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Daniel Almirall, Ph, Almiral

Daniel Almirall

Research Interests

Methodological Interests . My current methodological research interests lie in the broad area of causal inference. I am particularly interested in methods for causal inference using longitudinal data sets in which treatments, covariates, and outcomes are all time-varying. I am also interested in developing statistical methods that can be used to form adaptive interventions, sometimes known as dynamic treatment regimes. An adaptive intervention is a sequence of individually tailored decisions rules that specify whether, how, and when to alter the intensity, type, or delivery of treatment at critical decision points in the medical care process. Adaptive interventions are particularly well-suited for the management of chronic diseases, but can be used in any clinical setting in which sequential medical decision making is essential for the welfare of the patient. They hold the promise of enhancing clinical practice by flexibly tailoring treatments to patients when they need it most, and in the most appropriate dose, thereby improving the efficacy and effectiveness of treatment.

Study Design Interests . In addition to developing new statistical methodologies, I devote a portion of my research to the design of sequential multiple assignment randomized trials (SMARTs). SMARTs are randomized trial designs that give rise to high-quality data that can be used to develop and optimize adaptive interventions.

Substantive Interests . As an investigator and methodologist in the Institute for Social Research, I take part in research in a wide variety of areas of social science and treatment (or interventions) research. I am particularly interested in the substantive areas of mental health (depression, anxiety) and substance abuse, especially as related to children and adolescents.

Key words . causal inference, propensity score methods, marginal and structural nested mean models, methods for longitudinal data analysis, health services research, mental health, substance abuse, obesity, dynamic treatment regimes, adaptive treatment strategies, sequential multiple assignment randomized trials, adaptive implementation interventions

This includes talks or workshops on Adaptive Intervention Designs or SMART Research Designs:

September 9, 2016. Training on Optimization of Behavioral and Biobehavioral Interventions, Washington DC

Workshop for NIH Program Officials, joint with Linda Collins

October 7, 2016. Institute for Translational Research in Children's Mental Health, Annual Symposium, University of Minnesota, Twin Cities, MN

Invited Talk

December 6, 2016. Department of Biostatistics, Johns Hopkins University, Baltimore, MD

Invited Talk

January 26, 2017. Center for Causal Inference, RAND Corporation, Santa Monica, CA

Invited Talk

Journal Articles

Submitted

NeCamp, T. Kilbourne, A. Almirall D. (senior author) (under review). Cluster-level adaptive interventions and sequential, multiple assignment, randomized trials: Estimation and sample size considerations.

Boruvka, A. Almirall D. . Murphy, S. A. (submitted, under 2nd review). Assessing Time-Varying Causal Effect Moderation in Mobile Health: Modeling and Estimation Considerations for Intensive Longitudinal Intervention Data. [arXiv version ]

Nahum-Shani, I. Ertefaie, A. Almirall D. . Lu, Xi (Lucy); McKay, J.; Lynch, K. Oslin, D. Murphy, S. A. (submitted, under review). A SMART Data Analysis Method for Constructing Adaptive Treatment Strategies in Substance Use Disorders.

Kidwell, K. M. Seewald, N. J. Tran, B. Q. Almirall D. (submitted). Design and Analysis Considerations for Comparing Dynamic Treatment Regimens with Binary Outcomes from Sequential Multiple Assignment Randomized Trials .

Wodtke, G. T. Almirall D. (senior author) (submitted, under 2nd review). Analyzing causal effect heterogeneity with time-varying treatments and time-varying effect moderators: Structural nested mean models and regression-with-residuals estimation. Sociological Methodology .

Griffin, B. A. McCaffrey, D. Almirall D. . Burgette, L. Setodji, C. (submitted, under 2nd review). Chasing Balance and Other Recommendations for Improving Nonparametric Propensity Score Models. Journal of Causal Inference .

Accepted

Almirall D. . Chronis-Tuscano, A. (accepted January 2016, in press). Adaptive interventions in Child and Adolescent Mental Health. Journal of Clinical Child and Adolescent Psychology .

Hwanwoo, K. Ionides, E. Almirall D. (senior author) (accepted, June 2016). A Sample Size Calculator for SMART Pilot Studies. Society for Industrial and Applied Mathematics (SIAM): Undergraduate Research Online (SIURO) Journal.

Sherwood, N. E. Butryn, M. L. Forman, E. M. Almirall D. . Seburg, E. M. Crain, L. A. Kunin-Batson, A. S. Hayes, M. G. Levy, R. L. Jeffery, R. W. (accepted January 2016, in press). The BestFIT trial: A SMART approach to developing individualized weight loss treatments. Contemporary Clinical Trials .

Klasnja, P. Hekler, E. B. Shiffman, S. Boruvka, A. Almirall D. . Tewari, A. Murphy, S. A. (accepted December 2015, in press). Micro-randomized trials: An experimental design for developing just-in-time adaptive interventions. Health Psychology .

Lu, X. Nahum-Shani, I. Kasari, C. Lynch, K. G. Oslin, D. W. Pelham, W. E. Fabiano, G. Almirall D. (senior author) (accepted December 2015, in press). Comparing dynamic treatment regimes using repeated-measures outcomes: modeling considerations in SMART studies Statistics in Medicine . [Abstract ] [Technical Report of an older version of the manuscript is available from The Methodology Center at Penn State University ]

Kilbourne, A. M. Barbaresso, M. Lai, Z. Nord, K. Bramlet, M. Goodrich, D. E. Post, E. Almirall D. . Bauer, M. (accepted December 2015, in press). Improving Physical Health in Patients with Chronic Mental Disorders: 12-Month Results from a Randomized Controlled Collaborative Care Trial. Journal of Clinical Psychiatry,

Chronis-Tuscano, A. Wang, C. H. Strickland, J. Almirall D. . Stein, M. A. (accepted September 2015, in press). Moving Toward Personalized Treatment of Mothers with ADHD and Their At-Risk Children: A SMART Pilot. Journal of Clinical Child and Adolescent Psychology .

Almirall D. . DiStefano, C. Chang, Y. Shire, S. Lu, X. Nahum-Shani, I. Kasari, C. (accepted December 2015, in press). Adaptive interventions and longitudinal outcomes in minimally verbal children with ASD: Role of speech-generating devices. Journal of Clinical Child and Adolescent Psychology .

Gunlicks-Stoessel, M. Mufson, L. Westervelt, A. Almirall D. . Murphy S. A. (accepted 2014, in press). A Pilot SMART for Developing an Adaptive Treatment Strategy for Adolescent Depression. Journal of Clinical Child and Adolescent Psychology .

Kilbourne, A. M. Almirall, D. . Eisenberg, D. Waxmonsky, J. Goodrich, D. E. Fortney, J. C. Kirchner, J. E. Solberg, L. I. Main, D. Bauer, M. S. Kyle, J. Murphy, S. A. Nord, K. M. Thomas, M. R. (2014). Protocol: Adaptive Implementation of Effective Programs Trial (ADEPT): cluster randomized SMART trial comparing a standard versus enhanced implementation strategy to improve outcomes of a mood disorders program. Implementation Science . 9,132. DOI: 10.1186/s13012-014-0132-x.

Kilbourne, A. M. Almirall, D. . Goodrich, D. E. Lai, Z. Abraham, K. M. Nord, K. M. & Bowersox, N. W. (2014). Enhancing outreach for persons with serious mental illness: 12-month results from a cluster randomized trial of an adaptive implementation strategy. Implementation Science . 9(1), 163. DOI: 10.1186/s13012-014-0163-3.

Kilbourne, A. M. Abraham, K. M. Goodrich, D. E. Bowersox, N. W. Almirall D. . Lai, Z. Nord, K. M. (2014). Re-Engaging Veterans with Serious Mental Illness into Care: Preliminary Results (6 Month Outcomes) from a National Randomized Trial of an Enhanced versus Standard Implementation Strategy. Psychiatric Services, January, 66(1), 90-93. DOI: 10.1176/appi. ps.201300497. PMID: 25554233.

Peris, T. S. Compton, S. N. Almirall D. . Kendall, P. C. Albano, A. M. Walkup, J. T. March, J. S. Birmaher, B. Ginsburg, G. S. Sherrill, J. Rynn, M. A. McCracken, J. T. Keeton, C. P. Sakolsk, D. Iyengar, S. Piacentini, J. C. (accepted 2014, in press). Trajectories of Change in Youth Anxiety during Cognitive Behavior Therapy. Journal of Consulting and Clinical Psychology. PMID: 25486372.

Ramchand R. Griffin, B. A. Slaughter, M. Almirall D. . McCaffrey, D. F. (accepted 2014; in press). Do improvements in substance use and mental health symptoms during treatment translate to long-term outcomes in the opposite domain? Journal of Substance Abuse Treatment.

Kilbourne, A. M. Bramlett, M. Barbaresso, M. M. Nord, K. M. Goodrich, D. E. Zongshan, L. Post, E. P. Almirall D. . Verchinina, L. Duffy, S. A. Bauer, M. S. (accepted July 2014; in press). SMI Life Goals: Description of a Randomized Trial of a Collaborative Care Model to Improve Outcomes for Persons with Serious Mental Illness. Contemporary Clinical Trials.

Collins, L. Nahum-Shani, I. Almirall, D. (2014). Optimization of behavioral dynamic treatment regimens based on the sequential, multiple assignment, randomized trial (SMART). Clinical Trials, June 5:11(4):426-434. DOI:10.1177/1740774514536795. PMID: 24902922. PMCID: PMC4257903

Almirall D. . Nahum-Shani, I. Sherwood, N. E. Murphy S. A. (2014). Introduction to SMART Designs for the Development of Adaptive Interventions: With Application to Weight Loss Research. Translational Behavioral Medicine, 4:260-274. DOI: 10.1007/s13142-014-0265-0 [Technical Report of an older, longer, and not-as-polished version of this manuscript is available from The Methodology Center at Penn State University ]

Kasari, C. Kaiser, A. Goods, K. Nietfeld, J. Mathy, P. Landa, R. Murphy, S. A. Almirall D (senior author) (accepted March 2014, in press). Communication Interventions for Minimally Verbal Children with Autism: Sequential Multiple Assignment Randomized Trial. Journal of the American Academy of Child and Adolescent Psychiatry . DOI:10.1016/j. jaac.2014.01.019

This manuscript was discussed by Dr. Helen Tager-Flushberg of Boston University; see here .

Autism Speaks. the world's leading autism science and advocacy organization, wrote a two-part blog about this research .

Compton, S. N. Peris, T. S. Almirall D. Birmaher, B. Sherrill, J. Kendall, P. C. March, J. S. Gosch, E. A. Ginsburg, G. S. Rynn, M. A. Piacentini, J. C. McCracken, J. T. Keeton, C. P. Suvey, C. Aschenbrand, S. G. Sakolsky, D. Iyengar, S. Walkup, J. T. Albano, A. M (accepted 2014, in press). Predictors and Moderators of Treatment Response in Childhood Anxiety Disorders: Results from the CAMS Trial. Journal of Consulting and Clinical Psychology . DOI:10.1037/a003548

Griffin, B. A. Ramchand R. Almirall D. . Slaughter, M. Burgette, L. McCaffrey, D. F. (accepted Jan 2014; in press). Estimating the causal effects of cumulative treatment episodes for adolescents using marginal structural models and inverse probability of treatment weighting. Drug and Alcohol Dependence .

Schuler, M. Griffin, B. A. Ramchand, R. Almirall D. . McCaffrey, D. F. (2014). Effectiveness of Treatment for Adolescent Substance Use: Is Biological Drug Testing Sufficient? Journal of Studies on Alcohol and Drugs . 75, 358-370.

Kilbourne, A. M. Abraham, K. M. Goodrich, D. E. Bowersox, N. W. Almirall D. . Lai, Z. Nord, K. M. (2013). Cluster randomized adaptive implementation trial comparing a standard versus enhanced implementation intervention to improve uptake of an effective re-engagement program for patients with serious mental illness. Implementation Science . 8(136). DOI: 10.1186/1748-5908-8-136

Almirall D. . McCaffrey, D. F. Griffin B. A. Ramchand R. Yuen R. Murphy S. A. (accepted June 2013; in press). Time-varying effect moderation using the structural nested mean model: estimation using inverse-weighted regression-with-residuals. Statistics in Medicine . [Technical Report of an older version of the manuscript is available from The Methodology Center at Penn State University ]

Yancy, W. S. Coffman, C. J. Geiselman, P. J. Kolotkin, R. L. Almirall D. . Oddone, E. Z. Mayer, S. B. Gaillard, L. A. Turner, M. Smith, V. A. Voils, C. I. (2013). Considering Patient Diet Preference to Optimize Weight Loss: Design Considerations of a Randomized Trial Investigating the Impact of Choice. Contemporary Clinical Trials . 35(1):106-116

McCaffrey, D. F. Griffin, B. A. Almirall D. . Slaughter, M. E. Ramchand, R. Burgette, L. F. (2013, e-pub). A Tutorial on Propensity Score Estimation for Multiple Treatments using Generalized Boosted Models. Statistics in Medicine. DOI: 10.1002/sim.5753

Almirall D. . Compton S. N. Rynn M. A. Walkup J. T. Murphy S. A. (2012). SMARTer Discontinuation Trial Designs for Developing an Adaptive Treatment Strategy. Journal of Child and Adolescent Psychopharmacology 22(5):364-74. DOI: 10.1089/cap.2011.0073. PMID: 23083023. PMCID: 3482379. [Technical Report of an older version of the manuscript is available from The Methodology Center at Penn State University ]

Nahum-Shani I. Qian M. Almirall D. . Pelham W. E. Gnagy B. Fabiano G. Waxmonsky J. Yu J. Murphy S. A. (accepted 2012; in press). Experimental Design and Primary Data Analysis Methods for Comparing Adaptive Interventions. Psychological Methods. [Technical Report of an older version of the manuscript is available from The Methodology Center at Penn State University ]

Nahum-Shani I. Qian M. Almirall D. . Pelham W. E. Gnagy B. Fabiano G. Waxmonsky J. Yu J. Murphy S. A. (accepted 2012; in press). Q-Learning: A Data Analysis Method for Comparing Adaptive Interventions. Psychological Methods. [Technical Report of an older version of the manuscript is available from The Methodology Center at Penn State University ]

Almirall D. . Lizotte, D. Murphy S. A. (2012). SMART Design Issues and the Consideration of Opposing Outcomes, a Discussion of Evaluation of Viable Dynamic Treatment Regimes in a Sequentially Randomized Trial of Advanced Prostate Cancer by Wang, Rotnitzky, Lin, Millikan, and Thall. Journal of the American Statistical Association (Case Studies and Applications) 107(498):509-12.

Almirall D. . Compton S. N. Gunlicks-Stoessel M. Duan N. Murphy S. A. (2012). Designing a Pilot Sequential Multiple Assignment Randomized Trial for Developing an Adaptive Treatment Strategy. Statistics in Medicine 31(17):1887-902. DOI: 10.1002/sim.4512. PMID: 22438190. PMCID: 3399974. [Technical Report of an older version of the manuscript is available from The Methodology Center at Penn State University ]

Almirall D. . McCaffrey, D. F. Ramchand R. Murphy S. A. (2013, print; 2011, e-pub). Subgroups Analysis when Treatment and Moderators are Time-varying. Prevention Science . 14(2):169-78.

Franklin M. E. Sapyta J. Freeman J. Khanna M. Compton S. N. Almirall D. . Moore P. Choate-Summers M. Garcia A. Edson A. L. Foa E. B. March J. S. March J. (2011). Cognitive-Behavior Therapy Augmentation of Pharmacotherapy in Pediatric Obsessive Compulsive Disorder: The Pediatric OCD Treatment Study II (POTS II) Randomized, Controlled Trial. Journal of American Medical Association . 306(11):1224-32. PMID: 21934055. PMCID: 3495326.

Lin P. H. Wang Y. Grambow S. C. Goggins, W. Almirall D. (2011). Dietary Saturated Fat Intake Is Negatively Associated With Weight Maintenance Among the PREMIER Participants. Obesity . 20(3):571-5. DOI: 10.1038/oby.2011.17.

Bosworth H. B. Almirall D. . Weiner B. J. Maciejewski M. Kaufman M. A. Powers B. J. Oddone E. Z. Shoou-Yih D. L. Damush T. Newell M, Smith V. Anderson D. Roumie C. and Jackson G. L. for HTN-IMPROVE Investigators (2010). The Implementation of a Translational Study Involving a Primary Care Based Behavioral Program to Improve Blood Pressure Control: The HTN-IMPROVE Study Protocol. Implementation Science . 5(54)

Sánchez-Ortuño M. M. Edinger J. D. Almirall D. . Means M. K. (2010). Home Is Where Sleep Is: An Ecological Approach to Test the Validity of Actigraphy for the Assessment of Insomnia. Journal of Clinical Sleep Medicine . 6(1):21-29

Almirall D. . Ten Have T. Murphy S. A. (2010, March). Structural Nested Mean Models for Assessing Time-Varying Effect Moderation. Biometrics . 66(1):131-139.

Gellad Z. F. Almirall D. . Provenzale D. Fisher D. A. (2009). Time from Positive Screening Fecal Occult Blood Test to Colonoscopy and Risk of Neoplasia. Digestive Disease and Sciences . 54(11):2497-2502.

Yancy W. S. Almirall D. . Maciejewski M. L. Kolotkin R. L. McDuffie J. R. Westman E. C. (2009). Effects of Two Weight Loss Diets on Health-related Quality of Life. Quality of Life Research . 18(3):281-89.

Mithas S. Almirall D. . Krishnan M. S. (2006). Do CRM Systems Cause One-to-One Marketing Effectiveness? Statistical Science . 21(2):223-233. (Not federally funded research.) [software ]

Bray B. C. Almirall D. . Zimmerman R. S. Lynam D. Murphy S. A. (2006). Assessing the Total Effect of Time-varying Predictors in Prevention Research. Prevention Science . March; 7(1): 1-17.

Newburger J. W. Wypij D. Bellinger D. C. du Plessis A. J. Kuban K. C. Rappaport L. A. Almirall D. . Wessel D. L. Jonas R. A. Wernovsky G. (2003). Length of Stay After Infant Heart Surgery is Related to Cognitive Outcome at Age 8 Years. Journal of Pediatrics . July; 143(1): 67-73. PMID: 12915826.

Book Chapters and Other Publications

Almirall D. . Shih, W. (accepted 2016, in press). SMART Research Design. The SAGE Encyclopedia of Abnormal and Clinical Psychology.

Almirall D. . Nahum-Shani, I. Schulenberg, J. (2015). Adaptive Interventions for Adolescents and their Families and Communities. Society for Research on Adolescence, Tuesday, April, 21, President's Blog .

Almirall D. . Blalock, J. A. (2014). Summary of the SRNT Treatment Network Webinar: Getting SMART About Developing Individualized Sequences of Health Interventions. Nicotine & Tobacco Research, February; 16(2):252. DOI:10.1093/ntr/ntt197. PMID: 24302636

Almirall D. . Coffman C. J. Yancy W. S. Murphy S. A. (2010). Maximum Likelihood Estimation of the Structural Nested Mean Model Using SAS PROC NLP. Analysis of Observational Health-Care Data Using SAS. D. Faries, A. Leon, J. M. Haro, B. Obenchain (Editors).

Murphy S. A. Almirall D. (2009). Dynamic Treatment Regimens. Encyclopedia of Medical Decision Making. M. W. Kattan (Editor). Thousand Oaks, CA: Sage Publications.

Mithas S. Almirall D. . Krishnan M. S. (2009). A potential outcomes approach to assess causality in information systems research . In R. J. Kauffman and P. P. Tallon (Eds.) Economics, Information Systems, and Electronic Commerce Research II: Advanced Empirical Methodologies. Armonk, NY: M. E. Sharpe.

Work in Progress

Almirall D. . Lu, X. Kasari, C. Nahum-Shani, I. (in progress). Small sample considerations in the comparison of dynamic treatment regimens using SMART data: With applications to Autism.

Hall, K. Nahum-Shani, I. August G. Patrick, M. Murphy, S. A. Almirall D. (senior author) (in progress). Adaptive Intervention Designs in Substance Use Prevention. Advances in Prevention Science. Z. Sloboda, H. Petras, L. Robertson, R. Hingson (Editors).

Almirall D. . Lu, X. Kasari, C. Nahum-Shani, I. (in progress). Variance reduction in the comparison of dynamic treatment regimens using SMART data: With applications to Autism and ADHD.

Almirall D. . Lu, X. Griffin, B. A. Burgette, L. Setodji, C. McCaffrey, D. (in progress). Accounting for within-person residual correlation in IPTW estimation of the repeated measures marginal structural model: Practice and pitfalls.

Tao, Y. Wang, L. and Almirall D. (in progress). Tree-based Reinforcement Learning for Estimating Optimal Dynamic Treatment Regimens.

Almirall D. . Nahum-Shani, I. and Murphy, S. A. (book project underway). Getting SMART about Adaptive Interventions: Case Studies in the Behavioral, Biobehavioral and Educational Sciences.

Talks

I stopped listing talks here. Instead, see this page which is more up to date.

Almirall D. Lu, X. Kasari, C. Nahum-Shani, I. Murphy, S. A. (2014, March). On the Comparison of Adaptive Interventions Using Data Arising from a SMART: With Application to Autism. Department of Biostatistics, Columbia University, New York, NY. [slides ]

Almirall D. McCaffrey, D. F. Griffin, B. A. Ramchand, R. Murphy, S. A. (2013, February). Examining moderated effects of additional adolescent substance use treatment: Structural nested mean model estimation using inverse-weighted regression-with-residuals. Department of Epidemiology and Biostatistics, University of Maryland School of Medicine, Baltimore, MD. [slides ]

Almirall D. Collins, L. Murphy, S. A. (2012, November). Getting SMART about Developing Individualized Sequences of Health Interventions. Innovative Methods Program for Advancing Clinical Trials (IMPACT), Second IMPACT Symposium on ``Clinical Trials in the Era of Personalized Medicine," Raleigh, NC. [slides ]

Almirall D. Murphy, S. A. (2012, October). Piloting and Sizing Sequential Multiple Assignment Randomized Trials in Dynamic Treatment Regime Development. Advances in Interdisciplinary Statistics and Combinatorics, University of North Carolina, Greensboro, NC. [slides with notes ]

Almirall D. McCaffrey, D. F. Griffin, B. A. Ramchand, R. Murphy, S. A. (2012, September). Examining moderated effects of additional adolescent substance use treatment: Structural nested mean model estimation using inverse-weighted regression-with-residuals. Department of Statistics, George Mason University. [slides ]

Almirall D. (2012, July). Variable Selection for Individualized Treatment Decision-Making. Joint Statistical Meetings, San Diego, California. [slides ]

Almirall D. McCaffrey, D. F. Griffin, B. A. Ramchand, R. Murphy, S. A. (2012, July). Examining moderated effects of additional adolescent substance use treatment: Structural nested mean model estimation using inverse-weighted regression-with-residuals. Institute of Mathematical Statistics, Asia Pacific Rim Meeting, Tsukuba, Japan. [slides ]

Almirall D. Patrick, M. (2012, March). An Adaptive Intervention for Reducing College Student Alcohol-related Consequences: A SMART Pilot Study Proposal. Center for the Study of Health and Risk Behaviors, University of Washington, Seattle, WA. [slides ]

Almirall D. Compton S. N. Murphy S. A. (2012, March). Developing Adaptive Health Interventions: Getting SMART. AIMS Center, University of Washington, Seattle, WA. [slides ]

Almirall D. McCaffrey D. F. Griffin B. A. Ramchand, R. Murphy S. A. (2011, October). Examining moderated effects of additional adolescent substance use treatment: Structural nested mean model estimation using inverse-weighted regression-with-residuals. RAND, Pittsburgh, PA. [slides ]

Almirall D. McCaffrey D. F. Griffin B. A. Ramchand, R. Murphy S. A. (2011, December). Examining moderated effects of additional adolescent substance use treatment: Structural nested mean model estimation using inverse-weighted regression-with-residuals. University of Michigan, Department of Biostatistics Seminar Series, Ann Arbor, MI. [slides ]

Almirall D. McCaffrey D. F. Griffin B. A. Ramchand, R. Murphy S. A. (2011, October). Examining moderated effects of additional adolescent substance use treatment: Structural nested mean model estimation using inverse-weighted regression-with-residuals. International Conference on Health Policy Statistics, Cleveland, OH. [slides ]

Almirall D. Compton S. N. Murphy S. A. (2011, April). Experimental Designs for Developing Adaptive Treatment Strategies. Pre-conference Workshop on Optimizing Behavioral Interventions, Society of Behavioral Medicine, Washington, DC. [slides ]

Almirall D. Ten Have T. Murphy S. (2010, January). Structural Nested Mean Models for Assessing Time-varying Effect Moderation. Prevention Science and Methodology Group. University of South Florida. [slides ] [Recording (requires Java Elluminate Live!)]

Almirall D. Compton S. N. Murphy S. (2009, September). Experimental Designs for Developing Adaptive Treatment Strategies: With Application to the Management of Child Anxiety. Health Services Research & Development Seminar Series, Durham, NC.[slides ]

Almirall D. (2009, September). Causal Effect Moderation (Modifcation) When Treatment or Exposure is Time-Varying: When to use the MSM versus the SNMM? Federal Interagency Subgroups Analysis Meeting, Bethesda, MD. [slides ]

Almirall D. Compton S. Murphy S. A. (2009, August). Experimental Designs for Developing Adaptive Treatment Strategies: With Application to the Management of Child Anxiety. Institute of Psychiatry, Sao Paulo, Brazil. (Invited Seminar) [slides ]

Almirall D. Ten Have T. Murphy S. (2009, May). Structural Nested Mean Models for Assessing Time-varying Effect Moderation. Atlantic Causal Modelling Conference, University of Pennsylvania, Philadelphia. (Invited Seminar) [slides ]

Almirall D. McCaffrey D. Morral A. Murphy S. A. (2008, May). Causal Effect Moderation with Application to Level of Care Matching for Adolescent Substance Abuse Treatment. Society for Prevention Research, San Francisco, CA. (Invited Seminar) [slides ]

Almirall D. Compton S. Murphy S. A. (2008, May). Experimental Designs for Developing Adaptive Treatment Strategies: With Application to the Management of Child Anxiety. NIMH-NCDEU Conference, Phoenix, AZ. (Invited Seminar) [slides ]

Almirall D. Ten Have T. Murphy S. A. (2007, September). Structural Nested Mean Models for Assessing Time-varying Effect Moderation: With Applications in Mental Health. Biostatistics Seminar Series, Department of Statistics, North Carolina State University, Raleigh. [slides ]

Almirall, D. (2007, September) Assessing the Effects of Time-Varying Predictors and Treatments: Conceptual Issues. Health Services Research & Development Seminar Series, Durham VA Medical Center. [slides ]

Almirall D. Ten Have T. Murphy S. (2007, July). Structural Nested Mean Models for Assessing Time - Varying Effect Moderation: With Applications in Mental Health. Joint Statistical Meetings Conferences, Salt Lake City, UT.[slides ]

Workshops

My colleagues (Billie Nahum-Shani and Susan A. Murphy ) and I have given numerous workshops on the topic of Adaptive Interventions and Sequential Multiple Assignment Randomized Trials. Click here for more details on future and past workshops.

Almirall D. Ten Have T. (2008, November). Examining the Effects of Time-varying Treatments or Predictors. Association for Cognitive and Behavioral Therapies, Orlando, Florida. [slides ]

Posters

Almirall D. Ten Have T. Murphy S. (2007, March). Structural Nested Mean Models for Assessing Time - Varying Effect Moderation: With Applications in Mental Health. Michigan Student Symposium for Interdisciplinary Statistical Sciences, University of Michigan, Ann Arbor. [poster ]

Current

Tim NeCamp. Department of Statistics, University of Michigan

Tianshuang Wu. Department of Statistics, University of Michigan

Kelly Hall. Department of Statistics and International Studies

Past

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