

6. FARMACEUTICKE UDAJE

6.1 Seznam pomocnych latek

zrneny cukr(sacharoza, kukuricny skrob)

dimetikonova emulze 35%

simetikonova emulze 30%

6.2 Inkompatibility

6.3 Doba pouzitelnosti

6.4 Zvlastni opatreni pro uchovavani

6.5 Druh obalu a obsah baleni

Nitriderm Tts 10mg, Nitriderm

NITRIDERM TTS 10MG/24H

Transcript

You should also ask yourself these questions before using the patch:

Transiderm Nitro® 10 / Nitriderm TTS 10mg/24h (glyceryl trinitrate)

PATIENT INFORMATION LEAFLET

If the answer to any of these questions is YES, tell your doctor or pharmacist because Transiderm Nitro 10 might not be the right medicine for you.

Your medicine is available using the names Transiderm Nitro 10 / Nitriderm TTS 10mg/24h, but will be referred to as Transiderm Nitro 10 in this leaflet. This product is available in other strengths (Transiderm Nitro 5).

Are you taking other medicines?

Transiderm Nitro 10 interacts with a large number of other medicines. Tell your doctor or pharmacist if you are taking any of the following:

What you need to know about Transiderm Nitro 10

Your doctor has decided that you need this medicine to help treat your condition.

Please read this leaflet carefully before you start to use the patches. It contains important information. • •

Keep the leaflet in a safe place because you may want to read it again. If you have any other questions, or if there is something you don’t understand, please ask your doctor or pharmacist. This medicine has been prescribed for you. Never give it to someone else. It may not be the right medicine for them even if their symptoms seem to be the same as yours. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

this leaflet: What Transiderm Nitro 10 is and what it is used for Things to consider before you start to use Transiderm Nitro 10 How to use Transiderm Nitro 10 Possible side effects How to store Transiderm Nitro 10 Further information

WHAT TRANSIDERM NITRO 10 IS AND WHAT IT IS USED FOR

Medicines for depression Ergotamine products which are usually given for migraine Medicines for erectile dysfunction (male impotence) Medicines for high blood pressure or heart problems Aspirin or other painkillers called NSAIDs (non-steroidal anti-inflammatory drugs) Diuretics (“water tablets”) Tranquillisers (e. g. chlorpromazine, flupenthixol, haloperidol, clozapine).

Always tell the doctor or pharmacist about all of the medicines you are taking. This means medicines you have bought yourself, as well as medicines on prescription from the doctor.

Will there be any problems with driving or using machinery?

Some people have reported feeling faint or dizzy when they have started to use the patches. You should not drive or operate machinery if you are affected.

Other special warnings

Be careful when drinking alcohol as the patch may affect you more than usual and you might feel faint or dizzy. You might find that your GTN (glyceryl trinitrate) tablets or spray aren’t working as well as they used to. Discuss this with your doctor. You must tell the doctor or nurse if you are wearing a patch before an MRI scan (Magnetic Resonance Imaging scan to visualise internal organs and tissues of the body) or diathermy treatment (treatment using hot wires) and before electrical treatment on the heart.

Transiderm Nitro 10 is a patch which you stick on your skin. The patch contains a supply of glyceryl trinitrate which is released from the patch and absorbed through the skin and into the blood vessels. This is called a transdermal patch. See diagram of patch below. WATERPROOF BACKING

Have you recently had a heart attack or do you have heart failure or other heart problems? Do you suffer from anaemia or lung disease? Are you pregnant or trying to become pregnant? Are you breast feeding?

HOW TO USE TRANSIDERM NITRO 10

It is important to follow what your doctor says about how and when to use your patches. The dose will be on the pharmacist’s label. Check the label carefully. If you are not sure, ask your doctor or pharmacist.

SPECIAL MEMBRANE WHICH CONTROLS THE RATE OF RELEASE OF GTN

LAYER OF WATER-RESISTANT ADHESIVE

The doctor will tell you how often to change the patch. Discard the old patch carefully because it will still contain a little of the active ingredient.

RESERVOIR OF GLYCERYL TRINITRATE (GTN)

The side of the chest is a suitable place to apply the patch. Choose a different area of skin each time you apply a new patch. Leave several days before you use the same patch of skin again.

How to apply the patch

Decide where you will put the patch. It is important that you put it on a hairless area to ensure that it sticks well. The side of the chest is recommended.

Glyceryl trinitrate, the active ingredient in the patches is one of a group of medicines called vasodilators. These cause blood vessels to relax, increasing the supply of blood and oxygen to the heart and reducing the amount of work the heart has to do. Transiderm Nitro 5 and 10 are used •

Wash the skin and dry it thoroughly to make sure the patch sticks well. Wait a minute until the skin feels quite dry. Do not use powder.

Remove one sachet from the box and tear open the sachet at the notch. Use your fingers as cutting with scissors might damage the patch inside. Remove the patch from the sachet.

to prevent angina attacks. Angina means a painful tightness in the chest. This is a good description of a typical attack, although the pain may also be felt in the arm or neck. The pain really comes from the heart muscle and is a sign that part of the muscle is not getting enough blood supply for the amount of work it has to do.

Transiderm Nitro 5 is also used in patients who are receiving food or drugs directly into a vein (intravenously) • to prevent irritation and the intravenous fluid leaking into the surrounding tissues.

THINGS TO CONSIDER BEFORE YOU START TO USE TRANSIDERM NITRO 10

Some people MUST NOT use Transiderm Nitro 10. Talk to your doctor if: • • • • •

you think you may be allergic to glyceryl trinitrate or other nitrates or to any of the other ingredients of the patch. (These are listed at the end of the leaflet) you have very low blood pressure. you have headaches, vomiting or seizures as a result of raised pressure inside the skull. you have any problems with your heart because of faulty valves or inflammation. you are taking any medicines for erectile dysfunction (male impotence).

If you are hospitalised due to severe dehydration or loss of blood tell the doctor you are using a Transiderm Nitro 10 patch.

Peel off the white plastic backing and discard it. Do not touch the sticky surface of the patch.

HOW TO STORE TRANSIDERM NITRO 10

Do not store your patches above 25?C. Do not open the sealed sachet until you are going to use the patch. Keep out of the sight and reach of children. Do not use these patches after the expiry date which is printed on the carton. If your doctor tells you to stop using Transiderm Nitro 10 patches, please take any which are left to your pharmacist to be destroyed. Only keep them if the doctor tells you to. Do not throw them away with your normal household waste or water. This will help to protect the environment. If your medicine appears to be discoloured or show any other signs of deterioration, please return to your pharmacist who will advise you.

Place the sticky side of the patch on the clean skin, press firmly while you count slowly up to five.

6/7. Run your finger around the edge of the patch to make sure no air or water can get in. If you have applied the patch correctly you can bathe, shower or swim with little risk of the patch coming off.

What Transiderm Nitro 10 Contain Each Transiderm Nitro 10 patch contains 50mg of glyceryl trinitrate as the active ingredient. For each Transiderm Nitro 10, your body will absorb approximately 10mg over 24 hours. This patch is designed to release the drug through your skin into your body at a slow rate. The patches also contain the following inactive ingredients: lactose, silicone oil, polyvinylchloride (PVC). Aerosil 200, Ethylene-vinyl Acetate co-polymer, polyethylene terephthalate, aluminium, vinyl acetate co-polymer, and silicon adhesive.

What Transiderm Nitro 10 looks like and contents of the pack To prevent angina The usual dosage for adults and the elderly is one or two patches applied daily. The doctor will have decided which strength of patch you need.

Transiderm Nitro 10 are self adhesive pink coloured patches containing a drug reservoir.

You may be told to wear a patch all of the time or for only part of the day. Don’t forget to follow the doctor’s instructions exactly.

Transiderm Nitro 10 comes in packs containing 30 patches.

Manufactured by: Famar France, 1, Avenue du Champ de Mars, 45072 Orleans, Cedex, France. Or Novartis Pharma S. A.S. 26 rue de la Chapelle, 68330 Huningue, France. Or Novartis Pharma S. A.S. 2 et 4, rue Lionel Terray, 92500 Rueil-Malmaison, France.

Do not stop using the patches suddenly without consulting your doctor first. Sometimes patches are not enough to prevent all of your angina attacks and you may be given tablets as well. Make sure you know when you need to take the tablets.

Procured from within the EU and repackaged by: Doncaster Pharmaceuticals Group Ltd. Kirk Sandall, Doncaster, DN3 1QR.

To prevent skin irritation when you are receiving drugs intravenously (into a vein) One Transiderm Nitro 5 patch will be applied when the treatment is started and the patch changed every 3–4 days until the treatment is stopped.

Product Licence holder: BR Lewis Pharmaceuticals Ltd. Kirk Sandall, Doncaster, DN3 1QR.

Transiderm Nitro 10 is not suitable for children.

PL No: 08929/0156

What if you forget to change your patch?

Leaflet revision and issue date: 23.01.15

If you forget to change your patch, do not worry. Put on a new one as soon as you remember. Then go on as before.

Transiderm Nitro® is a registered trademark of Novartis AG.

What if you accidentally use too many patches?

To listen to or request a copy of this leaflet in Braille, large print or audio please call 01302 552940 and ask for the Regulatory Department.

If you accidentally apply too many Transiderm Nitro 10 patches, tell your doctor or nearest hospital casualty department immediately. Take your medicine pack with you.

POSSIBLE SIDE EFFECTS

Transiderm Nitro 10 patches are suitable for most people. However, like all medicines they can sometimes cause side effects.

The side effects listed below have been reported: More than 10% of people have experienced ?

Nausea (feeling sick) or vomiting (being sick).

Up to 1 in 10 people have experienced: ?

Headaches. These will probably wear off after a few days. If necessary you can take mild painkillers e. g. paracetamol.

Up to 1 in 100 people have experienced: ? ?

Reddening, itching or burning of the skin at the site of the patch. Be sure to put your patch in a different place each day. Allergic skin reactions such as reddening or itching anywhere on the body.

Up to 1 in 1,000 people have experienced: ? ? ?

Increased heart rate or palpitations. Feeling faint or light-headed on standing, or feeling dizzy. Flushing of the face.

If any of the symptoms become troublesome, or if you notice anything else not mentioned here, please go and see your doctor. He/she may want to reduce the dose or give you a different medicine.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via: Yellow Card Scheme Website: www. mhra. gov. uk/yellowcard By reporting side effects, you can help provide more information on the safety of this medicine.

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Spironolactone (Aldactone) - Side Effects, Dosage, Interactions, Novospiroton

Spironolactone (Aldactone)

Spironolactone is the generic form of the brand-name drug Aldactone. a prescription diuretic drug.

The drug is used to treat a condition called primary hyperaldosteronism, in which the body produces excess amounts of the hormone aldosterone, which regulates your body’s sodium and water levels.

Spironolactone helps restore a healthy balance of sodium and potassium in your body.

It’s also used to treat:

Essential hypertension (high blood pressure with an unknown cause)

Hypokalemia (potassium deficiency)

Edema (fluid retention) from various conditions, including congestive heart failure, kidney disease, and cirrhosis (liver scarring)

Severe heart failure

Spironolactone is a potassium-sparing diuretic. Sometimes called "water pills," diuretics help the kidneys expel water and salt in urine while retaining potassium.

The drug may also be used in combination with other medications to treat precocious (early) puberty and myasthenia gravis. a neuromuscular disease.

Manufactured by Pfizer, s pironolactone was approved by the Food and Drug Administration (FDA) in 1985.

Though s pironolactone has been around for over 25 years, the FDA is still updating the drug's safety labeling.

In 2011, the FDA added Stevens-Johnson syndrome and toxic epidermal necrolysis — two life-threatening skin disorders — to s pironolactone 's list of possible side effects.

In 2013, the agency added a warning about a potentially fatal condition called hyperkalemia (high potassium levels in the blood).

Spironolactone for Acne

Spironolactone is sometimes used off-label to treat women with persistent adult acne due to increased androgen levels, because the drug is able to inhibit the activity of sebaceous glands (small skin glands that releases an oily, lubricating substance called sebum).

The development of acne lesions is associated partly with increased sebum secretion, which can be stimulated in women by androgen excess.

Spironolactone for Hair Loss and Hirsutism

Because of its anti-androgen activity, s pironolactone is also used off-label to treat female-pattern hair loss and hirsutism.

Women with certain endocrine disorders produce more androgens than normal, leading to hair loss on the top or front of the scalp, and increased hair on the face and other (generally hair-free) body areas.

Spironolactone helps by slowing down the production, and blocking the action, of androgens.

Spironolactone Warnings

Spironolactone carries a black-box warning for tumor risk, due to chronic toxicity studies that show spironolactone can cause tumor development in rats.

Spironolactone shouldn't be taken with potassium-supplementing drugs or diets because the excessive potassium intake may cause hyperkalemia, which can lead to abnormal heart rhythms (arrhythmias).

Your doctor should also know if you have severe heart failure, because hyperkalemia has an increased risk of death in such cases.

Additionally, tell your doctor if you have liver problems such as cirrhosis, as even minor changes in fluid and electrolyte balance may cause liver-related coma.

Spironolactone shouldn't be used if you have certain kidney problems or conditions associated with hyperkalemia, including the adrenal gland disorder known as Addison's disease.

Pregnancy and Spironolactone

Spironolactone may pose risks to a developing fetus.

Some research suggests that s pironolactone has the potential to feminize male fetuses during early pregnancy and cause endocrine problems in late pregnancy by inhibiting the activity of male hormones (androgens).

In general, diuretics such as s pironolactone aren't recommended for pregnant women.

Unless the drug is absolutely necessary, it's not recommended for women who are breastfeeding because canrenone, a byproduct of s pironolactone. is excreted in breast milk.

Always tell your doctor about any legal and illegal drugs, supplements, and herbal remedies you are taking.

Spironolactone can have a negative interaction with the following drugs:

Lithium (Eskalith, Lithobid)

ACE inhibitors, such as benazepril (Lotensin)

Angiotensin II receptor blockers, such as azilsartan (Edarbi)

Digoxin (Lanoxin)

Cholestyramine (Questran, Cholybar)

Steroids such as prednisone

Ibuprofin (Advil) and other non-steroidal anti-inflammatory drugs

Inspra (Eplerenone) and other aldosterone receptor antagonists

Heparin (Hemochron, Hep-Lock) and low-molecular-weight heparin (Lovenox)

Skeletal muscle relaxers, including cyclobenzaprine (Amrix, Flexeril)

Other diuretics, such as amiloride (Midamor)

Norepinephrine

Potassium supplements

Spironolactone and Alcohol

While taking Spironolactone, consumption of alcohol, narcotics, or barbiturates (a sedative) can cause dizziness, lightheadedness, or fainting when you get up too quickly from a sitting or lying position.

Therefore, it may be best to avoid drinking alcohol when taking spironolactone.

Spironolactone Dosage

Spironolactone comes as 25 milligrams (mg), 50 mg, and 100 mg oral tablets.

Dosage depends on your health issue:

Primary hyperaldosteronism: 100 to 400 mg daily

Edema: 25 to 200 milligrams every day, for at least 5 days

Essential hypertension: 50 to 100 mg every day, for at least two weeks

Hypokalemia: 25 to 100 mg once daily

Severe heart failure: 25 mg once daily, which may be increased to 50 mg once daily or decreased to 25 mg once every other day, depending on your tolerance of the drug

Spironolactone Overdose

Overdosing on spironolactone can result in:

Drowsiness, dizziness, or confusion

Rash

Nausea, vomiting, or diarrhea

Loss of muscle tone, weakness, or heaviness in the legs

Tingling in the arms and legs

Arrhythmia

Call your local poison control center if you've overdosed on spironolactone. If someone has collapsed or is not breathing from a spironolactone overdose, call 911.

Missed Dose of Spironolactone

Take your missed dose of s pironolactone as soon as you remember it.

Skip your missed dose if it's almost time for your next dose.

Don’t "double-dose" to make up for a missed dose.

Cryselle, Lo, Cryselle

norgestrel/ethinylestradiol (Rx) Brand and Other Names: Cryselle, Lo/Ovral, more. Lo/Ovral-28, LoFemanal, Low-Ogestrel, Elinest, Ogestrel

Black Box Warnings

cigarette smoking & risk of cardiovascular disease

Cigarette smoking increases risk of serious cardiovascular adverse effects from combination hormonal contraceptive use

This risk increases with age (>35 yr) and with heavy smoking (15 or more cigarettes/day)

Advise women who use hormonal oral contraceptives not to smoke

Contraindications

Active or history of breast cancer

Arterial thromboembolic disease (stroke, MI), thrombophlebitis, DVT/PE, thrombogenic valvular disease

Liver disease, liver tumors

Undiagnosed abnormal vaginal bleeding

Diabetes mellitus with vascular involvement, jaundice with prior oral contraceptive use

Cautions

Family history of breast cancer and or DVT/PE, current/history of depression, endometriosis, DM, HTN, bone mineral density changes, renal/hepatic impairment, bone metabolic disease, SLE; conditions exacerbated by fluid retention (eg, migraine, asthma, epilepsy)

Discontinue if the following develop jaundice, visual problems (may cause contact lens intolerance), any signs of VTE, migraine with unusual severity, significang blood pressure increase, severe depression, increased risk of thromboembolic complications after surgery

Discontinue 4 week before major surgery or prolonged immobilization. Patients on warfarin, oral anticoagulants (increase in anticoagulant dose may be warranted)

Some studies link OCP use with increased risk of breast cancer, whereas other studies have not shown a change in risk; woman's risk depends on conditions where naturally high hormone levels persist for long periods of time including early onset menstruation before age 12, late onset menopause, after age 55, first child after age 30, nulliparity

Increased risk of cervical cancer with OCP use, however HPV remains as main risk factor for this cancer; evidence suggests long-term use of OCPs, 5 or more years, may be associated with increased risk

Increased risk of liver cancer with OCP use; risk increases with longer duration of OCP use

CDC guidelines recommend waiting at least 3 weeks following vaginal birth or 6 weeks after cesarean section to decrease risk for venous thromboembolism before initiating combined hormonal contraceptives; women with additional risk factors for VTE (besides postpartum) should not use combined hormonal contraceptives (MMWR July 7, 2011)

Pregnancy & Lactation

Pregnancy Category: X

Lactation: small amounts of steroids are excreted in breast milk; estrogens may reduce quality/quantity of milk; may be prudent to use other forms of birth control until full weaning (AAP Committee states compatible with nursing)

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology

Mechanism of Action

Ethinylestradiol (EE): Reduces LHRH release from hypothalamus, reduces gonadotropin release from pituitary; increase synthesis of DNA, RNA, and various proteins in target tissues

Norgestrel: Progestin; inhibits gonadotropin secretion from pituitary; prevents follicular maturation and ovulation, stimulates growth of mammary tissues

Pharmacokinetics

Half-Life: 28 hr (ethinyl estradiol)

Protein Bound: Extensively bound to serum albumin (ethinyl estradiol)

Metabolism: Hepatic CYP3A4 to estriol, estrone (ethinyl estradiol)

Excretion: Ethinyl estradiol: Urine as conjugates, most estrogens are also excreted in bile and undergo enterohepatic recycling

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

View the formulary and any restrictions for each plan.

Manage and view all your plans together – even plans in different states.

Compare formulary status to other drugs in the same class.

Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

This drug is available at the lowest co-pay. Most commonly, these are generic drugs.

This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.

This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.

This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.

This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.

This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.

NOT COVERED – Drugs that are not covered by the plan.

Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.

Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.

Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.

Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Buy Other - Servizid (Brand Name Isoniazid) Online - Order - Purchase Other - Servizid (Brand Name I

Isoniazid is used for treating or preventing tuberculosis (TB). If you are using Isoniazid to treat TB, it should always be used along with another medicine. Isoniazid is an antibacterial. It works by killing TB organisms. soniazid also has an antidepressant effect, and it was one of the first antidepressants discovered. Isoniazid can also be used in the treatment of a BCG-oma.

Use Isoniazid as directed by your doctor.

Take each dose with a full glass (8 ounces) of water.

Take Isoniazid on an empty stomach 1 hour before or 2 hours after meals. If nausea occurs, ask your doctor if you can take Isoniazid with food.

Take all of the Isoniazid that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

It is important to take Isoniazid regularly to get the most benefit.

Your doctor may also want you to take a supplemental vitamin B6 (pyridoxine) tablet daily during treatment to prevent numbness and tingling caused by low levels of this vitamin.

Your doctor may want you to have blood tests or other medical evaluations during treatment with Servizid to monitor progress and side effects.

Continue to use Isoniazid even if you feel well. Do not miss any dose.

If you miss a dose of Isoniazid, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Isoniazid.

Store Isoniazid between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Isoniazid out of the reach of children and away from pets.

Do NOT use Isoniazid if:

you are allergic to any ingredient in Isoniazid or have had severe side effects from isoniazid, such as drug fever, chills, or arthritis

you have severe liver damage, active liver disease, or liver damage from previous use of Isoniazid

you have a history of hepatitis caused by any medicine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Isoniazid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have diabetes, kidney problems, nerve problems (eg, neuropathy) or risk of nerve problems, HIV, or a history of liver problems

if you have a history of alcohol or other substance abuse, have unsanitary injectable drug habits, or drink alcohol daily

if you are older than 35 years old, you have recently given birth, or you have previously taken Isoniazid.

Some medicines may interact with Isoniazid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Acetaminophen, anticoagulants (eg, warfarin), carbamazepine, hydantoins (eg, phenytoin), rifampin, theophylline, or valproic acid because the risk of their side effects may be increased by Isoniazid

Ketoconazole because its effectiveness may be decreased by Isoniazid.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Isoniazid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Check with your doctor before drinking alcohol while using Isoniazid. Alcohol may increase the risk of liver problems. If you have a history of alcohol abuse, you may also be at increased risk of developing nerve problems from Isoniazid. Notify your doctor if you notice any unusual tingling or numbness in your hands or feet.

If you have a history of diabetes, alcohol abuse, or poor nutrition, your doctor may recommend that you also take vitamin B 6 while you are taking Isoniazid. This may help to decrease your risk of nerve problems. Discuss any questions with your doctor.

Do not eat foods high in tyramine while you use Isoniazid. Eating foods high in tyramine (eg, aged cheeses, red wines, beer, certain meats and sausages, liver, sour cream, soy sauce, raisins, bananas, avocados) while you use Isoniazid may cause severe high blood pressure. Seek medical attention at once if symptoms of severe high blood pressure occur. These may include severe headache, fast or irregular heartbeat, sore or stiff neck, nausea, vomiting, sweating, enlarged pupils, or sensitivity to light.

Do not eat foods high in histamine while you use Isoniazid. Eating foods high in histamine (eg, skipjack, tuna, tropical fish) while you use Isoniazid may cause low blood pressure, irregular heartbeat, headache, sweating, or flushing. Contact your doctor at once if any of these symptoms occur.

Ask your health care provider for a complete list of all foods you should avoid while you are using Isoniazid.

Isoniazid only works against TB bacteria; it does not treat viral infections (eg, the common cold).

Be sure to use Isoniazid for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Diabetes patients - Isoniazid may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine. You may also be at increased risk of developing nerve problems from Isoniazid. Contact your doctor if you notice any unusual tingling in your hands or feet.

Lab tests, including liver function and eye exams, may be performed while you use Isoniazid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Isoniazid with caution in black and Hispanic women; they may have a greater risk of severe liver problems from Isoniazid.

Use Isoniazid with caution in patients older 35 years; they may have a greater risk of severe liver problems from Isoniazid.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Isoniazid while you are pregnant. Isoniazid is found in breast milk. If you are or will be breast-feeding while you use Isoniazid, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Mild stomach upset.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; chills or fever; dark urine; general feeling of discomfort; increased thirst or urination; joint pain or swelling; loss of appetite; memory problems; mental or mood changes; nausea; seizures; stomach pain or tenderness; symptoms of low vitamin B 6 levels (eg, confusion, cracks in the corners of the mouth, irritability, mouth redness or soreness, scaly rash); tingling or numbness in the hands or feet; unusual bruising or bleeding; unusual tiredness or weakness; vomiting; yellowing of the skin or eyes. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Atorvastatin Side Effects In Detail, Vastatin

Atorvastatin Side Effects

In Summary

Commonly reported side effects of atorvastatin include: diarrhea, arthralgia, and nasopharyngitis. Other side effects include: urinary tract infection, insomnia, myalgia, musculoskeletal pain, nausea, muscle spasm, and limb pain. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to atorvastatin: oral tablet

In addition to its needed effects, some unwanted effects may be caused by atorvastatin. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking atorvastatin:

Less common or rare:

Cough

difficulty with swallowing

dizziness

fast heartbeat

fever

hives

itching

muscle cramps, pain, stiffness, swelling, or weakness

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

skin rash

tightness in the chest

unusual tiredness or weakness

wheezing

Incidence not known:

Blistering, peeling, or loosening of the skin

chills

dark-colored urine

diarrhea

joint pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

red skin lesions, often with a purple center sore

red, irritated eyes

sore throat

sores, ulcers, or white spots in the mouth or on the lips

Minor Side Effects

Some of the side effects that can occur with atorvastatin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

Headache

hoarseness

lower back or side pain

pain or tenderness around the eyes and cheekbones

painful or difficult urination

stuffy or runny nose

Less common:

Abdominal or stomach pain

back pain

belching or excessive gas

constipation

general feeling of discomfort or illness

heartburn, indigestion, or stomach discomfort

lack or loss of strength

loss of appetite

nausea

shivering

sweating

trouble sleeping

vomiting

Incidence not known:

Appetite increased

black, tarry stools

bloody nose

bloody or cloudy urine

blurred vision

continuing ringing or buzzing or other unexplained noise in the ears

difficult, burning, or painful urination

difficulty seeing at night

excessive muscle tone or tension

fruit-like breath odor

groin or scrotum pain

inability to have or keep an erection

increased body movements

increased sensitivity of the eyes to light

increased sensitivity to touch or pain

increased thirst

increased urination

loss of bladder control

loss of sexual ability, drive, or desire

menstrual bleeding occurring earlier or lasting longer than usual

mental depression

nervousness

nightmares

pale skin

paranoia

pinpoint red spots on the skin

slurred speech

swollen or tender lymph glands in the neck, armpit, or groin

unable to move or feel face

unusual bleeding or bruising

weight loss

For Healthcare Professionals

Applies to atorvastatin: oral tablet

General

The most frequently reported side effects were nasopharyngitis, arthralgia, diarrhea, pain in extremity, and urinary tract infection. [Ref ]

Gastrointestinal

Very common (10% or more): Diarrhea (up to 14.1%) Common (1% to 10%): Dyspepsia, nausea, flatulence, constipation Uncommon (0.1% to 1%): Abdominal discomfort, eructation, abdominal pain, vomiting, pancreatitis [Ref ]

Hepatic

Common (1% to 10%): Blood bilirubin increased, ALT increased, transaminases/hepatic enzymes increased, AST increased, liver function test abnormal, blood alkaline phosphatase increased Uncommon (0.1% to 1%): Hepatitis Rare (0.01% to 0.1%): Cholestasis Very rare (less than 0.1%): Fatal hepatic failure, nonfatal hepatic failure [Ref ]

Musculoskeletal

Very common (10% or more): Arthralgia (up to 11.7%) Common (1% to 10%): Pain in extremity, musculoskeletal pain, muscle spasms, myalgia, joint swelling, back pain, creatine phosphokinase increased Uncommon (0.1% to 1%): Neck pain, muscle fatigue Rare (less than 0.1%): Myositis, myopathy, rhabdomyolysis, tendinopathy Frequency not reported: Immune-mediated necrotizing myopathy Postmarketing reports: Tendon rupture [Ref ]

Hematologic

Rare (less than 0.1%): Thrombocytopenia [Ref ]

Nervous system

Common (1% to 10%): Headache Uncommon (0.1% to 1%): Paresthesia, dizziness, hypoesthesia, dysgeusia, amnesia Rare (less than 0.1%): Peripheral neuropathy Frequency not reported: Nonfatal hemorrhagic stroke Postmarketing reports: Cognitive impairment, memory loss, forgetfulness, memory impairment [Ref ]

Endocrine

Very rare (less than 0.01%): Gynecomastia [Ref ]

Hypersensitivity

Common (1% to 10%): Allergic reactions Rare (less than 0.1%): Anaphylaxis, hypersensitivity reaction [Ref ]

Psychiatric

Common (1% to 10%): Insomnia Uncommon (0.1% to 1%): Nightmare Postmarketing reports: Confusion, depression [Ref ]

Genitourinary

Common (1% to 10%): Urinary tract infection Uncommon (0.1% to 1%): White blood cells urine positive, erectile dysfunction [Ref ]

Dermatologic

Uncommon (0.1% to 1%): Rash, pruritus, urticaria, alopecia Rare (less than 0.1%): Angioneurotic edema/angioedema, bullous rashes, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis Frequency not reported: Urticaria [Ref ]

Cardiovascular

Common (1% to 10%): Cardiovascular death [Ref ]

Respiratory

Very common (10% or more): Nasopharyngitis (up to 12.9%) Common (1% to 10%): Pharyngolaryngeal pain, epistaxis Uncommon (0.1% to 1%): Asthma Rare (less than 0.1%): Sinusitis, pharyngitis Frequency not reported: Interstitial lung disease [Ref ]

Ocular

Uncommon (0.1% to 1%): Vision blurred Rare (less than 0.1%): Visual disturbance [Ref ]

Other

Common (1% to 10%): Non-cardiovascular death Uncommon (0.1% to 1%): Deafness, tinnitus, malaise, asthenia, influenza, infection, chest pain, peripheral edema, fatigue, pyrexia Rare (0.01% to 0.1%): Injury Very rare (less than 0.01%): Hearing loss [Ref ]

Metabolic

Common (1% to 10%): Hyperglycemia Uncommon (0.1% to 1%): Anorexia, hypoglycemia, weight increased Frequency not reported: Diabetes mellitus [Ref ]

References

1. "Product Information. Lipitor (atorvastatin)." Parke-Davis, Morris Plains, NJ.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Not all side effects for atorvastatin may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here .

Phenazopyridine Side Effects In Detail, Phenazopyridin

Phenazopyridine Side Effects

For the Consumer

Applies to phenazopyridine: oral kit, oral tablet

As well as its needed effects, phenazopyridine may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking phenazopyridine, check with your doctor or nurse as soon as possible:

Rare

Blue or blue-purple color of skin

fever and confusion

shortness of breath, tightness in chest, wheezing, or troubled breathing

skin rash

sudden decrease in the amount of urine

swelling of face, fingers, feet, and/or lower legs

unusual tiredness or weakness

weight gain

yellow eyes or skin

Minor Side Effects

Some phenazopyridine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common or rare:

Dizziness

headache

indigestion

itching of the skin

stomach cramps or pain

For Healthcare Professionals

Applies to phenazopyridine: compounding powder, oral tablet

Nervous system

Nervous system side effects have included headache. [Ref ]

Dermatologic

Dermatologic side effects have included rash and pruritus. [Ref ]

Gastrointestinal

Gastrointestinal side effects have included occasional upset. [Ref ]

Genitourinary

Genitourinary side effects have included an orange to red discoloration of the urine. [Ref ]

References

1. "Product Information. Pyridium (phenazopyridine)." Warner Chilcott Laboratories, Rockaway, NJ.

It is possible that some side effects of phenazopyridine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

More about phenazopyridine

Consumer resources

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill. knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs. com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Drug Status

Buy Fenacop Retard - Diclofenac - Online Without Prescriptions, Fenacop Retard

Diclofenac (Fenacop retard)

Diclofenac is used primarily for the treatment of inflammation and pain caused by conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also effective in treating soft tissue inflammations due to tendinitis and bursitis, and treating dysmenorrhea (menstrual cramps). Diclofenac is an NSAID. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Use Diclofenac as directed by your doctor!

Take Diclofenac by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.

Take Diclofenac with a full glass of water (8 oz/240 mL) as directed by your doctor.

If you miss a dose of Diclofenac, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Diclofenac.

Store Diclofenac at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diclofenac out of the reach of children and away from pets.

Do NOT use Diclofenac if:

you are allergic to any ingredient in Diclofenac or to bovine (cow) protein

you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)

you have recently had or will be having bypass heart surgery

you have severe kidney problems

you are in the last 3 months of pregnancy.

Contact your doctor or health care provider right away if this applies to you.

Some medical conditions may interact with Diclofenac. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have a history of kidney or liver problems, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers)

if you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation

if you have high blood pressure, blood disorders (eg, porphyria), bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases

if you have poor health, dehydration or low fluid volume, or low blood sodium levels, you smoke, drink alcohol, or have a history of alcohol abuse

if you are taking an antibiotic or an anti-seizure medicine. The risk of liver problems may be increased with some of these medicines.

Some medicines may interact with Diclofenac. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin), aspirin, clopidogrel, corticosteroids (eg, prednisone), heparin and other blood thinners (eg, dalteparin), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased

Acetaminophen because the risk of liver problems may be increased

Probenecid because it may increase the risk of Diclofenac's side effects

Cyclosporine, lithium, metformin, methotrexate, oral NSAIDs (eg, ibuprofen), or quinolones (eg, ciprofloxacin) because the risk of their side effects may be increased by Diclofenac

Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Diclofenac.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Diclofenac may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Diclofenac may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Diclofenac with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.

Serious stomach ulcers or bleeding can occur with the use of Diclofenac. Taking it in high doses, for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Diclofenac with food will NOT reduce the risk of these effects. If you have severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling, contact your doctor or emergency room right away.

Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

Diclofenac is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID (eg, ibuprofen) in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Do not take aspirin while you are using Diclofenac unless your doctor tells you to.

Check with your doctor or pharmacist before you take acetaminophen while you are taking Diclofenac. The risk of liver problems may be increased.

Do not switch between different forms of Diclofenac (eg, enteric-coated tablets, immediate-release tablets, capsules) unless your doctor tells you to. They may not provide the same amount of medicine to your body.

Lab tests, including kidney function, liver function, blood electrolyte levels, complete blood cell counts, and blood pressure, may be performed while you use Diclofenac. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Diclofenac with caution in the elderly; they may be more sensitive to its effects, especially stomach bleeding and kidney problems.

Diclofenac should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.

Pregnancy and breast-feeding: Diclofenac may cause harm to the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Diclofenac while you are pregnant. It is not known if Diclofenac is found in breast milk. Do not breastfeed while taking Diclofenac.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; headache; mild stomach pain or heartburn; nausea; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; persistent flu-like symptoms; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting or diarrhea; shortness of breath; sudden or unexplained weight gain; swelling of the hands, legs, or feet; symptoms of liver problems (eg, dark urine, pale stools, persistent loss of appetite, yellowing of the skin or eyes); unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Product Description Common use Ampicillin is a broad-spectrum antibiotic from aminopenicillin group. Its mechanism of action is anti-bacterial and consists in inhibition of construction of bacteria cell walls sensitive to Ampicillin. It is not destroyed in acidic content of stomach, it is easily absorbed. Ampicillin is active toward gram positive microorganisms and also some gram negative ones (salmonella, schigella, proteus, E. coli, Klebsiella pneumoniae, Haemophilus influenzae, formerly called Pfeiffer's bacillus) and is used for treatment of the diseases provoked by mixed bacteria. Microorganisms producing penicillase are resistible to Ampicillin. This medication is used to treat pneumonia and other infectious diseases of respiratory, urogenital, gastrointestinal systems.

Dosage and directions Take exactly as prescribed. ampicillin capsules should be taken with a full glass of water, a half hour before or 2 hours after a meal.

Precautions If you are allergic to penicillin or cephalosporin antibiotics, contact your doctor before taking this drug. This medication may cause diarrhea so inform your doctor if you have it before taking any drug for diarrhea. Ampicillin may show a false positive result of in certain urine glucose tests. If you have taken Ampicillin for a long time before it may appear ineffective in your organism due to so called superinfection, inform your doctor if your symptoms do not improve or get worse.

Contraindications Hypersensitivity to Ampicillin. Cautiousness should be exercised if there is liver failure, asthma, hay fever.

Possible side effect Colitis, diarrhea, fever, itching, nausea, rash, sore tongue or mouth, vomiting.

Drug interaction Ampicillin enhances effect of the orally taken medications which prevent blood clot formation. This medication may interfere with the work of certain oral contraceptives.

Missed dose Never take a double dose of this medication. If you take this medication twice daily and you have missed a dose, take it as soon as you remember, take the next dose 5-6 hours later. If you take the drug thrice daily, take the missed dose as soon as you remember and do the next one in 2-4 hours.

Overdose If you suppose that you took too much Ampicillin and have symptoms of allergy (hives, rush) contact your doctor immediately.

Storage Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care advisor or doctor in charge of the case. We disclaim all responsibility for the reliability of this information. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Product Description Common use Ampicillin is a broad-spectrum antibiotic from aminopenicillin group. Its mechanism of action is anti-bacterial and consists in inhibition of construction of bacteria cell walls sensitive to Ampicillin. It is not destroyed in acidic content of stomach, it is easily absorbed. Ampicillin is active toward gram positive microorganisms and also some gram negative ones (salmonella, schigella, proteus, E. coli, Klebsiella pneumoniae, Haemophilus influenzae, formerly called Pfeiffer's bacillus) and is used for treatment of the diseases provoked by mixed bacteria. Microorganisms producing penicillase are resistible to Ampicillin. This medication is used to treat pneumonia and other infectious diseases of respiratory, urogenital, gastrointestinal systems.

Dosage and directions Take exactly as prescribed. ampicillin capsules should be taken with a full glass of water, a half hour before or 2 hours after a meal.

Precautions If you are allergic to penicillin or cephalosporin antibiotics, contact your doctor before taking this drug. This medication may cause diarrhea so inform your doctor if you have it before taking any drug for diarrhea. Ampicillin may show a false positive result of in certain urine glucose tests. If you have taken Ampicillin for a long time before it may appear ineffective in your organism due to so called superinfection, inform your doctor if your symptoms do not improve or get worse.

Contraindications Hypersensitivity to Ampicillin. Cautiousness should be exercised if there is liver failure, asthma, hay fever.

Possible side effect Colitis, diarrhea, fever, itching, nausea, rash, sore tongue or mouth, vomiting.

Drug interaction Ampicillin enhances effect of the orally taken medications which prevent blood clot formation. This medication may interfere with the work of certain oral contraceptives.

Missed dose Never take a double dose of this medication. If you take this medication twice daily and you have missed a dose, take it as soon as you remember, take the next dose 5-6 hours later. If you take the drug thrice daily, take the missed dose as soon as you remember and do the next one in 2-4 hours.

Overdose If you suppose that you took too much Ampicillin and have symptoms of allergy (hives, rush) contact your doctor immediately.

Storage Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care advisor or doctor in charge of the case. We disclaim all responsibility for the reliability of this information. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Product Description Common use Ampicillin is a broad-spectrum antibiotic from aminopenicillin group. Its mechanism of action is anti-bacterial and consists in inhibition of construction of bacteria cell walls sensitive to Ampicillin. It is not destroyed in acidic content of stomach, it is easily absorbed. Ampicillin is active toward gram positive microorganisms and also some gram negative ones (salmonella, schigella, proteus, E. coli, Klebsiella pneumoniae, Haemophilus influenzae, formerly called Pfeiffer's bacillus) and is used for treatment of the diseases provoked by mixed bacteria. Microorganisms producing penicillase are resistible to Ampicillin. This medication is used to treat pneumonia and other infectious diseases of respiratory, urogenital, gastrointestinal systems.

Dosage and directions Take exactly as prescribed. ampicillin capsules should be taken with a full glass of water, a half hour before or 2 hours after a meal.

Precautions If you are allergic to penicillin or cephalosporin antibiotics, contact your doctor before taking this drug. This medication may cause diarrhea so inform your doctor if you have it before taking any drug for diarrhea. Ampicillin may show a false positive result of in certain urine glucose tests. If you have taken Ampicillin for a long time before it may appear ineffective in your organism due to so called superinfection, inform your doctor if your symptoms do not improve or get worse.

Contraindications Hypersensitivity to Ampicillin. Cautiousness should be exercised if there is liver failure, asthma, hay fever.

Possible side effect Colitis, diarrhea, fever, itching, nausea, rash, sore tongue or mouth, vomiting.

Drug interaction Ampicillin enhances effect of the orally taken medications which prevent blood clot formation. This medication may interfere with the work of certain oral contraceptives.

Missed dose Never take a double dose of this medication. If you take this medication twice daily and you have missed a dose, take it as soon as you remember, take the next dose 5-6 hours later. If you take the drug thrice daily, take the missed dose as soon as you remember and do the next one in 2-4 hours.

Overdose If you suppose that you took too much Ampicillin and have symptoms of allergy (hives, rush) contact your doctor immediately.

Storage Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care advisor or doctor in charge of the case. We disclaim all responsibility for the reliability of this information. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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